• Title/Summary/Keyword: Differentiation Strategy

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Proteome Analysis for 3T3-L1 Adipocyte Differentiation

  • Rahman, Atiar;Kumar, Suresh G.;Lee, Sung-Hak;Hyun, Sun-Hwang;Kim, Hyun-Ah;Yun, Jong-Won
    • Journal of Microbiology and Biotechnology
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    • v.18 no.12
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    • pp.1895-1902
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    • 2008
  • Adipose tissue is an important endocrine organ involved in the control of whole body energy homeostasis and insulin sensitivity. Considering the increased incidence of obesity and obesity-related disorders, including diabetes, it is important to understand thoroughly the process of adipocyte differentiation and its control. Therefore, we performed a differential proteome mapping strategy using two-dimensional gel electrophoresis combined with peptide mass fingerprinting to identify intracellular proteins that are differentially expressed during adipose conversion of 3T3-L1 pre-adipocytes in response to an adipogenic cocktail. In the current study, we identified 46 differentially expressed proteins, 6 of which have not been addressed previously in 3T3-L1 cell differentiation. Notably, we found that phosphoribosyl pyrophosphate synthetase (PRPS), a regulator of cell proliferation, was preferentially expressed in pre-adipocytes than in fully differentiated adipocytes. In conclusion, our results provide valuable information for further understanding of the adipogenic process.

Outcome and Antecedent of Organizational Effectiveness: Moderation Effect of Strategy

  • KIM, Boine
    • East Asian Journal of Business Economics (EAJBE)
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    • v.10 no.2
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    • pp.1-17
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    • 2022
  • Purpose - This exploratory study analyzes the performance of the business from the HRM point of view. Analyzed the influence of HRM and organization effectiveness on business performance. Also moderating effect of the strategy is analyzed. Research design, data, and methodology - Two outcome variables are measured, non-financial performance and financial performance. Two organizational effectiveness variables are measured, job satisfaction and organizational commitment. And two HRM areas are measured, HRM practice and organizational culture. Finally, two strategies are measured as moderators, market strategy and product/service strategy. This study analyzed employees of 554 from the 7th HCCP. This study used SEM and MCFA. Result - The results of turnover intention, growth rate, and profit rate verified the influence of HRM and organizational effectiveness. Overall results showed a contrary effect of education & training system implement and participation on job satisfaction and organizational commitment. Among organizational culture, innovation and relation positively affect job satisfaction and organizational commitment. However, antecedents influencing turnover intention, growth rate, and profit rate bear no resemblance. And the MCFA result shows that strategy's group differentiation analysis is meaningful in turnover intention not in financial performance. Conclusion - Based on this study result, management suggestions for turnover intention, growth rate, profit rate, and organizational effectiveness are made. Especially, due to the company's strategy.

Customer Buying Process Based B2C Differentiation Strategy Analysis (고객 구매 프로세스 기반 B2C 차별화 전략 분석)

  • Gu, Ja-Heon;Park, U-Seong;Han, Hyeon-Su
    • Proceedings of the Korean Operations and Management Science Society Conference
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    • 2007.11a
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    • pp.488-492
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    • 2007
  • In this study, we investigated how to distinguish customer delivered value to re-purchasing in fierce B2C industry. To identify key managerial variables that could distinctively impact re-purchasing, we first identified customer value proposition as per the customer buying decision process. Next, core value propositions of choice efficiency and competitive price are defined to determine vendor satisfaction during the searching stage and purchasing stage. The trust level is also introduced in the sense of reflecting confirmation to guarantee after purchase security. Then, significant managerial variables to impact on core value propositions are extracted. The resulting structural model illustrated that search convenience and quality assurance affect the choice efficiency, and re-purchase intention is strongly explained by both the vendor satisfaction and trust level. The empirical testing results also support that transaction cost reduction is key determinant of shopping at the Internet shopping mall. Furthermore, trust level should be combined to induce re-purchasing in addition to transaction cost savings.

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A Study on the Relationship between New Product Development Strategies and New Product Outcomes (신제품개발전략의 유형과 성과에 관한 연구)

  • 김지대;김기영
    • Journal of the Korean Operations Research and Management Science Society
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    • v.21 no.3
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    • pp.11-46
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    • 1996
  • The objectives of this research paper are to identify the types of the firm's new product development strategy and their characteristics about business strategy, to examine the effect of each type on new product outcomes, and to explore the contingency variable influencing the relationship between these types and new product outcomes. The result of the research are summarized as follows : First, in terms of both the resource allocation for product innovativeness and technology acquisition method, this study suggests 9 types of the firm's new product development strategies- Type 1 (pursuing low innovative products/relying on external technology), Type 2 (pursuing low innovative products oriented/relying on internal technology), Type 3 (pursuing low innovative products/relying on mixed technology), Type 4 (pursuing high innovative products/relying on internal technology), Type 6(pursuing high innovative products /relying on mixed technology), Type 7 (balancing low and high innovative products/relying on external technology), Type 8 (balancing low and high innovative products/relying on internal technology), Type 9 (balancing low and high innovative products/relying on mixed technology). Second, these 9 types are deeply associated with the firm's business strategic variables such as product differentiation and market differentiation, and exhibit different level of both technical and commercial performance of new products. Finally, the effects of these types on new product outcomes are different according to industrial environment and firms' characteristics with respect to size and technological capability.

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The Effect of competitive strategy on Firms' Export Performance : Focusing on the Moderating Effect of Entrepreneurial Orientation (중국 중소기업의 경쟁전략이 수출성과에 미치는 영향 : 기업가 지향성의 조절 효과를 중심으로)

  • Sangyun Han;Hongchao Liu
    • Korea Trade Review
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    • v.47 no.4
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    • pp.103-124
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    • 2022
  • For venturing into international markets, small and medium enterprises (SMEs) have not only emphasized internal resources but entrepreneurial orientation has also become the need of the day due to its significant role in increasing firm's competitive capabilities. Although research indicates that the competitive strategies can significantly impact export performance, minor attention is given to the relationship between entrepreneurial orientation, business competitive strategy and export performance of small and medium enterprises (SMEs). This study scrutinizes the effect of each dimension of entrepreneurial orientation (i.e., innovativeness, risk-taking, and proactiveness) and each of generic competitive strategies (i.e., cost leadership and differentiation) on the export performance of Chinese SMEs. And we investigated the moderating effect of entrepreneurial orientation on the relationship between the competitive strategies and export performance. We surveyed 217 Chinese SMEs through a structured questionnaire. For the data analysis and hypotheses testing, we used AMOS. 27. The findings display that differentiation and cost leadership strategies significantly improve export performance. The innovativeness, risk-taking and proactiveness also spur Chinese SME's export performance. Further we find that adding entrepreneurial orientation significantly improves our model of the relationship between the competitive strategies and export performance. Thus, our study extends the entrepreneurial orientation literature and provides interesting new insights into how entrepreneurial orientation helps firms create more successful export operations.

A Preliminary Study on Niche Marketing Strategy for the Medium-small Size Family Restaurant (중소규모 패밀리 레스토랑의 틈새마케팅전략에 관한 탐색적 연구)

  • Kwon Kum-Tack
    • Management & Information Systems Review
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    • v.18
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    • pp.115-132
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    • 2006
  • The main findings of this study are summarized as follows; 1) For medium-small size Family Restaurant(FR) in the FR market, nowadays, survival is the key issue. If the medium-small size FR is to survive and continue to grow under this competitive environment, it must pursued the efficiency of management with niche marketing strategy. 2) This study is to describe the niche marketing strategy for medium-small size FR. Strategic niche marketing must be based on the target market, market positioning and strategic marketing mix. 3) Medium-small size FR needs to develop the marketing mix factors for the niche marketing strategy. It needs to make customers understand what the FR differs from current and potential competitors. Essentially the medium-small size FR must take a competitive advantage. Hence it will appeal to a substantial number of the segments customers. 4) In using niche marketing strategy, a medium-small size FR must establish the objectives, select the tools, develop the decisions on product differentiation, market segmentation and positioning under various strategic niche marketing factors 5) By carrying out the niche marketing strategy on the target market, customer's desire can be further fulfilled. When management efficiency is improved, we can better cope with changing environment.

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The Effects of Fitness Between Centralization of IT Activities and Organizational Strategy on Information System Performance. (정보기술 활동의 집중화와 조직 전략간의 적합도가 정보시스템 성과에 미치는 영향에 관한 연구)

  • 한경일
    • The Journal of Information Technology
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    • v.2 no.1
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    • pp.131-147
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    • 1999
  • According to literature review, fitness between IT activities and organizational strategy enhances performance. Theoretical research says that centralized company in IT activities is appropriate to cost-leadership strategy and decentralized company in IT activities is appropriate to differentiation strategy. But there are very few empirical research. The purpose of this study is to attest whether fitness between IT activities and organizational strategy enhances the information system performance. But the results of this field study were not consistent with literature that fitness of two independent variables enhance performance. So we should take other contingency variables such as organizational structure, culture etc. into consideration to investigate relationship between IT activities and strategy.

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The Growth of Private Enterprises in the 1990s and Regional Development in China (1990년대 중국 사영기업의 성장과 지역발전)

  • Lee, Won-Ho
    • Journal of the Economic Geographical Society of Korea
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    • v.8 no.2
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    • pp.285-299
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    • 2005
  • The economic reform in China since 1978 has been increasingly sped up and deepened. The recent development of private enterprises, especially, has significant economic and political implications, whereas its regional differentiation has considerable impacts on both the development potential of certain regions and overall regional growth pattern. This study aims to understand the regional pattern of private enterprise growth as well as the institutional change which has structured the growth process. The development of private enterprises turned out to be closely tied to the marketization strategy of dual-track system and policy needs to reduce the unemployment level in both urban and 겨ral China. The regional pattern of the private enterprise growth can be characterized as ever-increasing spatial differentiation. Based on the basic statistical analysis results, it is argued that the private enterprise growth is closed related with the marketization level of the regional economy. Therefore, the strategy of developing private sector will be more important in shaping the regional development path as well as potential.

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A Study on Elements of CM Firms' Competitive Strategy (경쟁전략요소에 대한 CM기업의 인식에 관한 연구)

  • Baek, Seung-Ryong;Kim, Han Soo
    • Korean Journal of Construction Engineering and Management
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    • v.14 no.5
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    • pp.122-130
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    • 2013
  • As the level of competition has increased in the construction management market, it becomes a critical issue for CM firms to secure competitive edges. The objective of the study is to investigate elements of competitive strategy as perceived by CM firms and to discuss key features and implications. Michael Porter's Competitive Strategy Model was used as a framework to analyse the elements under three strategy categories. A major finding includes that Differentiation Strategy is generally perceived most important strategy category but, depending on the group to which a CM firm belongs, there exist a gap in the perception. However, regardless of the group, Cost Leadership is commonly considered least important strategy category. In particular, lowest-bidding strategy element showed the least importance. Understanding CM firms' perceptions on elements of competitive strategy provides an insight into CM firms' current strategy directions and can be useful for future tuning in a firms' own strategy.