• Journal of Korean Academy of Fundamentals of Nursing
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• v.26 no.4
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• pp.221-230
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• 2019

Purpose: This study was done to examine incidence of diarrhea and explore factors influencing occurrence of diarrhea in patients admitted to intensive care units (ICU). Methods: For this retrospective research, data based on inclusion criteria were collected from the electronic medical records for 142 patients admitted to a university hospital ICU from September 2014 to August 2015. Statistical analysis was conducted using SPSS/WIN 22.0 program. Results: Incidence of diarrhea was 53.5% during the 12-month study period. Diarrhea occurred at 4.54 days and continued for 1.79 days on average. Average total frequency of diarrhea was 5.56 times. Increased ICU stay, enteral nutrition, and infection state were significant predictors of the occurrence of diarrhea. Infection increased risk of diarrhea 3.4 times and enteral nutrition increased risk of diarrhea to 2.2 times greater than patients not receivng enteral nutrition. Conclusion: Diarrhea in ICU patients is associated with multiple factors that should be considered to implement preventive strategies. Infection control should be emphasized, and close monitoring of diarrhea should be provided for those with enteral nutrition. Further studies are warranted to determine standardized clinical definition of diarrhea and diarrhea risk factors in ICU patients with different levels of severity and comorbidity.

• Journal of Animal Science and Technology
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• v.52 no.4
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• pp.281-286
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• 2010

In this study, feeding fermented colostrum to Holstein calves was investigated to find out the effects on their growth and inhibition of diarrhea. The results of this study showed that the mixture of L. rhamnosus and E. faecium would be proper bacteria for fermentation of colostrum because of favorable odor, inhibition of coliform bacteria and high number of lactic acid bacterial count. Among the groups of calves fed 0, 5, 10 and 20% of fermented colostrums, average body weight gain for 28 days on feeding fermented colostrum were 16.6, 16.6, 17.4 and 18 kg, respectively showing that calves fed 20% fermented colostrum achieved the highest body weight gain. Occurrence of diarrhea due to feeding various levels of fermented colostrum was also recorded. Three calves out of 5 suffered diarrhea in 0%, 5%, and 20% group, on the other hand, all 5 calves suffered diarrhea in 10% group. Diarrhea persisted for durations were 2.7, 2.4, 4.0, and 2.4 days in 0, 5, 10, and 20% group, respectively. Fermented colostrum did not prevent the occurrence of diarrhea. In overall, addition of fermented colostrum above 10% level showed favorable effects in gaining body weight under the conditions of adding more portions of the fermented colostrum either for 14 days or longer feeding period of the fermented colostrum. On the other hand, fermented colostrum showed no beneficial effect in prevention of diarrhea in this study.

• Journal of Korean Biological Nursing Science
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• v.10 no.2
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• pp.105-112
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• 2008

Purpose: The purpose of this study was to investigate the difference in the incidence of diarrhea among the subjects given hypertonic and isotonic nutrients to the nasogastric tube feeding patients in the a critical care setting. Methods: This study is aquasi-experimental study with a pre & post-test design. The sample size of 40 was calculated based on Cohen's formula (1988). The total of 40 subjects who signed the informed consent were randomly selected and divided evenly into two groups, experimental and control group. Results: There are no significant differences between the two groups in homogeneity test (sex, age, albumin level, the use of antibiotics, antacid, and $H_2$ blocker). However, the frequencies of occurrence in diarrhea according to the density of nutrients formulation indicated a statistical difference at the level of .005 (p=.001): diarrhea occurred in four of 20 (20%) of the experiment group, but 14 (70%) of the control group. Also the onset date of diarrhea in the experiment group is later than that of the control group. Conclusion: The research findings suggest that we should begin with low density nutrients for nasogastric tube feeding, and increase its density gradually to decrease diarrhea incidence in the critical care setting.

• Asian-Australasian Journal of Animal Sciences
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• v.14 no.5
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• pp.640-645
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• 2001

In order to evaluate the change in plasma and fecal mineral content of calves to 6 days of age, and to clarify the relationship between electrolyte status and fecal consistency in calves at 6 days of age, data were collected from 52 Holstein calves. Fecal DM and Na of calves decreased at 6 days of age, but fecal Ca, P, Mg, K, Fe and Zn increased. Plasma Ca, inorganic P, Mg, Na, and Fe as well as blood hematocrit and hemoglobin of calves decreased at 6 days of age, but plasma alkaline phosphatase increased. Colostral Ca, P, Mg, Fe and Zn decreased with time postpartum, but colostral Na and K were not affected. The high plasma Na and K of calves at 6 days of age were influenced by the values at birth. There were negative correlations between fecal DM and fecal Na, and fecal K, of calves at 6 days of age, negative correlations between fecal DM and plasma Na, with plasma K. Plasma and fecal Na as well as plasma and fecal K of calves at 6 days of age were increased by the occurrence of diarrhea. These results suggest that the electrolyte status of calves at 6 days of age is adversely affected by the occurrence of diarrhea, and high plasma K and Na of calves at 6 days of age may be partly due to the electolyte status of calves at birth.

• Journal of Veterinary Clinics
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• v.26 no.6
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• pp.578-581
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• 2009

A 25-day-old, Korean indigenous calf was presented with a 10 days history of respiratory disorders and bloody diarrhea, and died. This calf was extremely unthrifty compared to others and had evidence of chronic diarrhea based on matting of feces in the hair of the tail and perineum. Ecchymotic hemorrhages were observed on multiple organs at necropsy. Bovine viral diarrhea virus (BVDV) infection was identified by RT-PCR. The phylogenetic analysis showed that this case belonged to BVDV-2a subgroup and was related to highly pathogenic USA isolate 890 (U18059). This case provided evidence for circulation of BVDV-2 in Republic of Korea. The occurrence of BVDV-2 was also reconfirmed.

• Journal of Veterinary Clinics
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• v.26 no.6
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• pp.582-585
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• 2009

Bovine viral diarrhea virus (BVDV) is an economically important worldwide disease in livestock industry. In this study, the occurrence of BVDV in Korean indigenous cattle was performed by RT-PCR using nasal swab. Twelve of 21 cattle were identified as BVDV positive and classified as persistently infected (PI). These animals showed the occurrence of diseases such as diarrhea and pneumonia. BVDV PI outbreaks were found mostly in PI calves. Sequencing and phylogenetic analysis based on the 5'-untranslated region (UTR) showed that our case belonged to BVDV-2a. These results suggested that the nasal swab sampling was available method for the detection of PI animals, underscoring the need for BVDV control strategies in Korean indigenous cattle.

• Childhood Kidney Diseases
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• v.7 no.1
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• pp.77-81
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• 2003

Diarrhea-associated hemolytic uremic syndrome is rarely accompanied by complications requiring surgical intervention. We report a case of the diarrhea-associated hemolytic uremic sydrome which developed simultaneously with an acute appendicitis.

• Korean Journal of Veterinary Research
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• v.37 no.2
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• pp.451-456
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• 1997

120 heads of korean native calves were examined of serum protein by using cellulose acetate electrophoresis. During 20 days since the calves were purchased, serum protein, fibrinogen values and plasma : fibrinogen ratio were examined in the calves with respiratory and diarrheal disease. The result obtained in this investigation were as follows : 1. Among the 120 heads of calves that were purchased from market, 14 heads(22%) of calves were occurred respiratory disease, and 12 heads(20%) of calves are occurred diarrhea. Occurrence of respiratory disease was 14.5(4~20) days in average and diarrhea was 9.6(2-15) days after they had been purchased. 2. Serum protein fraction were analyzed by cellulose acetate electrophoresis. ${\beta}-globulin$, A/G ratio and ${\beta}_2-globulin$ values were decreased in the calves with respiratory disease. Especially, ${\beta}_2-globulin$ were significantly decreased. In calves with diarrhea, there was no change in ${\beta}-globulin$ values. ${\beta}_2-globulin$ values were higher than that of the normal and respiratory diseased calves. 3. ${\alpha}-globulin$ values were increased in both of calves with diarrhea and respiratory disease. This tendency was due to increase ${\alpha}_2-globulin$ values. 4. The $\gamma$-globulin value of calves with diarrhea was the lowest among the 3 groups. 5. The total protein values of normal calves were $7.0{\pm}1.1g/dl$ and that of respiratory and diarrheal diseased calves were $6.9{\pm}0.9g/dl$ and $6.6{\pm}0.8g/dl$, respectively. Total protein value of calves with diarrhea was lower than that of normal and respiratory diseased calves. Globulin value of calves with diarrhea was the lowest among them. The low value of total protein in diarrheal diseased calves was due to decrease globulin values. 6. The fibrinogen values of calves with respiratory disease ($643{\pm}189mg/dl$) were significantly higher than that of normal calves($533{\pm}135mg/dl$) and calves with diarrhea($572{\pm}188mg/dl$). The plasma : fib. ratio of respiratory diseased calves was $12.0{\pm}4.9$, normal calves was $13.8{\pm}3.5$ and diarrheal diseased calves was $12.8{\pm}4.6$. The ratio of the calves with respiratory disease was significantly decreased.

• Parasites, Hosts and Diseases
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• v.45 no.2 s.142
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• pp.133-137
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• 2007

For evaluation of the prevalence of Cryptosporidium sp. infection in diarrheic and non-diarrheic humans in Iran, fecal specimens from diarrheic (n = 129) and non-diarrheic humans (n = 271) were collected and examined for the presence of Cryptosporidium sp. oocysts. The presence of Cryptosporidium sp. oocysts was determined by Ziehl-Neelsen acid-fast staining. Humans were grouped according to their age as follows: younger than 15, 16-25, 26-35, 36-50, and over 51 years. The results showed that the overall prevalence of infection in all 400 samples was 10.8%, but the prevalence (25.6%) in diarrheic humans was higher than that (3.7%) in non-diarrheic humans. Oocysts of Cryptosporidium sp. were detected in the feces of 21.4%, 9.3%, 8.8%, 6.7% and 5.7% of different age groups, respectively. The intensity of oocysts was significantly higher in diarrheic humans than in non-diarrheic ones. There was a significant association between Cryptosporidium sp. infection and occurrence of diarrhea (P < 0.05). The results indicate that Cryptosporidium sp. infection is prevalent in diarrheic humans in Iran.

• Animal Bioscience
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• v.36 no.1
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• pp.119-131
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• 2023

Objective: This study was to assess the effects of different doses of an essential oil blend (EOB) on growth performance, diarrhea occurrence (DO), hematological and blood biochemical profile, intestinal morphometry, morphology and microbiology, relative weight and length of organs, digestive content pH, and liver antioxidant status in weaning piglets. Methods: A total of 135 barrows (7.09±0.29 kg body weight) were allotted randomly in a randomized complete block design based on body weight with nine replications and three animals per pen. Dietary treatments were a negative control (NC): basal diet; positive control (PC): NC plus 125 mg performance-enhancing antibiotic (enramycin 8%)/kg diet; NC plus 100 mg EOB/kg diet (EO100); NC plus 200 mg EOB/kg diet (EO200); and NC plus 400 mg EOB/kg diet (EO400). Diarrhea occurrence was monitored daily, and performance at the end of each phase. Results: Gain to feed ratio was greater (p<0.05) in starter II pigs fed EO400 and EO200 than in those fed EO100. Pigs fed EO400 had lower (p<0.05) DO than those fed NC and EO100 in the total period. Pre-starter II pigs fed NC had (p<0.05) lower serum total protein and plasma protein than pigs fed PC. Pigs fed EO100 showed smaller (p<0.05) mean corpuscular volume (MCV) than pigs fed EO400. Starter II pigs fed EO400 had (p<0.05) greater MCV and lower mean corpuscular hemoglobin and erythrocytes than those fed EO100. There was a greater concentration (p<0.05) of band cells for PC, similar to EO400 and EO200. Performance-enhancing antibiotic and EOB to diets increased (p<0.05) liver superoxide dismutase activity. Conclusion: Adding 200 and 400 mg EOB/kg diet decreased DO and was advantageous to hematological and blood biochemical profile and liver antioxidant status without being detrimental to growth performance and gastrointestinal health in nursery pigs.