• 제목/요약/키워드: Diagnostic ability

검색결과 321건 처리시간 0.028초

An original device for train bogie energy harvesting: a real application scenario

  • Amoroso, Francesco;Pecora, Rosario;Ciminello, Monica;Concilio, Antonio
    • Smart Structures and Systems
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    • 제16권3호
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    • pp.383-399
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    • 2015
  • Today, as railways increase their capacity and speeds, it is more important than ever to be completely aware of the state of vehicles fleet's condition to ensure the highest quality and safety standards, as well as being able to maintain the costs as low as possible. Operation of a modern, dynamic and efficient railway demands a real time, accurate and reliable evaluation of the infrastructure assets, including signal networks and diagnostic systems able to acquire functional parameters. In the conventional system, measurement data are reliably collected using coaxial wires for communication between sensors and the repository. As sensors grow in size, the cost of the monitoring system can grow. Recently, auto-powered wireless sensor has been considered as an alternative tool for economical and accurate realization of structural health monitoring system, being provided by the following essential features: on-board micro-processor, sensing capability, wireless communication, auto-powered battery, and low cost. In this work, an original harvester device is designed to supply wireless sensor system battery using train bogie energy. Piezoelectric materials have in here considered due to their established ability to directly convert applied strain energy into usable electric energy and their relatively simple modelling into an integrated system. The mechanical and electrical properties of the system are studied according to the project specifications. The numerical formulation is implemented with in-house code using commercial software tool and then experimentally validated through a proof of concept setup using an excitation signal by a real application scenario.

UNG 기반 direct polymerase chain reaction (udPCR)을 이용한 돼지 써코바이러스 2형 진단법 (UNG-based direct polymerase chain reaction (udPCR) for the detection of porcine circovirus 2 (PCV2))

  • 김은미;박최규
    • 한국동물위생학회지
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    • 제37권4호
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    • pp.253-261
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    • 2014
  • Porcine circovirus disease (PCVD) is a major problem of swine industry worldwide, and diagnosis of PCV2, causal agent of PCVD, has been doing in clinical laboratories of pig disease by polymerase chain reaction (PCR) methods. But the PCR analyses have a serious problem of misdiagnosis by contamination of DNA, in particular, from carryover contamination with previously amplified DNA or extracted DNA from field samples. In this study, an uracil DNA glycosylase (UNG)-based direct PCR (udPCR) without DNA extraction process and DNA carryover contamination was developed and evaluated on PCV2 culture and field pig samples. The sensitivity of the udPCR combined with dPCR and uPCR was same or better than that of the commercial PCR (cPCR) kit (Median diagnostics, Korea) on PCV2-positive serum, lymph node and lung samples of the pigs. In addition, the udPCR method confirmed to have a preventing ability of mis-amplification by contamination of pre-amplified PCV2 DNA from previous udPCR. In clinical application, 170 pig samples (86 tissues and 84 serum) were analysed by cPCR kit and resulted in 37% (63/170) of positive reaction, while the udPCR was able to detect the PCV2 DNA in 45.3% (77/170) with higher sensitivity than cPCR. In conclusion, the udPCR developed in the study is a time, labor and cost saving method for the detection of PCV2 and providing a preventing effect for DNA carryover contamination that can occurred in PCR process. Therefore, the udPCR assay could be an useful alternative method for the diagnosis of PCV2 in the swine disease diagnostic laboratories.

CT 검사에서 조영제의 혈관외유출 예방을 위한 EDA 시스템 개발의 예비 보고 (The Development of Extravasation Detection Accessory System for the Preventive Contrast Media Extravasation in the Computed Tomography: A Preliminary Report)

  • 권대철;정석희;김태형;김정구;박범
    • 한국의학물리학회지:의학물리
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    • 제17권1호
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    • pp.32-39
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    • 2006
  • CT 검사에서 조영제의 혈관외유출을 예방하기 위해 EDA시스템을 증폭기, ADC, 스트레인 게이지로 구성하여 개발하였고, 스트레인 게이지의 신호의 수치를 나타내도록 프로그램을 설계하였다. 신호비율은 500/1000 sec, 분해능 값은 0에서 4,096범위로 표시하고, 입력범위 $0{\sim}5$ V이다. 혈관외유출 검출 문턱 값은 50으로 하였고, 10 간격으로 조정하도록 하였다. 개발된 EDA 시스템을 성인 50명을 대상으로 적용하였다. 2명의 환자에서 혈관외유출이 검출되었고, 조영제 주입속도는 2.0 mL/sec, 2.5 mL/sec, 압력은 137 psi, 158 psi, 혈관외유출된 조영제 용량은 22 mL, 25 mL였다. 설정된 주입 조영제에 비해 20% 정도의 적은 용량이 혈관외유출되었다. 개발된 EDA 시스템은 소량의 조영제를 검출하여 혈관외유출을 예방하는 효과가 있다.

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신생아에서 관찰할 수 있는 청성반응 (Auditory responses in neonates; a preliminary report)

  • 황순재;노관택
    • 대한기관식도과학회:학술대회논문집
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    • 대한기관식도과학회 1977년도 제11차 학술대회연제 순서 및 초록
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    • pp.4.1-4
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    • 1977
  • 신생아 및 유아에서의 청력의 진단에 지금까지 수많은 방법이 연구 발표되어 왔으며, 그 중에서도 소리에 대한 신생아, 및 유아의 구체적인 반응을 평가하는 것은 매우 중요하다. 저자들은 1977년 1월부터 동년 4월까지 서울대학교 소아과신생아실에 입원한 100명(남아 54명, 여아 46명)을 대상으로 하여 beltone audiometer model 10d(Ansi 1969)를 사용해서 피검자로 부터 4인치의 거리에서 3,000 Hz, 90dB의 순음으로 2초동안 자극하여 신생아에서 나타나는 반응을 조사하여 다음과 같은 결론을 얻었다. 1. 피검아의 연령은 2시간 내지 3.5시간이었으며(평균연령 2.4시간), 안검반사가 39%, (안검을 폐쇄시키는 반응이 10%, 안검을 개대시키는 반응이 29%), Moro refbex가 35%로 가장 많았으며, 그 외에 손가락을 빠는 반응이 14%, 동작을 갑자기 정지하는 반응이 6%, 머리를 소리자극의 방향으로 움직이는 반응이 2%, 아무 반응도 나타나지 않는 례가 4%의 순서였다. 2. 소리자극에 대한 신생아의 반응시간은 2초 내지 5초(평균 3.3초)이었다.

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Diagnostic accuracy of a combination of salivary hemoglobin levels, self-report questionnaires, and age in periodontitis screening

  • Maeng, You-Jin;Kim, Bo-Ra;Jung, Hoi-In;Jung, Ui-Won;Kim, Hee Eun;Kim, Baek-Il
    • Journal of Periodontal and Implant Science
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    • 제46권1호
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    • pp.10-21
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    • 2016
  • Purpose: This study evaluated the predictive performance of a combination of self-report questionnaires, salivary hemoglobin levels, and age as a non-invasive screening method for periodontitis. Methods: The periodontitis status of 202 adults was examined using salivary hemoglobin levels, responses to 10 questions on a self-report questionnaire, and the Community Periodontal Index (CPI). The ability of those two variables and the combination thereof with age to predict the presence of CPI scores of 3-4 and 4 was assessed using logistic regression and receiver operating characteristic (ROC) curve analysis. Results: CPI scores of 3-4 and 4 were present among 79.7% and 46.5% of the sample, respectively. The area under the ROC curves (AUROCs) of salivary hemoglobin levels for predicting prevalence of CPI scores of 3-4 and 4 were 0.63 and 0.67, respectively (with sensitivity values of 71% and 60% and specificity values of 56% and 72%, respectively). Two distinct sets of five questions were associated with CPI scores of 3-4 and 4, with AUROCs of 0.73 and 0.71, sensitivity values of 76% and 66%, and specificity values of 63% and 69%. The combined model incorporating both variables and age showed the best predictive performance, with AUROCs of 0.78 and 0.76, sensitivity values of 71% and 65%, and specificity values of 68% and 77% for CPI scores of 3-4 and 4, respectively. Conclusions: The combination of salivary hemoglobin levels and self-report questionnaires was shown to be a valuable screening method for detecting periodontitis.

화학기상증착 진공공정의 실시간 진단연구 (The Study on In-situ Diagnosis of Chemical Vapor Deposition Processes)

  • 전기문;신재수;임성규;박상현;강병구;윤진욱;윤주영;신용현;강상우
    • 한국진공학회지
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    • 제20권2호
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    • pp.86-92
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    • 2011
  • 본 연구에서는 새롭게 개발된 센서인 in-situ particle monitor (ISPM)와 기존센서의 기능을 업그레이드 한 센서인 self-plasma optical emission spectroscopy (SPOES)를 이용해 화학기상증착 진공공정을 진단하였다. 본 연구에서 사용된 증착공정 장비는 silane 가스를 이용한 silicon plasma enhanced chemical vapor deposition과 borophosphosilicate glass 증착장비이다. 두 장비의 증착 또는 클리닝 조건에서의 배출되는 오염입자와 배기가스를 개발된 센서를 이용해 공정상태를 실시간으로 진단하는 것과 개발된 센서의 센싱 능력을 검증하고자 하는 목적으로 연구가 진행되었다. 개발된 센서는 장비 배기구 설치되었으며, 공정압력, 유량, 플라즈마 파워 등의 공정변수 변화에 따른 오염입자 크기 및 분포와 배기 부산물의 변화를 측정하고, 측정 결과의 상호 연관성을 분석하였다.

내고장성 디지털 조속기의 신뢰도 평가 및 개발에 관한 연구 (A Study on Reliability Analysis and Development of Fault Tolerant Digital Governor)

  • 신명철;전일영;안병원;이성근;김윤식;진강규
    • 한국정보통신학회:학술대회논문집
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    • 한국해양정보통신학회 1999년도 추계종합학술대회
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    • pp.467-474
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    • 1999
  • 본 논문에서는 제어 시스템의 신뢰도를 높이고 중단없는 제어 동작을 실현하기 위하여 제어기를 삼중화한 내고장성 디지털 조속기를 설계하였으며, 이 시스템을 Markov process로 모델링하여 신뢰도를 해석하였다. 임무시간에서 삼중화 시스템은 단일 제어기 시스템에 비해 신뢰도 86[%]수준에서 약 1.8 배, 95[%]수준에서 약 2.8배, 99[%]수준에서 약 6배 증가함을 확인하였다. 또한 북제주 화력 발전소의 터빈 속도제어 시스템을 대상으로 디지털 속도제어 시스템을 설계하였으며, 설계된 디지털 속도제어 시스템의 유효성을 입증하기 위해 모의실험을 행하였다.

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학습자 트레이싱을 통한 원격 교육용 자가 진단 모듈 개발 (The Development of On-line Self-Test Module using Tracing Method)

  • 이규수;손철수;박홍준;심현;오재철
    • 정보처리학회논문지A
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    • 제19A권3호
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    • pp.147-154
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    • 2012
  • 창의력이나 문제해결력과 같은 고차원적인 사고 능력은 주어진 문제의 정 오답만으로는 진단이 어려우며, 진단을 위해서는 교수자가 학습자의 문제 해결 과정을 지켜보거나 해결 과정에 대한 학습자의 보고 과정이 요구된다. 더구나 교수자의 학습자에 대한 관찰이 불가능한 온라인 학습이나 버추얼 클래스와 같은 환경에서는 학습자의 문제 해결 과정을 평가하거나 학습자 스스로 자신의 부족한 부분을 진단하는 것은 더욱 어려워진다. 이러한 문제를 해결하는 최선의 방법은 학습자가 문제를 해결하는 동안을 추적하여 그 과정을 보고해 주는 것이라 할 수 있다. 본 연구에서는 MS 오피스군의 소프트웨어를 활용하여 주어진 문제를 해결하는 동안 학습자의 작업 내역을 트레이싱하여 최종적으로 학습자에게 자신의 부족한 부분을 진단해 주고 자신의 능숙도와 소프트웨어를 응용하여 주어진 문제를 해결하는 과정에 대한 평가를 해주는 모듈을 개발하였으며, 본 진단 모듈의 효용성 평가를 위하여 실제 MOS 시험을 준비하는 학습자 81명에 대한 적용 및 만족도 조사를 통하여 통계적으로도 유의미한 효과가 있음을 확인하였다.

개심술시 체외순환이 신장기능에 미치는 영향 (Effect of the Extracorporeal Circulation on Renal Function in Adult Open Heart Patients)

  • 이재원;서경필
    • Journal of Chest Surgery
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    • 제18권4호
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    • pp.718-731
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    • 1985
  • Renal dysfunction is a common complication of open-heart surgery: a form of controlled hemorrhagic shock, and successful perioperative management of renal dysfunction depends on recognition of the risk factors and optimal management of factors influencing renal function, including cardiopulmonary bypass, and early detection of renal failure. Changes in renal functional parameters including Ccr, Cosm, CH2O, FENa, and RFI were observed prospectively in forty five patients operated on at Dept. of Thoracic and Cardiovascular Surgery, S.N.U.H., from April to June, 1985. They were 23 males and 22 females with 35 acquired and 10 congenital heart diseases and the mean age and body surface area of them were 38.010.3 years [22-63] and 1.5518 M2[1.151.92] respectively. Followings are the conclusion. 1. The Ccr, representative of renal function, is significantly improved from 90.231.3 ml/min/M2 preoperatively to 101.536.4 ml/min/M2 postoperative and day [P<0.05], and all patients were classified as postoperative renal functional class I of Abel, which representing adequate renal protection during our cardiopulmonary bypass. 2. The Cosm is significantly elevated at immediate postperfusion time and remained high at postoperative one day representing osmotic diuresis at that time, but CH2O shows no significant changes at immediate postperfusion period and is decreased significantly at postoperative one day, representing recovery of renal concentrating ability at that time with decreasing urine flow. 3. The absolute value and changing tendency in FENa and RFI during perioperative period shows no diagnostic reliability on these parameters, but those of CH2O appear to reveal future renal function more accurately than Ccr 4. The depth of hypothermia may be protective upon renal function against the ill effects of prolonged nonpulsatile cardiopulmonary bypass. 5. The depth of the hypothermia, pump time of more than 150 minutes, poor cardiac function, and intraoperative events such as embolism appear to be related with immediate postperfusion renal function. 6. Hemoglobinuria and hemolysis, poor preoperative renal function, history of cardiac surgery, and massive transfusion associated with bleeding appear not to be related with renal dysfunction.

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Diagnostic Value of Early Inflammatory Reaction in Postoperative Infection of the Lumbar Spine

  • Mun, Ji-Hun;Kim, Dong-Hyun;Ryu, Kyeong-Sik;Park, Chun-Kun;Kim, Moon-Chan
    • Journal of Korean Neurosurgical Society
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    • 제38권3호
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    • pp.206-210
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    • 2005
  • Objective : Our aim is to evaluate the early changes of biologic markers such as white blood cell[WBC] count, erythrocyte sedimentation rate[ESR] and C-reactive protein[CRP] in early diagnosis of postoperative infection and to differentiate infection from inflammatory reaction in lumbar spine surgery. Methods : We reviewed 330patients who had undergone spinal operations between May 1999 and October 2001. For this study, the patients were classified into two groups, which include a group that underwent spinal decompressive surgery without instrumentation[SD], and the other group that underwent fusion surgery with spinal instrumentation[SI]. And each group was also subdivided into two groups respectively, one with infection and the other without infection. We retrospectively analyzed the WBC count, ESR and CRP preoperatively and postoperatively, according to their operation type and postoperative infection history. Results : Inflammatory indices were physiologically affected by instrumentation itself. But ESR and CRP elevations were more prolonged and sustained under infection. In SD patients without infection, ESR and CRP were stabilized 5 days after surgery. In SI patients without infection, CRP was stabilized about 7days after surgery, but ESR showed sustained and variously elevated. In both SD and SI groups, the stabilization of CRP was the most reliable behavior of surgery without infection. Conclusion : C-reactive protein is most sensitive parameter for postoperative spine infection. The knowledge of the inflammatory indices and their relatively uniform patterns with or without infection offers surgeons the ability to infer the state of surgical wound.