• Journal of The Korean Society of Inherited Metabolic disease
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• v.5 no.1
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• pp.108-115
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• 2005

Inherited metabolic diseases (IMD) comprise a large class of genetic diseases involving disorders of metabolism. The majorities are due to defects of single genes that code for enzymes that facilitate conversion of various substances into others. Because of the multiplicity of conditions, many different diagnostic tests are used for screening of IMD. Molecular genetic diagnosis is the detection of pathogenic mutations in DNA and/or RNA samples and is becoming a much more common practice in medicine today. The purpose of molecular genetic testing in IMD includes diagnostic testing, pre-symptomatic testing, carrier screening, prenatal diagnosis, preimplantation testing, and population screening. However, because of the complexity, difficulty in interpreting the result, and the ethical considerations, an understanding of technical, conceptual, and practical aspects of molecular genetic diagnosis is mandatory.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2013.10a
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• pp.459-462
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• 2013

CRDI 시스템에서의 ECU는 센서의 정보를 분석하여 최적의 조건으로 엔진이 동작하도록 한다. 이러한 ECU의 프로그램 부분과 데이터 부분은 제작자에서만 변경할 수 있어 엔진을 진단하는 진단기의 경우 전문가가 아니면 사용하거나 내용을 이해하기가 쉽지 않다. 본 연구에서는 산업용 차량의 엔진 데이터 값을 OBD-II표준을 사용하여 입력받아 사용자 중심의 진단기를 PC 및 모바일용으로 개발하였다. 본 연구의 진단기는 운전자 중심의 진단 서비스를 제공하며, 자동차 고장진단 신호 및 센서 출력 신호를 유선시스템과 무선 시스템인 블루투스 모듈을 이용하여 실시간 통신이 제공되도록 함으로써 엔진이상으로 인한 사고의 예방이 가능하고, 최적의 조건으로 엔진이 동작하므로 과도한 배기가스 배출이나 불완전 연소가스 배출과 같은 대기환경오염을 예방할 수 있어 최근 대두되고 있는 에코산업에도 이바지 할 수 있을 것이다.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2014.05a
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• pp.458-461
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• 2014

CRDI 시스템에서의 ECU는 센서의 정보를 분석하여 최적의 조건으로 엔진이 동작하도록 한다. 이러한 ECU의 프로그램 부분과 데이터 부분은 제작자에서만 변경할 수 있어 엔진을 진단하는 진단기의 경우 전문가가 아니면 사용하거나 내용을 이해하기가 쉽지 않다. 본 연구에서는 산업용 차량의 엔진 데이터 값을 OBD-II 표준을 사용하여 입력받아 사용자 중심의 진단기를 PC 및 모바일용으로 개발하였다. 본 연구의 진단기는 운전자 중심의 진단 서비스를 제공하며, 자동차 고장진단 신호 및 센서 출력 신호를 유선시스템과 무선 시스템인 블루투스 모듈을 이용하여 실시간 통신이 제공되도록 함으로써 엔진이상으로 인한 사고의 예방이 가능하고, 최적의 조건으로 엔진이 동작하므로 과도한 배기가스 배출이나 불완전 연소가스 배출과 같은 대기환경오염을 예방할 수 있어 최근 대두되고 있는 에코산업에도 이바지 할 수 있을 것이다.

• Journal of the Korean Society of Radiology
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• v.12 no.3
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• pp.289-295
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• 2018

Most diagnostic devices in the medical field use X-ray sources, which emit energy spectra. In radiological diagnosis, the quantitative and qualitative analyses of X-rays are essential for maintaining the image quality and minimizing the radiation dose to patients. This work aims to obtain the X-ray energy spectra used in diagnostic imaging by Monte Carlo simulation. Various X-ray spectra are simulated using a Monte Carlo simulation tool. These spectra are then compared to the reference data obtained with a tungsten anode spectral model using the interpolating polynomial (TASMIP) code. The X-ray tube voltages used are 50, 60, 80, 100, and 110 kV, respectively. CdTe and a-Se detector are used as the detectors for obtaining the X-ray spectra. Simulation results demonstrate that the various X-ray spectra are well matched with the reference data. Based on the simulation results, an appropriate X-ray spectrum, in accordance with the tube voltage, can be selected when generating an image for diagnostic imaging. The dose to be delivered to the patient can be predicted prior to examination in the diagnostic field.

• Proceedings of the KIEE Conference
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• 2000.07c
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• pp.1903-1905
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• 2000

Power transformers have a tendency of ultra-high voltage capacity as power demand increases day after day KEPCO also will have plan to supply transmission power from 345KV to 765KV in the early of 2000. Therefore, the fault by insulation destruction gives rise to large area of power failure in huge capacity transformers. On-line predictive diagnostics is very important in power transformers because of economic loss and its spreading effect. This study presents the algorithm for transformer oil analysis used KEPCO code, IEC code, gas pattern method and Dornenburg & Roger Ratio method. We also describe the MMI display of expert system programmed by Element Expert Tool(Neuron Data Inc.).

• Journal of the Korea institute for structural maintenance and inspection
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• v.7 no.2
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• pp.219-229
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• 2003

The objective of this work is to verify the Code specified girder distribution factors for short and medium span bridges. To accomplish this objective, field tests were carried out on seventeen simply supported highway bridges. This paper presents the procedure and results of field tests that were performed to verify girder distribution factors. Finite Element analyses previously performed at the University of Michigan indicated that in most cases currently used girder distribution factors specified in AASHTO Codes are too conservative. However, these studies also showed that for short spans and short girder spacings, the girder distribution factors can be too permissive. Therefore, this paper focused on experimental evaluation of girder distribution factors for short and medium span steel girder bridges. The results were compared with the distribution factors specified by AASHTO Standard (2000) and AASHTO LRFD Code (1998). It has been found that the measured girder distribution factors are lower than AASHTO values in most cases, and sometimes the code specified values are overly conservative. The research work involved formulation of the testing procedure, selection of structure, installation of equipment, measurements, and interpretation of the results.

• Nuclear Engineering and Technology
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• v.50 no.8
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• pp.1306-1313
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• 2018

The randomness and incipient nature of certain faults in reactor systems warrant a robust and dynamic detection mechanism. Existing models and methods for fault diagnosis using different mathematical/statistical inferences lack incipient and novel faults detection capability. To this end, we propose a fault diagnosis method that utilizes the flexibility of data-driven Support Vector Machine (SVM) for component-level fault diagnosis. The technique integrates separately-built, separately-trained, specialized SVM modules capable of component-level fault diagnosis into a coherent intelligent system, with each SVM module monitoring sub-units of the reactor coolant system. To evaluate the model, marginal faults selected from the failure mode and effect analysis (FMEA) are simulated in the steam generator and pressure boundary of the Chinese CNP300 PWR (Qinshan I NPP) reactor coolant system, using a best-estimate thermal-hydraulic code, RELAP5/SCDAP Mod4.0. Multiclass SVM model is trained with component level parameters that represent the steady state and selected faults in the components. For optimization purposes, we considered and compared the performances of different multiclass models in MATLAB, using different coding matrices, as well as different kernel functions on the representative data derived from the simulation of Qinshan I NPP. An optimum predictive model - the Error Correcting Output Code (ECOC) with TenaryComplete coding matrix - was obtained from experiments, and utilized to diagnose the incipient faults. Some of the important diagnostic results and heuristic model evaluation methods are presented in this paper.

• Nuclear Engineering and Technology
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• v.55 no.4
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• pp.1265-1268
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• 2023

One important issue in using radiopharmaceuticals as therapeutic and imaging agents is predicting different organ absorbed dose following their injection. The present study aims at extrapolating dosimetry estimates to a female phantom from the animal data of ⁸⁹Zr radionuclide accumulation using the Sparks-Idogan relationship. The absorbed dose of ⁸⁹Zr radionuclide in different organs of the human body was calculated based on its distribution data in mice using both MIRD method and the MCNP simulation code. In this study, breasts, liver, heart wall, stomach, kidneys, lungs and spleen were considered as source and target organs. The highest and the lowest absorbed doses were respectively delivered to the liver (4.00E-02 and 3.43E-02 mGy/MBq) and the stomach (1.83E-03 and 1.66E-03 mGy/MBq). Moreover, there was a good agreement between the results obtained from both MIRD and MCNP methods. Therefore, according to the dosimetry results, [⁸⁹Zr] DFO-CR011-PET/CT seems to be a suitable for diagnostic imaging of the breast anomalies for CDX-011 targeting gpNMB in patients with TNBC in the future.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.15 no.11
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• pp.2347-2352
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• 2011

driver for safety always check the status of their vehicle, and it is essential to understand. But if you want to know the status of the driver of the vehicle in specialist referral time and money because it costs the operator shall be paid.IT technoligy with the development of the various features of your phone to check the status of the vehicle was able to do. However, the car' existing phone system, car diagnostic expertise must be learned because it will reveal the status of the vehicle do not have the expertise to not highlight the need for diagnostic. To reflect these points in smartphone users to easily use their own vehicles at a time to determine the status of a system that is required. In this paper, OBD-II protocol conversion WiFi OBD-II connector, retrieving information from the driver of the vehicle replacement cycle of consumables required vehicle inspection, vehicle problems in real-time diagnostic information to the user ease of use shows the iPhone implementation in the automotive supply was implemented based on the smartphone.

• Nuclear Engineering and Technology
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• v.54 no.9
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• pp.3317-3323
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• 2022

Half Value Layer calculations theoretically need prior specification of linear attenuation calculations, since the HVL value is derived by dividing ln(2) by the linear attenuation coefficient. The purpose of this study was to establish a direct computational model for determining HVL, a vital parameter in nuclear radiation safety studies and shielding material design. Accordingly, a typical gamma-ray transmission setup has been modeled using MCNPX (version 2.4.0) general-purpose Monte Carlo code. The MCNPX code's INPUT file was designed with two detection locations for primary and secondary gamma-rays, as well as attenuator material between those detectors. Next, Half Value Layer values of some well-known gamma-ray shielding materials such as lead and ordinary concrete have been calculated throughout a broad gamma-ray energy range. The outcomes were then compared to data from the National Institute of Standards and Technology. The Half Value Layer values obtained from MCNPX were reported to be highly compatible with the HVL values obtained from the NIST standard database. Our results indicate that the developed INPUT file may be utilized for direct computations of Half Value Layer values for nuclear safety assessments as well as medical radiation applications. In conclusion, advanced simulation methods such as the Monte Carlo code are very powerful and useful instruments that should be considered for daily radiation safety measures. The modeled MCNPX input file will be provided to the scientific community upon reasonable request.