• 조명전기설비학회논문지
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• 제29권8호
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• pp.98-103
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• 2015

Power plant is that very high reliability when industrial and economic impact on the overall electric power system is required, it is essential to improve the reliability, especially the fault prediction diagnosis. Since an accident caused by the partial discharge in the power plant is above state has a faster response characteristic than the other indications in the case of any, the partial discharge generated in the power plant immediately detect the deterioration of insulation due to the accident of the power plant and the non-drawn It should prevent or reduce. Partial Discharge Measuring Systems for UHV SF6 Gas Insulated Switchgear and power transformer on site installed has some probability of abnormal recognition in case of non-flexible deal with on site noise. Many methode to eliminate these kinds of noises, UHF Detection System is chosen as purchase description in Korea, but this system having a bandwidth between 500MHz 1.5GHz wide band. Initial install periods(about 20 years ago), this band had no strong signal source, but in these days this wide band have strong signals, such as LTE. So, module described in this paper is designed as simultaneously use with wide and narrow band for solve this noise problem, and introduce this system.

• Journal of Genetic Medicine
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• 제17권1호
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• pp.39-42
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• 2020

The Senior-Loken syndrome was first described in 1961 as an oculo-renal disease consisting of familial juvenile nephronophthisis and Leber congenital amaurosis. It is a rare autosomal recessive disorder with a prevalence of 1:1,000,000 caused by mutations in nine genes (NPHP 1-8 and NPHP 10). Ocular manifestations (e.g., photophobia, nystagmus, and extreme hyperopia) occur within the first few years of life while renal manifestations (e.g., formation of multiple cysts impairing kidney function and end-stage renal disease) appear in late childhood to adolescence. Here, we report a case of a Filipino male presenting with rotatory nystagmus and progressive deterioration of vision since childhood. He had congenital amaurosis and juvenile nephronophthisis that progressed to end stage renal disease by age 19. All laboratory and imaging findings were consistent with chronic kidney disease. Molecular genetic testing of ciliopathy-related genes was performed revealing a homozygous mutation in exon 11 of the IQCB1/NPHP5 gene, c.1090C>T (p.Arg364^⁎). This sequence change created a premature translational stop signal resulting in a truncated protein product, nephrocystin-5 and its consequent loss of function. His symptoms eventually improved with initiation dialysis. The prognosis of Senior-Loken syndrome remains dismal and a high index of suspicion, early diagnosis and timely intervention of renal complications are warranted.

• Journal of Korean Neurosurgical Society
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• 제61권6호
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• pp.767-773
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• 2018

Three male patients diagnosed with surfer's myelopathy (19-30 years) were admitted to our hospital. All three patients were novice surfers showing a typical clinical course of rapid progression of paraplegia following the onset of back pain. Typical history and magnetic resonance imaging features indicated the diagnosis of surfer's myelopathy. Two patients received high-dose steroid therapy and the other was treated with induced hypertension. One patient treated with induced hypertension showed almost full recovery; however, two patients who received high-dose steroid therapy remained completely paraplegic and required catheterization for bladder and bowel dysfunction despite months of rehabilitation. Our case series demonstrates the potentially devastating neurological outcome of surfer's myelopathy; however, early recovery in the initial 24-72 hours of presentation can occur in some patients, which is in accordance with previous reports. Ischemic insult to the spinal cord is thought to play a crucial role in the pathophysiology of surfer's myelopathy. Treatment recommendations include hydration, induced hypertension, early spinal angiography with intra-arterial intervention, intravenous tissue plasminogen activator, and high-dose steroid therapy; however, there is no standardized treatment option available. Early recovery appears to be important for long-term neurological outcome. Induced hypertension for initial treatment can be helpful for improving spinal cord perfusion; therefore, it is important for early and long-term neurological recovery. Education and awareness are essential for preventing surfer's myelopathy and avoiding further deterioration of neurological function.

• Journal of Dental Anesthesia and Pain Medicine
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• 제17권4호
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• pp.271-280
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• 2017

Background: The number of patients with Alzheimer's disease is growing worldwide, and the proportion of patients requiring dental treatment under general anesthesia increases with increasing severity of the disease. However, outpatient anesthesia management for these patients involves great risks, as most patients with Alzheimer's disease are old and may show reduced cardiopulmonary functions and have cognitive disorders. Methods: This study retrospectively investigated 43 patients with Alzheimer's disease who received outpatient anesthesia for dental treatment between 2012-2017. Pre-anesthesia patient evaluation, dental treatment details, anesthetics dose, blood pressure, duration and procedure of anesthesia, and post-recovery management were analyzed and compared between patients who underwent general anesthesia or intravenous sedation. Results: Mean age of patients was about 70 years; mean duration of Alzheimer's disease since diagnosis was 6.3 years. Severity was assessed using the global deterioration scale; 62.8% of patients were in level ${\geq}6$. Mean duration of anesthesia was 178 minutes for general anesthesia and 85 minutes for intravenous sedation. Mean recovery time was 65 minutes. Eleven patients underwent intravenous sedation using propofol, and 22/32 cases involved total intravenous anesthesia using propofol and remifentanil. Anesthesia was maintained with desflurane for other patients. While maintaining anesthesia, inotropic and atropine were used for eight and four patients, respectively. No patient developed postoperative delirium. All patients were discharged without complications. Conclusion: With appropriate anesthetic management, outpatient anesthesia was successfully performed without complications for dental treatment for patients with severe Alzheimer's disease.

• 대한한방내과학회지
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• 제42권5호
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• pp.1082-1093
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• 2021

Objective: Alzheimer's disease is characterized by progressive, irreversible brain damage and cognitive decline. Although the diagnosis and treatment of the prodromal symptoms of dementia are important, no treatment for mild cognitive impairment has been currently established. Herein, we report the case of an 80-year-old female patient with memory complaints treated with Gugijihwang-tang, a traditional Korean medicine herbal formula, as an add-on medication. Case Presentation: The patient was diagnosed with mild cognitive impairment based on clinical examinations using the Mini-Mental State Examination (MMSE), the Consortium to Establish a Registry for Alzheimer's Disease (CERAD), Activities of Daily Living (ADL) Scale, Global Deterioration (GDR) Scale, and Clinical Dementia Rating (CDR) Scale. She was treated with Gugijihwang-tang bis in die for 12 months while continuing her original medications, including 5-mg donepezil and 590-mg acetyl-l-carnitine. The MMSE score in the Korean Version of the CERAD Assessment Packet increased from 21 to 27 during the 12-month treatment period, and the CERAD 2 score increased from 33 to 62. The instrumental ADL scale score improved from 11 to 5. Other clinical examination results also showed improvement. The patient was satisfied and experienced no significant adverse events related to the Gugijihwang-tang treatment. Conclusion: This case suggests that Gugijihwang-tang could be considered as a treatment method for patients with mild cognitive impairment.

• 대한치매학회지
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• 제17권4호
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• pp.163-173
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• 2018

Background and Purpose: Behavioral variant frontotemporal dementia (bvFTD) is a subtype of frontotemporal dementia, which has clinical symptoms of progressive personality and behavioral changes with deterioration of social cognition and executive functions. The pathology of bvFTD is known to be tauopathy or TDP-43 equally. We analyzed the $^{18}F-THK5351$ positron emission tomography (PET) scans, which were recently developed tau PET, in patients with clinically-diagnosed bvFTD. Methods: Forty-eight participants, including participants with behavioral variant frontotemporal dementia (bvFTD, n=3), Alzheimer's disease (AD, n=21) and normal cognition (NC, n=24) who completed 3T magnetic resonance images, $^{18}F-THK5351$ PET scans, and detailed neuropsychological tests were included in the study. Voxel-wise statistical analysis and region of interest (ROI)-based analyses were performed to evaluate the retention of THK in bvFTD patients. Results: In the voxel-based and ROI-based analyses, patients with bvFTD showed greater THK retention in the prefrontal, medial frontal, orbitofrontal, anterior cingulate, insula, anterior inferior temporal and striatum regions compared to NC participants. Left-right asymmetry was noted in the bvFTD patients. A patient with extrapyramidal symptoms showed much greater THK retention in the brainstem. Conclusions: The distribution of THK retention in the bvFTD patients was mainly in the frontal, insula, anterior temporal, and striatum regions which are known to be the brain regions corresponding to the clinical symptoms of bvFTD. Our study suggests that $^{18}F-THK5351$ PET imaging could be a supportive tool for diagnosis of bvFTD.

• 자원환경지질
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• 제54권3호
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• pp.311-330
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• 2021

청송 신성리 공룡발자국 화석지에는 최소한 수각류 보행렬 11개, 용각류 보행렬 3개 및 조각류 보행렬 1개 이상 존재하여, 국내 다른 공룡발자국 화석지에 비해 수각류 보행렬의 밀집도가 높다. 공룡발자국의 모암은 미사암과 이암의 암상을 보이나 전체적으로 열변질을 받아 혼펠스화되어 있다. 이 화석지의 표면에는 다양한 방향의 절리가 나타나며 미세균열과 박락을 제외하면 모든 손상요인에서 낮은 점유율을 보였다. 초음파 속도 측정 결과, 화석지의 암석은 비교적 건전한 물성을 보여 안정적인 것으로 평가되었다. 공룡발자국 화석의 손상형태에 따라 보존처리 유형을 세분하면, 균열의 진전을 제어할 수 있는 강화처리가 필요한 발자국화석이 절반 이상의 비율을 보였다. 또한 발자국의 가시화를 위해 도포한 흰색 페인트가 열화되면서 암편 탈락을 유발하여 오히려 화석의 손상을 촉진하는 것으로 나타나, 이를 대체할 방안이 검토되어야 할 것이다.

• 한국전산구조공학회논문집
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• 제34권4호
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• pp.183-189
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• 2021

구조물에 장기적으로 발생하는 노후화를 정량적으로 파악하기 위해 상시진동 데이터를 활용한 일반화된 모니터링 시스템에 관한 연구가 세계적으로 활발히 수행중이다. 본 연구에서는 구조물에서 장기적으로 취득되는 동특성을 앙상블 학습에 활용하여 구조물의 이상을 감지하기 위한 보급형 엣지 컴퓨팅 시스템을 구축하였다. 시스템의 하드웨어는 라즈베리파이와 보급형 가속도계, 기울기센서, GPS RTK 모듈, 로라 모듈로 구성됐다. 실험실 규모의 구조물 모형 진동실험을 통해 동특성을 활용한 앙상블 학습의 구조물 이상감지를 검증하였으며, 실험을 기반으로 한 실시간 동특성 추출 분산처리 알고리즘을 라즈베리파이에 탑재하였다. 구축된 시스템을 하우징하고 포항시 행정복지센터에 설치하여 데이터를 취득함으로써 개발된 시스템의 현장 적용성을 검증하였다.

• International Journal of Computer Science & Network Security
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• 제24권5호
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• pp.53-63
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• 2024

Alzheimer's disease is a brain disorder that worsens over time and affects millions of people around the world. It leads to a gradual deterioration in memory, thinking ability, and behavioral and social skills until the person loses his ability to adapt to society. Technological progress in medical imaging and the use of artificial intelligence, has provided the possibility of detecting Alzheimer's disease through medical images such as magnetic resonance imaging (MRI). However, Deep learning algorithms, especially convolutional neural networks (CNNs), have shown great success in analyzing medical images for disease diagnosis and classification. Where CNNs can recognize patterns and objects from images, which makes them ideally suited for this study. In this paper, we proposed to compare the performances of Alzheimer's disease detection by using two deep learning methods: You Only Look Once (YOLO), a CNN-enabled object recognition algorithm, and Visual Geometry Group (VGG16) which is a type of deep convolutional neural network primarily used for image classification. We will compare our results using these modern models Instead of using CNN only like the previous research. In addition, the results showed different levels of accuracy for the various versions of YOLO and the VGG16 model. YOLO v5 reached 56.4% accuracy at 50 epochs and 61.5% accuracy at 100 epochs. YOLO v8, which is for classification, reached 84% accuracy overall at 100 epochs. YOLO v9, which is for object detection overall accuracy of 84.6%. The VGG16 model reached 99% accuracy for training after 25 epochs but only 78% accuracy for testing. Hence, the best model overall is YOLO v9, with the highest overall accuracy of 86.1%.

• 대한토목학회논문집
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• 제35권1호
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• pp.203-215
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• 2015

본 연구는 농촌지역의 쇠퇴도를 진단하고, 농촌생활권의 기초단위인 읍 면 지역에 대한 공간적 쇠퇴 특성과 유형을 도출하는데 목적을 두고 있다. 이를 위해, 충청권 27개 시 군을 대상으로 거시적 차원의 쇠퇴수준과 잠재수준을 분석하여 도시차원의 쇠퇴현상을 진단한다. 다음으로 공간단위를 세분화하여 충청권의 274개 읍 면지역을 대상으로 쇠퇴수준을 분석하고, K-평균군집분석을 적용하여 쇠퇴유형 및 쇠퇴특성을 도출한다. 충청권 시 군 별 쇠퇴수준 및 잠재수준 분석결과, 충남지역의 청양군, 서천군, 태안군이 높은 쇠퇴도를 보이고 있으며, 충북지역의 전통적 낙후지역인 남부 3군(보은, 옥천, 영동)과 단양군, 괴산군의 쇠퇴도가 높게 나타나고 있다. 또한, 충청권의 읍 면지역 중 쇠퇴의 경향을 보이는 166개 읍 면지역에 대한 군집분석 결과 인구 및 주택 노후화지역(29), 경제기반 취약지역(16), 중심지접근성 취약지역(42), 주거환경 열악지역(51), 노령인구 취약지역(28)의 5개 군집유형의 쇠퇴특성이 도출되었다. 충청권 농촌지역의 쇠퇴특성과 유형화를 시도한 본 연구는 농촌지역 활성화 정책 수립에 있어 기초자료로 활용될 것으로 기대되며, 향후 연구에서는 읍 면지역 차원을 넘어 농촌정체성의 기초단위가 되는 농촌마을을 대상으로 종합적인 진단과 맞춤형 정책발굴 연구가 이어질 것으로 기대된다.