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A Comparative Study of Deep Learning Techniques for Alzheimer's disease Detection in Medical Radiography

  • Received : 2024.05.05
  • Published : 2024.05.30

Abstract

Alzheimer's disease is a brain disorder that worsens over time and affects millions of people around the world. It leads to a gradual deterioration in memory, thinking ability, and behavioral and social skills until the person loses his ability to adapt to society. Technological progress in medical imaging and the use of artificial intelligence, has provided the possibility of detecting Alzheimer's disease through medical images such as magnetic resonance imaging (MRI). However, Deep learning algorithms, especially convolutional neural networks (CNNs), have shown great success in analyzing medical images for disease diagnosis and classification. Where CNNs can recognize patterns and objects from images, which makes them ideally suited for this study. In this paper, we proposed to compare the performances of Alzheimer's disease detection by using two deep learning methods: You Only Look Once (YOLO), a CNN-enabled object recognition algorithm, and Visual Geometry Group (VGG16) which is a type of deep convolutional neural network primarily used for image classification. We will compare our results using these modern models Instead of using CNN only like the previous research. In addition, the results showed different levels of accuracy for the various versions of YOLO and the VGG16 model. YOLO v5 reached 56.4% accuracy at 50 epochs and 61.5% accuracy at 100 epochs. YOLO v8, which is for classification, reached 84% accuracy overall at 100 epochs. YOLO v9, which is for object detection overall accuracy of 84.6%. The VGG16 model reached 99% accuracy for training after 25 epochs but only 78% accuracy for testing. Hence, the best model overall is YOLO v9, with the highest overall accuracy of 86.1%.

Keywords

Acknowledgement

We would like to express our sincere gratitude to Umm Al-Qura University for providing the necessary resources and environment for us to conduct this research.

References

  1. Kumar, A., Sidhu, J., Goyal, A., Tsao, J. W., & Doerr, C. (Eds.). (2022). Alzheimer Disease. StatPearls [National Institutes of Health (.gov)]. Retrieved May 14, 2024, from https://www.ncbi.nlm.nih.gov/books/NBK499922/
  2. Huang, Y., Cheng, S., Wang, Y., Sun, L., Liu, Y., & Zhang, Y. (2020, August 12). Early-Stage Alzheimer's Disease Prediction Using Machine Learning Models. National Institutes of Health (.gov). Retrieved May 14, 2024, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8927715/
  3. Tourist, "Alzheimer's Dataset (4 class of Images)," Kaggle, 2021. [Online]. Available: https://www.kaggle.com/datasets/tourist55/alzheimersdataset-4-class-of-images.
  4. Siuly, S., Zhang, Y. Medical Big Data: Neurological Diseases Diagnosis Through Medical Data Analysis. Data Sci. Eng. 1, 54-64 (2016). https://doi.org/10.1007/s41019-016-0011-3
  5. Saidani, T., Ghodhbani, R., Alhomoud, A., Alshammari, A., Zayani, H., & Ben Ammar, M. (2024). Hardware Acceleration for Object Detection using YOLOv5 Deep Learning Algorithm on Xilinx Zynq FPGA Platform. ETASR, DOI: https://doi.org/10.48084/etasr.6761.
  6. Tammina, S. (2019, October). Transfer learning using VGG-16 with Deep Convolutional Neural Network for Classifying Images. International Journal of Scientific and Research Publications (IJSRP), 9(10), 146-153. https://doi.org/10.29322/IJSRP.9.10.2019.p9420
  7. Roboflow. (2024), Jenan Mustafa. Accessed: Date (Apr 27). [Online]. Available: https://universe.roboflow.com/alzheimerkwn1w/alzheimer-6sust
  8. Sorour, S. E., El-Mageed, A. A. A., Albarrak, K. M., Alnaim, A. K., Wafa, A. A., & El-Shafeiy, E. (2024). Classification of Alzheimer's disease using MRI data based on Deep Learning Techniques. Journal of King Saud University - Computer and Information Sciences, 36(2). https://doi.org/10.1016/j.jksuci.2024.101940
  9. El-Assy, A. M., Amer, H. M., Ibrahim, H. M., & Mohamed, M. A. (2024). A novel CNN architecture for accurate early detection and classification of Alzheimer's disease using MRI data. Scientific Reports, 14(1). https://doi.org/10.1038/s41598-024-53733-6
  10. Aleid, A. Alhussaini, K. Alanazi, R. Altwaimi, M. Altwijri, O.& Saad, S.A. 2023. Artificial Intelligence Approach for Early Detection of Brain Tumors Using MRI Images. Applied sciences. https://doi.org/10.3390/app13063808
  11. Al Shehri, W.2022.Alzheimer's disease diagnosis and classification using deep learning techniques. PMC Journal. https://doi.org/10.7717/peerj-cs.1177
  12. Salehi, A., Baglat, P., Sharma, B., Upadhya, A., & Gupta, G. (2020). A CNN Model: Earlier Diagnosis and Classification of Alzheimer Disease using MRI. International Conference on Smart Electronics and Communication (ICOSEC). DOI: 10.1109/ICOSEC49089.2020.9215402
  13. Nawaz, A., Anwar, S. M., Liaqat, R., Iqbal, J., Bagci, U., & Majid, M. (2021). Deep Convolutional Neural Network based Classification of Alzheimer's Disease using MRI data. arXiv preprint arXiv:2101.02876.
  14. AbdulAzeem, Y., Bahgat, W., & Badawy, M. (2021). A CNN-based framework for classification of Alzheimer's disease. Neural Comput & Applic 33, 10415-10428. https://doi.org/10.1007/s00521-021-05799-w
  15. Ebrahim, D., Ali-Eldin, A.M.T., Moustafa, H.E., & Arafat, H. (2020). Alzheimer Disease Early Detection Using Convolutional Neural Networks. International Conference on Computer Engineering and Systems (ICCES). IEEE. DOI: 10.1109/ICCES51560.2020.9334594
  16. Patro, S., Nisha, V.M. (2019). [Title of the Research Paper]. International Journal of Engineering Research & Technology (IJERT), 8(05) .Retrieved from http://www.ijert.org/vol8/issue05/ . ISSN: 2278-0181.
  17. Sarraf, S., Tofighi, G. Classification of Alzheimer's Disease Structural MRI Data by Deep Learning Convolutional Neural Networks. (2017). arXiv preprint arXiv:1607.06583
  18. Jiang, P., Ergu, D., Liu, F., Cai, Y., & Ma, B. (2022). A Review of Yolo Algorithm Developments. ScienceDirect. Retrieved from https://doi.org/10.1016/j.procs.2022.01.135
  19. Cao, B., Jiang, A., Shen, J., & Liu, J. (2024). Research on Rapid Recognition of Moving Small Targets by Robotic Arms Based on Attention Mechanisms. MDPI. Retrieved from https://doi.org/10.3390/app14103975.
  20. Rajamohanan, R., & Latha, B. C. (2023). An Optimized YOLO v5 Model for Tomato Leaf Disease Classification with Field Dataset. Engineering, Technology & Applied Science Research, 13(6), 12033-12038. Retrieved from https://doi.org/10.48084/etasr.6377.