A novel glucanhydrolase(DXAMase) from a mutant of Lipomyces starkeyi(KSM 22) has been shown effective in hydrolysis of mutan, reduction of mutan formation by Streptococcus mutans and removal pre-formed sucrose-dependentadherent microbial film and DXAMase has been strongly bound to hydroxyapatitie. These in vitro properties of Lipomyces starkeyi DXAMase are desirable for its application as a dental plaque control agent. This study was performed to determine the adjunctive oral hygiene benefits and safety of dextranase(Lipomyces starkeyi KSM 22 DXAMase)-containing mouthwash when used alongside normal tooth-brushing. This 6-month clinical trial was placebo-controlled double-blind design evaluating 1U/ml dextranase mouthwash and 0.12% chlorhexidine mouthwash. A total 39 systemically healthy subjects, who had moderate levels of plaque and gingivitis were included. At baseline, 1, 3 and 6 months, subjects were scored for plaque accumulation(Turesky modification of Quingley-Hein's plaque index), gingivitis status($L\ddot{o}e$ and Silness gingival index), and tooth stain(Area and severity index system by Lang et al). Additionally, oral mucosal examinations were performed and subjects questioned for adverse symptoms. Two weeks after pre-experiment examinations and a professional prophylaxis, the subjects provided with allocated mousewash and instructed to use 20-ml volumes for 30s twice daily after toothbrushing. All the groups showed significant increase in plaque accumulation since 1 month of experiment. During 6 months' period, the Dextranase mouthwash group showed the least increase in plaque accumulation, compared to the Chlorhexidine mouthwash and placebo groups. As for gingival inflammation, all the groups showed significant increase during 6 months of experiment. The Experimental group(Dextranase mouthwash) also showed the least increase in gingival index score, compared to the Positive control(Chlorhexidine mouthwash)as well as the Negative control(placebo)groups. Whereas the tooth stain was increased significantly in the Positive control group, compared to the baseline score and the Negative controlgroup since 3 months of mouthrinsing. It was significantly increased after 6 months in the Experimental group, still less severe than the Positive control group. As for the oral side effect, the Experimental group showed less tongue accumulation, bad taste, compared to the Positive control group. From these results, mouthrinsing with Lipomyces starkeyi KSM 22 dextranase provided adjunctive benefits to toothbrushing, comparable to 0.12% chlorhexidine mouthwash in inhibition of plaque accumulation and gingival inflammation and local side effects were if anything less frequent and less intense than chlorhexidine, with long-term use of the mouthwash. All data had provided positive evidence for Lipomyces starkeyi KSM 22 dextranase as an antiplaque agent and suggested that further development of dextranase formulations for plaque control are warranted.
Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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2011.10a
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pp.475-478
/
2011
driver for safety always check the status of their vehicle, and it is essential to understand. But if you want to know the status of the driver of the vehicle in specialist referral time and money because it costs the operator shall be paid. Today's rapidly changing IT technology with the development of the various features of your phone to check the status of the vehicle was able to do. However, the car's existing phone system, car diagnostic expertise must be learned because it will reveal the status of the vehicle do not have the expertise to not highlight the need for diagnostic. To reflect these points in smartphone users to easily use their own vehicles at a time to determine the status of a system that is required. In this paper, OBD-II protocol conversion WiFi OBD-II connector, retrieving information from the driver of the vehicle replacement cycle of consumables required vehicle inspection, vehicle problems in real-time diagnostic information to the user ease of use shows the IOS implementation in the automotive supply was implemented based on the smartphone.
Journal of the Korea Academia-Industrial cooperation Society
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v.17
no.1
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pp.468-473
/
2016
The aim of this study was to measure the opening force of an access door of a pressurized smoke control zone and verify the reliability of the opening force. For the access door opening force, the opening load of the access door was measured before and after pressurized air had entered the smoke control zone. The reliability of the measured values was verified using the Anderson Darling's statistical analysis method of the Minitab Program. Because the analyzed P values were greater than 0.05 except for some floors before and after the operation of the smoke control equipment, the opening force was found to have 95% reliability. The normal distribution of the measured values showed no relationship with the operation of the smoke control equipment and the precision of the force gauge was believed to be reliable. The major factors for the optimal design of the pressurized smoke control equipment include the precision and reliability of the force gauge, the correct posture of the measuring person, and the same conditions for access doors. Therefore, a digital force gauge is believed to be suitable for measuring the opening force of the access door of a pressurized smoke control zone. In addition, standardization of the posture of a measuring person, the setup of the initial opening force of an access door, etc., are major variables for effective measurements of the door opening force of an access door.
Song Chae-Uk;Lee Yun-Sok;Park Young-Soo;Kim Jin-Kwon;Lee Yun-Chul;Kang Jeong-Gu
Proceedings of the Korean Institute of Navigation and Port Research Conference
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2005.10a
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pp.111-116
/
2005
The approaching waters of Po-hang port will be increased the traffic volume and passage of larger vessel according to the opening of Young-il new port in 2006. But the adjacent area of Po-hang port still exist the danger elements of safe navigation, the disordered navigation and traffic congestion. Therefore the safety of traffic must be improved in Po-hang vicinity area. This paper describes the status of marine traffic flow and navigational characteristics based on the marine traffic survey using the exclusive software, and the results of marine traffic survey classify into the ship's types and tonnage and track history of passing ships through the statistical method. Finally the examinations of main traffic route, traffic flow and navigational characteristics are discussed, and these results can be utilized the best design of ship's routing at the Po-hang approaching water.
Accident analysis are useful in the design stage of chemical plants and their surrounding structures. Also, analysis results are required for safety management of existing plants. In this paper, the fire and explosion effect by BTX released was evaluated. The computer program was prepared for accident analysis and adopted for evaluating the magnitude of fire (pool fire) and explosion (UVCE) effect. The thermal radiation was used as a measure of fire magnitude and the overpressure as a measure of explosion magnitude. And probit analysis was made for each case. As a case study, benzene tank model was used. The simulation results of explosion of benzene showed that the damage within 20 meters from the accident spot was severe and the damage beyond 60 meters was negligible. The simulation results of fire of benzene showed that the damage in summer is bigger than that in winter. And the damage of city located inland seems to be bigger than that of city in seaside. And thermal radiation effects was negligible beyond 40 meters-distance from the accident spot.
Objectives: A vertebral compression fracture (VCF) is characterized by back pain and fracture of a vertebral body on spinal radiography. VCFs of the thoraco lumbar spine are common in the elderly. In general, appropriate analgesics should be prescribed to reduce pain and, thus, promote early mobilization. The ideal treatment approach for VCFs has not been determined. In Korea, acupuncture and herbal medication have been used to treat VCFs for many years. There is empirical evidence that acupuncture might benefit patients with a VCF. However, no randomized, controlled, clinical trials evaluating the efficacy and the safety of acupuncture for treating a VCF have been published. Therefore, we designed a randomized, controlled, pilot, clinical trial to obtain information for the design of a further full scale trial. Methods: A five week protocol for a randomized, controlled, pilot, clinical trial is presented. Fourteen patients will be recruited and randomly allocated to two groups: a control group receiving interlaminar epidural steroid injections once a week for three weeks, and an experimental group receiving interlaminar epidural steroid injections plus acupuncture treatment (three acupuncture sessions per week for three weeks, nine sessions in total). The primary outcomes will be the pain intensity (visual analogue scale and PainVision$^{TM}$ system). The secondary outcome measurements will be the answers on the short form McGill pain questionnaire and the oswestry disability index. Assessments will be made at baseline and at one, three, and five weeks. The last assessment (week five) will take place two weeks after treatment cessation. This study will provide both an indication of feasibility and a clinical foundation for a future large scale trial. The outcomes will provide additional resources for incorporating acupuncture into existing treatments, such as nonsteroidal anti-inflammatory medications, narcotics and vertebral augmentation. This article describes the protocol.
Journal of Korean Society of Coastal and Ocean Engineers
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v.32
no.2
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pp.95-105
/
2020
In this study, using the CADMAS-SURF model, the characteristics of the wave pressures and the wave forces were analyzed according to the installation position of the parapet on top of the caisson, and the stability evaluation was carried out using estimated wave forces for the design wave condition. Numerical results show that adopting the rear-parapet reduces the front maximum wave pressures and wave forces, and the maximum wave pressure acting on the rear-parapet increases slightly compared to the front parapet, but the wave force acting on the rear-parapet has little effect on the stability of the breakwater due to the phase difference with the wave force acting on the front of the breakwater. In addition, impulsive wave pressures did not occur, as Yamamoto et al. (2013) pointed out the problem of the rear-parapet breakwater. As a result of the stability against sliding and overturning, it was estimated that the target safety factor of 1.2 could be secured by the self-weight of 13% less than the case of the front parapet. At this time, the maximum ground pressure was also reduced by 30%, and the applicability of the rear-parapet structure to the actual site was evaluated as high.
Small and medium-sized company workers are ill-prepared for retirement due to low wages and poor working conditions, as result, are likely to get into poverty in retirement. The purpose of this study is to conduct a case study on the current status of financial and non-financial retirement preparation of the small and medium-sized company workers. The main findings are as follows. First, the small and medium-sized company workers show the anxiety about retirement. Many pre-retirees worry that their retirement savings may not generate enough income in retirement, and the level of benefits paid in public pension is inadequate. Second, they are preparing for retirement in the areas of finance, health, working after retirement and social activity. Third, they are realistic and practical in retirement decisions makings. they are considering household budget downsizing, cutting education costs, the low-waged job choice and cash flow preference in retirement. The safety and reality in preparation for retirement are top considerations. In conclusion, this case study shows that pre-retirees of small and medium-sized companies are seeking diverse retirement solutions. We need to design integrated and practical retirement planning programs to support their specific retirement needs.
The technology review about risk of hypothermia of victim according to heat transfer characteristic of life raft and sea state can use accident correspondence of standing and sinking of ship. This study studied heat transfer characteristics required for the design of life raft and thermal insulation property analysis and evaluation methods. In addition, it is study for comprehend the risk of hypothermia and suggest analysis result that is experiment of thermal insulation property and body temperature property for decide of prediction the body temperature decline Thermal Analysis apply the finite element analysis method is comprehended the property of heat conductivity, convective effect of sea water and properties changes according to property of insulation material. it measure the heat flux with attach temperature sensor on body in order to comprehend the variation of body temperature with boarding a life raft experiment on a human body. This study validate results by comparing variation of temperature measured from experiment on a body with variation of temperature from finite element analysis model. Also, the criteria of hypothermia was discussed through result of finite element analysis.
A large number of people living in modern times prefer remaining unmarried or living alone independently for the reason of their own will or another person's will. This is because they dislike being interfered with by other persons or because there is a financial problem. This behavior has become mainstream in persons working for professional jobs, persons having a strong disposition toward individual activity or college students. In particular, career women pursuing their own comfortable life have the tendency to prefer single life. However, sometimes, they become a target of crime that targets and makes bad use of this point. For these reasons. Consequently, sometimes, they additionally install and use a security system such as door security guard at front door and so on. It is not so difficult to lock the door security guard at the front door. However, it is apt to be forgotten. And when they are on the bedspread before falling asleep, in case they should check whether the door security guard is locked or in case they should lock it, they should get up, go to the entrance, and check and lock the door security guard. They often don't lock the door security guard due to their feeling that it is all right because of annoyance and inconvenience. This paper is intended to work for safety from crime such as illegal housebreaking by more conveniently using the door security guard after designing and implementing a system that can remotely control the door security guard, using a smartphone as a method of resolving this annoyance and keeping life more safe.
본 웹사이트에 게시된 이메일 주소가 전자우편 수집 프로그램이나
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