• Korean Journal of Veterinary Service
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• v.46 no.3
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• pp.243-247
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• 2023

This study examined the dermatophytes of calves aged between 6 and 12 months in the Hanwoo calf auction market. Moreover, the research analyzed how dermatophytosis affected the auction price of Hanwoo calves based on their sex and age. The incidence rate of dermatophytosis was found to be 85 cases out of 1,955 calves (4.3%). The major location of dermatophytosis lesions were in the head region. Specifically, the highest prevalence was observed in the forehead (42.4%), followed by the eyes (30.1%), and the ears (18.8%). The auction prices of Hanwoo calves were observed that the average price for normal calves was 2,936,428 won, while calves with dermatophytosis were sold at 2,767,059 won. Comparing auction prices according to gender and age, it was observed that male calves and calves aged between 8 and 12 months had significantly lower auction prices compared to normal calves. The results provided valuable insights into the current situation of dermatophytosis in Hanwoo calves. Moreover, analyzing the impact of dermatophytosis on the auction prices of these calves, it has generated essential data that can serve as a foundation for implementing and enhancing ongoing management and prevention measures for dermatophytosis in cattle.

• Korean Journal of Veterinary Research
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• v.38 no.4
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• pp.823-828
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• 1998

This study was carried out to determine the causative agent and the clinical features of dermatophytosis occurred in 3 dogs from Tae-gu, Korea between 1996 and 1997. Specimens of hair and scale, collected from skin lesions were inoculated on potato dextrose agar and mycobiotic agar supplemented with thiamine and inositol. The agar plates were incubated at $25^{\circ}C$ for 2 weeks. Growing fungi isolated were identified by the morphological and growth characterization on bromocresol purple-milk solids-glucose medium, Christensen urea broth and trichophyton media, and by hair perforation tests. Skin lesions were observed in legs, abdomen, ears, face and head with alopecia of various sizes accompanied by itching and/or inflammation. The causative agent of dermatophytosis in the 3 dogs was identified as Microsprum gypseum and Trichophyton rubrum (mixed infection, dog 1), T rubrum (dog 2) and T raubitschekii (dog 3). The dermatophytosis by T rubrum and T raubitschekii was first found on animals in Korea.

• Korean Journal of Veterinary Service
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• v.26 no.1
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• pp.57-65
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• 2003

The present study was conducted to examine the outbreak state of bovine dermatophytosis in 14 farms(4 dairy farms, 10 Korean indigenous cattle farms) in Gyeongbuk province from November 2000 to November 2001. The causative agents of dermatophytosis was identified by mycological examination. Antifungal susceptibility test of 26 isolates was performed by agar dilution method, using 5 antifungal drugs. Prevalence of bovine dermatophytosis was found to be 13.5%(90/665) in dairy cattle farms and 14.5%(220/1,520) in Korean indigenous cattle farms. The most common age at which this disease occurred was 2-12 months. This disease usually occurred from winter to spring and the occurrence subsequently decreased in the summer. But 4 Korean indigenous cattle farms with poorly hygienic status were occurred all the year round. The causative agent was identified as Trichophyton verrucosum exclusively in these case. Antifungal susceptibility test of T verrucosum (26 strains) was performed by agar dilution method, using 5 antifungal drugs including tolnaftate, griseofulvin, ketoconazole, amphotericin B and terbinafine. All isolates were highly sensitive to 5 antifungal drugs (geometric mean MICs 0.004∼0.032 $\mu\textrm{g}$/$m\ell$). The isolates were the most sensitive to especially tolnaftate.

• Korean Journal of Veterinary Service
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• v.47 no.3
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• pp.115-122
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• 2024

Bovine dermatophytosis is a highly contagious disease that adversely affects animal growth and reduces meat and milk production. Nutritional deficiencies and immune status are suspected risk factors, but their roles remain unclear. This study investigates the association between trace minerals, vitamins, serum biochemical parameters, and immune-related cytokines with bovine dermatophytosis. Forty calves aged 6~7 months were selected and raised together on the same farm. They were divided into two groups: the control group (n=20) and the infected group (n=20). Serum was collected and analyzed for serum trace minerals, vitamins, biochemical parameters, and cytokine levels. Trichophyton verrucousm was isolated from infected calves. The infected calves had significantly lower zinc (P<0.001) and vitamin E (P=0.02) levels and significantly higher interleukin (IL)-6 (P=0.014) and IL-17A (P=0.018) levels. Regarding serum biochemical parameters, glucose (P=0.008) and total bilirubin (P=0.003) levels were significantly higher in the infected calves than in healthy ones. Hyperglobulinemia and high alkaline phosphatase levels were observed in the infected calves, without statistical significance. Our findings suggest the necessity of considering nutritional elements such as zinc and vitamin E for the prevention and treatment of bovine dermatophytosis. Additionally, the observed changes in immune and serum biochemistry factors post-infection may provide a foundation for future research on the host's biological responses to infection.

• Korean Journal of Veterinary Research
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• v.21 no.2
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• pp.113-116
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• 1981

This experiment was undertaken to determine the causative agent of dermatophytosis occured in the 3 common seals and a elephant which were derived from the Tae-gu and Busan zoological gardens. Direct microscopic examination, culture and pathogenicity test were performed for the samples obtained from the skin lesions of the affected common seals and elephant. The causative agent was identified as Trichophyton mentagrophytes exclusively in these cases, and the present report describes the first cases of the common beat and elephant ringworm.

• Journal of Veterinary Clinics
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• v.13 no.1
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• pp.77-80
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• 1996

인도의 아메다바드 동물원에서 사육중인 1년생의 수컷 우는 사슴(Muntiacus muntjak)에서 피부사상균증이 발생했다. 발병된 사슴의 얼굴, 머리 및 목 부위 피부에는 모양이 불규칙하고 각피성인 여러개의 회백생 병변을 나타내었다. potassium hydroxide기법에 의해 피부병변에서 Trichophyton verrucosum이 검출되었다. 감염된 피부와 털 시료를 곰팡이 배지에 배양하여 같은 병원체가 검출되었다. 이 사슴과 밀접하게 접촉하였던 사육사에게서는 감염증이 확인되지 않았다. 동물원 동물의 피부염을 감별하는데 있어서 피부사상균을 고려해야 한다는 점이 강조되었다. 저자들의 소견으로는 이것이 인도산 우는 사슴에서 발생한 Trichophyton verrucosum 감염증으로써 최초의 확진된 보고이다.

• The Korean Nurse
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• v.3 no.3 s.11
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• pp.80-84
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• 1964

• Korean Journal of Veterinary Research
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• v.36 no.2
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• pp.389-394
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• 1996

This study was carried out to determine the causative agent of dermatophytosis in 7 horses, and to examine the skin mycofloras on 84 healthy and 7 diseased horses which were derived from Jae-ju and Kyonggi, Korea in 1994~1995. Specimens of hair and scale were collected from skin lesions(or normal skins) and inoculated directly on potato dextrose agar and mycobiotic agar. These agar plates were incubated at $25^{\circ}C$ for 2 weeks. Growing fungi were isolated and identified by the morphological and nutritional characteristics. Lesions were found on the hind legs of an infected horses and each lesion was round or oval(1~4 cm) in shape accompanied by severe itching. The causative agent of the 7 equine dermatophytosis was identified as Trichophyton equinum. The skin mycofloras were Penicillium(69.0%), Aspergillus(63.2%), Cladosporium(51.7%), Fusarium(31.0%), Mucor(28.7%), Absidia(18.4%), Alternaria(17.2%), Acremonium(11.5%), Paecilomyces and Phycomyces(6.9%), Rhizopus(5.6%), Trichoderma(4.6%), Scopulariopsis and Trichophyton(3.5%), Beauveria(2.3%), Tritiracheum, Sporothrix, Curvularla, Aureobasidium and Chaetomium(1.2%), and Yeast(27.6%).

• The Korean Journal of Mycology
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• v.21 no.2
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• pp.133-139
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• 1993

Common dermatophytosis in upper Egypt were studied at three hospitals in Minia city. Tinea corporis (ringworm of glabrous skin) was diagnosed in 127 patients (84 males and 53 females). Trichophyton was the most common genus and was represented by 6 species among which T. violaceum was the commonest fungus. Microsporum was represented by 4 species and M. canis was the prevalent species. Tinea pedis (ringworm of the foot) was noticed in 22 cases (13 males and 9 females) and also Trichophyton and Microsporum were the causal organisms. Three species of Trichophyton namely: T. violaceum, T. kuryngei and Trichophyton sp. were isolated. Tinea cruis (ringworm of the groin) was diagnosed in 21 patients (16 males and 5 females). Epidermophyton floccosum was the most prevalent fungus associated with tinea cruris whereas Trichophyton and Candida were less frequent. Tinea unguium (ringworm of the nail) was diagnosed in 9 patients, 8 were females and one was male and the age incidence ranged between 5 and 55 years. M. canis occurred in 2 cases and T. mentagrophytes in one case. Out of 86 cases of tinea versicolor, 71 were males and 15 were females. Malassezia furfur was the main causal agent. All patients of candidiasis and paronychia were females and Candida was the most prevalent causal agent.

• Korean Journal of Veterinary Research
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• v.45 no.2
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• pp.255-261
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• 2005

The purpose of this study is to compare hepatotoxicity of each treatment for dermatophytosis; one is the administration of the ketoconazole only and the other, ketoconazole with diphenyl-dimeththyl-dicarboxylate. Have chosen the range of 14-24 months of healthy dogs divided by two groups (group 1 and group 2) for the experiment of which test proved positive in dermatophytosis diagnosis and showed normal reaction in terms of physical examination, blood chemistry and especially of liver function. Group 1 was administrated ketoconazole orally at 10 mg/kg/day and of same dose of ketoconazole with diphenyl-dimethyl-dicarboxylate for group 2. After administering, we have tested two groups by blood collecting every one week in order to check the differences of hepatotoxicity state through AST, ALT and r-GTP, the barometers of liver function which lasted for 12 weeks. Moreover, tested Indocyanine Green (ICG), known as susceptible gauge of function of excretion before starting the experiment and tested ICG as well after 12 weeks. The experiment of result the value of group 1 in AST, ALT and r-GTP has been highly rised after administering ketoconazole for 10 weeks meanwhile, of group 2 has shown a steady state troughout the whole experiment. For ICG test, we injected 0.5 mg/kg of ICG into a vein for both groups and tested the retention rate at regular interval of 15, 30, 45 minutes. The results of retention rate in two groups were similar to before the drug administration. However, after 12 weeks the retention rate of group 1 has been delayed, on the other hand, retention rate of group 2 were a steady state. In conclusion, the administration of ketoconazole only for a long period of time induced hepatotoxicity where as, the administration of ketoconazole with diphenyl-dimethyl-dicarboxylate didn't induce hepatotoxicity. Therefore, when doctors prescribes for a dog with dermatophytosis should not administrate ketoconnazole itself but with diphenyl-dimethyl-dicarboxylate and one who has abnormal condition of liver function should not be prescribed ketoconazole treatment. If there is a case needed to prescribe ketoconazole treatment, the regular monitoring should be accompanied by at the same time.