• 제목/요약/키워드: Delta-1

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개선된 DWA 구조를 갖는 3차 3-비트 SC Sigma-Delta Modulator (A $3^{rd}$ order 3-bit Sigma-Delta Modulator with Improved DWA Structure)

  • 김동균;조성익
    • 대한전자공학회논문지SD
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    • 제48권5호
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    • pp.18-24
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    • 2011
  • DEM(Dynamic Element Matching) 기법중의 하나인 DWA(Data Weighted Averaging)는 멀티비트 Sigma-Delta Modulator에서 피드백 DAC의 단위요소 커패시터 부정합으로 인한 비선형성을 제거하기 위하여 널리 이용된다. 본 논문에서는 기존 DWA 구조에서 적용된 클록 타이밍을 조정하여 양자화기 데이터 코드 출력을 Latch 하는 $2^n$ Register 블록을 $2^n$ S-R latch 블록으로 대체하여 MOS Tr.를 줄임과 더불어 여분의 클록을 제거하였고, n-bit 데이터 코드를 지연시키기 위해 사용되는 2개의 n-비트 Register 블록을 1개의 n-비트 Register 블록으로 감소시켰다. 개선된 DWA 구조를 이용하여 3차 3-비트 SC(Switched Capacitor) Sigma-Delta Modulator를 설계한 후, 입력 주파수 20kHz, 샘플링 주파수 2.56MHz에서 0.1% DAC 단위 요소 커패시터 부정합을 갖도록 하여 시뮬레이션 한 결과 기존의 구조와 동일한 해상도를 얻을 수 있었고, 222개의 MOS Tr. 수를 줄일 수 있었다.

훈증제 ethylene oxide가 문화재의 색도에 미치는 영향 (Influence of Ethylene Oxide Fume upon Chromaticity of Cultural Material)

  • 이길성;박병빈;최기영
    • 한국환경보건학회지
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    • 제28권5호
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    • pp.4-12
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    • 2002
  • It is well-known method to use Ethylene Oxide (ETO) as a fumigant to preserve cultural heritage from the attack of some bacteria and insects. In this article, we investigated co]or change of some cultural material upon treating ETO. The cultural material was selected from Korean paper (hanji), ancient books, blue prints, pigments (DA, DB, DC, DD, DE and DF). hemp cloths, and colored pictures (DG, DH, Dl, DJ, DK). The $\Delta$E value in chromaticity coordinates for each item was obtained upon treatment with ETO at concentration of 200, 250, 380, 500, 710 g/m$^3$ respectively. The $\Delta$E value was derived from the equation of L*at with the data checked 24 hr, 48 hr, and 72 hrs respectively. The Korean papers(hanji) showed slightly change in color by $\Delta$E 0.8. In the case of ancient books, it showed $\Delta$E 2.91 which was easily distinguishable with the naked eyes. For the almost 73% of blue prints, the value of $\Delta$E was as much as more than 4.0 that it is recommended not to use. In the case of pigments, the value of $\Delta$E was ranged from 0.15 up to 4.0 so that it should be very careful before use. The hemp cloth dyed with natural indigo showed less than 1.00 in $\Delta$E, while various colored hemp cloth showed wide range of $\Delta$E from 1.00 to 4.00. Finally, from the fact that the color change was as small as less than 1.00 for the colored pictures, it is thought that treatment with ETO is one of method to be used to this purpose.

δ-Catenin Increases the Stability of EGFR by Decreasing c-Cbl Interaction and Enhances EGFR/Erk1/2 Signaling in Prostate Cancer

  • Shrestha, Nensi;Shrestha, Hridaya;Ryu, Taeyong;Kim, Hangun;Simkhada, Shishli;Cho, Young-Chang;Park, So-Yeon;Cho, Sayeon;Lee, Kwang-Youl;Lee, Jae-Hyuk;Kim, Kwonseop
    • Molecules and Cells
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    • 제41권4호
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    • pp.320-330
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    • 2018
  • ${\delta}$-Catenin, a member of the p120-catenin subfamily of armadillo proteins, reportedly increases during the late stage of prostate cancer. Our previous study demonstrates that ${\delta}$-catenin increases the stability of EGFR in prostate cancer cell lines. However, the molecular mechanism behind ${\delta}$-catenin-mediated enhanced stability of EGFR was not explored. In this study, we hypothesized that ${\delta}$-catenin enhances the protein stability of EGFR by inhibiting its lysosomal degradation that is mediated by c-casitas b-lineage lymphoma (c-Cbl), a RING domain E3 ligase. c-Cbl monoubiquitinates EGFR and thus facilitates its internalization, followed by lysosomal degradation. We observed that ${\delta}$-catenin plays a key role in EGFR stability and downstream signaling. ${\delta}$-Catenin competes with c-Cbl for EGFR binding, which results in a reduction of binding between c-Cbl and EGFR and thus decreases the ubiquitination of EGFR. This in turn increases the expression of membrane bound EGFR and enhances EGFR/Erk1/2 signaling. Our findings add a new perspective on the role of ${\delta}$-catenin in enhancing EGFR/Erk1/2 signaling-mediated prostate cancer.

쌀의 저장중 수분이동에 의한 균열현상에 관한 연구 (Cracking of Rice Caused by Moisture Migration during Storage)

  • 목철균;이상기
    • 한국식품과학회지
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    • 제31권1호
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    • pp.164-170
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    • 1999
  • 저장 중 쌀의 수분이동에 따른 균열현상을 구명하고 균열을 발생시키는 임계조건을 산출하여 이를 토대로 쌀의 균열을 방지할 수 있는 저장조건을 확립하였다. 쌀의 평형상대습도와 노출된 환경의 상대습도의 차이$({\Delta}ERH)$가 적을 때는 균열이 발생하지 않은 반면, 그 차이가 임계치보다 클 때는 균열이 발생하였으며 균열의 발생정도는 쌀의 평형상대습도와 환경의 상대습도의 차이가 클수록 심하게 나타났다. 탈습환경 하에서는 불규칙한 형상의 균열이 쌀알의 외부에 발생하였으며 흡습환경 하에는 규칙적인 형상의 균열이 쌀알의 내부에 축방향과 수직방향으로 방사상으로 발생하였다. 노출시간별 균열발생 패턴을 Weibull함수에 의거하여 해석한 결과, ${\Delta}ERH$가 클수록 균열속도상수가 증가하였다. 동할미 발생률은 In$({\Delta}ERH)$에 따라 직선적으로 증가하였으며, 임계 균열발생 상대 습도차(critical crack-inducing ${\Delta}ERH$)는 탈습시 $11.3{\sim}16.4%$, 흡습시 $10.8{\sim}17.1%$의 값을 보였다. 실험결과를 토대로 수분함량 및 수분활성도 별 쌀의 안전저장 상대습도를 나타내는 diagram을 제시하였다.

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Biochemical and Thermal Stabilization Parameters of Polygalacturonase from Erwinia carotovora subsp. carotovora BR1

  • Maisuria, V.B.;Patel, V.A.;Nerurkar, A.S.
    • Journal of Microbiology and Biotechnology
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    • 제20권7호
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    • pp.1077-1085
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    • 2010
  • With an emphasis on its thermal behavior with different pHs and salts, the kinetic and thermodynamic parameters of the purified polygalacturonase (PG) from E. carotovora subsp. carotovora (Ecc) BR1 were studied, as the characterization of an enzyme is significant in the context of burgeoning biotechnological applications. The thermodynamic parameters for polygalacturonic acid hydrolysis by the purified PG were ${\Delta}H^*$=7.98 kJ/mol, ${\Delta}G^*$=68.86 kJ/mol, ${\Delta}S^*$=-194.48 J/mol/K, ${\Delta}G_{E-S}$=-1.04 kJ/mol, and ${\Delta}G_{E-T}$=-8.96 kJ/mol. In addition, its turnover number ($k_{cat}$) was 21/sec. The purified PG was stable within a temperature range of $20-50^{\circ}C$ and was deactivated at $60^{\circ}C$ and $70^{\circ}C$. The thermodynamic parameters (${\Delta}H^*$, ${\Delta}G^*$, ${\Delta}S^*$) for the irreversible inactivation of the PG at different temperatures ($30-60^{\circ}C$) were determined, where the effectiveness of various salts and different pHs (4-8) for the thermal stability of the PG were also characterized. The efficacy of various salts for the thermal stability of the PG was in the following order: $MgCl_2$ > $BaCl_2$ > KCl > $CaCl_2$ >NaCl. Therefore, the present work presents the biochemical, substrate hydrolysis thermodynamics and the thermal stabilization parameters of the PG from Ecc.

CELP 보코더에서 델타 피치 검색 방법 개선에 대한 연구 (An Algorithm to Reduce the Pitch Computational Complexity Using Modified Delta Searching in G.723.1 Vocoder)

  • 민소연;배명진
    • 음성과학
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    • 제11권3호
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    • pp.165-172
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    • 2004
  • In this paper, we propose the computational complexity reduction methods of delta pitch search that is used in G.723.1 vocoder. In order to decrease the computational complexity in delta pitch search the characteristic of proposed algorithms is as the following. First, scheme to reduce the computational complexity in delta pitch search uses NAMDF. Developed the second scheme is the skipping technique of lags in pitch searching by using the threshold value. By doing so, we can reduce the computational amount of pitch searching more than 64% with negligible quality degradation.

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Enhanced Transformation Efficiency of an Anticoagulant Hirudin Gene into Saccharomyces cerevisiae by a Double ${\delta}-Sequence$

  • Kim, Myoung-Dong;Yoo, Young-Je;Rhee, Sang-Ki;Seo, JIn-Ho
    • Journal of Microbiology and Biotechnology
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    • 제11권1호
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    • pp.61-64
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    • 2001
  • Delta-integration vectors were constructed for the purpose of achieving homologous integration of the hirudin expression cassette into the chromosome of Saccharomyces cerevisiae. A double $\delta$ system truncated with the unnecessary bacterial genes, and consequently having a reduced insert size for integration, showed a four-fold increase in transformation efficiency at given DNA concentrations, and as a result, the constructed recombinant yeast strain had a 1.3-fold enhancement in hirudin expression level compared with a single $\delta$ system.

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A Clock Regenerator using Two 2nd Order Sigma-Delta Modulators for Wide Range of Dividing Ratio

  • Oh, Seung-Wuk;Kim, Sang-Ho;Im, Sang-Soon;Ahn, Yong-Sung;Kang, Jin-Ku
    • JSTS:Journal of Semiconductor Technology and Science
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    • 제12권1호
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    • pp.10-17
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    • 2012
  • This paper presents a clock regenerator using two $2^{nd}$ order ${\sum}-{\Delta}$ (sigma-delta) modulators for wide range of dividing ratio as defined in HDMI standard. The proposed circuit adopts a fractional-N frequency synthesis architecture for PLL-based clock regeneration. By converting the integer and decimal part of the N and CTS values in HDMI format and processing separately at two different ${\sum}-{\Delta}$ modulators, the proposed circuit covers a very wide range of the dividing ratio as HDMI standard. The circuit is fabricated using 0.18 ${\mu}m$ CMOS and shows 13 mW power consumption with an on-chip loop filter implementation.

CAM 플라스미드를 함유하는 Pseudomonas putida PpG1에서 TOL 플라스미드이 DNA 재배열 (DNA Rearrangement of TOL Plasmid in Pseudomonas putida PpGl Harbouring CAM Plasmid)

  • 전효곤;조경연;고영희
    • 한국미생물·생명공학회지
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    • 제18권4호
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    • pp.433-436
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    • 1990
  • 접합에 의한 P.putida mt-2의 TOL를 CAM 함유 P.putida PpG1으로 이동시켜 형성된 접합주 P.Putida CST3A는 작아진 TOL(TOL$\Delta$)를 가지고 있었지만, m-toiuate를 분해할 수 있었다. 접합에 의한 이동실험은 CAM에 결합되어 CAM:TO* 플라스미드를 형성하고 있었다. 불화합성 Inc P9군에 속하는 NAH를 CAM:TOL* 과 TOL$\Delta$을 가지는 P.putida CST3A로 이동시키면 TOL$\Delta$의 방출이 관찰되었으나 m-toluate 대사에는 아무런 영향을 미치지 않았다.

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A NATURAL MAP ON AN ORE EXTENSION

  • Cho, Eun-Hee;Oh, Sei-Qwon
    • 충청수학회지
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    • 제31권1호
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    • pp.47-52
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    • 2018
  • Let ${\delta}$ be a derivation in a noetherian integral domain A. It is shown that a natural map induces a homeomorphism between the spectrum of $A[z;{\delta}]$ and the Poisson spectrum of $A[z;{\delta}]_p$ such that its restriction to the primitive spectrum of $A[z;{\delta}]$ is also a homeomorphism onto the Poisson primitive spectrum of $A[z;{\delta}]_p$.