• Bulletin of Food Technology
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• v.19 no.2
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• pp.149-165
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• 2006

• Journal of the Korea Institute of Building Construction
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• v.9 no.5
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• pp.111-117
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• 2009

With the current trend in the industry toward increasingly complex, diversified and large construction projects, advanced countries in the construction field have already introduced and applied a variety of methods for placing orders in order to cope with such changes in construction circumstances. In Korea, there have been efforts to continuously improve approaches to placing an order. With the aim of diversifying the methods of Delivery Systems, the "Technical Proposal Type Bid," and the "Design Competition and Technical Proposal Type Bid" were introduced through a revision of Korea's contract law enforcement ordinance. In line with the government's efforts, criteria for a method of placing an order that is suitable for a public construction project should be presented. This study enumerates the current issues using a survey for construction projects already placed and an analysis of the current status, and presents the selection criteria for Delivery Systems by business type as an improvement for the problem.

• CELLMED
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• v.11 no.1
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• pp.6.1-6.7
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• 2021

In situ gelling devices, as they enter the body, are dosage forms in the shape of the sol but turn into gel types under physiological circumstances. Transition from sol to gel is contingent on one or a mixture of diverse stimuli, such as transition of pH control of temperature, irradiation by UV, by the occurrence of certain ions or molecules. Such characteristic features may be commonly employed in drug delivery systems for the production of bioactive molecules for continuous delivery vehicles. The technique of in situ gelling has been shown to be impactful in enhancing the potency of local or systemic drugs supplied by non-parenteral pathways, increasing their period of residence at the absorption site. Formulation efficacy is further improved with the use of mucoadhesive agents or the use of polymers with both in situ gelling properties and the ability to bind with the mucosa/mucus. The most popular and common approach in recent years has provided by the use of polymers with different in situ gelation mechanisms for synergistic action between polymers in the same formulation. In situ gelling medicine systems in recent decades have received considerable interest. Until administration, it is in a sol-zone and is able to form gels in response to various endogenous factors, for e.g elevated temperature, pH changes and ions. Such systems can be used in various ways for local or systemic supply of drugs and successfully also as vehicles for drug-induced nano- and micro-particles. In this review we will discuss about various aspects about use of these in situ gels as novel drug delivery systems.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.12 no.4
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• pp.1527-1552
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• 2018

The rapidly-evolving demand of applications using wireless sensor networks in several areas such as building and industrial automation or smart cities, among other, makes it necessary to determine and provide QoS support mechanisms which can satisfy the requirements of applications. In this paper we propose a mechanism that establishes different QoS levels, based on Publish/Subscribe model for wireless networks to meet application requirements, to provide reliable delivery of packet and timeliness. The first level delivers packets in a best effort way. The second one intends to provide reliable packet delivery with a novel approach for Retransmission Timeout (RTO) calculation, which adjusts the RTO depending on the subscriber Packet Delivery Ratio (PDR). The third one provides the same reliable packet delivery as the second one, but in addition, it provides data aggregation trying to be efficient in terms of energy consumption and the use of network bandwidth. The last one provides timeliness in the packet delivery. We evaluate each QoS Level with several performance metrics such as PDR, Message Delivery Ratio, Duplicated and Retransmitted Packet Ratio and Packet Timeliness Ratio to demonstrate that our proposal provides significant improvements based on the increase of the PDR obtained.

• IE interfaces
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• v.24 no.4
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• pp.435-446
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• 2011

Performance measures play a critical role in formulating mail delivery strategies and evaluating actual results. Nevertheless, the existing method and corresponding system to determine the standard workloads of mailmen is developed without careful consideration of real delivery environments and various requirements of mailmen. Hence, the current system is insufficient for optimal management of workloads and shows substantial gaps when compared to the results of actual work-site. This study considers how to improve the current workload management system of mailmen. We first performed the as-is analysis of the mail delivery service and then developed a prototype of advanced delivery workload management system. The to-be system consists of five subsystems which can be grouped into three categories; master data management, workloads management, performance analysis. Our results can be a valuable guide for the development of real system for measuring and balancing the workloads of mailmen.

• Journal of the Korean housing association
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• v.27 no.4
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• pp.33-46
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• 2016

In era of lowbirth, aging population, low growth and social polarization, the effective welfare delivery systems are taking on added significance than past years. Public housing welfare resources, such as public rental housing, housing voucher, affordable housing loan, are more diversified and expanded. These programs could work effectively by the comprehensive interlink and community based delivery system. From the standpoint of recipients, how effectively the substantial benefits of welfare resources being delivered to each individual is more important than how much welfare resources being produced totally. This study aimed to explore the reform of public housing welfare delivery system. For this purpose, diagnosed the current states and key issues related to public delivery system, and analyzed what kinds of housing welfare services should be strengthened, and finally suggested the collaboration among the public sectors (local government, LH, HUG, HF etc.) and the partnership with non-profit organizations. Main research implications are as follows. The main housing welfare services which could be categorized as the housing welfare center's role are advice & information offering, several public resources interlink and accessibility improvement, community based network construction, etc. And the most important key for successful delivery system reorganization is the collaborative operation of the public sectors and local government, non-profit organizations.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.44 no.3
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• pp.106-116
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• 2021

This paper considers a joint problem for blood inventory planning at hospitals and blood delivery planning from blood centers to hospitals, in order to alleviate the blood service imbalance between big and small hospitals being occurred in practice. The joint problem is to determine delivery timing, delivery quantity, delivery means such as medical drones and legacy blood vehicles, and inventory level to minimize inventory and delivery costs while satisfying hospitals' blood demand over a planning horizon. This problem is formulated as a mixed integer programming model by considering practical constraints such as blood lifespan and drone specification. To solve the problem, this paper employs a Lagrangian relaxation technique and suggests a time efficient Lagrangian heuristic algorithm. The performance of the suggested heuristic is evaluated by conducting computational experiments on randomly-generated problem instances, which are generated by mimicking the real data of Korean Red Cross in Seoul and other reliable sources. The results of computational experiments show that the suggested heuristic obtains near-optimal solutions in a shorter amount of time. In addition, we discuss the effect of changes in the length of blood lifespan, the number of planning periods, the number of hospitals, and drone specifications on the performance of the suggested Lagrangian heuristic.

• International journal of advanced smart convergence
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• v.12 no.1
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• pp.220-229
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• 2023

The development of logistics technology due to the 4th Industrial Revolution and logistics 4.0 has changed the logistics environment from offline to online, and the growth of the online market has accelerated due to the recent increase in non-face-to-face delivery due to COVID-19. Such growth in the online market has expanded the logistics market for delivery, and contributes to creating an advanced logistics ecosystem as last mile services and logistics technologies begin to grow together. As traffic and environmental problems arise as a result, interest in transportation means of cargo increases, and changes to cargo electric vehicles and delivery cycles are being considered. However, since mass transportation of transportation focused on terminal delivery such as cargo electric vehicles and delivery cycles is limited in handling large quantities in urban areas, methods for efficiently transporting cargo while considering the environment are being devised. In order to solve such environmental problems and increase the efficiency of logistics delivery in urban areas, technologies using underground spaces based on existing urban railroads are being developed. In this study, a study was conducted on the establishment of evaluation criteria for selecting a test bed, which is a space for applying the system.

• Journal of Pharmaceutical Investigation
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• v.37 no.5
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• pp.291-295
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• 2007

Prostaglandin $E_1\;(PGE_1)$ was formulated as two self-microemulsifying drug delivery systems (SMEDDS) composed of Cremophor $EL^{(R)}$ or Cremophor $ELP^{(R)}$ as a surfactant, ethanol as a cosurfactant and Labrafac $CC^{(R)}$ as an oil to develop liquid preparation for the treatment of erectile dysfunction. In pseudo-ternary phase diagram, viscous gel area and microemulsion area were defined. In the measurement of viscosity, the viscosity of two formulations increased gradually upon the addition of water and it decreased from the water contents over 40%. With excessive water, the present systems formed a microemulsion spontaneously. From these results, rte could expect that the present liquid $PGE_1$ SMEDDS formulations might stay within the urethra in the viscous state when contacting the moisture of the urethra and can be easily eliminated by urination. In long-term stability study, we could select one formulation more stable at the shelf storage condition of $4^{\circ}C$.

• Journal of Korean Institute of Industrial Engineers
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• v.40 no.4
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• pp.435-441
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• 2014

This paper considers a single-product problem for inbound lot-sizing and outbound dispatching at a third-party warehouse, where the demand is dynamic over the discrete time horizon. Each demand must be delivered into the corresponding delivery time window which is the time interval characterized by the earliest and latest delivery dates of the demand. Ordered products are shipped by heterogeneous container types. Each container type has type-dependent carrying capacity and the unit freight cost depends on each container type. Total freight cost is proportional to the number of each container type used. Also it is assumed that related cost functions are concave and backlogging is not allowed. The objective of the paper is to simultaneously determine the optimal inbound lot-sizing and outbound dispatching plans that minimize total costs which include ordering, shipping, and inventory holding costs. The optimal solution properties are characterized for the problem and then a dynamic programming algorithm is presented to find the optimal solution.