• KSII Transactions on Internet and Information Systems (TIIS)
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• 제5권1호
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• pp.105-122
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• 2011

The fundamental design goal of wireless sensor MAC protocols is to minimize unnecessary power consumption of the sensor nodes, because of its stringent resource constraints and ultra-power limitation. In existing MAC protocols in wireless sensor networks (WSNs), duty cycling, in which each node periodically cycles between the active and sleep states, has been introduced to reduce unnecessary energy consumption. Existing MAC schemes, however, use a fixed duty cycling regardless of multi-hop communication and traffic fluctuations. On the other hand, there is a tradeoff between energy efficiency and delay caused by duty cycling mechanism in multi-hop communication and existing MAC approaches only tend to improve energy efficiency with sacrificing data delivery delay. In this paper, we propose two different MAC schemes (ADS-MAC and ELA-MAC) using closed-loop control in order to achieve both energy savings and minimal delay in wireless sensor networks. The two proposed MAC schemes, which are synchronous and asynchronous approaches, respectively, utilize an adaptive timer and a successive preload frame with closed-loop control for adaptive duty cycling. As a result, the analysis and the simulation results show that our schemes outperform existing schemes in terms of energy efficiency and delivery delay.

• 한국정보통신학회논문지
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• 제22권5호
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• pp.764-771
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• 2018

연구는 인포그래픽 표현의 다양화와 전달 효율성을 시각적 조형성을 중심으로 파악하는 기초연구로, 조형적 특성에 중점을 두었다. 이를 위해 기하학적 유형과 유희적 유형으로 구분하여 각각의 조형적 속성들을 도출하여 유의미한 차이가 있음을 증명하였고 인포그래픽의 유형별 조형성과 내용전달의 상호 관계성을 분석하였다. 그 결과 기하학적 유형은 규칙성, 명확성, 시인성, 내용전달성이, 유희적 유형은 유희성, 시인성, 명확성, 내용전달성의 속성이 도출되었다. 또한 내용전달을 중심으로 나머지 속성의 관계를 분석한 결과, 기하학적 유형에서는 규칙성과 시인성이 내용전달 효과에 유의미한 긍정적인 영향력을 주고 있으며 유희적 유형에서는 유희성과 명확성이 내용전달에 유의미한 영향을 주는 것으로 나타났다. 따라서 인포그래픽의 조형성은 시각화 과정에서의 유의미한 차이에 의해 표현 유형을 구분하며 내용전달의 영향을 주는 세부 요인 또한 조형적 요소에 있음을 실증적으로 확인하였다.

• 대한약학회:학술대회논문집
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• 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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• pp.427.1-427.1
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• 2002

To improve stability and transfection efficiency, a novel combination of cationic emulsion and galactosylated chitosan was developed for targeted gene delivery. Six formulations of cationic liposome and our novel emulsion were prepared for comparison of stability and transfection efficiency. Cationic liposomes composed of 3［N-(N.N dimethylaminoethylene) carbamoyl］ cholesterol (DC-Chol) and dioleyl phophatidyl ethanolamine (DOPE) were prepared by extrusion method and cationic emulsions composed of DC-Chol. DOPE. castor oil, and Tween 80 were prepared by sonication method. (omitted)

• 한국농공학회논문집
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• 제52권5호
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• pp.27-35
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• 2010

The characteristics of delivered nutrient loads were analyzed and the regression equations to estimate delivery ratios of nutrients (TN and TP) were developed using HSPF simulation results at six subwatersheds within the Bochung A unit watershed during 1998-2007. TN delivery ratio was higher than TP delivery ratio because significant amounts of TP was considered to be attached at soil as ${PO_4}^-$ during delivery process from discharged point of nutrient source to main stream. As a results of correlation analysis, factors related to geomorphic characteristics had not statistical correlation with TN and TP delivery ratios. TN loading rate from living and specific stream flow had statistical negative and positive correlation, respectively, with TN delivery ratio. TP loading rates from all sources and from land cover and specific stream flow had statistical negative, negative and positive correlation, respectively. The specific stream flow represents the most strong correlation with nutrient delivery ratios. The regression equations to estimate delivery ratios for TN and TP were developed by including statistical correlated factors and showed high efficiency of 0.98 and 0.95 of coefficient of determination for TN and TP, respectively.

• KSBB Journal
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• 제13권4호
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• pp.418-423
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• 1998

Cellular transfections with cationic liposomes are widely empolyed for gene and oligonucleotide transfer in vitro because of their safety and ease of use. However, they still suffer from the low transfection efficiency comparing with viral vectors. Substantial effort shave been focused on increasing transfection efficiency by supplementing the liposome/DNA complexes(lipoplex) with various components. In this work, we tired three kinds of supplements, Poly-L-lysine(PLL), transferrin and a mixture of anionic lipids(PS/PE/PC), to study their effects on gene transfer yield and gene expression efficiency. PLL, a polycationic polymer, enhanced gene transfer yield by 3 times but the gene expression efficiency was increased only by 1.5 times. this result implies that PLL can enhance the transfection efficiency mainly by increasing the rate of outermembrane transport of lipoplex into the cells. On the other hand, transferrin which can facilitate the gene transfer via ligand-receptor interaction gave not only increased gene transfer yield but also enhanced gen expression efficiency by 2.8 times. Transferrin seems to contribute to the escape of plasmid from endosomes through ligand-receptor recycle mechanism. When the cells were treated with a mixture of anionic lipids for 3 hours before the transfection, gene transfer yield was slightly decreased but the gene expression efficiency was enhanced by 1.9 times. This is presumably due to the accelerated liposome-plasmid dissociation by the anionic lipids, and the increased delivery of plasmid to the nucleus. According to these results, it is clear that the supplementation to ameliorate transfection efficiency with cationic liposomes should be contrived in the direction of increasing delivery of plasmid.

• 한국건축시공학회:학술대회논문집
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• 한국건축시공학회 2009년도 춘계 학술논문 발표대회 학계
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• pp.203-207
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• 2009

These days Construction Industry is one of the major industry in public project and it has many problems. And Construction Industry highly respond to a chage of IT, politics, economy, domestic and international situation. And it causes an uncertainty in Korea economy. The goal of this paper is showing the efficiency application of BIM in Public Project. And this paper follow three steps. First, these day's trend of BIM and delivery method are researched. Second, major factors are thrived to appreciating BIM Third, delivery method based on BIM is proposed. Major factors of delivery method are researched to make guide line of delivery method in public project in the future.

• Bulletin of the Korean Chemical Society
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• 제34권12호
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• pp.3665-3670
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• 2013

The R3V6 peptide includes a hydrophilic arginine stretch and a hydrophobic valine stretch. In previous studies, the R3V6 peptide was evaluated as a gene carrier and was found to have low cytotoxicity. However, the transfection efficiency of R3V6 was lower than that of poly-L-lysine (PLL) in N2A neuroblastoma cells. In this study, the transfection efficiency of R3V6 was improved in combination with high mobility group box 1A domain (HMGA). HMGA is originated from the nuclear protein and has many positively-charged amino acids. Therefore, HMGA binds to DNA via charge interaction. In addition, HMGA has a nuclear localization signal peptide and may increase the delivery efficiency of DNA into the nucleus. The ternary complex with HMGA, R3V6, and DNA was prepared and evaluated as a gene carrier. First, the HMGA/DNA complex was prepared with a negative surface charge. Then, R3V6 was added to the complex to coat the negative charges of the HMGA/DNA complex, forming the ternary complex of HMGA, R3V6, and DNA. A physical characterization study showed that the ternary complex was more stable than the PLL/DNA complex. The HMGA/R3V6/DNA complex had a higher transfection efficiency than the PLL/DNA, HMGA/DNA, or R3V6/DNA complexes in N2A cells. Furthermore, the HMGA/R3V6/DNA complex was not toxic to cells. Therefore, the HMGA/R3V6/DNA complex may be a useful gene delivery carrier.

• 한국건축시공학회:학술대회논문집
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• 한국건축시공학회 2013년도 춘계 학술논문 발표대회
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• pp.265-267
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• 2013

Recently, It is being reduction to market of the domestic construction industry for the instability of the domestic market structure. So it is necessary to plan response measures for to ensure the competitiveness of the construction market of overseas. The purpose of the study is suggest of improvement of the project delivery system for the efficiency of the construction of the unit modular housing of considering the reducing cost and technological competitiveness of the domestic construction industry.

• 유통과학연구
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• 제22권9호
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• pp.85-95
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• 2024

Purpose: Online food delivery platforms face challenges to operational efficiency due to increasing demand, a shortage of drivers, and the constraint of a one-order-at-a-time delivery policy. It is imperative to find solutions to address the inefficiencies in the food delivery industry. Bundling multiple orders can help resolve these issues, but it requires complex computations due to the exponential increase in possible order combinations. Research design, data and methodology: This study proposes three bundle delivery systems-static, dynamic, and hybrid-utilizing a machine learning-based classification model to reduce the number of order combinations for efficient bundle computation. The proposed systems are analyzed through simulations using market data from South Korea's online food delivery platforms. Results: Our findings indicate that implementing bundle systems extends service coverage to more customers, increases average driver earnings, and maintains lead times comparable to standalone deliveries. Additionally, the platform experiences higher service completion rates and increased profitability. Conclusions: This suggests that bundle systems are cost-effective and beneficial for all stakeholders in online food delivery platforms, effectively addressing the inefficiencies in the industry.

• Molecules and Cells
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• 제25권4호
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• pp.462-466
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• 2008

Adenoviruses are the most commonly used gene-delivery vectors due to the efficiency of their in vivo gene transfer. Since 1993, about 300 protocols using an adenoviral vector have been performed, although they have yet to be proven effective in clinical trials. The adenovirus-based vector has been continuously improved by modification of the adenoviral genome and capsid, and novel adenovirus-delivery systems, such as the carrier-cell delivery system, have been recently proposed. Adenovirus-based cancer gene therapy is fast becoming one component of a multi-modality treatment approach to advanced cancer, along with surgery, radiotherapy, and chemotherapy.