• 한국지능시스템학회논문지
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• 제15권2호
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• pp.211-223
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• 2005

오늘날의 소프트웨어 개발 형태는 CBD(Component Based Development)를 기초로 한다. 그러나 CBD를 이용하여 새로운 컴포넌트를 구축하기 위해서는 많은 비용으로 인해, 저비용의 빠르고 정확한 컴포넌트 정보를 웹상에서 지원할 수 있는 컴포넌트 모델이 요구되고 있다. 본 논문에서는 사용자의 요구사항을 충족하는 애플리케이션을 웹상에서 신속하게 개발하는데 목적을 두고 있으며, 네트워크상에서 비즈니스 도메인을 기반으로 한 가장 소규모 단위의 분산 컴포넌트를 대상으로 인터페이스 명세를 제공하고자 한다. e-BCOS(e-Business Component System)은 사용자가 분산 컴포넌트를 등록하고 검색할 수 있는 에이전트 시스템으로서 재사용성을 증대시키고 사용자가 쉽게 컴포넌트에 관한 정보를 얻고 이해할 수 있도록 해준다. 또한 명세의 공유와 유통을 원활히 하기 위해서 XML(eXtensible Markup Language)로 명세를 표현하여 사용자의 다양한 욕구를 충족시키도록 한다.

• 한국건설관리학회:학술대회논문집
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• 한국건설관리학회 2004년도 제5회 정기학술발표대회 논문집
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• pp.242-245
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• 2004

공공 건설사업 발주 정책의 변화 및 대형화, 복잡화되고 있는 건축 프로젝트의 특성에 따라 향후 건설시장은 디자인 빌드 방식의 건설사업이 더욱 증가할 것으로 예상된다. 그러나 디자인 빌드의 증가와 더불어 운영관리 측면에서의 문제점이 나타나고 있다. 디자인 빌드 방식은 일괄사업자가 설계와 시공에 대한 책임을 전담하게 되므로 많은 리스크 요인이 존재하며, 기본설계에서 실시설계를 거쳐 시공단계에 이르는 업무 프로세스가 명확히 규명되어 있지 않아 사업의 진행에 따른 사업 수행자의 일관되고 체계적인 관리가 어려운 실정이다. 이에 본 연구에서는 디자인 빌드 프로젝트의 효과적인 수행을 위한 프로세스 모델을 개발하고, 관련지식의 체계적인 축적 및 활용을 위한 데이터베이스의 구축방안을 제시하고자 한다.

• 대한인간공학회지
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• 제33권5호
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• pp.407-422
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• 2014

Objective: The purpose of the study is to develop quantitative usability evaluation criteria for senior-friendly autonomous transportation robot. Background: The Republic of Korea has become the most rapidly aging society, and is anticipated to enter the post-aged society in 2026. To raise the quality of life of a senior with limited mobility and to reduce the burden of caregivers, many high-tech assistive products with information technologies are developed nowadays. The senior-friendly autonomous transportation robot is one person robot vehicle to move a senior to the destination for hospitals, nursing homes or silver town complex. With built-in navigation system and environmental monitoring censors, it automatically seeks the path to the destination and avoids collision to obstacles and pedestrians on the way. Due to the early stage of the product, few usability studies in this field have been done, mostly on general service robots to assist seniors, power wheelchairs and delivery robots. ISO and KS standards for the service robots are focused on safety. Method: Based on the reference usability index, the early draft of the usability evaluation questionnaires was developed. After small group tests and interviews, the experts modified the initial draft to the Usability Evaluation Criteria for Senior-Friendly Autonomous Transportation Robot (UEC-SFATR). Result: UEC-SFATR consisted of 4 subscales - Safety, Controllability, Efficiency and Satisfaction. All of the 4 subscales of UEC-SFATR were passed the reliability criteria by 4 groups of seniors, divided by gender and familiarity of smart-devices. Conclusion: UEC-SFATR covers wider area of user experiences of the SFATR and is a good measurement tool to help both the users and developers of the robot. Application: This study provides guide to the future product development and product competitiveness evaluation by quantifying user experiences for the SFATR.

• Biomolecules & Therapeutics
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• 제25권4호
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• pp.411-416
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• 2017

Paclitaxel (PTX) is a effectively chemotherapeutic agent which is extensively able to treat the non-small cell lung, pancreatic, breast and other cancers. But it is a practically insoluble drug with water solubility less than $1{\mu}g/mL$, which restricts its therapeutic application. To overcome the problem, hyaluronic acid-complexed paclitaxel nanoemulsions (HPNs) were prepared by ionic complexation of paclitaxel (PTX) nanoemulsions and hyaluronic acid (HA) to specifically target non-small cell lung cancer. HPNs were composed of ${\small{DL}}-{\alpha}$-tocopheryl acetate, soybean oil, polysorbate 80, ferric chloride, and HA and fabricated by high-pressure homogenization. The HPNs were $85.2{\pm}7.55nm$ in diameter and had a zeta potential of $-35.7{\pm}0.25mV$. The encapsulation efficiency was almost 100%, and the PTX content was 3.0 mg/mL. We assessed the in vivo antitumor efficacy of the HPNs by measuring changes in tumor volume and body weight in nude mice transplanted with CD44-overexpressing NCI-H460 xenografts and treated with a bolus dose of saline, $Taxol^{(R)}$, PTX nanoemulsions (PNs), or HPNs at a dose of 25 mg/kg. Suppression of cancer cell growth was higher in the PN- and HPN-treated groups than in the $Taxol^{(R)}$ group. In particular, HPN treatment dramatically inhibited tumor growth, likely because of the specific tumor-targeting affinity of HA for CD44-overexpressed cancer cells. The loss of body weight and organ weight did not vary significantly between the groups. It is suggest that HPNs should be used to effective nanocarrier system for targeting delivery of non-small cell lung cancer overexpressing CD44 and high solubilization of poorly soluble drug.

• The Plant Pathology Journal
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• 제24권1호
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• pp.67-73
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• 2008

Seedling damping-off and bottom rot caused by Rhizoctonia solani are yield limiting diseases of crisphead lettuce. To provide biocontrol measure in the management of the diseases, biocontrol strain Pseudomonas aeruginosa LY-11 was isolated from lettuce rhizosphere and introduced into crisphead lettuce rhizosphere by the seed coating delivery method. Alginate was used as a coating material to generate beads containing $10^6-10^{6.5}$ colony-forming units (CFUs) of viable bacterial cells of LY-11. When seeds germinated from the alginate beads containing the strain LY-11, the bacteria established mostly in plant rhizosphere to maintain at least $10^4$ CFU per gram of plant tissues. Crisphead lettuce seedlings germinated from the entrapped seeds were less affected from damping-off and bottom rot with disease control values of 70.4% and 85.4% respectively. Although P. aeruginosa LY-11 colonized plant rhizosphere and not phyllosphere, the result indicated that bottom rot caused by the foliar inoculation of R. solani was effectively reduced by the rhizobacteria. All data suggested that immobilized rhizobacterial application in seeds by alginate coating could control damping-off and induce induced systemic resistance of crisphead lettuce to reduce bottom rot.

• 대한핵의학회지
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• 제32권1호
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• pp.99-108
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• 1998

Intraperitoneal administration of radioisotopes is suggested to treat the metastatic ovarian cancer in the peritoneal cavity. Administering beta-emitting radioisotopes into the peritoneal cavity allows the maximum energy delivery to the cancerous cells of the peritoneal wall surface while sparing the normal cells located in deep site of the peritoneal wall. In this study, dose estimates of the peritoneal wall are provided to be used for prescribing the amount of $^{166}Ho$-chitosan complex administered. The $^{166}Ho$-chitosan complex diffused in the peritoneal fluid may attach to the peritoneal wall surface. The attachment fraction of $^{166}Ho$-chitosan complex to the peritoneal wall surface is obtained by simulating the ascites with Fischer rats. Both volume source in the peritoneal fluid and the surface source over the peritoneal wall surface are counted for the contribution to the peritoneal wall dose. The Monte Carlo code EGS4 is used to simulate the energy transfer of the beta particles emitted from $^{166}Ho$. A plane geometrical model of semi-infinite volume describes the peritoneal cavity and the peritoneal wall. A semi-infinite plane of $10{\mu}m$ in thickness at every 1 mm of depth in the peritoneal wall is taken as the target in dose estimation. Greater than 98 percents of attachment fraction has been observed from the experiments with Fischer rats. Given $1.3{\mu}Ci/cm^2$ and $2.4{\mu}Ci/ml$ of uniform activity density, absorbed dose is 123 Gy, 8.59 Gy, 3.00 Gy, 1.03 Gy, and .327 Gy at 0 mm, 1 mm, 2 mm, 3 mm, and 4 mm in depth to the peritoneal wall, respectively.

• Asian-Australasian Journal of Animal Sciences
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• 제15권11호
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• pp.1659-1676
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• 2002

Ruminant animals develop a diverse and sophisticated microbial ecosystem for digesting fibrous feedstuffs. Plant cell walls are complex and their structures are not fully understood, but it is generally believed that the chemical properties of some plant cell wall compounds and the cross-linked three-dimensional matrix of polysaccharides, lignin and phenolic compounds limit digestion of cell wall polysaccharides by ruminal microbes. Three adaptive strategies have been identified in the ruminal ecosystem for degrading plant cell walls: production of the full slate of enzymes required to cleave the numerous bonds within cell walls; attachment and colonization of feed particles; and synergetic interactions among ruminal species. Nonetheless, digestion of fibrous feeds remains incomplete, and numerous research attempts have been made to increase this extent of digestion. Exogenous fibrolytic enzymes (EFE) have been used successfully in monogastric animal production for some time. The possibility of adapting EFE as feed additives for ruminants is under intensive study. To date, animal responses to EFE supplements have varied greatly due to differences in enzyme source, application method, and types of diets and livestock. Currently available information suggests delivery of EFE by applying them to feed offers the best chance to increase ruminal digestion. The general tendency of EFE to increase rate, but not extent, of fibre digestion indicates that the products currently on the market for ruminants may not be introducing novel enzyme activities into the rumen. Recent research suggests that cleavage of esterified linkages (e.g., acetylesterase, ferulic acid esterase) within the plant cell wall matrix may be the key to increasing the extent of cell wall digestion in the rumen. Thus, a crucial ingredient in an effective enzyme additive for ruminants may be an as yet undetermined esterase that may not be included, quantified or listed in the majority of available enzyme preparations. Identifying these pivotal enzyme(s) and using biotechnology to enhance their production is necessary for long term improvements in feed digestion using EFE. Pretreating fibrous feeds with alkali in addition to EFE also shows promise for improving the efficacy of enzyme supplements.

• 한국컴퓨터정보학회논문지
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• 제20권4호
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• pp.87-93
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• 2015

최근에 사용자 스스로가 네트워크를 구축하여 자신이 소유한 AP의 일부 대역폭을 다른 사람과 공유하는 방법이 대두되었는데 이러한 네트워크를 공유 네트워크라 한다. 응용 애플리케이션으로 공유 네트워크에서 SVC 기술을 사용하는 비디오 스트리밍 전송 시스템을 구축하는 방안이 제안되었는데, 서버로부터 클라이언트에게 비디오 스트림을 보내기 위해서는 루트는 서버이고 내부노드는 공유 AP이며 리프는 클라이언트인 트리 구조를 만들게 된다. 기존의 연구들은 공유 AP의 공유대역폭의 합을 최소로 사용해서 모든 클라이언트를 서비스하는 최소 공유대역폭 트리를 구축하는데 주안점을 두고 있다. 본 논문에서는 공유 AP들의 집합이 주어졌을 때 클라이언트의 비디오 스트림 요구를 최대로 만족시키는 최대 요구대역폭 트리를 구축하는 문제가 NP-하드임을 증명하였다. 또 이 문제를 해결하기 위한 효율적인 휴리스틱 알고리즘을 개발하고, 실험을 통해 성능을 평가하였다.

• 인터넷정보학회논문지
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• 제15권1호
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• pp.45-53
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• 2014

UI-Mashup은 웹 응용프로그램 개발의 최신 경향 중 하나로 인터넷 상에 분산된 다양한 콘텐츠를 조합하여 가치를 추가해 서비스하는 방안으로 널리 사용되고 있다. 현재까지 UI-Mashup 관련 연구는 동적 서비스 조합에 초점이 맞추어져 있고 급변하는 웹 표준에 적응하지 못하여 최종 사용자 입장에서 UI-Mashup은 느리고 불편하며 보안에 취약한 서비스로 인식되고 있다. 본 연구에서는 UI-Mashup의 성능 향상을 위한 아키텍처를 제안한다. 제안한 아키텍처는 빠른 서비스 제공과 보안 강화를 위해 UI조각을 서버에서 병렬로 수집하고 매쉬업된 UI의 레이아웃과 UI조각들을 별도의 전송 채널을 통해 클라이언트로 전송하여 빠른 반응시간과 응답시간을 제공한다. 본 연구에서는 제안한 아키텍처를 실증적으로 검증하기 위해 구현하였으며 성능테스트를 진행하였다. 성능테스트 결과 제안한 아키텍처는 기존 UI-Mashup 기법에 비해 2 ~ 3배 빠른 응답시간을 기록하였고, 4배이상의 처리량을 보였다.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제11권7호
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• pp.3309-3328
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• 2017

The application of Internet of Things (IoT) in the next generation cellular networks imposes a new characteristic on the data traffic, where a massive number of small packets need to be transmitted. In addition, some emerging IoT-based emergency services require a real-time data delivery within a few milliseconds, referring to as ultra-low latency transmission. However, current techniques cannot provide such a low latency in combination with a mice-flow traffic. In this paper, we propose a dynamic resource reservation schema based on an air-interface slicing scheme in the context of a massive number of sensors with emergency flows. The proposed schema can achieve an air-interface latency of a few milliseconds by means of allowing emergency flows to be transported through a dedicated radio connection with guaranteed network resources. In order to schedule the delay-sensitive flows immediately, dynamic resource updating, silence-probability based collision avoidance, and window-based re-transmission are introduced to combine with the frame-slotted Aloha protocol. To evaluate performance of the proposed schema, a probabilistic model is provided to derive the analytical results, which are compared with the numerical results from Monte-Carlo simulations.