• Journal of the Korean Institute of Intelligent Systems
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• v.15 no.2
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• pp.211-223
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• 2005

The current software development type is based on CBD (Component Based Development). However, it requires a new component model that can support rapid and accurate component information on the web due to the cost increase of building new components using CBD. The purposed of this paper is to promptly develop an application on the web which fulfills users' demand and to provide specific interface regarding the small scales of distributed component in business domains. The e-BCOS(e-Business Component System) is the agent system for the users to register distributed components and to search component information, which would increase reusability through the e-business component development of distributed components in business domains and help the users understand the information about the component. Moreover, XML is employed for specification which allows smooth specification sharing and delivery to satisfy users' variable demands.

• Proceedings of the Korean Institute Of Construction Engineering and Management
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• 2004.11a
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• pp.242-245
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• 2004

Recently, the design-build delivery system is being generalized in domestic construction project. The design-build system is becoming an increasingly preferable alterative to design-bid-build delivering method. In design-build project, however, a large construction company and design firm make up consortium as a design-build contractor rather than single company performs design and construction work. In this case, usually the construction companies take a leading role but due to their lack of managerial know-how in the design-build system, they could miss the merits of this approach. Therefore, it is necessary to investigated throughly the function and information flows all over the design-build project. In this research suggests a process model and database in the whole phase of design-build project. This process model and database system will also support to Improve the consistency of functional process and minimize incoherent activities in each phase of design-build project.

• Journal of the Ergonomics Society of Korea
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• v.33 no.5
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• pp.407-422
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• 2014

Objective: The purpose of the study is to develop quantitative usability evaluation criteria for senior-friendly autonomous transportation robot. Background: The Republic of Korea has become the most rapidly aging society, and is anticipated to enter the post-aged society in 2026. To raise the quality of life of a senior with limited mobility and to reduce the burden of caregivers, many high-tech assistive products with information technologies are developed nowadays. The senior-friendly autonomous transportation robot is one person robot vehicle to move a senior to the destination for hospitals, nursing homes or silver town complex. With built-in navigation system and environmental monitoring censors, it automatically seeks the path to the destination and avoids collision to obstacles and pedestrians on the way. Due to the early stage of the product, few usability studies in this field have been done, mostly on general service robots to assist seniors, power wheelchairs and delivery robots. ISO and KS standards for the service robots are focused on safety. Method: Based on the reference usability index, the early draft of the usability evaluation questionnaires was developed. After small group tests and interviews, the experts modified the initial draft to the Usability Evaluation Criteria for Senior-Friendly Autonomous Transportation Robot (UEC-SFATR). Result: UEC-SFATR consisted of 4 subscales - Safety, Controllability, Efficiency and Satisfaction. All of the 4 subscales of UEC-SFATR were passed the reliability criteria by 4 groups of seniors, divided by gender and familiarity of smart-devices. Conclusion: UEC-SFATR covers wider area of user experiences of the SFATR and is a good measurement tool to help both the users and developers of the robot. Application: This study provides guide to the future product development and product competitiveness evaluation by quantifying user experiences for the SFATR.

• Biomolecules & Therapeutics
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• v.25 no.4
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• pp.411-416
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• 2017

Paclitaxel (PTX) is a effectively chemotherapeutic agent which is extensively able to treat the non-small cell lung, pancreatic, breast and other cancers. But it is a practically insoluble drug with water solubility less than $1{\mu}g/mL$, which restricts its therapeutic application. To overcome the problem, hyaluronic acid-complexed paclitaxel nanoemulsions (HPNs) were prepared by ionic complexation of paclitaxel (PTX) nanoemulsions and hyaluronic acid (HA) to specifically target non-small cell lung cancer. HPNs were composed of ${\small{DL}}-{\alpha}$-tocopheryl acetate, soybean oil, polysorbate 80, ferric chloride, and HA and fabricated by high-pressure homogenization. The HPNs were $85.2{\pm}7.55nm$ in diameter and had a zeta potential of $-35.7{\pm}0.25mV$. The encapsulation efficiency was almost 100%, and the PTX content was 3.0 mg/mL. We assessed the in vivo antitumor efficacy of the HPNs by measuring changes in tumor volume and body weight in nude mice transplanted with CD44-overexpressing NCI-H460 xenografts and treated with a bolus dose of saline, $Taxol^{(R)}$, PTX nanoemulsions (PNs), or HPNs at a dose of 25 mg/kg. Suppression of cancer cell growth was higher in the PN- and HPN-treated groups than in the $Taxol^{(R)}$ group. In particular, HPN treatment dramatically inhibited tumor growth, likely because of the specific tumor-targeting affinity of HA for CD44-overexpressed cancer cells. The loss of body weight and organ weight did not vary significantly between the groups. It is suggest that HPNs should be used to effective nanocarrier system for targeting delivery of non-small cell lung cancer overexpressing CD44 and high solubilization of poorly soluble drug.

• The Plant Pathology Journal
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• v.24 no.1
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• pp.67-73
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• 2008

Seedling damping-off and bottom rot caused by Rhizoctonia solani are yield limiting diseases of crisphead lettuce. To provide biocontrol measure in the management of the diseases, biocontrol strain Pseudomonas aeruginosa LY-11 was isolated from lettuce rhizosphere and introduced into crisphead lettuce rhizosphere by the seed coating delivery method. Alginate was used as a coating material to generate beads containing $10^6-10^{6.5}$ colony-forming units (CFUs) of viable bacterial cells of LY-11. When seeds germinated from the alginate beads containing the strain LY-11, the bacteria established mostly in plant rhizosphere to maintain at least $10^4$ CFU per gram of plant tissues. Crisphead lettuce seedlings germinated from the entrapped seeds were less affected from damping-off and bottom rot with disease control values of 70.4% and 85.4% respectively. Although P. aeruginosa LY-11 colonized plant rhizosphere and not phyllosphere, the result indicated that bottom rot caused by the foliar inoculation of R. solani was effectively reduced by the rhizobacteria. All data suggested that immobilized rhizobacterial application in seeds by alginate coating could control damping-off and induce induced systemic resistance of crisphead lettuce to reduce bottom rot.

• The Korean Journal of Nuclear Medicine
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• v.32 no.1
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• pp.99-108
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• 1998

Intraperitoneal administration of radioisotopes is suggested to treat the metastatic ovarian cancer in the peritoneal cavity. Administering beta-emitting radioisotopes into the peritoneal cavity allows the maximum energy delivery to the cancerous cells of the peritoneal wall surface while sparing the normal cells located in deep site of the peritoneal wall. In this study, dose estimates of the peritoneal wall are provided to be used for prescribing the amount of $^{166}Ho$-chitosan complex administered. The $^{166}Ho$-chitosan complex diffused in the peritoneal fluid may attach to the peritoneal wall surface. The attachment fraction of $^{166}Ho$-chitosan complex to the peritoneal wall surface is obtained by simulating the ascites with Fischer rats. Both volume source in the peritoneal fluid and the surface source over the peritoneal wall surface are counted for the contribution to the peritoneal wall dose. The Monte Carlo code EGS4 is used to simulate the energy transfer of the beta particles emitted from $^{166}Ho$. A plane geometrical model of semi-infinite volume describes the peritoneal cavity and the peritoneal wall. A semi-infinite plane of $10{\mu}m$ in thickness at every 1 mm of depth in the peritoneal wall is taken as the target in dose estimation. Greater than 98 percents of attachment fraction has been observed from the experiments with Fischer rats. Given $1.3{\mu}Ci/cm^2$ and $2.4{\mu}Ci/ml$ of uniform activity density, absorbed dose is 123 Gy, 8.59 Gy, 3.00 Gy, 1.03 Gy, and .327 Gy at 0 mm, 1 mm, 2 mm, 3 mm, and 4 mm in depth to the peritoneal wall, respectively.

• Asian-Australasian Journal of Animal Sciences
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• v.15 no.11
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• pp.1659-1676
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• 2002

Ruminant animals develop a diverse and sophisticated microbial ecosystem for digesting fibrous feedstuffs. Plant cell walls are complex and their structures are not fully understood, but it is generally believed that the chemical properties of some plant cell wall compounds and the cross-linked three-dimensional matrix of polysaccharides, lignin and phenolic compounds limit digestion of cell wall polysaccharides by ruminal microbes. Three adaptive strategies have been identified in the ruminal ecosystem for degrading plant cell walls: production of the full slate of enzymes required to cleave the numerous bonds within cell walls; attachment and colonization of feed particles; and synergetic interactions among ruminal species. Nonetheless, digestion of fibrous feeds remains incomplete, and numerous research attempts have been made to increase this extent of digestion. Exogenous fibrolytic enzymes (EFE) have been used successfully in monogastric animal production for some time. The possibility of adapting EFE as feed additives for ruminants is under intensive study. To date, animal responses to EFE supplements have varied greatly due to differences in enzyme source, application method, and types of diets and livestock. Currently available information suggests delivery of EFE by applying them to feed offers the best chance to increase ruminal digestion. The general tendency of EFE to increase rate, but not extent, of fibre digestion indicates that the products currently on the market for ruminants may not be introducing novel enzyme activities into the rumen. Recent research suggests that cleavage of esterified linkages (e.g., acetylesterase, ferulic acid esterase) within the plant cell wall matrix may be the key to increasing the extent of cell wall digestion in the rumen. Thus, a crucial ingredient in an effective enzyme additive for ruminants may be an as yet undetermined esterase that may not be included, quantified or listed in the majority of available enzyme preparations. Identifying these pivotal enzyme(s) and using biotechnology to enhance their production is necessary for long term improvements in feed digestion using EFE. Pretreating fibrous feeds with alkali in addition to EFE also shows promise for improving the efficacy of enzyme supplements.

• Journal of the Korea Society of Computer and Information
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• v.20 no.4
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• pp.87-93
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• 2015

Recently, an idea has been suggested in which members construct the network by sharing their surplus bandwidth of their own access point. This kind of network is called public-shared network. As an application, SVC video streaming delivery system on public-shared network has been proposed. To send video stream from the stream server to clients, a tree structure is constructed where the root is a stream server, internal nodes are sharable access points, and leafs are clients. The previous researches have focused on constructing the minimal sharable-bandwidth tree which can serve all video streaming requests using the minimal sharable bandwidth. In this paper, we have shown that the problem of constructing a tree structure with given sharable access points to serve maximal video streaming requests is NP-hard. We also have developed an efficient heuristic algorithm for this problem and evaluated experimentally our algorithm.

• Journal of Internet Computing and Services
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• v.15 no.1
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• pp.45-53
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• 2014

UI-Mashup is widely used as a service method to add value, which is composed of distributed various contents on the internet and has turned out to be one of the latest trends in web application program development. Previous UI-Mashup-related studies have focused primarily on the dynamic service composition and have not been able to adapt to a rapidly changing Web Standard, thusthe end users conclude that UI-Mashups are slow, incompatible and poor security services. In this study, We propose an architecture for the performance improvements of UI-Mashup.In order to provide fast services and security enhancements, the proposed architecture collects UI fragments on the server in parallel, and sends layouts and contents of Mashups UI to the client through a special delivery channel supporting fast reaction and response time. In this study, the implementation and performance tests were proceeded to verify the proposed architecture experimentally. As a result of the performance testing, the proposed architecture has two to three times faster response time and more than four times throughput compared to the previous UI-Mashup technology.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.11 no.7
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• pp.3309-3328
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• 2017

The application of Internet of Things (IoT) in the next generation cellular networks imposes a new characteristic on the data traffic, where a massive number of small packets need to be transmitted. In addition, some emerging IoT-based emergency services require a real-time data delivery within a few milliseconds, referring to as ultra-low latency transmission. However, current techniques cannot provide such a low latency in combination with a mice-flow traffic. In this paper, we propose a dynamic resource reservation schema based on an air-interface slicing scheme in the context of a massive number of sensors with emergency flows. The proposed schema can achieve an air-interface latency of a few milliseconds by means of allowing emergency flows to be transported through a dedicated radio connection with guaranteed network resources. In order to schedule the delay-sensitive flows immediately, dynamic resource updating, silence-probability based collision avoidance, and window-based re-transmission are introduced to combine with the frame-slotted Aloha protocol. To evaluate performance of the proposed schema, a probabilistic model is provided to derive the analytical results, which are compared with the numerical results from Monte-Carlo simulations.