• Journal of Ginseng Research
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• v.39 no.2
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• pp.116-124
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• 2015

Background: Ginseng, the root of Panax ginseng (PG), is used widely as a herbal medicine to prevent and treat various diseases. Panax ginseng has pharmacological effects on neurodegenerative diseases such as Alzheimer's disease (AD). The present study evaluated the neuroprotective effects of PG and its possible neuroprotective mechanisms in advanced glycation end product (AGE)-induced AD in a rat model. Methods: Advanced glycation end products were injected bilaterally into the CA3 region of the rats' brains. The Morris water maze test and step-down type passive avoidance test were performed to evaluate their memory and cognitive abilities. The oxidation indexes in the hippocampus were detected. Immunohistochemistry was conducted to visualize the receptors for advanced glycation end products (RAGEs) and nuclear factor-kappa-light-chain-enhancer of activated B cell (NF-${\kappa}B$). Results: Behavioral results showed that PG (1 g/kg, 0.5 g/kg, and 0.25 g/kg) significantly shortened the escape latency, remarkably increased the number of crossing times, significantly decreased the number of errors, and prolonged the latency in rats with AGE-induced AD. Panax ginseng also significantly reduced the malondialdehyde level, increased the glutathione content, and increased superoxide dismutase activity in the hippocampus. Panax ginseng significantly decreased the expression of RAGE and NF-${\kappa}B$. The blockade of anti-RAGE antibody could significantly reduce AGE-induced impairments and regulate these expressions. Conclusion: Our results demonstrated that PG significantly inhibits AGE-induced memory impairment and attenuates Alzheimer-like pathophysiological changes. These neuroprotective effects of PG may be associated with the RAGE/NF-${\kappa}B$ pathway. Our results provided the experimental basis for applying PG in preventing and treating AD.

• Journal of Biosystems Engineering
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• v.16 no.2
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• pp.159-166
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• 1991

A simulation model was developed for analyzing a crop transport system using SLAMSYSTEM. The developed model could predict total delivered amount and delivery rate of a crop under various conditions of transport and analyze the effects of work factors on the efficiency of the crop transport system. A simulation model was also developed to analyze a rice transport system based on the generalized model of the crop transport system.

• Journal of the military operations research society of Korea
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• v.13 no.1
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• pp.28-44
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• 1987

This thesis presents a model to assign targets and to determine gun ammunitions required for naval surface warfare. Delivery errors of weapon systems and vulnerability of moving targets are analyzed, then probability to kill moving battle sihps is computed. A weapon-target allocation model is proposed by using the Out of Kilter technique. A model to determine ammunitions required for killing moving targets is also designed. The models are evaluated by simulation and sensitivity analysis.

• The Journal of Society for e-Business Studies
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• v.21 no.2
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• pp.47-59
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• 2016

Parcel service is to deliver goods from one place to the designated destination requested according to user request. Parcel operations such as sorting, distributing, etc. or the managed information are heterogeneous by the companies. Additionally, it is impossible to support interoperability between companies with unformatted data of manual processing. Most parcel package boxes attached to paper typed waybill is attached is delivered to consignee. So, security problems such as personal information leaking are occurred, or extra processing time and logistics costs are needed due to wrong or the damaged information. Business environment of parcel service is rapidly changed as introducing unmanned delivery or the advanced technology such as Internet of Things. User want to know the accurate status or steps from parcel service request to delivery. To provide these requirements, the unified and integrated waybill information for reliable transportation of parcel service is needed. This information will provide to pickup or delivery carrier, warehouse or terminal, and parcel service user per pickup, transport, and delivery stage of parcel delivery service. Therefore, this paper defines the simplified and unified information model for parcel service waybill by analyzing information systems used for logistics unit processes that is occurred to parcel service, and manual work processes, and developing the relevant information of work flows occurred between business processes or transactions with the collected or processed information by from parcel service's stages. It is possible to share these standard model between business entities, and replacing paper typed waybill will improve national life safety as preventing security threats by paper typed waybill. As a result, it will promote the public interest from the stakeholder's perspective.

• Journal of Internet Computing and Services
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• v.19 no.1
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• pp.37-47
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• 2018

The number of capabilities of Internet of Things (IoT) devices will exponentially grow over the next years. These devices may generate a vast amount of time-constrained data. In the context of IoT, data management should act as a layer between the objects and devices generating the data and the applications accessing the data for analysis purposes and services. In addition, most of IoT services will be content-centric rather than host centric to increase the data availability and the efficiency of data delivery. IoT will enable all the communication devices to be interconnected and make the data generated by or associated with devices or objects globally accessible. Also, fog computing keeps data and computation close to end users at the edge of network, and thus provides a new breed of applications and services to end users with low latency, high bandwidth, and geographically distributed. In this paper, we propose Edge-Fog cloud-based Hierarchical Data Delivery ($EFcHD^2$) method that effectively and reliably delivers IoT data to associated with IoT applications with ensuring time sensitivity. The proposed $EFcHD^2$ method stands on basis of fully decentralized hybrid of Edge and Fog compute cloud model, Edge-Fog cloud, and uses information-centric networking and bloom filters. In addition, it stores the replica of IoT data or the pre-processed feature data by edge node in the appropriate locations of Edge-Fog cloud considering the characteristic of IoT data: locality, size, time sensitivity and popularity. Then, the performance of $EFcHD^2$ method is evaluated through an analytical model, and is compared to fog server-based and Content-Centric Networking (CCN)-based data delivery methods.

• Journal of Convergence for Information Technology
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• v.10 no.2
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• pp.39-48
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• 2020

Many studies have been conducted to analyze factors that affect customer satisfaction, and service quality improvement in the parcel delivery industry. Most of these studies have a limited number of respondents using methods such as surveys and interviews. Therefore, this study aims to supplement the shortcomings of previous studies, by searching and analyzing the common major topics related to the complaints pointed out by consumers and suppliers in the parcel delivery service with cases of consumer counseling, and articles that reflect the complaints of workers in the industry. In addition, by analyzing the trend of these topics, we attempted to discover new topics and suggest implications. In conclusion, topics such as delay/lost/wrong deliveries as well as the fierce competition in the parcel delivery industry, turned out to be central aspects. As a result of the topic trend analysis, talks with international couriers have recently increased, and many conflicts related to apartment parcel delivery have been dealt with. The topics presented in this study are mainly focused on the contents of previous studies, but we expect that new and valuable topics can be derived by adding other data and analysis methods, such as internal counseling and academic literature.

• Journal of Biomedical Engineering Research
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• v.40 no.2
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• pp.39-47
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• 2019

Ultrasound sonication along with microbubble (MB) could enhance drug delivery to promote the absorption of anticancer drugs into cancers in a noninvasive and targeted manners. In this study, we verify the acute drug delivery enhancement (within an hour) of two representative focused ultrasound driven drug delivery enhancement methods (MB and Doxorubicin-coated Nanoparticle complex (MB-NP) based). Experiments were conducted using in vivo mouse model with MDA-MB-231 breast cancer cell line. Ultrasound generated by single-element 1 MHz focused ultrasound transducer was delivered in pulsed sonication consisted of 0.125 msec bursts at a pulse repetition frequency of 2 Hz for 20 seconds without a significant increase in local temperature (less than $0.1^{\circ}C$) or hemorrhage. Doxorubicin concentrations in tumors were improved by 1.97 times in the case of MB-NP, and 1.98 times by using Doxorubicin and MB separately. These results indicate anticancer drug delivery based on MB and MB-NP can significantly improve the effect of anticancer drugs delivered to tumors in a short time period by using low-intensity focused ultrasound.

• Journal of Service Research and Studies
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• v.13 no.2
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• pp.1-23
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• 2023

In this study, we try to discover some success factors, for the entire value chain of the O2O food delivery industry in China, from ordering to delivery. We study the influence of three aspects of the value chain, namely, (1) the mobile platform, (2) the restaurant and food and (3) the delivery service, on the perceived value and repurchase intention of customers. Using structural equation modeling, we develop a structural research model with seven sets of hypotheses relating various independent variable constructs (platform, restaurant, and delivery) and dependent constructs (perceived value and repurchase intention). We find that usefulness of mobile app, the food condition and the availability of offline restaurants were significant antecedents for perceived value and repurchase intention. In addition, fair pricing was a significant antecedent for repurchase intention.

• Journal of the Korean Society for information Management
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• v.25 no.1
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• pp.61-74
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• 2008

The purpose of this study is to estimate economic value of document delivery services(DDS) at foreign journal supporting center in K University library. For this study, Bass diffusion model, which is widely used in forecasting, especially new product and new service forecasting, was adopted. User survey was also carried out from September 10 to 20, 2007. As a result, useful value(UV) of DDS is estimated about not less than 2,000,000,000 won, and willingness to pay(WTP) is estimated about less than 2,000,000,000 won. This study, economic value analysis at foreign journal supporting center, was limited to DDS, and used methodology for the study is also limited to UV and WTP. Demographic analysis(i.e., sex, age, occupation, educational level) for UV and WTP is also conducted.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.14 no.11
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• pp.5890-5896
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• 2013

This Study aimed at suggesting the plan for accumulating and utilizing schedule information of IFC file in BIM-based delivery system. For this Propose, First, literature review is conducted for analyzing utilization plan of schedule information and the IFC standard. Second, Schedule Planning process is analyzed to draw Schedule elements, and schedule information items is derived by analyzing schedule process and commercial software. Also, schedule elements in the IFC schema is derived by analyzing IFC schema through drawn schedule information. Finally, this study suggests a concept model accumulating and utilizing Schedule information included in IFC schema, and a conceptual delivery process of BIM model by analyzing BIM Application Guideline for Facility Project by PPS (Public Procurement Service) for accumulating IFC delivery files This study will expects to contribute to accumulate information of BIM model at the point of nationally introducing BIM.