• 한국미생물학회:학술대회논문집
• /
• 한국미생물학회 2002년도 추계학술대회
• /
• pp.109-115
• /
• 2002

Gene therapy is to treat and cure diseases by an introduction of therapeutic genes in defective cells or tissues of human body. Gene delivery system, gene expression system, and therapeutic gene are three core elements for gene therapy. The efficient delivery of therapeutic genes and appropriate gene expression are the crucial issues for therapeutic outcome of gene delivery. Because it can be used in common for the treatment and cure of various diseases, gene delivery system is the most important core element for a successful gene therapy. Viruses are naturally evolved to transfer their genomes into host cells efficiently. This ability has made vectorologists exploit viruses as attractive vehicles for the delivery of therapeutic genes. Viral vectors based on adenovirus (Ad) and adeno-associated virus (AAV) have been often used for gene delivery in laboratory. Ad and AAV vectors derived from human DNA viruses differ greatly in their life cycle, expression level and duration of transgenes, immunogenicity, and vector preparation. Both vectors can be used as effective tools for gene therapy and more recently in functional genomics. Here, the characteristics of Ad and AAV vectors are discussed.

• 대한안전경영과학회:학술대회논문집
• /
• 대한안전경영과학회 2010년도 춘계학술대회
• /
• pp.415-421
• /
• 2010

Door to door service is a typical method for individual parcel deliveries. In the current delivery information system, a delivery person manually input the information of many delivery results, which causes inefficiency and difficulties of tracking deliveries. This study suggests an enhanced delivery information system which has the following two characteristics. Firstly, a tagged RFID transmits the delivery result information to the main server by just collecting RFID at a place of destination. Secondly, with the characteristics of rewritable method, the collected RFID is to be input new information and tagged to other parcels.

• 한국생물물리학회:학술대회논문집
• /
• 한국생물물리학회 1996년도 정기총회 및 학술발표회
• /
• pp.37-37
• /
• 1996

Tenecin fragments are antimicrobial and antifungal peptide from Tenebrio molitor with highly positive charged amino acid residues. To elucidate their membrane selectivity and molecular mechanism, various forms of tenecin fragments were synthesized, and their interaction with acidic phospholipid, Gram (+), fungal and human erythrocyte membrane were investigated by ANTS/DPX leakage, membrane binding and fusion assay. (omitted)

• 산업공학
• /
• 제25권2호
• /
• pp.196-203
• /
• 2012

In the postal delivery service, both the standardization of business process and the workload measurement is very important part of saving the cost and improving the efficiency. However, these are not easy to apply to real situation because of the labor-intensive and diversification of delivery environment. In this study, we develop the methodology for the standardization of business process and workload measurement model of the postal delivery service. Firstly, we introduce the work factor analysis on the postal delivery process. Then, we propose the methodology workload measurement model based on diversification of delivery environment.

• 대한안전경영과학회지
• /
• 제12권2호
• /
• pp.107-112
• /
• 2010

Door to door service is a typical method for individual parcel deliveries. In the current delivery information system, a delivery person manually inputs the information of many delivery results, which causes inefficiency and difficulties of tracking deliveries. This study suggests an enhanced delivery information system which has the following two characteristics. Firstly, a tagged RFID(Radio Frequency Identification) transmits the delivery result information to the main server by just collecting RFID at a place of destination. Secondly, with the characteristics of rewritable method, the collected RFID is to be input new information and tagged to other parcels.

• 대한안전경영과학회지
• /
• 제13권3호
• /
• pp.97-105
• /
• 2011

In order to determine home delivery service routes, conditions specified for each parcel such as customer-assigned delivery times and parcel contents should be considered, so the conventional route search algorithms have some limits to be applied for home delivery services. In this study, a multi-purpose route searching algorithm is suggested in order to deal with every requirement of deliveries that vary in delivery distances, contents and appointed times. A simulation study to verify the performances of the system with example data of Seoul and Kyungki provinces shows that it significantly improves the customer satisfaction and the productivity of delivery businesses.

• Archives of Pharmacal Research
• /
• 제9권2호
• /
• pp.63-73
• /
• 1986

The use of biodegradable polymetric materials as drug carriers is a relatively new dimension in polymeric drug delivery systems. A number of biodegradable or bioerodible polymers, such as poly(lactic/glycolic acid) copolymer, poly($\alpha$-amino acid), polyanhydride, and poly (ortho ester) are currently being investigated for this purpose. These polymers are useful for matrix and reservoir-type delivery devices. In addition, when chemical functional groups are introduced to the biodegradable polymer backdone, such as poly (N-(2-hydroxypropyl) methacrylamide), the therapeutic agent can be covalently bound directly or via spacer to the backbone polymer. These polymer/drug conjugates represent another new dimension in biodegradable polymeric drug delivery systems. In addition, examples of biodegradable polymeric durg delivery systems currently being investigated will be discussed for the purpose of demonstrarting the potential importance of this new field.

• International Journal of Computer Science & Network Security
• /
• 제21권12spc호
• /
• pp.443-450
• /
• 2021

The study is devoted to the formation of a economic principles cargo delivery management in global supply chains. Mathematical model of delivering special categories of goods by road is a key element of these principles. The article analyzes the existing studies on solving the problem of cargo delivery in various aspects. It was noted that the greatest attention is paid to legal regulation, last mile delivery, optimization of routes and delivery schemes, information support, technological innovations, cluster routing, etc. In the developed mathematical model a minimum of total costs of forming loading units and freight shipments was defined as the criterion of optimality of organizing delivery by motor transport. The authors propose the creation of logistics clusters allowing the integration of urban transport flows and global supply chains.

• 한국정보시스템학회지:정보시스템연구
• /
• 제27권4호
• /
• pp.129-147
• /
• 2018

Purpose The purpose of this study is to identify the effects of users' perceived value of food delivery Apps and information quality on acceptance and intention to reuse of food delivery Apps. Design/methodology/approach This study made a design of the research model by integrating the factors of perceived value and information quality with the acceptance and continued usage of delivery Apps on the basis of the TAM (Technology Acceptance Model). Findings The results of this study suggests that perceived emotional value and monetary value, accuracy and timeliness of information have significant positive effects on usefulness and easiness of food delivery Apps. Meanwhile, both usefulness and easiness of food delivery Apps have significant positive influences on users' continually use intention. Furthermore, implications in terms of the findings of this study are discussed.

• Journal of Dairy Science and Biotechnology
• /
• 제36권4호
• /
• pp.187-195
• /
• 2018

Nano-delivery systems, such as nanoparticles, nanoemulsions, and nanoliposomes, are carriers that have been used to enhance the chemical as well as physical stability and bioavailability of bioactive compound. Food-grade nano-delivery system can be produced with edible biopolymers including proteins and carbohydrates. In addition to the low-toxicity, biocompatibility, and biodegradability of these biopolymers, their functional characteristics, such as their ability to bind hydrophobic bioactive compounds and form a gel, make them potential and ideal candidates for the fortification of bioactive compounds in functional dairy foods. This review focuses on different types of nano-delivery systems and edible biopolymers as delivery materials. In addition, the applications of food-grade nano-delivery systems to dairy foods are also described.