• Journal of the Korea Institute of Military Science and Technology
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• v.27 no.1
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• pp.116-125
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• 2024

The COVID-19 pandemic is not over despite the emergency use authorization as can see recent COVID-19 daily confirmed cases. The viruses are not only difficult to diagnose and treat due to random mutations, but also pose threat human being because they have the potential to be exploited as biochemical weapons by genetic manipulation. Therefore, it is inevitable to the rapid antibody-based therapeutic platform to quickly respond to future pandemics by new/re-emerging viruses. Although numerous researches have been conducted for the fast development of antibody-based therapeutics, it is sometimes hard to respond rapidly to new viruses because of complicated expression or purification processes for antibody production. In this study, a novel rapid antibody-based therapeutic platform using single B cell sorting method and mRNA-antibody. High immunogenicity was caused to produce antibodies in vivo through mRNA-antigen inoculation. Subsequently, antigen-specific antibody candidates were selected and obtained using isolation of B cells containing antibody at the single cell level. Using the antibody-based therapeutic platform system in this study, it was confirmed that novel antigen-specific antibodies could be obtained in about 40 days, and suggested that the possibility of rapid response to new variant viruses.

• Journal of Korea Technology Innovation Society
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• v.12 no.2
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• pp.312-334
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• 2009

Advanced countries including OECD member countries focus on the Open Innovation strategy to strengthen their national science and technology innovation capability and to promote the utilization of its outcome. Numerous relevant researches are proceeded in these days, however, just few researches exist in the defense science and technology innovation fields. Therefore, the paper tries to apply Open Innovation concept to the national defense science and technology fields based on the change of defense environments and its problems. For this reason, the paper also presents the theoretical framework of defense Open Innovation and future directions for the purpose of strengthening the national defense science and technology innovation capability and expanding its outcomes.

• Journal of Korean Society for Quality Management
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• v.49 no.1
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• pp.97-112
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• 2021

Purpose: The purpose of this paper is to analyze the technology convergence and its characteristics, focusing on the defense technologies in South Korea. Methods: Patents applied by the Agency for Defense Development (ADD) during 1979~2019 were utilized in this paper. Information Entropy analysis has been conducted on the patents to analyze the usability and potential for development. To analyze the trend of technology convergence in defense technologies, Social Network Analysis(SNA) and Association Rule Mining Analysis were applied to the co-occurrence networks of International Patent Classification (IPC) codes. Results: The results show that sensor, communication, and aviation technologies played a key role in recent development of defense science and technology. The co-occurrence network analysis also showed that the convergence has gradually enhanced over time, and the convergence between different technology sectors largely emerged, showing that the convergence has been diversified. Conclusion: By analyzing the patents of the defense technologies during the last 30 years, this study presents the comprehensive perspectives on trends and characteristics of technology convergence in defense industry. The results of this study are expected to be used as a guideline for decision making in the government's R&D policies in defence industry.

• Electronics and Telecommunications Trends
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• v.35 no.6
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• pp.56-67
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• 2020

The core technologies of the 4th Industrial Revolution, such as artificial intelligence, the Internet of Things, the cloud, big data, and mobile networks, are inspiring major changes and innovations in the defense sector worldwide. The United States, China, and Russia are pursuing defense research and development strategies that seek to maintain their leadership on the battlefield in the future through the overwhelming superiority of defense science technology. Defense science and technology concentrate on the development of challenging new disruptive technologies to efficiently respond to future battlefield environments, where the immediate process of determining the outcome of a war will lead to combat power. In this paper, we first look at the development strategies of the 4th Industrial Revolution in major countries and describe the latest trends in defense science and technology accordingly.

• Journal of the Korea Institute of Military Science and Technology
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• v.26 no.4
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• pp.335-343
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• 2023

Drone based Magnetic Anomaly Detection measure a magnetic anomaly signal from the ferromagnetic target on the ground. We conduct a magnetic anomaly detection with 9 ferromagnetic targets on the ground. By removing the magnetic field measured in the absence of ferromagnetic targets from the experimental value, the magnetic anomaly signal is clearly measured at an altitude of 100 m. We analyze the signal characteristics by the ferromagnetic target through simulation using COMSOL multiphysics. The simulation results are within the GPS error range of the experimental results.

• Molecules and Cells
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• v.26 no.2
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• pp.107-112
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• 2008

Invasion mechanisms of pathogens and counteracting defense mechanisms of plants are highly diverse and perpetually evolving. While most classical studies of plant defense have focused only on defense-specific factor-mediated responses, recent work is beginning to shed light on the involvement of non-stress signal components, especially growth and developmental processes. This shift in focus links plant resistance more closely with growth and development. In this review, we summarize our current understanding of how pathogens manipulate host developmental processes and, conversely, of how plants deploy their developmental processes for self-protection. We conclude by introducing our recent work on UNI, a novel R protein in Arabidopsis which mediates cross-talk between developmental processes and defense responses.

• Journal of the Korea Institute of Military Science and Technology
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• v.11 no.6
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• pp.117-126
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• 2008

Recently, the investment and importance have been increasing concerning the researches which are based on fundamental studies. In defense science and technology development, the defense research centers are involved in a large portion of developing the potential capability such as defense applied technology, enhanced human resource, etc. In this paper, we analyzed the relative efficiency of 9 research centers(9 DMU : Decision Making Unit) supported by the defense budget, using DEA(Date Envelopment Analysis) method especially with the CCR-I(Charnes, Cooper, Rhodes-Input) model. Some variables are selected such as budget(input data), patent, article and human resource(output data) to be analyzed. Conclusively, the needs to identify performance-indicators, increase incentives to promote the performance and induce enthusiastic participation in defense science and development projects, are suggested via a relative efficiency analysis.

• The Journal of the Convergence on Culture Technology
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• v.9 no.3
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• pp.293-298
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• 2023

In order for the military organization to be reborn as a high-tech science and technology strong force, science and technology that can be applied to the military is identified at the rapid development of science and technology, This should be quickly applied to military organizations, which is a growing consensus that Defense R&D planning system centered on rioters is needed to quickly acquire advanced weapons systems. In this respect, in order to successfully achieve the current government's defense policy, the high-tech weapons system necessary for national defense is required quicklyIt is necessary to closely examine defense planning, systems, organizations, and functions to develop into a high-tech science and technology military to link from raising to acquiring, and to reorganize the power enhancement and operation system. Therefore, this study proposes a high-efficiency defense operation system that combines advanced science and technology by Korean military organizations through "Defense Innovation 4.0", and we hope that follow-up research will be conducted following this study.

• Journal of the Korea Institute of Military Science and Technology
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• v.17 no.4
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• pp.492-500
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• 2014

The defense industry export of Korea has been steadily risen since 2006. It is attained $340million, the highest export amounts ever, in 2013. As the defense industry export increase, Defense Acquisition Program Administration (DAPA) built defense industry export and import management system to assist export and to protect defense technologies. In this paper, we study factors to activate the defense industry export and import management system using Technology Acceptance Model(TAM) in compulsive usage environment. The significance of this study is as follows: First, we prove the reliability and feasibility of measurement variables in defense industry of compulsive usage environment. Second, we suggest factors to activate the defense industry export and import management system. Third, we present methodology to find factors in computation systems of public institute using TAM.

• Nano
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• v.13 no.11
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• pp.1850126.1-1850126.10
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• 2018

Flexible strain sensors, as the core member of the family of smart electronic devices, along with reasonable sensing range and sensitivity plus low cost, have rose a huge consumer market and also immense interests in fundamental studies and technological applications, especially in the field of biomimetic robots movement detection and human health condition monitoring. In this paper, we propose a new flexible strain sensor based on thick CVD graphene film and its low-cost fabrication strategy by using the commercial adhesive tape as flexible substrate. The tensile tests in a strain range of ~30% were implemented, and a gage factor of 30 was achieved under high strain condition. The optical microscopic observation with different strains showed the evolution of cracks in graphene film. Together with commonly used platelet overlap theory and percolation network theory for sensor resistance modeling, we established an overlap destructive resistance model to analyze the sensing mechanism of our devices, which fitted the experimental data very well. The finding of difference of fitting parameters in small and large strain ranges revealed the multiple stage feature of graphene crack evolution. The resistance fallback phenomenon due to the viscoelasticity of flexible substrate was analyzed. Our flexible strain sensor with low cost and simple fabrication process exhibits great potential for commercial applications.