• Journal of the Optical Society of Korea
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• 제17권1호
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• pp.73-80
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• 2013

In the process of lithography using ultra violet light sources for semiconductor devices, most of defects are made by sub-micrometer pollutants generated at photochemical reactions. We proposed and developed a novel vibration-insensitive on-axis interferometer with a sub-micrometer lateral resolution by using the interference between two beams: one scattered from defects and the other reflected from a reference area without defects. The proposed system was successfully demonstrated to detect a small Al defect of 0.5 ${\mu}m$ diameter within the inspection time of less than 30 minutes over the area of the photo-mask which is 6 inch by 6 inch square.

• Clinical and Experimental Pediatrics
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• 제64권6호
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• pp.269-279
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• 2021

Clustered regularly interspaced short palindromic repeats and CRISPR-associated protein 9 (CRISPR-Cas9) is an ancient prokaryotic defense system that precisely cuts foreign genomic DNA under the control of a small number of guide RNAs. The CRISPR-Cas9 system facilitates efficient double-stranded DNA cleavage that has been recently adopted for genome editing to create or correct inherited genetic mutations causing disease. Congenital heart disease (CHD) is generally caused by genetic mutations such as base substitutions, deletions, and insertions, which result in diverse developmental defects and remains a leading cause of birth defects. Pediatric CHD patients exhibit a spectrum of cardiac abnormalities such as septal defects, valvular defects, and abnormal chamber development. CHD onset occurs during the prenatal period and often results in early lethality during childhood. Because CRISPR-Cas9-based genome editing technology has gained considerable attention for its potential to prevent and treat diseases, we will review the CRISPR-Cas9 system as a genome editing tool and focus on its therapeutic application for CHD.

• 한국기계가공학회지
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• 제20권8호
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• pp.60-66
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• 2021

This study aimed at identifying and optimizing the heating-condition parameters that cause surface defects during the compression molding of chalcogenide glass (GeSbSe) lenses through thermal analysis. We derived the optimal heating conditions for molding chalcogenide glass lenses through thermal analysis and analyzed the surface defects. As a result, we observed a significant reduction in surface defects, which verified the analysis process.

• Nuclear Engineering and Technology
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• 제54권8호
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• pp.2783-2791
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• 2022

Molecular dynamics simulations were performed to predict the behavior of graphite atoms under neutron irradiation using large-scale atomic/molecular massively parallel simulator (LAMMPS) package with adaptive intermolecular reactive empirical bond order (AIREBOM) potential. Defect structures of graphite were compared with results from previous studies by means of density functional theory (DFT) calculations. The quantitative relation between primary knock-on atom (PKA) energy and irradiation damage on graphite was calculated. and the effect of PKA direction on the amount of defects is estimated by counting displaced atoms. Defects are classified into four groups: structural defects, energy defects, vacancies, and near-defect structures, where a structural defect is further subdivided into six types by decision tree method which is one of the supervised machine learning techniques.

• 한국주조공학회지
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• 제41권6호
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• pp.521-527
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• 2021

본 연구는 고압 다이캐스팅 공정에서 제품 결함을 사전에 예측하기 위한 기계 학습 기반의 공정 관리 모델 개발에 관한 연구이다. 모델은 이전 사이클에서의 온도를 입력받고, 사이클에 걸쳐서 나타나는 특징을 인식하여 다음 사이클의 결함 발생 여부를 예측한다. 기어 박스 형상에 대하여 제안된 알고리즘을 적용하여, 3 사이클의 정보를 통해서 98 .9%의 정확도와 96.8 %의 재현율로 제품 수축 결함을 사전에 예측하였다.

• 한국전기전자재료학회논문지
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• 제35권5호
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• pp.419-430
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• 2022

Defects in solids play a vital role on thermoelectric properties through the direct impacts of electronic band structure and electron/phonon transports, which can improve the electronic and thermal properties of a given thermoelectric semiconductor. Defects in semiconductors can be divided into four different types depending on their geometric dimensions, and thus understanding the effects on thermoelectric properties of each type is of a vital importance. This paper reviews the recent advances in the various thermoelectric semiconductors through defect engineering focusing on the charge carrier and phonon behaviors. First, we clarify and summarize each type of defects in thermoelectric semiconductors. Then, we review the recent achievements in thermoelectric properties by applying defect engineering when introducing defects into semiconductor lattices. This paper ends with a brief discussion on the challenges and future directions of defect engineering in the thermoelectric field.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제42권
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• pp.15.1-15.8
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• 2020

Background: Reconstructing maxillofacial defects is quite challenging for most surgeons due to the region's complex anatomy and cosmetic and functional effects on patients. The use of pre-made alloplastic implants and autogenous grafts is often associated with resorption, infection, and displacement. Recent technological advances have led to the use of custom computer-designed patient-specific implants (PSIs) in reconstructive surgery. This study describes our experience with PSI, details the complications we faced, how to overcome them, and finally, evaluates patient satisfaction. Case presentation: Six patients underwent reconstruction of various maxillofacial defects arising due to different etiologies using PSI. A combined total of 10 implants was used. PEEK was used to fabricate 8, while titanium was used to fabricate 2. No complications were seen in any patient both immediately post-op and in subsequent follow-ups. All patients reported a high level of satisfaction with the final result both functionally and cosmetically. Conclusion: The use of computer-designed PSI enables a more accurate reconstruction of maxillofacial defects, eliminating the usual complications seen in preformed implants and resulting in higher patient satisfaction. Its main drawback is its high cost.

• 국제학술발표논문집
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• The 9th International Conference on Construction Engineering and Project Management
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• pp.213-221
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• 2022

Defects are the risk factors in the construction process of buildings. They cause damage, delaying the construction duration. They especially cause adverse effects on the top-down construction method. This study analyzed the degree of construction delay induced by each work type, focusing on defects in the top-down method. Then, we derived construction delay induction coefficient from different work types in order by using the severity of construction delay per defect and the occurrence probability of defect; this assessment model measures the impact of defects on construction delay for each work type. Furthermore, by comparing each work type based on the defect frequency and the construction delay induction coefficient, we found work types that need to be administered attentively. We identified that plastering work was easy to overlook, requiring caution in defect management. This study provides an efficient defect management system suitable for the buildings that are built using the top-down construction method.

• Archives of Plastic Surgery
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• 제50권1호
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• pp.82-95
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• 2023

Upper extremity reconstruction may pose clinical challenges for surgeons due to the often-critical, complex functional demands of the damaged and/or missing structures. The advent of vascularized bone grafts (VBGs) has aided in reconstruction of upper extremity (UE) defects due to their superior regenerative properties compared with nonvascularized bone grafts, ability to reconstruct large bony defects, and multiple donor site options. VBGs may be pedicled or free transfers and have the potential for composite tissue transfers when bone and soft tissue are needed. This article provides a comprehensive up-to-date review of VBGs, the commonly reported donor sites, and their indications for the treatment of specific UE defects.

• 한국건축시공학회:학술대회논문집
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• 한국건축시공학회 2022년도 봄 학술논문 발표대회
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• pp.29-30
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• 2022

Tile defects in apartment houses are caused by a combination of various factors. These factors cannot be specified, and it is difficult to determine the exact cause because a number of causes are intertwined. In addition, because the climate of Korea is different by season, the coefficient of thermal expansion between materials is different, which is a major cause of tile defects. Therefore, this study analyzed the difference between the construction location and the period of defect occurrence according to the types of tile defects caused by environmental differences between indoor and outdoor environments. Two-way ANOVA was used, indoor and outdoor spaces were selected, and defect types were selected accordingly to show the difference in the occurrence period of each defect.