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Parkinsonism after Cyanide Intoxication: A Case Report (시안화칼륨 중독으로 인해 발생한 파킨슨씨병 1례)

  • Suh, Joo-Hyun;Eo, Eun-Kyung
    • Journal of The Korean Society of Clinical Toxicology
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    • v.2 no.2
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    • pp.137-140
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    • 2004
  • Acute cyanide poisoning is usually the result of attempted suicide which is often lethal within minutes or leads to a very poor prognosis after delayed and inadequate treatment. It affects the cerebral structures with the highest oxygen requirement, such as the basal ganglia, the cerebral cortex. We experienced a-45-year-old man who ingested Potassium Cyanide. He was stuporous. In 25 minutes, respiratory arrest developed and cardiopulmonary resuscitation was done. After return of spontaneous circulation, he admitted to intensive care unit, and conservative treatment was started. The clinical status was improved by degrees, but he couldn't perform daily activity like before. Minimal limitation of movement and memory deficit were left. In magnetic resonance imaging, which taken at the 11th day after admission, there were both basal ganglia and folia of cerebellum abnormality.

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A Study on the Characteristics of Pine-tree Mushroom(Tricholoma matsutake Sing.) Pickle for the Standard Recipe (냉동 자연 송이버섯의 피클 조리법 표준화를 위한 연구)

  • Park, Mi-Lan
    • Culinary science and hospitality research
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    • v.14 no.4
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    • pp.55-66
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    • 2008
  • This study investigated the rheological and sensory characteristics of pickle with frozen pine mushroom. P3(Developed pickle seasoning) was the best by preference among three kinds of pine mushroom pickle seasoning. For flavor and functionality, pine mushroom pickle was processed by using three kinds of method(P3-1: P3+cinnamon 10 g, P3-2: P3+licorice 10 g and P3-3: P3+licorice 5 g+cinnamon 5 g). As a result, the product from P3-3(P3+licorice 5 g+cinnamon 5 g) was the best preferred pine mushroom pickle. The pH value of P3-3 was 2.15, 42.9 degrees Brix, and its color value was L(54.65), a(-1.61), b(17.87). Its texture level was higher than that of other products, but it would be lowered on storage. Until the 28th day of storage, microorganisms in pine mushroom pickle seasoning were detected less than 30 CFU/mL.

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Case of Neck and Shoulder Posture Correction Treatment Using Yin-yang Balancing Therapy of Temporomandibular Joint (TMJ) (턱관절음양균형요법을 이용한 목과 어깨 자세교정 치험례)

  • Choi, Geun Wook;Lee, Young Jun
    • Journal of TMJ Balancing Medicine
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    • v.11 no.1
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    • pp.37-40
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    • 2021
  • Objectives: The purpose of this study is to report the effect of Korean medical treatment using Yin-yang Balancing Therapy of TMJ (YBT) on correcting posture. Methods: During the admission period, the patient was treated by Korean medical treatment (YBT, acupuncture, herb medicine, etc) every each day. The standard intraoral balancing appliance was used in patient while sleeping and exercising. Results: After treatment for 35th, the angle changed from 23 degrees to 0 degree. The posture of the neck and shoulder became straight. The distorted facial midline was aligned straight. Conclusions: These results showed that YBT have an effect on correcting posture.

Time to Recover Consciousness in Patients with Diffuse Axonal Injury : Assessment with Reference to Magnetic Resonance Grading

  • Park, Sung-Jun;Hur, Jin-Woo;Kwon, Ki-Young;Rhee, Jong-Joo;Lee, Jong-Won;Lee, Hyun-Koo
    • Journal of Korean Neurosurgical Society
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    • v.46 no.3
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    • pp.205-209
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    • 2009
  • Objective : This study was conducted to investigate the correlation between the degrees of injury on brain magnetic resonance imaging (MRI) and the time interval to recovery of consciousness in patients with diffuse axonal injury. Methods : From January 2004 to December 2008, 25 patients with diffuse axonal injury were treated at our hospital. We retrospectively investigated the patients' medical records and radiological findings. We divided the patients into three groups according to the grade of MRI finding : grade I, small scattered lesions on the white matter of the cerebral hemisphere; grade II, focal lesions on the corpus callosum; and grade III, additional focal lesions on the brain stem. Result : Seven patients belonged to the grade I group; 10 to the grade II group; and 8 to the grade III group. The mean Glasgow Coma Scale (GCS) score of all patients at the time of admission was 7.28. Recovery of consciousness was observed in 23 of the 25 patients; the remaining two patients never regained consciousness. The time interval to recovery of consciousness (awake status) ranged from 1 day to 125 days (mean 22.1 days) : grade I group patients, within approximately 1 week (mean 3.7 days); grade II group patients, within approximately 2 weeks (mean 12.5 days); and grade III group patients, within approximately 2 months (mean 59.5 days). Conclusion : Our study results suggest a correlation between the mean time interval to recovery of consciousness in patients with diffuse axonal injuries and the degrees of brain injuries seen on MRI. Patients with grade I and II diffuse axonal injuries recovered consciousness within 2 weeks, while patients with grade III injuries required approximately 2 months.

Early Unrestricted Weight-Bearing in a Stirrup Brace Following the Broström Procedure with Suture Tape for Chronic Lateral Ankle Instability (족관절 외측의 만성 불안정성에 Broström 술식과 Suture Tape을 이용한 보강술 후 조기에 시행한 등자보호대 착용 및 체중부하 보행)

  • Jaeyoung, Lee;Geon-Ho, Kwon;Jin-Wha, Chung
    • Journal of Korean Foot and Ankle Society
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    • v.26 no.4
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    • pp.171-176
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    • 2022
  • Purpose: This study reports on a series of patients with chronic lateral ankle instability that underwent the Brostrom procedure with suture tape augmentation and allowed early unrestricted weight-bearing in a simple stirrup brace. Materials and Methods: This retrospective study was conducted on 36 patients (22 males and 14 females of mean age 34 years [range 23~48 years]) with chronic lateral ankle instability treated using the Brostrom procedure using suture tape augmentation and inferior extensor retinaculum reinforcement with a fiber-wire connected to a SwiveLock screw inserted into the talus. When possible, patients started unrestricted weight-bearing in a stirrup brace from the third postoperative day. Demographics and functional outcomes, including American Orthopaedic Foot and Ankle Society (AOFAS) ankle-hindfoot, visual analogue scale (VAS), and satisfaction scores, were recorded. In addition, varus stress radiographs obtained before and 24 months after surgery were compared. Patients were followed for a mean 29 months (range 25~40 months). Results: Mean AOFAS ankle-hindfoot scores increased from 51 points preoperatively to 92 points at final follow-up, and mean VAS decreased from 6.8 to 1.2 points. Mean patient satisfaction scores were 8.7 at 12 months and 9.6 at 24 months. Stress radiographs demonstrated that talar tilt decreased from a mean 18 degrees preoperatively to 7 degrees at 24 months. Conclusion: Early unrestricted weight-bearing in a stirrup brace following the Brostrom procedure with suture tape augmentation is a successful protocol for treating chronic lateral ankle instability.

Maximizing the Probability of Detecting Interstellar Objects by using Space Weather Data (우주기상 데이터를 활용한 성간물체 관측 가능성의 제고)

  • Kwon, Ryun Young;Kim, Minsun;Hoang, Thiem
    • The Bulletin of The Korean Astronomical Society
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    • v.46 no.2
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    • pp.62.1-62.1
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    • 2021
  • Interstellar objects originate from other stellar systems. Thus, they contain information about the stellar systems that cannot be directly explored; the information includes the formation and evolution of the stellar systems and the possibility of life. The examples observed so far are 1l/Oumuamua in 2017 and 2l/Borisov in 2019. In this talk, we present the possibility of detecting interstellar objects using the Heliospheric Imagers designed for space weather research and forecasting by observing solar wind in interplanetary space between the Sun and Earth. Because interstellar objects are unpredictable events, the detection requires observations with wide coverage in spatial and long duration in temporal. The near-real time data availability is essential for follow-up observations to study their detailed properties and future rendezvous missions. Heliospheric Imagers provide day-side observations, inaccessible by traditional astronomical observations. This will dramatically increase the temporal and spatial coverage of observations and also the probability of detecting interstellar objects visiting our solar system, together with traditional astronomical observations. We demonstrate that this is the case. We have used data taken from Solar TErrestrial RElation Observatory (STEREO)/Sun Earth Connection Coronal and Heliospheric Investigation (SECCHI) HI-1. HI-1 is off-pointed from the Sun direction by 14 degrees with 20 degrees of the field of view. Using images observed from 2007 to 2019, we have found a total of 223 small objects other than stars, galaxies, or planets, indicative of the potential capability to detect interstellar objects. The same method can be applied to the currently operating missions such as the Parker Solar Probe and Solar Orbiter and also future L5 and L4 missions. Since the data can be analyzed in near-real time due to the space weather purposes, more detailed properties can be analyzed by follow-up observations in ground and space, and also future rendezvous missions. We discuss future possible rendezvous missions at the end of this talk.

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Effects of Methanol Extract of Radix Achyranthis Bidentatae on Cadmium Inhalation Toxicity in Rat (우슬 메탄올 추출물이 흰쥐의 카드뮴 흡입독성완화에 미치는 영향)

  • Kang Hong Gu;Hong Ji Woo;Han Hyun Jung;Hwang Yoo Yeon;Jeong Jae Yeal;Lee Ki Nam
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.18 no.6
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    • pp.1784-1794
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    • 2004
  • To study the effects between Cd inhalation toxicity and methanol extract of Radix Achyranthis Bidentatae, 4 rat groups were exposed to Cd aerosol by whole-body inhalation exposure for 6 hours/day, 5 days/week, and 4 weeks. Cd concentration in air was 0.98㎎/㎥ and mass median diameter(MMD) was 1.78㎛. 3 different dose intraperitoneal injections of methanol extract of Radix Achyranthis Bidentatae to 3 inhalation exposure groups applied for 4 weeks and the results were as follows: The highest body weight gain for 4 weeks and food intake per day were from inhalation exposure group Ⅲ(p<0.05). The highest lung weight was from inhalation exposure group Ⅲ and the highest liver and kidney weight were from inhalation exposure group Ⅱ(p<0.05). The lowest Cd content in lung was 22.77㎍/g from inhalation exposure group Ⅲ(p<0.05). The highest Cd concentration in blood was 11.71㎍/㎗ from inhalation exposure group Ⅰ(p<0.05). Cd concentrations of 14.87㎍/g in liver and 17.91㎍/g in kidney were the highest from inhalation exposure group Ⅰ(p<0.05). The lowest Cd concentration in liver and kidney were 5.71㎍/g and 3.17㎍/g from the control(p<0.05). For weekly Cd concentration in urine, the highest value was 0.48㎍/㎖ from inhalation exposure group Ⅲ of the 3rd week and inhalation exposure group Ⅰ, Ⅱ of the 4th week. For weekly Cd concentration in feces, the highest value was 0.32㎍/g from inhalation exposure group Ⅰ, Ⅱ, Ⅲ. The highest metallothionein concentration in lung was 89.02㎍/g from inhalation exposure group Ⅲ(p<0.05). The highest metallothionein concentrations in liver and kidney were 265.47㎍/g and 214.21㎍/g from inhalation exposure group Ⅲ, respectively(p<0.05). The highest Hct, Hb, and WBC values were from inhalation exposure group Ⅱ and the highest RBC value was from inhalation exposure group Ⅲ(p<0.05). Mostly damaged part in liver tissue was hepatic lobule and the degrees of damage were lessened by the intraperitoneal injection of methanol extract of Radix Achyranthis Bidentatae. Proximal, distal convoluted tubules and glomerulus in kidney tissue were mostly damaged part. Degeneration and swelling were partially observed but the degrees of kidney tissue damage were lessened more or less by the intraperitoneal injection of methanol extract of Radix Achyranthis Bidentatae.

The Vegetational and Environmental History of the Pre-Holocene Period in the Korean Peninsula (한반도 식생 및 환경변천사(홀로세 이전 시대를 중심으로))

  • Kong, Woo-Seok
    • The Korean Journal of Quaternary Research
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    • v.6 no.1
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    • pp.1-11
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    • 1992
  • The reconstruction of the vegetational and environmental history of the Korean peninsula by the use of various fossil floral data from the Carboniferous period to the Pre-Holocene is reviewed. Though the oldest plant fossil in Korea (Neuropteris) dates back to the Carboniferous period, the first appearance of many of the present-day floristic genera indeed dates back to the Oligocene (c. 40 to 20 million years B.P.), and includes many thermophilous genera. The presence of thermophilous genera in the Oligocene at up to four degrees north of their present distributional limits implies that the climate of the Oligocene was warmer than that of today. The occurrence of similar thermophilous floristic element at up to six degrees north of their present range during the Middle Miocene suggests a maximum northward expansion of warmth-loving evergreen broadleaved vegetation for, recent Korean vegetation history. The continued occurrence of numerous present-day genera since the Oligocene period indicates a long-term stability of Korean vegetation, along with minor fluctuations within it. The admixture of evergreen coniferous plants and deciduous breadleaved plants, however, indicates a probable temperate climate for much of the Middle Pleistocene. There are couple of evidences which are indicative of an early-stage anthropogenic disturbance of natural vegetation during the Middle Pleistocene of Korea. The presence of cold-episodes during the Upper Pleistocene caused a general expansion of deciduous plants and cryophilous evergreen coniferous, plants. It is likely that the maximum southward expansion of cryophilous arctic-alpine and alpine floras in Korea occured during the penultimate glacial period. The disappearance of some cryophilous genera from 10,000 years B.P. marks the continued climatic amelioration since then, along with minor climatic fluctuations during the Holocene period.

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Solar Energy Storage Effectiveness on Double Layered Single Span Plastic Greenhouse (2중 단동비닐하우스의 태양열 축열이용 효과)

  • Lee, Sung-Hyoun;Ryou, Young-Sun;Moon, Jong-Pil;Yun, Nam-Kyu;Kwon, Jin-Kyung;Lee, Su-Jang;Kim, Kyeong-Won
    • Journal of Biosystems Engineering
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    • v.36 no.3
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    • pp.217-222
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    • 2011
  • This study was carried out in order to reduce the amount of underground water which is used in the double layered single span plastic greenhouse for retaining heat. For this research, two plastic green houses of the double layered single span plastic greenhouse were installed. There was equipped of internal small tunnel for keeping warm air in the interior of the house. Then the internal small tunnel for keeping warm air was fitted with PVC duct of 50 cm in diameter filled with subsurface water. The surplus solar energy in the greenhouse was stored in the water in the PVC duct. Four FCUs (Fan Coil Unit), which has the capacity of 8,000 kcal per hour, were installed in the middle of the house, and a circulation motor in heat storage water tank was operated from 10:30 a.m. to 16:00 p.m. in order to circulate water between the water tank and the FCUs. Consequently about 5 degrees celsius could be maintained in the interior of the internal small tunnel for keeping warm air with the external temperature of lower than minus 5 degrees celsius. It appeared that the alteration of an internal temperature of the house was flexible depending on the sunlight during daytime. To prevent the water freezing, mixing antifreezing liquid in the water or operating FCU continuously was needed. Also, in order to use the surplus solar thermal energy on plastic green house of water curtain system efficiently, storing the surplus heat during daytime simultaneously finding a method of using water curtain systematic underground water happened to be important. As a result of this research, when the house's interior temperature is below zero the operation of FCU appeared to be impossible. Considering the amount of water used in the house with water-curtain-heating system is 150~200 ton per day, using the system mentioned in this research showed that reducing the underground water more than 80% in order to maintain the internal temperature as the level of 5 degree celsius at the extreme temperature of minus 5 degrees celsius.

A Case of Multiple System Atrophy with Antecollis and Gait Disturbance Treated with Korean Medicine (경전굴 및 보행장애를 주소로 하는 다계통 위축증 환자의 한의 치료 증례 1례)

  • Kim, Seo-young;Choi, Jeong-woo;Jeong, Hye-seon;Lee, Sang-hwa;Yang, Seung-bo;Cho, Seung-yeon;Park, Jung-mi;Ko, Chang-nam;Park, Seong-uk
    • The Journal of Internal Korean Medicine
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    • v.40 no.5
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    • pp.851-864
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    • 2019
  • Multiple system atrophy is a neurodegenerative disease that causes diverse bodily dysfunctions (cerebellar, pyramidal, automatic, and urological, in any combination), as well as Parkinsonism. Patients with multiple system atrophy commonly display antecollis, a condition where the patient's head tilts forward more than 45 degrees. Despite its common occurrence in these patients, no current standardized therapies are effective for treating antecollis. In this study, Korean medicinal treatments, including Chuna manual therapy, pharmaco-acupuncture, bee venom acupuncture, acupuncture, herbal medicine, and moxibustion therapy, were administered to the patient over a 27-day period. After the treatment, assessments of the head position on the EPIS-PD scale (Part I) and at a standing position from the side (Part II) both revealed improvements. As the head flexion angle decreased, the patient's head posture improved, as determined by a decrease in angle from 80 degrees to 30 degrees in the upright, standing position. As a result, patients who previously were unable to walk without the support of walking frames could now roam freely and independently, with significant increases in both walking speed and distance. In essence, this study suggests that Korean medicine is an effective treatment for patients with multiple system atrophy who suffer from antecollis and gait disorders.