• Asian-Australasian Journal of Animal Sciences
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• v.32 no.9
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• pp.1458-1468
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• 2019

Objective: As one of the most important metabolic organs, the liver plays vital roles in modulating the lipid metabolism. This study was to compare miRNA expression profiles of the Large White liver between two different developmental periods and to identify candidate miRNAs for lipid metabolism. Methods: Eight liver samples were collected from White Large of 70-day fetus (P70) and of 70-day piglets (D70) (with 4 biological repeats at each development period) to construct sRNA libraries. Then the eight prepared sRNA libraries were sequenced using Illumina next-generation sequencing technology on HiSeq 2500 platform. Results: As a result, we obtained 346 known and 187 novel miRNAs. Compared with the D70, 55 down- and 61 up-regulated miRNAs were shown to be significantly differentially expressed (DE). Gene ontology and Kyoto encyclopedia of genes and genomes enrichment analysis indicated that these DE miRNAs were mainly involved in growth, development and diverse metabolic processes. They were predicted to regulate lipid metabolism through adipocytokine signaling pathway, mitogen-activated protein kinase, AMP-activated protein kinase, cyclic adenosine monophosphate, phosphatidylinositol 3 kinase/protein kinase B, and Notch signaling pathway. The four most abundantly expressed miRNAs were miR-122, miR-26a and miR-30a-5p (miR-122 only in P70), which play important roles in lipid metabolism. Integration analysis (details of mRNAs sequencing data were shown in another unpublished paper) revealed that many target genes of the DE miRNAs (miR-181b, miR-145-5p, miR-199a-5p, and miR-98) might be critical regulators in lipid metabolic process, including acyl-CoA synthetase long chain family member 4, ATP-binding casette A4, and stearyl-CoA desaturase. Thus, these miRNAs were the promising candidates for lipid metabolism. Conclusion: Our study provides the main differences in the Large White at miRNA level between two different developmental stages. It supplies a valuable database for the further function and mechanism elucidation of miRNAs in porcine liver development and lipid metabolism.

• Journal of Wetlands Research
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• v.21 no.1
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• pp.27-33
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• 2019

The future water management needs decentralization of facilities, diversity of technology and integration of management to overcome the waste of financial resources and increase in scale of facilities that occurred from centralized water management. In addition, citizen's environmental awareness and participation is important because all infrastructure installed in the watershed where citizens live should have the function of water management. Therefore, the research was performed by investigating the citizen's recognition about urban environment와 LID application to analyze citizen's perceptions and analyze the feasibility and possibility of LID application. The LID awareness of citizens was about 59%, but only about 46% of citizens agreed on the extension of application. However, after contacting LID photographs and information, 90% of respondents agreed on the application of LID, and 94% of respondents were able to distinguish between grey infrastructure and LID infrastructure. Citizens appeared to have a tendency to recognize green spaces as multi-functional LID infrastructure or green infrastructure. If citizens recognize multi-functional LIDs only as landscapjng area, it will be very difficult to extend the LID on the city areas. Therefore, for the extended application of the LID facilities, it is necessary to use public relations strategy to utilize the results and visual data on the actual effect verification. In addition, as every social infrastructure is formed in watershed where citizens live, it is necessary to plan and manage the infrastructure through governance with citizen participation.

• Journal of the Korean BIBLIA Society for library and Information Science
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• v.29 no.4
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• pp.91-111
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• 2018

This study was carried out on specialized library librarians to investigate the status and overall satisfaction of specialized services and to compare the degree of importance and satisfaction of specialized subject data, specialized service places, specialization programs, specialized subject area facilities and environment based on ISA technique in order to derive problems and improvement measures for the operation of specialized libraries. As results, first, it was found that a specialized library subject should be selected based on the characteristics, history, and resources of the library location as well as based on the demand survey of the local residents and users. Second, based on the appropriate program type of specialized subject and the results from users' demand surveys, specialized libraries should develop different types of experience-type, lecture-type, view-type and the likes. Third, specialized library space types can be divided into integrated type, independent-in-integration type, and independent type. Even though it is most ideal to provide independently specialized space, the space must be constructed considering the circumstances and subject of specialization of each library. Fourth, specialized libraries should have at least one dedicated specialist in the corresponding subject. Dedicated specialists should provide lending and reference services related to the specialization such as tidying, browsing, reading and operating specialized programs. And a dedicated specialist must be an expert in the specialized subject and also a librarian who is responsible of the general library operation.

• Journal of Digital Convergence
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• v.17 no.8
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• pp.229-235
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• 2019

As the demand for broadband multimedia including the Internet explosively increases, the advancement of the subscriber network is becoming the biggest issue in the telecommunication industry due to the surge of data traffic caused by the emergence of new services such as smart phone, IPTV, VoIP, VOD and cloud services. In this paper, we have developed WDM(Wavelength Division Multiplexing)-PON(passive optical network) based on the 1-Gigabit Reach Externder (RE) technique to reduce optical core. Particularly, in order to strengthen the market competitiveness, we considered low cost, miniaturization, integration technique, and low power of optical parts. In addition, we have developed a batch system by integrating all techniques for reliability, remote management through the development of transmission distance extension and development of capacity increase of optical line by using RE technology in existing PON network. Based on system interworking with existing commercial 1G PON devices, it can be worthy of achievement of wide nationalization and optical core reduction by using this developed system. Based on these results, we are studying development of 10G PON technology.

• The Journal of Society for e-Business Studies
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• v.24 no.3
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• pp.111-128
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• 2019

In the current procurement system in Korean military, the army, navy and air force have their own distributors, military branches and warehouses. However, especially, it has been hard to have the economy of scale because most of suppliers have shipped their order from the suppliers to each of Korean military directly. Koran military considers the transportation cost as one of the management cost factors among various kinds of cost. Furthermore they have contracted with the suppliers in annual and collectively on the transportation. Hence they have been in trouble with getting efficiency of Defense budget execution because it is hard to make a decision of Defense budget with real transportation cost. Moreover Korean army, navy and air force have their own supply chain separately, so they can not cooperate flexible and quickly when they need. Therefore, in this research, we provide a benchmarking of DTCI (Defense Transportation Coordination Initiative) which has been proved that it has improved the procurement system in US implementing the integrated transportation system with 3PL and military. In addition we propose advanced integrated shipping model using Hub & Spoke system for Korean military. In order to prove its effect, we simulate our model based on the real data of the suppliers' delivery to compare with the current system when it comes to how much we can save the cost. Our research can provide evidence that the integrated procurement system in Korean military will improve Korean military procurement system.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.5
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• pp.538-549
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• 2019

This study suggests a new platform in which VI can communicate with their guardians who serve as a system administrator optimizing personal characteristics. In terms of interaction between platform components, this study can contribute to enhancing stability of walking by giving substantial information to VI through server processing and setups of guardians with real-time interaction to VI through server processing and setups of guardians with real-time interaction. Therefore, developing smart phone applications can facilitate both portability and cost effectiveness, by the users' downloading the application and registration. In terms of guardians' cost, this system is cost-effective because they can access to the administration system through personal computers or smart phones, not through specialized system devices. This system is web-based, which automatically communicates with the surroundings of, such as provides the guardians with the necessary information or approaches to the danger through IoT devices, which results in enhancing safety. Moreover, it is possible for guardians to utilize the personalized platform since the system not only senses personal characteristics but also sends a number of information to VI. a new platform makes it possible for guardians to provide electronic support and interaction with the application with the application users, which contributes to systematic and safe walk for VI.

• Journal of Digital Convergence
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• v.17 no.1
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• pp.209-217
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• 2019

In this paper, the purpose of this paper is to lay the foundation for the search system by using and building an online search engine suitable for the search domain and enabling search, conversion, integration and sharing of information. It is to use the ontology to infer hierarchical relationships, deduce objects based on that layer, and extract attributes to search areas that are relevant to the data that the user wants. In order to search for information in this way, the information search system was implemented by entering key words related to 'qualifications'. The implemented system arranged the meaning and relationship of each attribute online so that the general public can search information quickly, easily, and accurately. In addition, the implementation results were compared with two different search engines. Comparable search engines are Naver and Daum, the two major search engines. The search engine of this study, which was built using an ontology suitable for the search domain to perform searches using the semantic web, was evaluated to have excellent results. However, it is thought that a more formalized online location is necessary to increase the accuracy and reliability of search engines and to include more comprehensive categories of search terms.

• The Journal of the Korea Contents Association
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• v.21 no.10
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• pp.738-752
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• 2021

This study was to applied QIMS(Qualitative Interpretive Meta-Synthesis) which was newly introduced in the field of social science recently to explore the client violence experience and coping in the social workers in a new way and in depth. The integrated analysis of the results of qualitative individual studies published in Korea so far has resulted in abundant results with accumulated knowledge and synergistic understanding paths of existing research results, and the limitations of qualitative research have been overcome. Eight published papers from 2013 to 2020 were included in the final analysis, and a total of 85 social workers analyzed the statements. The newly important themes created through the process of reducing the scope of data and the repetition of theme extraction and integration were divided into four categories: (1) violence and pain that can not be removed, (2) duality experienced as a result of occupation, (3) continuous attempts to change, (4) manifestation of sense of duty and job meaning. Based on the results of the integrated themes derived from this study, this study aims to present practical and policy alternatives to the prevention and coping of client violence experienced by social workers in various social welfare practice fields.

• Journal of the Korea Convergence Society
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• v.12 no.3
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• pp.297-304
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• 2021

This study aims not only to access the visual thought-oriented approach that has been implemented in established art therapy and education but also to integrate language education and therapeutic approach to support the development of school-age children. Thus, text mining technique was applied to search for areas where different areas of language and art can be integrated. This research was conducted in accordance with the procedure of basic research, preliminary DB construction, text screening, DB pre-processing and confirmation, stop-words removing, text mining analysis and the deduction about the convergent areas. These results demonstrated that this study draws convergence areas related to regional, communication, and learning functions, areas related to problem solving and sensory organs, areas related to art and intelligence, areas related to information and communication, areas related to home and disability, topics, conceptualization, peer-related areas, integration, reorganization, attitudes. In conclusion, this study is meaningful in that it established a framework for designing an activity-centered convergence program of art and language in the future and attempted a holistic approach to support child development.

• 한국노년학
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• v.36 no.3
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• pp.611-632
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• 2016

Solutions for elderly health issues need to be found that take into account not only a medical perspective, but also interactions with social conditions such as socioeconomic status. With this in mind, this study aims to understand how socioeconomic status leads to health inequalities for the elderly. Specifically, this study investigates the mediating effects of socioeconomic status(income and education levels), health activities as an intermediary of the three dimensions of physical health(medical health, functional health, subjective health), accessibility of medical facilities, social participation, and social network. To test the research model, a secondary data analysis was conducted on the 2014 National Survey of Senior Citizens. The participants of the study were 10,451 elderly men and women aged 65 and above. To test the mediated model, hierarchical multiple regression analysis was conducted following the procedures suggested by Baron and Kenny(1986). In addition, a Sobel test was conducted to test the mediated model's significance. According to the analysis, the effects of income and educational levels on the health of the elderly were not the same. Additionally, different results were found depending on health dimensions. However, the overall direction of the results showed that the socioeconomic status of the elderly creates health disparities, and health behaviors, accessibility of medical facilities, social participation, and social network had significant mediation effects between socioeconomic status and physical health. Study findings especially worth noting are as follows: education was shown to have a stronger effect on health than income; effects of social integration factors such as social participation were highlighted; and significant mediating effects on the accessibility of medical facilities remained even after taking residential area into account. Results of this study shed light on health inequality mechanisms due to socioeconomic conditions and the need to find alternatives to alleviate these problems.