• Journal of KIISE:Databases
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• v.29 no.6
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• pp.500-500
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• 2002

Most of previous replication schemes assume lazy schemes, which asynchronously propagate replica updates to other nodes after the updating transaction commits. While lazy schemes are novel in the sense that they can resolve high deadlock frequencies of eager schemes, they suffer from the fact that users should be responsible for the data consistency. Recently replication schemes based on the messaging order of group communication have been studied. They can reduce the deadlock frequencies using the messaging order, but they have another problem of increasing execution overhead of aborted transactions at high degree of concurrency. This is because the sender node validates global serializability after multicasting replica update messages to other nodes. In this paper, we propose an efficient eager replication scheme for reducing the number of messaging and overhead of aborted transactions significantly. The proposed scheme validates any conflicts before multicasting and does not multicast when there is any conflict; hence, it can exploit performance improvement by alleviating the message traffic for replica update or by reducing the number of disk accesses and locking delay due to aborted transactions.

• Proceedings of the Korean Society for Technology of Plasticity Conference
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• 2005.09a
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• pp.35-40
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• 2005

The demand for small and high-capacity optical data storage devices has rapidly increased. The areal density of optical disk is increased using higher numerical aperture objective lens and shorter wavelength source. A wafer-scale stacked micro objective lens with a numerical aperture of 0.85 and a focal length of 0.467mm for the 405nm blue- violet laser was designed and fabricated. A diffractive optical element (DOE) was used to compensate the spherical aberration of the objective lens. Among the various fabrication methods for micro DOE, the UV-replication process is more suitable for mass-production. In this study, an 8-stepped DOE pattern as a master was fabricated by photolithography and reactive ion etching process. A flexible mold was fabricated for improving the releasing properties and shape accuracy in UV-molding process. In the replication process, the effects of exposing time and applied pressure on the replication quality were analyzed. Finally, the shapes of master, mold and molded pattern were measured by optical scanning profiler. The deviation between the master and the molded DOE was less than 0.1um. The efficiency of the molded DOE was measured by DOE efficiency measurement system which consists of laser source, sample holder, aperture and optical power meter, and the measured value was $84.5\%$.

• Biomedical Science Letters
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• v.23 no.4
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• pp.372-379
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• 2017

This study was investigated to test whether paternal DNA that was destined for degradation was properly licensed by testing for the presence of mini-chromosome maintenance protein (MCM) 7 and origin recognition complex (ORC) 2 in the paternal pronuclei. ORC2 is one of the first licensing protein to come on and MCM7 is one of the last licensing protein to come on. Zygotes were prepared by injection of control and treated sperm injection (ICSI). To control for DNA breakage, epididymal spermatozoa were treated with DNase I to fragment the DNA, then injected into oocytes. The presence of MCM7 and ORC2 in the pronuclei of mouse zygotes was tested by immunohistochemistry, just before the onset of DNA synthesis, at 5 h after fertilization, and after DNA synthesis began, at 9 h post fertilization. We found that in all cases, both MCM7 and ORC2 were present in both pronuclei at 5 h after sperm injection, just before DNA synthesis began. This indicates that no matter how extensive the DNA damage, recruitment of licensing proteins to the origins of replication was not inhibited. Sperm DNA fragmentation does not prevent licensing of DNA replication origins. Furthermore, the embryo recognizes DNA that is damaged by nucleases. Our data indicate that the one-cell embryo does harbor a mechanism to prevent the replication of severely damaged DNA from spermatozoa, even though the embryos do not undergo classical apoptosis.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.10
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• pp.4199-4202
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• 2015

Background: Hepatitis B virus infection is one of the major world health problems. Epigallocatechin-3 gallate is the major component of the polyphenolic fraction of green tea and it has an anti-viral, anti-mutagenic, anti-tumorigenic, anti-angiogenic, anti-proliferative, and/or pro-apoptotic effects on mammalian cells. In this study, our aim was to investigate the inhibition of HBV replication by epigallocatechin-3 gallate in the Hep3B2.1-7 hepatocellular carcinoma cell line. Materials and Methods: HBV-replicating Hep3B2.1-7 cells were used to investigate the preventive effects of epigallocatechin-3 gallate on HBV DNA replication. The expression levels of HBsAg and HBeAg were determined using ELISA. Quantitative real-time-PCR was applied for the determination of the expression level of HBV DNA. Results: Cytotoxicity of epigallocathechin-3-gallate was not observed in the hepatic carcinoma cell line when the dose was lower than $100{\mu}M$. The ELISA method demonstrated that epigallocatechin-3 gallate have strong effects on HBsAg and HBeAg levels. Also it was detected by real-time PCR that epigallocatechin-3 gallate could prevent HBV DNA replication. Conclusions: The obtained data pointed out that although the exact mechanism of HBV DNA replication and related diseases remains unclear, epigallocatechin-3 gallate has a potential as an effective anti-HBV agent with low toxicity.

• Journal of KIISE:Computer Systems and Theory
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• v.31 no.9
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• pp.503-513
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• 2004

In large distributed systems, replications of data and service are needed to decrease communication cost, increase availability, and avoid single server bottleneck. Tree Quorum protocol is a representative replication protocol, which exploits a logical structure. Tree quorum protocol is one of the replication protocols allowing low read cost only in the best case, while the number of replicas exponentially increases as the level grows. In this paper, thus, we propose a new replication protocol, called symmetric tree protocol which efficiently solves the problem. The proposed symmetric tree protocol also requires much smaller read cost than previous protocols. We conduct cost and availability analysis of the protocols, and the proposed protocol displays comparable read availability to the tree protocol using much smaller number of nodes. Also, the symmetric tree protocol has much smaller response time than the logarithmic protocol.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.17 no.5
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• pp.1129-1137
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• 2013

Cloud storage system that cloud computing providers provides large amounts of data storage and processing of cloud computing is a key component. Large vendors (such as Facebook, YouTube, Google) in the mass sending of data through the network quickly and easily share photos, videos, documents, etc. from heterogeneous devices, such as tablets, smartphones, and the data that is stored in the cloud storage using was approached. At time, growth and development of the globally data, the cloud storage business model emerging is getting. Analysis new network storage cloud storage services concepts and technologies, including data manipulation, storage virtualization, data replication and duplication, security, cloud computing core.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.8 no.5
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• pp.187-195
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• 2008

In MANET, it is important to efficiently manage data objects and traffic to improve network throughput and response time. This paper proposes a connection-degree based data object search and replication scheme in mobile ad-hoc networks. In this method, information about the path data object providers is stored at the cache of a cluster header at which lots of queries arrive, so that, to reduce the load of the cluster header, replicas can be created at its neighboring nodes. The method proposes an algorithm that picks up a cluster header among mobile nodes and makes it possible to search for and utilize adaptive and up-to-date information in MANET. The method is expected to be effective since it enables access to data objects in spite of broken links among mobile nodes with an enhancement in network response time of searching and a decrease in communication costs. The efficiency of this system was verified via simulation.

• ETRI Journal
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• v.29 no.3
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• pp.281-291
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• 2007

Wearable computers consisting of various small devices such as smart phones, digital cameras, MP3 players and specialized I/O devices in personal area networks will play an important role in future ubiquitous computing. In this environment, accessing user data is quite complex due to the dynamic and heterogeneous characteristics of the underlying networks. Moreover, since the amount of user data increases rapidly, automatic data backup management is also critical. To overcome these challenges, several studies have been conducted including our previously proposed file service system, PosCFS, which could be adapted to the requirements with a virtualization technique allowing per-user global namespace for managing and accessing data stored on physical storage spaces detected in PAN. In this paper, we present a smart file service framework, PosCFS+ which is an improved and extended version of our previous work. Performance improvement is made possible by redesigning the metadata management scheme based on database and keywords rather than ontology. In addition, the automatic data replication management is newly designed based on the OSD protocol.

• Journal of the Korean Data and Information Science Society
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• v.19 no.2
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• pp.645-655
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• 2008

As wireless connectivity is integrated into many handheld devices, streaming multimedia content among mobile ad-hoc peers is becoming a popular application. In this paper, we propose a dynamic service replication algorithm for providing guaranteed continuous streaming services to all nodes in mobile ad-hoc networks (MANETs). First, a MANET is comprised of logical grid hierarchy, and a streaming service is replicated to a lower server region of the logical grid hierarchy by considering the link availability between a mobile node and the streaming server within a server region or the popularity of the streaming service. We evaluate analytically the performance of the proposed algorithm, and compared with that of existing Qin's algorithm. Evaluation results show that our algorithm can achieve better streaming performance than Qin's algorithm. Therefore, the proposed algorithm not only improves the sharing availability of replicated streaming services but also controls efficiently the number of streaming service replications.

• Journal of the Microelectronics and Packaging Society
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• v.18 no.1
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• pp.7-13
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• 2011

According to increasing of data transfer rate, printed circuit board (PCB) is required improvement of transmission speed. Optical PCB and its packaging technology can be one of the solutions that overcome the limitations of conventional electrical PCB. The data transmission capacity will be increased 10 Tbps at 2015. To this end, studies on various OPCB technologies are being conducted. For cost-effective and high- performance OPCB, studies of optical coupling by polymer replication process are conducted. In this work, optical waveguide and optical fiber array block were sequentially fabricated by polymer pattern replication method. Using this method we successfully demonstrate low loss optical fiber coupling between optical waveguide and optical fiber arrays. And researches on flip chip bonding process and using electro-optic connectors for packaging are conducted.