• Journal of Science Education
• /
• v.38 no.3
• /
• pp.641-656
• /
• 2014

This study aimed at analyzing visual materials included in school science textbooks, specifically the textbooks for first semester courses of 3rd to 6th graders. The purpose was to provide directions for future textbooks by understanding the functions of the images in both pedagogical and social perspectives as well. The study was conducted by investigating the types, roles and socio-semiotic features of the images in science textbooks. The results were as follows. Firstly, the most used types of images in 2007 curriculum textbooks were photographs and drawn pictures. Uses of other visual aids than above were extremely rare. It was also found that as the educational level rises, the use of images for decorative functions drastically declined. The majority of the images were used in providing supplementary explanations or examples. This implies that the images effectively play the role of helping science education. In addition, more use of worksheets images was found, indicating that as educational level increases, students participate more actively in research sessions or data analysis. In socio-semiotic perspective, visual images showed high accessibility to students in 'Type of visual image', 'Function of visual image', 'Distance of shot', 'Horizontal angle of shot', 'Color moduation'. It was implied that there will a close correlation between the type, role and the socio-semiotic characteristics of visual images in textbooks. For example, photograph-type visuals were mostly used as supplementary references. And when applying the socio-semiotic analysis to photograph-type visuals, they showed 'real type', 'narrative-metaphor type', and 'shadow effect' among socio-semiotic features. Such correlations implied that knowing the type of the visual image may help determining the role of the image in the textbook to some extent, and also corresponding socio-semiotic characteristics. As a result, it was possible to infer how accessible certain visual images are to students. The above results have implications for the effective use of visual images in future textbooks.

• Radiation Oncology Journal
• /
• v.18 no.2
• /
• pp.107-113
• /
• 2000

Purpose : The goal of this study 닌as to improve the accuracy of three-dimensional conformal radiotherapy (3-D CRT) by measuring the treatment setup error and physiological movement of liver based on the analysis of images which were obtained by electronic portal imaging device (EPID). Materials and Methods : For 10 patients with hepatocellular carcinoma, 4-7 portal images were obtained by using EPID during the radiotherapy from each patient daiiy. We analyzed the setup error and physiological movement of liver based on the verification data. We also determined the safety margin of the tumor in 3-D CRT through the analysis of physiological movement. Results : The setup errors were measured as 3mm with standard deviation 1.70 mm in x direction and 3.7 mm with standard deviation 1.88 mm in y direction respectively. Hence, deviation were smaller than 5mm from the center of each axis. The measured range of liver movement due to the physiological motion was 8.63 mm on the average. Considering the motion of liver and setup error, the safety margin of tumor was at least 15 mm. Conclusion : EPID is a very useful device for the determination of the optimal margin of the tumor, and thus enhance the accuracy and stability of the 3-D CRT in patients with hepatocellular carcinoma.

• 한국해양학회지
• /
• v.18 no.1
• /
• pp.55-63
• /
• 1983

The study on the periodic and correlation analysis between water temperature and air temperature has beenconducted by oceanographic data obtained from 1923 to 1979 (For 16-51 years) in 6 ststions in the Korean Waters. The periodic and correlation analyses has been examined by method of he Schuster's and the quadratic formula of least squares method, respectively. The results pbtained from the study are as follows; 1. Periodic analysis 1) The yearly difference between max. and mini. fo surface water temperature was 12.77-17.99$^{\circ}C$ (computed value : 11.67-16.64$^{\circ}C$) in offshore waters, and was 15.72-26.33$^{\circ}C$ (computed value : 15.13-25.29$^{\circ}C$) in inshore waters, and that of air temperature was 21.71-28.60$^{\circ}C$ (computed value : 10.50-27.22$^{\circ}C$). 2) The yearly mean of water temperature by station was 11.25-18.78$^{\circ}C$, and that of air temperature was 11.39-16.16$^{\circ}C$. 3) The annual compnent amplitrde of water temperature was 5.72-12.54$^{\circ}C$, and that of air temperature was 10.04-13.49$^{\circ}C$. 4) The semi-annual component amplitude of water temperature was 0.83-1.30$^{\circ}C$, and that of air temperature was 0.72-1.26$^{\circ}C$. 5) The annual component phase of water temperature was 215-228$^{\circ}C$ (max. temperature shall be in the first and in the middle ten days of August) in inshore waters and 138-244$^{\circ}C$ (max. temperature shall be in the first and in the middle ten days of August) in offshore waters, and that of air temperarture was 212-221$^{\circ}C$ (max. temperature shall be in the first and in the middle ten days of July and in the first tin days of August). 6) The semi-annual component phase of water temperature was 87-110$^{\circ}C$ in offshore waters, and 167-212$^{\circ}C$ in inshore waters, and that of air temperature was 156-189$^{\circ}C$. 2. Correlation analyses of water temperature and air temperature before one month. 1) When the water temperature is in rising time, the quadratic constant of correlation formual was the gradual inreasing type ( constant; 0.010-0.026) in offshore waters, and the gradual decreasing or proportional type (constant; -0.020-0.001) in inshore waters. 2) when the water temperature is in descending time, the quadratic constant of correlation formula was the gradual increasing type (constant: 0.012-0.021) 3) the determination coefficient was 0.964-0.992 at rising time and 0.982-0.999 at descending time of water temperature.

• Journal of Plant Biotechnology
• /
• v.43 no.3
• /
• pp.359-366
• /
• 2016

Tradescantia is a perennial plant in the family of Commelinaceae. It is known to be sensitive to radiation. In this study, Tradescantia BNL 4430 was irradiated with gamma radiation at doses of 50 to 1,000 mGy in a phytotron equipped with a $^{60}Co$ radiation source at Korea Atomic Energy Research Institute, Korea. At 13 days after irradiation, we extracted RNA from irradiated floral tissues for RNA-seq. Transcriptome assembly produced a total of 77, 326 unique transcripts. In plantlets exposed to 50, 250, 500, and 1000 mGy, the numbers of up-regulated genes with more than 2-fold of expression compared that in the control were 116, 222, 246, and 308, respectively. Most of the up-regulated genes induced by 50 mGy were heat shock proteins (HSPs) such as HSP 70, indicating that protein misfolding, aggregation, and translocation might have occurred during radiation stress. Similarly, highly up-regulated transcripts of the IQ-domain 6 were induced by 250 mGy, KAR-UP oxidoreductase 1 was induced by 500 mGy, and zinc transporter 1 precursor was induced by 1000 mGy. Reverse transcriptase (RT) PCR and quantitative real time PCR (qRT-PCR) further validated the increased mRNA expression levels of selected genes, consistent with DEG analysis results. However, 2.3 to 97- fold higher expression activities were induced by different doses of radiation based on qRT-PCR results. Results on the transcriptome of Tradescantia in response to radiation might provide unique identifiers to develop in situ monitoring kit for measuring radiation exposure around radiation facilities.

• Research in Plant Disease
• /
• v.8 no.2
• /
• pp.84-91
• /
• 2002

Disease forecasting in Korea was first studied in the Department of Fundamental Research, in the Central Agricultural Technology Institute in Suwon in 1947, where the dispersal of air-borne conidia of blast and brown spot pathogens in rice was examined. Disease forecasting system in Korea is operated based on information obtained from 200 main forecasting plots scattered around country (rice 150, economic crops 50) and 1,403 supplementary observational plots (rice 1,050, others 353) maintained by Korean government. Total number of target crops and diseases in both forecasting plots amount to 30 crops and 104 diseases. Disease development in the forecasting plots is examined by two extension agents specialized in disease forecasting, working in the national Agricul-tural Technology Service Center(ATSC) founded in each city and prefecture. The data obtained by the extension agents are transferred to a central organization, Rural Development Administration (RDA) through an internet-web system for analysis in a nation-wide forecasting program, and forwarded far the Central Forecasting Council consisted of 12 members from administration, university, research institution, meteorology station, and mass media to discuss present situation of disease development and subsequent progress. The council issues a forecasting information message, as a result of analysis, that is announced in public via mass media to 245 agencies including ATSC, who informs to local administration, the related agencies and farmers for implementation of disease control activity. However, in future successful performance of plant disease forecasting system is thought to be securing of excellent extension agents specialized in disease forecasting, elevation of their forecasting ability through continuous trainings, and furnishing of prominent forecasting equipments. Researches in plant disease forecasting in Korea have been concentrated on rice blast, where much information is available, but are substan-tially limited in other diseases. Most of the forecasting researches failed to achieve the continuity of researches on specialized topic, ignoring steady improvement towards practical use. Since disease forecasting loses its value without practicality, more efforts are needed to improve the practicality of the forecasting method in both spatial and temporal aspects. Since significance of disease forecasting is directly related to economic profit, further fore-casting researches should be planned and propelled in relation to fungicide spray scheduling or decision-making of control activities.

• Research in Plant Disease
• /
• v.17 no.1
• /
• pp.66-74
• /
• 2011

In 2005, a survey was conducted to identify virus diseases on victory onion, Allium victorialis var. platyphyllum grown in Ulleung island located in the East Sea. A total of 61 samples were collected from victory onion in the neighborhood of Seonginbong. The identification of viruses from the samples were carried out by electron microscopy and RT-PCR using primers species specific to GCLV, LYSV, SLV, OYDV and genus specific to Allexivirus, respectively. From sixty-one samples, filamentous rod particles (600-900 nm) were detected from four victory onion samples in EM, three samples containing SLV and one sample containing both SLV and Allexivirus in RT-PCR analysis, respectively. Victory onions naturally infected by the viruses were asymptomatic apparently. The viruses detected by RT-PCR were further characterized by the nucleotide sequence analysis of the coat protein region. Three isolates of SLV showed approximately 99% identities in the nucleotide and amino acid sequences, suggesting that they were likely to be the same strain. On the other hand, they showed approximately 75.7~83.7% identities in the nucleotide and 89.2~97.0% in amino acid sequences compared with the previously reported SLV isolates in Allium. The CP gene of the Allexivirus showed approximately 99.2% nucleotide identities and 98.8% amino acid identities with Garlic virus A. However, there was relatively low homology ranging from 60.6% to 81.5% compared with other Allexiviruses (GarV-C, GarV-E, GarV-X, GMbMV, and Shal-X). These data suggested that two viruses, SLV and GarV-A identified from victory onion, are named SLV-Ulleungdo and GarV-A-Ulleungdo, respectively. This is the first report of viruses infecting victory onion.

• Journal of The Korean Society of Grassland and Forage Science
• /
• v.35 no.4
• /
• pp.309-315
• /
• 2015

In order to identify the causes of various problems related to forage crop growth, such as winter survival, coldness, rainfall, drought etc., and to provide basic data for the stable production and supply of forage year round, we performed a growth survey after the wintering of winter forage crops grown from mid-Sep. 2014 to late-Feb. 2015. The growth of winter forage crops after wintering in the country was generally bad. As shown in the regional distribution in the country, regions with 80% or higher winter survival rates comprised 66%, regions with 79 to 50% winter survival comprised 24.9% and regions with less than 50% winter survival comprised 9.1%. In conclusion, the average winter survival rate was 79% in the country. Winter survival rate and coverage rate after the wintering of winter forage crops under installed drain channels in paddy fields were good at 83% and 80%, respectively. However, the rates without installed drain channels were bad at 67% and 66%, respectively. It was predicted that the crop production of winter forage crops was reduced by 10-15% in Gangwon, Chungbuk, Chungnam, Gyeongnam and Jeonnam regions, reduced by 30% in Gyeonggi, Gyeongbuk and Jeonbuk regions and reduced overall by approximately 19% nationwide.

• Journal of Life Science
• /
• v.29 no.12
• /
• pp.1305-1313
• /
• 2019

Licochalcone (LC), isolated from the roots of Glycyrrhiza inflata has multiple pharmacological effects including anti-inflammatory and anti-tumor activities. To date, Licochalcone C (LCC) has induced apoptosis and inhibited cell proliferation in oral and bladder cancer cells, but lung cancer has not yet been studied. In addition, no study reported LCC-induced autophagy in cancer until now. The present study was designed to investigate the effect of LCC on gefitinib-sensitive and -resistant lung cancer cells and elucidate the mechanism of its action. The 3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide assay data showed that LCC significantly inhibited cell viability in non-small cell lung cancer (NSCLC) HCC827 (gefitinib-sensitive) and HCC827GR (gefitinib-resistant) cell lines. Interestingly, Annexin V/7-aminoactinomycin D double staining and cell cycle analysis showed an apoptosis rate within about 20% at the highest concentration of LCC. LCC induced G2/M arrest by reducing the expression of the cell cycle G2/M related proteins cyclin B1 and cdc2 in NSCLC cell lines. Treatment of LCC also induced autophagy by increasing the expression of the autophagy marker protein microtubule-associated protein 1 light chain 3 (LC3) and the protein autophagy-related gene 5 involved in the autophagy process. In addition, LCC increased the production of reactive oxygen species (ROS), and the cell viability was partially restored by treatment with the ROS inhibitor N-acetyl-L-cysteine. In western blotting analysis, the expression of cdc2 was increased and LC3 was decreased by the simultaneous treatment of NAC and LCC. These results indicate that LCC may contribute to anti-tumor effects by inducing ROS-dependent G2/M arrest and autophagy in NSCLC. In conclusion, LCC treatment may be useful as a potential therapeutic agent against NSCLC.

• Korean Journal of Clinical Laboratory Science
• /
• v.39 no.2
• /
• pp.113-121
• /
• 2007

Hearing loss is a common congenital disorder that is frequently associated with mutations in the Cx26 gene (GJB2). Recently, the mutation analysis of GJB2 has been used in a newborn screening test for the detection of hearing impairment. Population-based studies should be performed before the application of genetic testing for the identification of deaf newborns. In this study, 8 positions of GJB2 mutations-including 35delG, 167delT, 235delC, V27I, V37I, M34T, E114G, and I203T-were analyzed using PCR-direct sequencing in a total of 437 healthy Korean neonates. DNAs from dried blood spots were extracted using a commercial DNA extraction kit. The PCR-amplified products (783 bps) of the GJB2 gene were detected using 2% agarose gel electrophoresis and subjected to direct sequencing. The sequences were compared with those in the GenBank database by using the BLAST program. In this study, 5 GJB2 mutations -including V27I (79G>A), V37I (109G>A), E114G (341A>G), I203T (608T>C), and 235delC- were found. Of the 437 neonate samples, 301 subjects showed GJB2 mutations (68.9%, 301/437). The V27I mutation was found in 271 subjects and was the most frequent (62.0%, 271/437). The E114G, I203T and V37I mutations were shown in 146, 17 and 14 subjects, respectively. The 235delC mutation was found in 1 subject. The E114G mutation was frequently accompanied by the V27I mutation. V27I/E114G (97.2%, 143/147) was the most common double mutation and 3 subjects had the double mutation V27I/I203T. A triple mutation, V27I/E114G/I203T, was found in 1 subject. In conclusion, PCR-direct sequencing is a convenient tool for the rapid detection of GJB2 mutations and this data might provide information for the genetic counseling of the GJB2 gene.

• Fire Science and Engineering
• /
• v.19 no.1 s.57
• /
• pp.1-19
• /
• 2005

The following matters were confirmed through the analysis of casualties due to fires in Korea, Japan, and the U.S. in this paper. 1 Korean statistics are not the most detailed of the three countries about casualties due to fires, so we need to have detailed statistics of them on casualties more. 2. Korean deaths are the lowest by 10-11 people due to fires per one million of population. Those of Japan are 15-17 and about 12 people in the U.S.; decreased about 2/3 only for a quarter of a century. 3. Korean deaths are on the decrease about 1.5 people per 100 cases due to fires,3.5 in Japan and 0.2-0.3 in the U.S. Likewise, Korean injuries are on the decrease per 100 cases due to fires From 14.9 in 1977 to 5.1 in 2001 and 5.3 in 2002. In the U.S., the figure was 1.0-1.6. but after the year 1994, it was 1.2 or so. It tends to some increase to 2.6-2.8 in Japan. Therefore, when fires are happened, the death probability is the highest in Japan and 15 times higher than that of the U.S. The injury probability is the highest in Korea and 5 times higher than that of the U.S. 4. Fire deaths rate is the highest in the U.S. about $80\%$ due to home fires (including apartments) among all deaths. Japan tends to decrease of $55\%$. Recently, in case of Korea. it is similar level to that of Japan. 5. Korean aged people of 65 years old and over exceeded by $7\%$ in 2000 and entered an aging society, so It Is time to Investigate and take effect policies to reduce the death of the aged . Japan has ahead a super-aged society that exceeds $20\%$ of the people over the age 65, and many of them die of fire. Consequently, Japan has taken effect policies to reduce deaths from 10 years or more than before. Therefore, it is a good proposal to analyze the policies of Japan deeply and study introduction of them.