• 약학회지
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• 제38권4호
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• pp.462-468
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• 1994

Hot aqueous extracts of 130 herbal medicines were screened for platelet activating factor (PAE) receptor binding antagonistic activity using rabbit platelet. The results suggested that 4 medicinal plants including Biota orientalis are potential sources of PAF antagonists.

• Archives of Pharmacal Research
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• 제8권1호
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• pp.42-44
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• 1985

Polysaccharides were isolated with alkaline extraction method from twelve pharmaceutical plants, which have been used against the various tumors in the oriental herb medicine, and examined for their antitumor activities. When the polysaccharides were administered i. p. at the dose of 10mg/kg/day for ten consecutive days to the male ICR mice, which had been implanted with $1{\times}10^{6}$ cells of sarcoma 180 twentyfour hours before the first injection of polysaccharides, those from Forsythia Corea, Curcuma, Zedoaria, Albizzia Julibrissin, Prunuts Persica, Foeniculum Vlugare and Daphne Pseudogenkwa showed inhibition ratios of 88.0%, 61.1%m 73.0%, 72.8% 55.1% and 71.7%. The significant prolongation of life span was observed only in the case of Forsythia Corea (18.1%). Other six polysaccharide fractions from Olibanum, Lonicera Japonica, Rheum Coreanum, Scirpus Maritimus, Gleditchia Officinalis and Brassica Juncea showed negligible inhibition ratios.

• 한국식물병리학회:학술대회논문집
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• 한국식물병리학회 2003년도 정기총회 및 추계학술발표회
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• pp.148.1-148
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• 2003

Natural virus infection of cultivated Daphe odora plants showing chlorosis and stunting was observed and their causal agent was investigated. An isolate of isometic virus was purified from infected leaf tissues, and it could infect systemic severe mosaic on Chenopodium quinoa and C. amaranticolor. cDNA library was generated from partially purified viral RNAs and oligo dT primer-pSPORTl system, and recombinant clones were selected and their inserts were sequenced randomly. Nucleotide sequences of the virus were analyzed by BLAST, and it was closely related to members of subgroup B in the genus Nepovirus. The sequence analysis suggest that the virus was identified as an isolate of Cycas necrotic stunt virus (CNSV) because it was 89.7 ％ and 94.7 ％ identical to known CNSV for the CP and 3' noncoding region, respecitively. RT-PCR was performed to screen disease incidence of CNSV in Daphe plants, and five out of 10 plants (50 ％) were infected by CNSV This is the first sequence information of CNSV from Daphe plants.

• 아시안잔디학회지
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• 제24권1호
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• pp.1-8
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• 2010

골프장에서 지렁이의 발생생태와 식물체 유래 물질이 지렁이의 발생에 미치는 영향을 경기도 가평베네스트골프장과 안성베네스트골프장, 부산의 동래베네스트골프장에서 알아보았다. 지렁이의 밀도를 월별로 조사한 결과, 안성베네스트골프장에서만 차이를 보여 2006년 7월에 가장 밀도가 높았다. 1971년에 개장한 동래베네스트골프장에서는 페어웨이와 러프 지역 간에 지렁이의 밀도는 차이가 없었으나 1999년 이후에 개장한 가평베네스트골프장과 안성베네스트골프장에서는 페어웨이에 비하여 러프의 지렁이 밀도가 높았다. 동일 골프장에서는 코스의 조성 년도가 오래된 곳일수록 지렁이의 밀도가 높았다. 식물 정유인 mustard oil(Brassica spp.)과 wintergreen oil(Gaultheria procumbens) 및 한약재 추출물(사군자: Quisqualis indica, 원화: Daphne genkwa, 흑축: Pharbitis nil, 건강: Zingiber officinale, 창이자: Xanthium strumarium), 차나무(Camellia sinensis) saponin을 이용하여 지렁이에 대한 독성을 조사한 결과, mustard oil과 wintergreen oil 및 tea saponin의 독성이 높았다. Pot 실험결과 12.4% 유효성분량 tea saponin 분말 500배 살포 시에 대조약제인 ethoprophos와 동일한 100%의 치사율을 보였다.

• Journal of Applied Biological Chemistry
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• 제66권
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• pp.122-127
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• 2023

심혈관 질환(CVD)은 전 세계적으로 주요 사망 원인으로써 갈수록 증가하는 추세이며, 혈관 손상이 발생하였을 때, 혈전이 과도하게 형성되는 것이 그 원인인 중 하나이다. 근래에 혈소판 억제를 통한 항혈전 물질에 대한 관심이 커지고 있으며 천연 생물활성 화합물을 사용함으로써 부작용을 줄이려는 노력이 이루어지고 있다. Flavonoid 중 하나로 알려진 hydroxygenkwanin(HGK)은 팥꽃나무(Daphne genkwa)에서 정제되는 물질로서 항균, 항염증 및 항암 효과가 있다고 알려져 있으며, 혈전증을 예방하는 조직 인자의 억제제 역할을 한다고 보고되었지만 항혈소판 효과와 그 작용기전에 대해서는 거의 알려지지 않았다. 본 연구를 통해 HGK가 collagen 유도의 사람 혈소판 응집에 미치는지 확인하였고, 그 작용 기전을 확인하였다. HGK은 혈소판 신호 전달 과정에서 PI3K/AKT 및 MAPK의 인산화를 억제하였고, ATP 및 serotonin 등의 혈소판 내 과립 분비를 감소하였다. . 또한, HGK는 cPLA₂의 인산화를 억제하며 응집 촉진물질인 TXA₂ 생성을 강하게 저해하였다. 결과적으로 응집 유도 물질인 collagen가 유도한 혈소판 응집을 86.36 µM의 IC₅₀로 강하게 억제하였다. 그러므로, 본 연구를 통해 HGK가 혈관 손상을 통해 일어나는 사람 혈소판의 활성화 및 응집을 억제하는 항혈전 물질로 가치가 있음을 분명히 하였다.

• 생명과학회지
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• 제12권6호
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• pp.649-653
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• 2002

본 조사지역은 행정상 거제시 일운면 와현리 남단 서이말등대가 위치한 해발 228.4 m고지 일대로서 2001년 8월 1일부터 2002년 7월 30일 까지 1년동안 6회에 걸쳐 식생과 식물상을 조사하여 현존식 생도와 군락조성표를 작성하였다. 본 조사지역에는 미국자리공, 주홍서나물, 별꽃아재비등 27종류의 귀화식물과 동백나무, 우묵사스레피, 메밀잣밤나무 등 30종류의 상록활엽수가 자생하였다. 식물군락은 동백나무군락, 모밀잣밤나무군락, 참식나무군락, 졸참나무군락, 굴참나무군락, 소사나무군락, 때죽나무관락, 곰솔군락, 상수리나무군락, 느티나무군락, 생달나무군락 등 총 11개 군락으로 나타났다. 전반적으로 천이의 거의 최종단계에 이르는 매우 양호한 상록활엽수림이 보존된 지역으로서 백서향, 갯취, 개족도리, 보춘화, 죽절초 등의 자생은 학술적, 자원적 가치가 높게 인정된다.

• Earthquakes and Structures
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• 제10권4호
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• pp.867-891
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• 2016

This paper addresses numerically the behavior of steel structures under Fire-after-Earthquake (FAE) loading. The study is focused on a four-storey library building and takes into account the damage that is induced in structural members due to earthquake. The basic objective is the assessment of both the fire-behavior and the fire-resistance of the structure in the case where the structure is damaged due to earthquake. The combined FAE scenarios involve two different stages: during the first stage, the structure is subjected to the ground motion record, while in the second stage the fire occurs. Different time-acceleration records are examined, each scaled to multiple levels of the Peak Ground Acceleration (PGA) in order to represent more severe earthquakes with lower probability of occurrence. In order to study in a systematic manner the behavior of the structure for the various FAE scenarios, a two-dimensional beam finite element model is developed, using the non-linear finite element analysis code MSC-MARC. The fire resistance of the structure is determined using rotational limits based on the ductility of structural members that are subjected to fire. These limits are temperature dependent and take into account the level of the structural damage at the end of the earthquake and the effect of geometric initial imperfections of structural members.

• Journal of Forest and Environmental Science
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• 제32권1호
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• pp.10-19
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• 2016

This study was carried out in the Boin and Miryousef regions in Baneh of Kordestan province, west of Iran. Both areas were divided into two parts including protected and unprotected areas. In each area, 20 $1000-m^2$ circular plots were established following a selective method. Tree and shrub species were identified and the number of these species was counted in each sampling plot. The results indicated that 7 trees, 4 shrubs and 109 herbaceous species were found in the studied areas, 40 herbaceous, 7 tree and 3 shrub species were present in protected area, while unprotected area had 16 herbaceous and 3 tree species. The highest value of diversity indices belonged to protected areas in all vegetation layers. In tree layer, Quercus brantii had the greatest value of SIV, whereas the lowest value belonged to Pistacia atlantica. In shrub layer, the highest and lowest values of SIV belonged to Daphne mezereum and Cerasus microcarpa, respectively. Finally, in herbaceous layer, Luzula spicata had highest value of SIV, and lowest value was belonged to Galium sp.

• Steel and Composite Structures
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• 제23권1호
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• pp.53-66
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• 2017

Structures submitted to Fire-After-Earthquake loading situations, are first experiencing inelastic deformations due to the seismic action and are then submitted to the thermal loading. This means that in the case of steel framed structures, at the starting point of the fire, plastic hinges have already been formed at the ends of the beams. The basic objective of this paper is the evaluation of the rotational capacity of steel I-section beams damaged due to prior earthquake loading, at increased temperatures. The study is conducted numerically and three-dimensional models are used in order to capture accurately the nonlinear behaviour of the steel beams. Different levels of earthquake-induced damage are examined in order to study the effect of the initial state of damage to the temperature-evolution of the rotational capacity. The study starts with the reference case where the beam is undamaged and in the sequel cyclic loading patterns are taken into account, which represent earthquakes loads of increasing magnitude. Additionally, the study extends to the evaluation of the ultimate plastic rotation of the steel beams which corresponds to the point where the rotational capacity of the beam is exhausted. The aforementioned value of rotation can be used as a criterion for the determination of the fire-resistance time of the structure in case of Fire-After-Earthquake situations.

• 한국환경복원기술학회지
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• 제18권4호
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• pp.43-62
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• 2015

The purpose of this study is to offer the raw data for management and conservation of Korean ecosystem by surveying the present conditions and characteristics of flora to select the ecological and landscape conservation area, Ilwolsan(Mt.), Korea. The numbers of flora in Mt. Ilwol were summarized as 582 taxa including 94 families, 307 genera, 508 species, 4 subspecies, 61 varieties and 9 formas. The rare plants were 15 taxa including Clematis koreana, Aristolochia contorta, Daphne pseudomezereum var. koreana, Iris odaesanensis and so forth. The Korean endemic plants were 14 taxa including Pseudostellaria coreana, Philadelphus schrenckii, Galium koreanum, Weigela subsessilis and so forth. The specific plants by floristic region were 29 taxa including Cimicifuga heracleifolia, Parasenecio firmus, Sorbaria sorbifolia var. stellipila, Acer mandshuricum, Syringa reticulata var. mandshurica and so forth. The naturalized plants were 22 taxa including Fallopia dumetorum, Rumex nipponicus, Trifolium repens, Sonchus asper, Phleum pratense and so forth. A set of important area is rare plant, Korean endemic plant, specific plant emerge a lot of areas.