• Journal of the Earthquake Engineering Society of Korea
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• v.17 no.5
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• pp.237-243
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• 2013

In the Korean Building Code (KBC), the Design Eccentricity involves the torsional amplification factor (TAF), and the inherent and accidental eccentricities. When a structure of less than 6-stories and assigned to seismic design category C or D is designed using equivalent static analysis method, both KBC-2006 and KBC-2009 use the TAF but apply different calculation methods for the of design eccentricity. The design eccentricity in KBC-2006 is calculated by multiplying the sum of inherent eccentricity and accidental eccentricity at each level by a TAF but that in KBC-2009 is calculated by multiplying only the accidental eccentricity by a TAF. In this paper, the damage indices of a building with planar structural irregularity designed by different design eccentricities are compared and the relationship between the earthquake damage and design eccentricity of the building is evaluated. On the basis of this study, the increment of design eccentricity results in the decrement of final eccentricity and global damage index of structure. It is observed that design eccentricity in KBC-2006 reduces the vulnerability of torsional irregular building compared to design eccentricity in KBC-2009.

• Molecules and Cells
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• v.43 no.2
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• pp.99-106
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• 2020

Cells are constantly exposed to endogenous and exogenous stresses that can result in DNA damage. In response, they have evolved complex pathways to maintain genomic integrity. RUNX family transcription factors (RUNX1, RUNX2, and RUNX3 in mammals) are master regulators of development and differentiation, and are frequently dysregulated in cancer. A growing body of research also implicates RUNX proteins as regulators of the DNA damage response, often acting in conjunction with the p53 and Fanconi anemia pathways. In this review, we discuss the functional role and mechanisms involved in RUNX factor mediated response to DNA damage and other cellular stresses. We highlight the impact of these new findings on our understanding of cancer predisposition associated with RUNX factor dysregulation and their implications for designing novel approaches to prevent cancer formation in affected individuals.

• Proceedings of the KSR Conference
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• 2002.10b
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• pp.1065-1073
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• 2002

A new damage identification technique using static displacement data is developed to assess the structural integrity of bridge structures. In the conventional damage assessment techniques using dynamic response, it is usually difficult to obtain a significant natural frequencies variation from the measured data because the natural frequencies variation is intrinsically not sensitive to the damage of a bridge. In this proposed identification method, the stiffness reduction of the bridges can be estimated using the static displacement data measured periodically and a specific loading test is not required. The static displacement data due to the dead load of the bridge structure can be measured by devices such as a laser displacement sensor. In this study, structural damage is represented by the reduction in the elastic modulus of the element. The damage factor of the element is introduced to estimate the stiffness reduction of the bridge under consideration. Finally, the proposed algorithm is verified using various numerical simulation and compared with other damage identification method. Also, the effect of noise and number of damaged elements on the identification are investigated. The results show that the proposed algorithm is efficient for damage identification of the bridges.

• Structural Engineering and Mechanics
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• v.33 no.3
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• pp.325-337
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• 2009

Structural damage detection, damage localization and severity estimation of jacket platforms, based on calculating modal strain energy is presented in this paper. In the structure, damage often causes a loss of stiffness in some elements, so modal parameters; mode shapes and natural frequencies, in the damaged structure are different from the undamaged state. Geometrical location of damage is detected by computing modal strain energy change ratio (MSECR) for each structural element, which elements with higher MSECR are suspected to be damaged. For each suspected damaged element, by computing cross-modal strain energy (CMSE), damage severity as the stiffness reduction factor -that represented the ratios between the element stiffness changes to the undamaged element stiffness- is estimated. Numerical studies are demonstrated for a three dimensional, single bay, four stories frame of the existing jacket platform, based on the synthetic data that generated from finite element model. It is observed that this method can be used for damage detection of this kind of structures.

• Korean Journal of Plant Resources
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• v.23 no.2
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• pp.172-178
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• 2010

This study was carried out to investigate abiotic and biotic environmental factors affecting homoharringtonine (HHT) contents of Cephalotaxus koreana, whereby, to provide basic information of high value-added industry production of HHT as a promising anti-cancer agent. For correlation between abiotic environmental factors (soil moisture, soil pH, habitat density and temperature) and HHT contents, the contents were highly correlated with soil moisture (0.77) and soil pH (-0.68). For multiple regression analysis of relationship between abiotic environmental factors (soil moisture and soil pH) and HHT contents, soil moisture appeared to be strongly affecting the contents relatively due to being significant at only its regression coefficient ($26.48^{***}$). For the effect of biotic environmental factors (damage index) affecting HHT contents, the contents was quadratic with equation of $H=278.23+1242D-398.87D^2$, also, damage index had strong effect on the contents. Finally, for the result of the most influencing an environmental factor on HHT contents, both damage index and soil moisture were suitable in second polynomial regression, also, damage index ($R^2=0.73^{***}$) was turned out to be more influencing factor than soil moisture ($R^2=0.67^{**}$) on HHT contents relatively. Therefore, we predict that HHT contents in the trees of Cephalotaxus koreana is produced as a chemical defense mechanism triggered by a stress-related damage of fungi or insects.

• Journal of Korean Society of Steel Construction
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• v.19 no.2
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• pp.211-221
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• 2007

A structural reliability analysis of fatigue truck model for fatigue failure of highway steel bridges was performed by applying the Miner's fatigue damage rule expressed as a function of various random variables affecting fatigue damage. Among the variables, the statistical parameters for equivalent moment, impact factor, and loadometer were obtained by analyzing recently measured domestic traffic data, whereas the parameters on fatigue strength, girder distribution factor, and headway factor of the measured data available in the literature were used. The effects of various fatigue truck models, fatigue life, ADTT, fatigue detail category, loadometer, and gross vehicle weight of fatigue truck on the reliability index of fatigue damage were analyzed. It is expected that the analytical results presented herein can be used as a basic background material in the calibration of both fatigue design truck and fatigue load factor of LRFD specification.

• Journal of Biosystems Engineering
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• v.32 no.6
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• pp.416-421
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• 2007

Physical damage to fruits and vegetables caused by shock degrades the value of product in the fresh market. In order to design a product/packaging system to protect the product, the G-factor to the product that causes shock damage needs to be determined. The shock fragility of organisms such as fruits with a concept correspondent to the G-factor of industrial products was calculated and we defined the allowable bio-shock fragility index as the value divided peak acceleration that was generated in safe drop height by standard acceleration of gravity. We did modeling for safe drop hight that would prevent fruits from damage by drop tests and tried to estimate the allowable bio-shock fragility index of pears and apples for optimum packaging design. The bio-shock fragility index of pears was in the range of $0.74{\sim}2.29\;G$, while apples had a slightly higher value than that of pears, of $0.51{\sim}2.98\;G$. This result shows accordance with the general fact that apples have a firmer structure and get less damage from the same impact. Based on this result, it is possible to create an optimum packaging design by providing a damage standard by impact.

• Smart Structures and Systems
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• v.29 no.1
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• pp.41-51
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• 2022

Cables are critical components of cable-stayed bridges. A structural health monitoring system provides real-time cable tension recording for cable health monitoring. However, the measurement data involve multiple sources of variability, i.e., varying environmental and operational factors, which increase the complexity of cable condition monitoring. In this study, a one-class classification method is developed for cable condition assessment using Bayesian factor analysis (FA). The single-peaked vehicle-induced cable tension is assumed to be relevant to vehicle positions and weights. The Bayesian FA is adopted to establish the correlation model between cable tensions and vehicles. Vehicle weights are assumed to be latent variables and the influences of different transverse positions are quantified by coefficient parameters. The Bayesian theorem is employed to estimate the parameters and variables automatically, and the damage index is defined on the basis of the well-trained model. The proposed method is applied to one cable-stayed bridge for cable damage detection. Significant deviations of the damage indices of Cable SJS11 were observed, indicating a damaged condition in 2011. This study develops a novel method to evaluate the health condition of individual cable using the FA in the Bayesian framework. Only vehicle-induced cable tensions are used and there is no need to monitor the vehicles. The entire process, including the data pre-processing, model training and damage index calculation of one cable, takes only 35 s, which is highly efficient.

• Proceedings of the Korean Society for Technology of Plasticity Conference
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• 2003.10a
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• pp.291-295
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• 2003

The occurrence of ductile fracture is the working limit of many metal forming processes. It is necessary to predict the criteria and to apply the condition in a process design. Over the years. the way for clarifying conditions have been studied and presented. However such a way needs lots of experiments and analysis. In this study, in order to determine the critical damage value of a used material Cu 4N, it was performed a tensile test and FEM analysis by using DEFORM 2D. For applying the obtained critical damage value it was also performed a upsetting test by using DEFORM 2D. The way of determining a critical damage value which is presented in this study will make possible to find easily it which is one of the working limit factor. And the way of determining a critical damage value will make possible to find in multi-pass drawing process.

• KCI Concrete Journal
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• v.13 no.2
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• pp.26-32
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• 2001

A simple expected damage cost model is developed and a systematic approach to evaluate the economic effects of seismic hazards to reinforced concrete structures is presented. An expected damage cost function during a specific lifetime is modeled by a Poisson's process with uniform continuous cash flow assumption. It is possible that the proposed method can decouple the damage cost effect from random earthquake events. Thus, expected damage cost function can be formulated as a combination of three independent terms; a present worth factor of Poisson's process, a damage cost interpolation function and a mean occurrence rate of earthquake intensity. The validity of the proposed method is demonstrated by a comparative study of LCC evaluations with the previous study.