• 한국지진공학회논문집
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• 제17권5호
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• pp.237-243
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• 2013

In the Korean Building Code (KBC), the Design Eccentricity involves the torsional amplification factor (TAF), and the inherent and accidental eccentricities. When a structure of less than 6-stories and assigned to seismic design category C or D is designed using equivalent static analysis method, both KBC-2006 and KBC-2009 use the TAF but apply different calculation methods for the of design eccentricity. The design eccentricity in KBC-2006 is calculated by multiplying the sum of inherent eccentricity and accidental eccentricity at each level by a TAF but that in KBC-2009 is calculated by multiplying only the accidental eccentricity by a TAF. In this paper, the damage indices of a building with planar structural irregularity designed by different design eccentricities are compared and the relationship between the earthquake damage and design eccentricity of the building is evaluated. On the basis of this study, the increment of design eccentricity results in the decrement of final eccentricity and global damage index of structure. It is observed that design eccentricity in KBC-2006 reduces the vulnerability of torsional irregular building compared to design eccentricity in KBC-2009.

• Molecules and Cells
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• 제43권2호
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• pp.99-106
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• 2020

Cells are constantly exposed to endogenous and exogenous stresses that can result in DNA damage. In response, they have evolved complex pathways to maintain genomic integrity. RUNX family transcription factors (RUNX1, RUNX2, and RUNX3 in mammals) are master regulators of development and differentiation, and are frequently dysregulated in cancer. A growing body of research also implicates RUNX proteins as regulators of the DNA damage response, often acting in conjunction with the p53 and Fanconi anemia pathways. In this review, we discuss the functional role and mechanisms involved in RUNX factor mediated response to DNA damage and other cellular stresses. We highlight the impact of these new findings on our understanding of cancer predisposition associated with RUNX factor dysregulation and their implications for designing novel approaches to prevent cancer formation in affected individuals.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2002년도 추계학술대회 논문집(II)
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• pp.1065-1073
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• 2002

A new damage identification technique using static displacement data is developed to assess the structural integrity of bridge structures. In the conventional damage assessment techniques using dynamic response, it is usually difficult to obtain a significant natural frequencies variation from the measured data because the natural frequencies variation is intrinsically not sensitive to the damage of a bridge. In this proposed identification method, the stiffness reduction of the bridges can be estimated using the static displacement data measured periodically and a specific loading test is not required. The static displacement data due to the dead load of the bridge structure can be measured by devices such as a laser displacement sensor. In this study, structural damage is represented by the reduction in the elastic modulus of the element. The damage factor of the element is introduced to estimate the stiffness reduction of the bridge under consideration. Finally, the proposed algorithm is verified using various numerical simulation and compared with other damage identification method. Also, the effect of noise and number of damaged elements on the identification are investigated. The results show that the proposed algorithm is efficient for damage identification of the bridges.

• Structural Engineering and Mechanics
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• 제33권3호
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• pp.325-337
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• 2009

Structural damage detection, damage localization and severity estimation of jacket platforms, based on calculating modal strain energy is presented in this paper. In the structure, damage often causes a loss of stiffness in some elements, so modal parameters; mode shapes and natural frequencies, in the damaged structure are different from the undamaged state. Geometrical location of damage is detected by computing modal strain energy change ratio (MSECR) for each structural element, which elements with higher MSECR are suspected to be damaged. For each suspected damaged element, by computing cross-modal strain energy (CMSE), damage severity as the stiffness reduction factor -that represented the ratios between the element stiffness changes to the undamaged element stiffness- is estimated. Numerical studies are demonstrated for a three dimensional, single bay, four stories frame of the existing jacket platform, based on the synthetic data that generated from finite element model. It is observed that this method can be used for damage detection of this kind of structures.

• 한국자원식물학회지
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• 제23권2호
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• pp.172-178
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• 2010

천연집단에 서식하는 개비자나무 개체들을 이용해 무생물 및 생물적 환경인자가homoharringtonine(HHT) 함량에 미치는 영향을 조사하여 향후 항암제 가능성이 있는 HHT의 고부가가치 산업적인 생산이 기대되는 연구에 기초자료를 제공하고자 본 연구를 수행하였다. 무생물적 환경인자(토양습도, 토양pH, 서식밀도, 기온)와 HHT 함량과의 상관관계에 있어 HHT 는 토양습도(0.77)와 토양pH(-0.68)에서 높은 상관을 보였다. 고도에 따른 무생물적 환경인자 (토양습도, 토양pH)와 HHT 의 함량 관계에 관해 다중회귀 분석을 실시한 결과, 토양 습도의 회귀계수($26.48^{***}$) 만 유의하여 토양 습도가 상대적으로 HHT 함량에 높은 영향을 미치는 것으로 나타났다. 생물적 환경인자(damage index)에 따른 HHT 함량에 미치는 영향을 살펴 본 결과, HHT는 2차곡선회귀적으로 증가하다 감소하는($H=278.23+1242D-398.87D^2$) 경향을 보였고 damage index는 HHT 함량에 높은 영향을 미치는 것으로 분석되었다. 마지막으로 HHT 의 함량에 영향을 미치는 최적환경인자를 분석한 결과, damage index와 토양 습도 모두가 2차다항회귀식으로 가장 적합하였고 결정계수는 각각 0.73와 0.67로 damage index가 상대적으로 HHT 함량에 높은 영향을 미치는 것으로 나타났다. 이는 섭식자 또는 균류와 같은 스트레스로 인한 방어기작이 HHT 의 생성에 높은 영향을 미치는 것으로 판단된다.

• 한국강구조학회 논문집
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• 제19권2호
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• pp.211-221
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• 2007

교량의 피로파괴에 대한 Miner의 피로손상법칙을 적용하여 여러 확률변수로 표현된 피로파괴 한계상태함수에 대한 신뢰도해석을 국내에서 측정된 통행차량의 통계적 특성을 반영하여 수행하였다. 신뢰도지수의 산정에 필요한 확률변수 가운데 등가모멘트, 충격계수비, 등가하중비는 국내의 최근 측정자료를 분석하여 통계치를 산정하였으며, 피로강도, 활하중 횡분배비, 연행하중비는 국외에서 측정된 문헌자료의 통계치를 적용하였다. 신뢰도해석을 통하여 피로설계트럭의 종류, 교량수명, ADTT, 피로상세, 등가하중비, 피로설계트럭의 총중량 등의 피로손상에 관련된 여러 파라미터가 신뢰도지수에 미치는 영향을 분석하였다. 본 논문의 피로파괴에 대한 신뢰도해석 결과는 국내 LRFD 설계기준의 피로설계트럭모형과 피로한계상태의 하중계수를 결정할 때 기초 자료로 이용할 수 있을 것으로 판단된다.

• Journal of Biosystems Engineering
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• 제32권6호
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• pp.416-421
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• 2007

Physical damage to fruits and vegetables caused by shock degrades the value of product in the fresh market. In order to design a product/packaging system to protect the product, the G-factor to the product that causes shock damage needs to be determined. The shock fragility of organisms such as fruits with a concept correspondent to the G-factor of industrial products was calculated and we defined the allowable bio-shock fragility index as the value divided peak acceleration that was generated in safe drop height by standard acceleration of gravity. We did modeling for safe drop hight that would prevent fruits from damage by drop tests and tried to estimate the allowable bio-shock fragility index of pears and apples for optimum packaging design. The bio-shock fragility index of pears was in the range of $0.74{\sim}2.29\;G$, while apples had a slightly higher value than that of pears, of $0.51{\sim}2.98\;G$. This result shows accordance with the general fact that apples have a firmer structure and get less damage from the same impact. Based on this result, it is possible to create an optimum packaging design by providing a damage standard by impact.

• Smart Structures and Systems
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• 제29권1호
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• pp.41-51
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• 2022

Cables are critical components of cable-stayed bridges. A structural health monitoring system provides real-time cable tension recording for cable health monitoring. However, the measurement data involve multiple sources of variability, i.e., varying environmental and operational factors, which increase the complexity of cable condition monitoring. In this study, a one-class classification method is developed for cable condition assessment using Bayesian factor analysis (FA). The single-peaked vehicle-induced cable tension is assumed to be relevant to vehicle positions and weights. The Bayesian FA is adopted to establish the correlation model between cable tensions and vehicles. Vehicle weights are assumed to be latent variables and the influences of different transverse positions are quantified by coefficient parameters. The Bayesian theorem is employed to estimate the parameters and variables automatically, and the damage index is defined on the basis of the well-trained model. The proposed method is applied to one cable-stayed bridge for cable damage detection. Significant deviations of the damage indices of Cable SJS11 were observed, indicating a damaged condition in 2011. This study develops a novel method to evaluate the health condition of individual cable using the FA in the Bayesian framework. Only vehicle-induced cable tensions are used and there is no need to monitor the vehicles. The entire process, including the data pre-processing, model training and damage index calculation of one cable, takes only 35 s, which is highly efficient.

• 한국소성가공학회:학술대회논문집
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• 한국소성가공학회 2003년도 추계학술대회논문집
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• pp.291-295
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• 2003

The occurrence of ductile fracture is the working limit of many metal forming processes. It is necessary to predict the criteria and to apply the condition in a process design. Over the years. the way for clarifying conditions have been studied and presented. However such a way needs lots of experiments and analysis. In this study, in order to determine the critical damage value of a used material Cu 4N, it was performed a tensile test and FEM analysis by using DEFORM 2D. For applying the obtained critical damage value it was also performed a upsetting test by using DEFORM 2D. The way of determining a critical damage value which is presented in this study will make possible to find easily it which is one of the working limit factor. And the way of determining a critical damage value will make possible to find in multi-pass drawing process.

• KCI Concrete Journal
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• 제13권2호
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• pp.26-32
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• 2001

A simple expected damage cost model is developed and a systematic approach to evaluate the economic effects of seismic hazards to reinforced concrete structures is presented. An expected damage cost function during a specific lifetime is modeled by a Poisson's process with uniform continuous cash flow assumption. It is possible that the proposed method can decouple the damage cost effect from random earthquake events. Thus, expected damage cost function can be formulated as a combination of three independent terms; a present worth factor of Poisson's process, a damage cost interpolation function and a mean occurrence rate of earthquake intensity. The validity of the proposed method is demonstrated by a comparative study of LCC evaluations with the previous study.