• 대한한방소아과학회지
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• 제18권1호
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• pp.193-206
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• 2004

Objective: The study aimed to evaluate the anti-stress effect of YST on the cold-stressed Mice. Method: The experimental animals were stressed in cold room ($4{\pm}0.5^{\circ}C$) for 1 hour in a day during 2weeks, and administerd 115mg/100g YST extract for 2weeks before stress. For 2weeks, we conducted a research about the change of weight and content of norepinephrine, epinephrine, dopamine, cortisol and GOT, GPT in the mice serum. Results: YST significantly inhibited the decrease of body weight induced by stress, compared with the control group. YST had no significant decreasing effect on the change of content of the serum GOT But decreased the content of the serum GPT. YST decreased the content of the serum cortisol. YST decreased the content of the serum dopamine a little and decreased the content of the serum epinephrine significantly. Conclusion: According to the above results, it is concluded that YST will be useful as a remedy against stress disease.

• 동의생리병리학회지
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• 제16권4호
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• pp.667-673
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• 2002

The purpose of this study was to investigate the effect of Kamisamchulsamja-tang (KSST) water extract on the antitumor activity. The results were summarized as follows: KSST extract exhibited a weak cytotoxicity against HT1080, A549, SK-OV-3, B16-F10 and SK-MEL-2 cells. KSST extract showed a inhibitoty effect on DNA topoisomerase I from calf thymus in a dose-dependent manner. Also, KSST extract showed antiadhesive effect on HT1080 cells but didn't showed on A549 cells to complex extracellular matrix. In pumonary colonization assay, a number of colonies in the lungs were decreased significantly in KSST treated group as compared with control group. In vitro neovascularization assays, angiogenesis was significantly inhibited in KSST treated group than control group. In CAM assay, KSST extract inhibited angiogenesis significantly at 15㎍/egg concentration as compared with control. From the above results it was concluded that KSST showed antitumor effect through the antimetastatic effect. So it is expected to be clinically helpful on the prevention of metastasis of cancer.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2004년도 춘계학술대회 논문집
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• pp.1007-1013
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• 2004

A three-arch NATM tunnel with a total length of 53.5m has been constructed for a metropolitan subway station in Daejon, Korea. The tunnel, whose crown is located 22m below the ground, crosses the old Daejon station underneath. Since the tunnel comprises a very large section (10${\times}$28 m; largest in Korea), it shows complicated mechanical behaviors, especially near portal, due to its short length relative to width. As far as its construction step is concerned, the center tunnel is excavated with pre-excavated pilot tunnel, which is a unique feature of this tunnel (first in Korea) to secure safety during construction and prevent excessive settlements. The both side tunnels are then excavated along with the center tunnel. Since significant amount of settlement was predictable from the design stage, extensive monitoring was performed during construction. During excavation of the side tunnels, unexpected large settlements up to ${\~}$140mm (estimated 41.8 mm at design stage) was measured at the center tunnel. In this paper, we study the causes of this unusually large ground settlement. We believe that the extra-wide tunnel excavation increases the stress influence zone of portal in longitudinal direction and consequently add more settlements to the existing due to excavation and consolidation.

• 대한한의학원전학회지
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• 제23권5호
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• pp.55-66
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• 2010

The medicinal part of Treasured Mirror of Eastern Medicine("東醫寶鑑" "湯液編") is based on Classified Emergency Materia Medica("證類本草"), Compendium of Prescriptions from the Countryside("鄕藥集成方"). But it distinguished materia medica of countryside(鄕藥) from materia medica of China(唐藥) and properly selected the sentences of them by actual medical circumstances in Korean peninsula. Especially upon assortment of medical herbs, the medicinal part of Treasured Mirror of Eastern Medicine added the part of Water, Earth, Metal, and divided the part of Fish & Bug, Jade & Stone into Fish, Bug, Jade, Stone part. Moreover, it abolished the three grade classification adopted in Classified Emergency Materia Medica, Compendium of Prescriptions from the Countryside and attempted a new approach on itemization; 'representative herb' and 'secondary herb'. Hence, medicinal part of Treasured Mirror of Eastern Medicine should be evaluated as the 'settling in of Chinese medicine with autonomous interpretation, other than 'the fusion of prescriptions from countryside and Chinese medicine.

• International Journal of Precision Engineering and Manufacturing
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• 제3권1호
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• pp.26-32
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• 2002

Laser direct patterning of the coated photoresist (PMER-NSG31B) layer was studied to make halftone dots on the gravure printing roll. The selective laser hardening of the photoresist by Ar-ion laser(wavelength: 333.6∼363.8 nm) was controlled by the A/O modulator. The coating thickness in the range of 5∼11㎛ could be obtained by using the up-down directional moving device along the vertically located roll. The width, thickness and hardness of the hardened lines farmed under the laser power of 200∼260mW and irradiation time of 4.4∼6.6 $\mu$ sec/point were investigated after developing. The hardened width increased as the coating thickness increased. Though the hardened thickness was changed due to the effect of the developing solution, the hardened layer showed good resistance to the scratching of 2H pencil. Also, the hardened minimum line width of 10㎛ could be obtained. The change of line width was also found after etching, and the minimum line widths of 6㎛ could be obtained. The hardened lines showed the good resistance to the etching solution. Finally, the experimental data could be applied to make gravure halftone dots using the developed imaging process, successfully.

• 대한한의학원전학회지
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• 제24권3호
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• pp.49-64
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• 2011

Objectives : This paper is written to identify the origin of the nature of medicinals in Rhymes(藥性歌) in Korean medical books and to analyze their creativity. Methods : We analysed the nature of medicinals in Rhymes contained Chinese and Korean medical books. Results : The Korean medical book New Edition on Universal Relife(濟衆新編), published by Chosun government, recorded the nature of medicinals in Rhymes Recovery from All Ailments(萬病回春) mostly untouched. It can be evaluated the early model of Chosun's nature of medicinals in Rhymes. New Edition on Universal Relife, Gains and Losses of Medical Orthodoxy(醫宗損益) added new rhymes using familiar herbs and vegetables got easily, most new rhymes founded medicinal part of Treasured Mirror of Eastern Medicine (東醫寶鑑). Conclusions : The nature of medicinals in Rhymes is an approach to simplify and improve access on herbal medicine, and is quoted in various forms throughout medical books of Chosun. The entitling it as 'scientific research of herbal medicine based on the nature of medicinals in Rhymes' can clearly be seen as description about superficial result, to persist the decadence of Chosun medicine.

• Restorative Dentistry and Endodontics
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• 제29권4호
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• pp.346-352
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• 2004

The purpose of present study was to evaluate the polymerization shrinkage stress and cuspal deflection in maxillary premolars resulting from polymerization shrinkage of composites and compomers. Composites and compomers which were used in this study were as follows: Dyract AP, Z100, Surefil. Pyramid, Synergy Compact, Heliomolar, Heliomolar HB, and Compoglass F. For measuring of polymerization shrinkage stress, Stress measuring machine (R&B, Daejon, Korea) was used. One-way ANOVA analysis with Duncan's multiple comparison test were used to determine significant differences between the materials. For measuring of cuspal deflection of tooth, MOD cavities were prepared in 10 extracted maxillary premolars. And reduction of intercuspal distance was measured by strain measuring machine (R&B, Daejon, Korea) One-way ANOVA analysis with Turkey test were used to determine significant differences between the materials. Polymerization shrinkage stress is $\mathbb{\ulcorner}$Heliomolar, Z100, Pyramid < Synergy Compact Compoglass F < Dyract AP < Heliomolr HB, surefil$\mathbb{\lrcorner}$ (P < 0.05). And cuspal delfelction is $\mathbb{\ulcorner}$Z100, Heliomolar, Heliomolar HB, Synergy Compact Surefil. < Compoglass F < Pyramid, Dyract AP$\mathbb{\lrcorner}$ (P < 0.05). Measurements of ploymerization shrinkage stress and those of cuspal deflection of the teeth was different. There is no correlation between polymerization shrinkage stress and cuspal deflection of the teeth(p > 0.05).

• 척추신경추나의학회지
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• 제1권2호
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• pp.111-123
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• 2006

Objectives: This study is performed to evaluate the clinical effect of chuna therapy on the neck pain associated with kyphotic cervical curvature. Methods: This study carried out on three patients with neck pain & kyphotic cervical curvature who have received treatment in Depar1ment of Oriental Rehabilitation Medicine, Daejon Oriental Hospital of Daejon University from 28th July 2006 to 3th November 2006. Pre and post treatment, We evaluated the cervical angle, Jackson's angle, Jochumsen method, Ishihara index, VAS and effective score of treatment. Results & Conclusions: Two patients who received Chuna treatment recovered cervical curvature and improved neck pain. But One patient who dosen't received Chuna treatment was no improvement in cervical curvature & neck pain.

• 동의생리병리학회지
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• 제16권3호
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• pp.472-478
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• 2002

The purpose of this study was to investigate the effect of Kamigedang-tang(KGDT) water extract on the antitumor and anti metastatic activity. The results were summarized as follows: KGDT extracts exhibited a significant cytotoxicity against P388, SK-MEL-2, SK-OV-3, and B16-F10 cell lines and showed significant inhibitoty effect on DNA topoisomerase I from calf thymus. The T/C% was 122.9% in KGDT treated group in S-180 bearing ICR mice. Also, KGDT extracts exhibited efficient affect adhesive effect of A549 cell to complex extracellular matrix. In CAM assay, KGDT extracts inhibited angiogenesis at 15㎍/egg concentration insignificantly as compared with control. These results suggested that KGDT extracts might be usefully applied for prevention and treatement of cancer.

• 대한세포병리학회지
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• 제13권1호
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• pp.33-37
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• 2002

We report two different types of thyroid lymphoma associated with Hashimoto's thyroiditis. Both showed autoantibodies and were compatible with Hashimoto's thyroiditis according to their clinical backgrounds. A 76-year-old female noted a painless, rapidly growing mass in her neck which was diagnosed as diffuse non-Hodgkin's lymphoma, large cell type, after the fine needle aspiration cytology of the thyroid. She underwent chemo-radiotherapy and is free of the disease 10 months after diagnosis. The other patient, a 73-year-old female with a diffuse golfer, was diagnosed on fine needle aspiration cytology as having Hashimoto's thyroiditis. Three years later she developed a hard nodular growth in the both lobes of the thyroid. This was subjected to fine needle aspiration cytology and needle biopsy and was diagnosed as a MALT lymphoma. She refused any treatment and died 12 months after the diagnosis.