• Proceedings of the KSR Conference
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• 2010.06a
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• pp.234-240
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• 2010

Display Unit(DU) of TCMS is very useful device display many data for operation and maintenance graphically. At This Time, rolling stock is reducing the wiring and size of desk for cutting down on their cost and making light weight. Dual Du(Display Unit) of TCMS could make the desk of cab simply by integrating cab's switches and gauges. Dual DU is not only can reduce the wiring and simplify desk of cab but also can making system of TCMS reliable by including backup function each other. For this reason. In this paper, advantages, application and example analysis of Dual DU of TCMS for rolling stock are described through the ongoing projects.

• Korean Journal of Pharmacognosy
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• v.42 no.1
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• pp.6-8
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• 2011

'BaegDuOng(白頭翁)' is one of the Chinese crude drugs used mainly as a pruritus, arthritis, cough and abdominal pain. The botanical origin of the crude drug has never been studied pharmacognostically. To clarify the botanical origin of 'BaegDuOng', the morphological and anatomical characteristics of Pulsatilla species growing in Korea, i.e. Pulsatilla koreana Nakai and P. cernua (Thunb.) Spreng. were studied. As a result, BaegDuOng from Korea was proved to be the root of Pulsatilla koreana.

• Journal of Korea Technical Association of The Pulp and Paper Industry
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• v.39 no.5
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• pp.58-63
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• 2007

This paper sums up all the different steps broached in this project : The NIR spectroscopy technique has been studied and implemented at CTP using a mobile spectrometer device and different optical materials. Methods, based on statistical data analysis (in particular PLS regressions), have been investigated. A laboratory "prototype" using these techniques and methods has been developed in order to control the recovered papers quality, in terms of humidity percentage and sample composition (paper, board, contaminants).

• Journal of the Korean Society of Costume
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• v.22
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• pp.243-262
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• 1994

L'niteret majeur de cette etude reside dans I'interpretation des images vestimentaired au Moyen-Age en France sur le plan esthetique et religieux. Comme d'interessantes hypotheses de tra-vail les images religieuses temoignent de la transformation de I'esprit religieux, artistique mais aussistyle de vie, de la mode et du gout a l'epoque segeuriale. D'apres les icons de la ste. Vierge, on peut y noter de multiples sources d'influence. le style autochtone fancais-I'art courtois le style gothique intenational les types de repre'sentation siennoise le Realisme neerlandais le Naturalisme italien Comme le role du vetement d'apres les icons de la ste. Marie le Moye n d'identification de la ste. Marie L'Objet de connexion entre les figures et I'architecture L'Element decoratif dans la peinture L'Intermediaire expressif et approfondi du theme On peut aussi dresser I'iconographie et le symbolisme vestimentairedans le monde chretien.

• Journal of English Language & Literature
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• v.57 no.3
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• pp.391-411
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• 2011

This paper examines Du Boisian critique of American exceptionalism through a close textual analysis of his writings from early essays to later works. As an attempt to respond to the persistent grip American exceptionalism has on both the academia and the intellectual world at large, this paper tries to fill in the gaps within the discourse of American exceptionalism by exploring the works of one of the most towering American intellectual figures, and suggests that the discourse of American exceptionalism has remained within the purview of white scholars. Although at times inconsistent and contradictory, Du Bois's trenchant critique of American civilization and Western imperialism deconstructs the original ideals of America, creating more than a fissure in the ideology/hegemony/state fantasy of American exceptionalism. I argue that Du Boisian critique of American exceptionalism shows its violent marginalization and racialization based on white supremacy. Du Boisian critique should be a cautionary tale for those scholars who talk of "reform" or "replenishment" or even who occlude the possibility that American exceptionalism has not always functioned as a "state fantasy" by assuming its absolute blinding powers.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.6
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• pp.2835-2839
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• 2014

Prostate cancer is one of the most prevalent malignant cancers in men. The isoflavone formononetin is a main active component of red clover plants. In the present study, we assessed the effect of formononetin on human prostate cancer DU-145 cells in vitro, and elucidated posssible mechanisms. DU-145 cells were treated with different concentrations of formononetin and cell proliferation was assessed by MTT assay, cell apoptosis by Hoechst 33258 and flow cytometry, and protein levels of RASD1, Bcl-2 and Bax by Western blotting. The results showed that formononetin inhibited the proliferation of DU-145 cells in a dose-dependent manner. DU-145 cells treated with different concentrations of formononetin displayed obvious morphological changes of apoptosis under fluorescence microscopy. In addition, formononetin increased the proportion of early apoptotic DU-145 cells, down-regulated the protein levels of Bcl-2 and up-regulated those of RASD1 and Bax. The level of RASD1 reached its maximum at 48h post-treatment, and rapidly decreased thereafter. Together, we present evidence that formononetin triggered cell apoptosis through the mitochondrial apoptotic pathway by up-regulating RASD1.

• BMB Reports
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• v.50 no.9
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• pp.466-471
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• 2017

The results of this study show that c-Jun N-terminal kinase (JNK) activation was associated with the enhancement of docetaxel-induced cytotoxicity by simvastatin in DU145 human prostate cancer cells. To better understand the basic molecular mechanisms, we investigated simvastatin-regulated targets during simvastatin-induced cell death in DU145 cells using two-dimensional (2D) proteomic analysis. Thus, vimentin, Ras-related protein Rab-1B (RAB1B), cytoplasmic hydroxymethylglutaryl-CoA synthase (cHMGCS), thioredoxin domain-containing protein 5 (TXNDC5), heterogeneous nuclear ribonucleoprotein K (hnRNP K), N-myc downstream-regulated gene 1 (NDRG1), and isopentenyl-diphosphate Delta-isomerase 1 (IDI1) protein spots were identified as simvastatin-regulated targets involved in DU145 cell death signaling pathways. Moreover, the JNK inhibitor SP600125 significantly inhibited the upregulation of NDRG1 and IDI protein levels by combination treatment of docetaxel and simvastatin. These results suggest that NDRG1 and IDI could at least play an important role in DU145 cell death signaling as simvastatinregulated targets associated with JNK activation.

• Toxicological Research
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• v.18 no.2
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• pp.183-190
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• 2002

The mechanism by which catechin-mediated cytotoxicity against tumor cells remains to be elusive. To elucidate the mechanical mights of anti-tumor effects, (-)epigallocatechin-gallate (EGCG) of catechin was applied to human prostate cancer DU 145 cells. Cell viability was measured by crystal violet staining. Cell lysates were wed to measure the catalytic activity of caspases by using fluorogenic peptide: Ac-DEVD-AMC for caspase-3 protease, Z-IETD-AFC for caspase-8 protease, Ac-LEHD-AFC for caspase-9 protease as substrates. The equal amounts of protein from cell lysate was separated on SDS-PAGE and analyzed by western blotting with anti-Fas antibody, anti-FasL antibody, anti-BCL2 antibody and anti-Bax antibody. (-)EGCG induced the death of DUl45 cells, which was revealed as apoptosis shown by DNA fragmentation. (-)EGCG induced the activation of caspase family cysteine proteases including caspase-3, -8 and -9 proteases in DU145 cells. Also, (-)EGCG increased the expression of Fas and Fas ligand (FasL) protein in DU145 colls. The expression level of BCL2 was decreased in (-)EGCG treated DU145 cells, whereas Bax protein was increased in a time-dependent manner. We suggest that (-)EGCG-induced apoptosis of DU145 cells is mediated by signaling pathway involving caspase family cysteine protease, mitochondrial BCL2-family protein and Fas/FasL.

• Journal of the Korean Society of Costume
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• v.60 no.1
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• pp.76-90
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• 2010

Gwa-du(裹肚), name of a garment, appears often from documentary records of Joseon Dynasty. It is assumed as one of the upper garments for men, and according to the record, it was worn as a set with Dan-ryung(團領), Dap-ho(搭胡), Chul-rik(帖裏), Han-sam(汗衫), pants and socks. After the Japanese Invasion of Korea in the 17th century, it changes to a shape of wrapping clothes with straps at four corners, and used to cover the stomach of a corpse like sash. From 16th-17th century, before the Japanese Invasion of Korea, the excavated costume shows a clothing which takes a role of Jegori, longer than Han-sam(汗衫) and shorter than Po(袍). In this study, this clothing is called Gwa-du(裹肚). This study examined the usage and shape of Kwa-du from some documentary records- "朝鮮王朝實錄-The Annals of the Joseon Dynasty", "禮書- Book of Manners", "宮中件記- Googjoonghalkee, recording court goods and commodities lists" and more with actual clothing. Kwa-du is presumed to have changed to men's Jegori So-chang-ui(小氅衣) after 17th century.

• Journal of The Korean Society of Integrative Medicine
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• v.8 no.4
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• pp.59-66
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• 2020

Purpose : This study aimed to present normative data for older Korean adults completing the Yonsei dual task cognitive screening test (Y-DuCog) and identify changes in cognitive function on the Montreal Cognitive Assessment - Korean (MoCA-K) with age. Methods : From May 2019 to August 2019, 195 healthy adults aged ≥60 years participated in this study. All participants completed the Y-DuCog to assess their dual-task performance and the MoCA-K to assess their cognitive function. Participants were divided into three groups based on their age: 60~69 years, 70~79 years, and ≥80 years. Results : The results of the Y-DuCog showed that dual-task performance time, effect, and correct response rate decreased significantly with age (p<.001). Scores from the three groups showed differences on all items (p<.001). Cognitive function on the MoCA-K also decreased significantly with age (mean score ± standard deviation [SD]; 27.33 ± 2.61 in subjects aged 60~69 years; 24.82 ± 3.20 in subjects aged 70~79 years; and 22.10 ± 4.91 in subjects aged ≥80 years; p<.001). Conclusions : Occupational therapists should be aware of the decline in cognitive function and dual-task performance time, effect, and correct response rate in older adults and consider interventions to treat this decline. Further studies are needed with larger groups of participants to examine factors, such as sex and education, that may impact dual-task performance and cognitive function.