• Asian Pacific Journal of Cancer Prevention
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• 제14권12호
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• pp.7737-7741
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• 2013

Background: Human papilloma virus infection is associated with genesis and malignant potential of cervical cancer. E6 and E7 oncogens are known to bind to p53 and retinoblastoma gene products, abrogating their functions as tumor suppressors, leading to an abnormal cell cycle machinery. Roles of the p53 homolog p63 have also been postulated, E6 expression leading to TAp63b degradation allowing anchorage independent growth. Molecular studies correlated with clinicopathological factors are important to determine prognosis and treatment strategies, but results have been controversial and need to be clarified. Aim: To investigate expression of p53 and p63 in cervical squamous cell carcinomas in correlation with age, FIGO staging, morphology, and cancer cell proliferation. Materials and Methods: Expression of p53 and p63 immunohistochemical staining in a total of 56 paraffin-embedded tissues of cervical squamous cell carcinomas from Dr. Sardjito General Hospital Indonesia, was evaluated for correlation with clinicopathological parameters. The Mann-Whitney test was used to compare the percentage of p53 and p63 expression with patient age, FIGO staging and morphology and to compare mean p53 and p63 expression. The Spearman correlation test was applied to correlate p53 and p63 expression with that of Ki-67. A p-value of <0.05 was considered statistically significant. Results: There were significant associations between p53 expression with age (p=0.019) and FIGO staging (p=0.026), but not with with morphology or Ki-67 expression. There were no links between p63 expression and age, morphology, FIGO staging or Ki-67. Conclusions: This study indicated that p53 has a prognostic value in cervical squamous cell carcinomas given the relation with FIGO staging.

• 한국방사성폐기물학회:학술대회논문집
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• 한국방사성폐기물학회 2007년도 학술논문요약집
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• pp.190-191
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• 2007

Cleanout of the F Reactor Fuel Storage Basin (FSB) is an element of the FSB decontamination and decommissioning (D&D) and is required to complete interim safe storage (ISS) of the F Reactor. Following reactor shutdown and in preparation for a deactivation layaway action in 1970, the water level in the FReactor FSB was reduced to approximately 0.6 m (2 ft) over t]to floor. Basin components and other miscellaneous items were left or placed in the FSB. The item placement was performed with a sense of finality, and no attempt was made to place the items in an orderly manner. The F Reactor FSB was then filled to grade level with 6(20of local surface material (essentially a fine sand). The reactor FSB backfill cleanout has the potential of having to remove spent nuclear fuel (SNF) that may have been left unintentionally. Based on previous cleanout of six water-filled FSBs with similar designs (i.e., the B, C, D, and DR FSBs in the 1980's), it was estimated that up to five SNF elements could be discovered in the F FSB (I). In reality about 17 full SNF elements were found in the excavation. This paper covers the technical and programmatic challenges of performing this decommissioning effort with some of the controls used for SNF management. The paper also will highlight how many various technologies were married into a complete package to address the issue at hand and show how no one tools could complete the job, but combined, good progress is being made.

• 한국재료학회지
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• 제9권4호
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• pp.355-361
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• 1999

가용성 폴리이마드 주쇄에 Disperse-Red 1 크로모포를 공유결합 시킨 옆사술계 비선형 전기광학 고분자를 합성하였다. 합성된 고분자의 유리전이온도 빛 열분해온도 는 각각 $225^{\circ}C, 310^{\circ}C$이었으며 광통신 파장에서 광학적으로 투명하였다. $100 V/\mu\textrm{m}$의 전기장으로 폴링했을 때, 유전상수는 10 kHz에서 3.37이며, 파장 1300 nm에서, 굴절률은 $n_{TE} 및 n_{TM}$ 모두 1.631로같았으며, 전기광학계수는 4.6 ~ 9.2 pm/V이였다. 폴링한 후 $180^{\circ}C$에서 1시간 동안 유지시킨 시편의 전기광학계수의 값은 감소되지 않 았으며, 장기적인 관점에서 $90^{\circ}C$에서 500 시간 동안 유지시킨 시편의 전기광학계수도 변함이 없었다.

• 한국주거학회논문집
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• 제26권6호
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• pp.17-25
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• 2015

Since 1997, Dr. Shin-ya Nishimura has been developing an actual town planning project named the "Gangi Project". Students, inhabitants and local professionals walk around Omotemachi, examine the characteristics of the environment and the inhabitants' way of life, discuss plans and designs for traditional wooden arcades called locally "gangi". Students and inhabitants build the gangi together every year. The purpose of this study is to clarify how an experimental project aiming to preserve a living environment obtains sustainability as an actual town planning exercise. The research hypothesizes that sustainable town planning should include strategies for financial autonomy, active participation of inhabitants, supports from local professionals, an acceptance of changing environments, and responsible construction. The project has been carried out as a part of actual town planning, and continues to create a daily living environment based on the recent economical and industrial situation of the town. By focusing on the influences of the project on the town and inhabitants, the study has revealed the possibility of an actual town planning with small budget, and importance of a collaborative relationship with various participants in order to foster a sense of responsibility regarding the construction. The project also highlights the implication that sustainable town planning creates not only a participatory system but also a collaborative one in which participants take responsibility for the issues involved in the construction process.

• 대한간호학회지
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• 제18권2호
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• pp.118-127
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• 1988

This descriptive-correlational study was undertaken in order to examine if there was relationship between health locus of control and health behavior of 122 residents in Choong Nam Province. The sampling method was non-probability, conventent sampling technique. Questionnaire survey was conducted from March 2 to March 11, 1988. Each participant completed the Multidimensional Health Locus of control(MHLC) scale (Wallsten & Wallston, 1978) and Health Behavior scale (developed by Dr. cho) The collected data were analyzed using Peason Correlation coefficient, t-test and Analusis of Variance. The results were as follows : 1. Hypothesis 1, stating that the higer the score of internal health locus of control, the higher the Score of level of actual implementation of health behavior was supported(r＝.1344, p＜.05). 2. Hypothesis 2, stating that the higher the score of chance health locus of control, the lower the score of level of actual implementation of health behavior was not supported (r＝-.1344, p＞.05). 3. Hypothesis 3, stating that the higher the score of internal health locus of control, the higher the score of the level of perceived importance of health behavior was supported (r＝.3373, p＜.001). 4. Hypothesis 4, stating that the higher the score of chance health locus of control, the lower the score of level of perceived importance of health behavior was not supported (r＝-.0810, p＞.05). 5. The mean score of internal was 23.36, powerful others was 19.04 and chance 15.36 out of maximum range of 6-30 respectively. The mean score of level of actual implementation of health behavior was 112.84 and level of perceived importance of health behavior 143.60 our of maximum range of 32-160 respectively. 6. The variances which were related with the level of actual implementation of health behavior, were education level, occupation, economic status, referred method of primary health, management and resicent's place. And the variance which were related with the level of perceived importance of health behavior were sex, economic status and occupation.

• 한국융합학회논문지
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• 제9권6호
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• pp.261-269
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• 2018

본 연구는 치위생과 학생들의 윤리성향, 자아존중감 및 임상실습 만족도가 전공만족도에 미치는 영향을 분석하였다. 경남과 울산 소재 3개 대학의 치위생과 3학년 학생 381명을 대상으로 조사연구하였다. 자아존중감은 학과 선택시기가 '고등학교 3학년 이전', 구강건강이 '건강하다', 성격은 '외향적', 가정 분위기는 '화목하다'에서 높았다. 임상실습 만족도는 '치과 아르바이트 경험'이 있다에서 높았고, 전공만족도는 학과 선택시기와 구강건강상태에서 유의한 차이가 있었다(p<0.05). 전공만족도에 영향을 미치는 요인은 자아존중감(${\beta}=.165$, p=.000)과 임상실습만족도(${\beta}=.630$, p=.000)이었다. 따라서 본 연구를 통해 치위생과 학생의 윤리의식 수준과 자아존중감, 임상실습만족도를 향상시킬 수 있는 교육과정 개발의 필요성을 확인하였다.

• 한국방사선학회논문지
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• 제6권2호
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• pp.121-127
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• 2012

일부지역의 전체 유방촬영장치는 205대가 설치 사용되고 있었으며 종합병원에는 36대, 병원 53대, 의원은 116대가 사용되고 있었다. 즉, 의원의 비중이 전체의 50%를 차지하고 있음을 알 수가 있었다. 영상획득방법 별에서는 필름 스크린(film screen)이 131대, 컴퓨터 방사선촬영장치(computed radipgraphy)가 67대, 디지털 방사선촬영장치(digital radiography)가 7대 순으로 나타났다. 현재까지는 주로 필름 스크린 시스템이 이용되고 있었다. target/filter의 재료는 대부분 Mo/Mo이 사용되었으며(66%), 그 다음으로는 Mo/Rh이 사용되고 있었다(25%). 초점의 크기는 소초점용은 0.1 mm, 대초점으로는 0.3 mm를 주로 사용하고 있었다.

• Asian Pacific Journal of Cancer Prevention
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• 제14권7호
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• pp.4365-4368
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• 2013

Background: Bronchioloalveolar carcinoma (BAC) is considered a subtype of adenocarcinoma of the lung. Recently BAC has been variously termed adenocarcinoma in situ, minimally invasive adenocarcinoma, lepidic predominant invasive adenocarcinoma, and invasive mucinous adenocarcinoma. The aim of the study was to analyze and detect prognostic factors of patients with BAC over a 7-year period. Materials and Methods: This retrospective single-center study included 44 patients with BAC. The impact on survival of fifteen variables (gender, age, smoking status, cough, dyspnea, hemoptysis, fever, chest pain, sputum, metastasis number, Karnofsky performance status, pT, pN, TNM stage, cytotoxic chemoterapy) were assessed. Results: Median age was 55 years (38-83). Most patients were male (63.6%) and stage IV (59.1%). Twenty-one patients (47.7%) received cytotoxic chemotherapy (platinum-based regimens) for metastatic disease. Objective response rate was 33.3% (4 partial, 3 complete responses). Stable disease was observed in nine in patients (42.8%). Disease progression was noted in 5 (23.8%). The median OS for all patients was 12 months (95%CI, 2.08-22.9 months). Independent predictors for overall survival were: Karnofsky performance status (HR:3.30, p 0.009), pN (HR:3.81, p 0.018), TNM stage (HR:6.49, p 0.012) and hemoptysis (HR:2.31, p 0.046). Conclusions: Karnofsky performance status, pN, TNM stage and hemoptysis appear to have significant impact on predicting patient survival in cases of BAC.

• 지역사회간호학회지
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• 제15권1호
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• pp.110-121
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• 2004

Purpose: This study was performed to identify factors associated with drinking behavior using Transtheoretical Model in workers. Method: The study method was a survey of 216 marine shipping metal workers in Koje city from November 11, 2002 to November 30, 2002. Result: The subjects were divided in four stages of drinking behavior: 38.9% in pre contemplation stage, 38.6% in contemplation stage, 17.6% in preparation stage and 7.9% in action & maintenance stage. The amount of drinking was significantly decreased as the workers progressed through each stage. Helping relationships(HR) and Self reevaluation(SR) were identified as the main processes of change in all stages. Self liberation(SEL), Counter conditioning(CC), Helping relationships(HR), Self reevaluation(SR), Dramatic relief (DR) and Social liberation(SL) were used higher than average. The self efficacy score increased as the workers progressed through each stage, but not significantly. The Pros score of decisional balance was the highest in the pre contemplation stage and decreased as the workers progressed through each stage. but not significantly. The Cons score of decisional balance was the highest in the preparation stage, but not significantly in as the workers progressed through each stage. Conclusion: This study can provide the basis of a staged matching alcohol reducing program using TTM for more effective and useful intervention.

• Asian Pacific Journal of Cancer Prevention
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• 제16권12호
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• pp.5053-5058
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• 2015

Background: Cervical cancer is one of the commonest cancers among women all over the world. The association of cervical cancer with human papilloma virus (HPV) is well established. Knowledge about the causal relationship between HPV and cervical cancer is important to make appropriate, evidence-based health care choices. In this context we conducted a community based study among women about the knowledge, attitude and practice about HPV infections and their health effects. Materials and Methods: A cross sectional interview based house to house survey was conducted with a validated data collection tool covering sociodemographic factors, knowledge, attitude and practice about HPV and its health effects, among 1020 women from a rural village, Perdoor, in Udupi district, Karnataka, India in 2013-14. Results: The mean age of participants was 38.9 years (SD=12.6). Study participants showed a high literacy rate (85.7%). Only 2.4% of sexually exposed women had undergone Pap smear testing. Partners of 4.4%women had undergone circumcision and they belonged to the Muslim community. Male condom usage was reported by 26 women (2.6%). However, none of the participants had heard of HPV and its health effects. Conclusions: This community based study found complete ignorance about HPV among rural South Indian women in spite of a high literacy level.