• Journal of Veterinary Clinics
• /
• v.9 no.1
• /
• pp.301-309
• /
• 1992

The present study was carried out to compare xylazine(2.2mg/kg, IV), xylazine/acepromazine(1.1mg/kg. IV : 0.2mg/kg, IV) and xylazine/diazepam(1.1mg/kg, IV :1.0mg/kg, IV) anesthesia, to determine useful method out of three kinds of anesthesia and tr evaluate this selected method at hypovolemic state. In xylazine, kylazine/acepromazine and kylazine/diazepam anesthesia, the heart rate was increases after administration of atropine until 10minutes after administration of anesthetics and then decreased gradually in all types of anesthesia. The respiratory rate was decreased after administration of anesthetics in all types of anesthesia. The body temperature was rarely changed in xyiazine/acepromazine and xylazine/diazepam anesthesia, but decreased continuously in xylazine anesthesia. In xylazine and kylazine/acepromazine anesthesia the pedal and corneal reflex were not disappeared completely, but reactions to pin pricking were disappeared. In xylazine/diazepam anesthesia their reflex and reactions were disappeared together. The time from head-up to standing was shortest(32.00min) in kylazine/diazepam anesthesia in comparision with xylazine and kylazine/acepromazine anesthesia. In xylazine/diazepam anesthesia, the heart rates in hypovolemic dogs were decreased soon after administration of anesthetics but recovered immediately. The changes in systolic and diastolic blood pressure in hypovolemic dogs revealed similar trends to their changes in normal dogs after administration of anesthetics. It is considered that rylazine/diazepam anesthesia is one of the useful anesthetic methods in healthy dogs and also in hypovolemic dogs.

• Korean Journal of Veterinary Research
• /
• v.32 no.3
• /
• pp.407-412
• /
• 1992

In order to obtain basic data concerning the treatment of canine demodicosis, 8 Doberman Pinschers were infected with Demodex canis. The clinical signs, were examined after infection, and their hematological and blood chemical values were determined, along with four non-infected control dogs of same breed. The number of white blood cells, especially the number of band neutrophils was significantly higher(p<0.01) in the infected than in the non-infected control dogs. This result indicated that the first episode of secondary infection should be treated with an appropriate antibiotics based on the culture and sensitivity test. The red blood cell counts, packed cell volume, hemoglobin contents, and serum albumin levels were significantly lower (p<0.01~0.001) in the infected than in the non-infected control dogs. These results suggested that the infected dogs had an anemia due to malnutrition. Thus, the infected dogs should be on a well balanced, high protein diet.

• KIEAE Journal
• /
• v.5 no.1
• /
• pp.19-25
• /
• 2005

Rapid urbanization and social development have brought about changes in family structure. In urbanized areas, recently the number of dogs that are a majority of companion animals has increased significantly in Korea. Consequently, a lot of friction between the general public who are not fond of dogs and dog owners in public places such as parks has been happening. A lot of countries that are taking a lead role in animal welfare have built dog parks that the general public and dogs can enjoy together. This research starts with the realization that the concept of 'dog park' needs to be introduced in Korea as more and more Koreans own dogs and other pets. This research aims to provide guidance for dog park planning by drawing planning items and analyzing the needs of each item. Total 56 planning items including dog zone, dog playground, and dog training facility, are drawn in this research. There are differences in the needs according to sex, age and the amount of time they spent with their dogs, however overall there is the highest needs in separated area for dogs in parks.

• Journal of Veterinary Clinics
• /
• v.16 no.2
• /
• pp.272-275
• /
• 1999

Generally, it is known that the composition of the cation of the dog's RBCs is high in potassium(K) and low in sodium(Na). However, it is reported that certain kinds of dogs have HK, HG phenotype which contains a large amount of reduced glutathione(GSH) by the effect of Na-K pump on the cell membrane of RBC with high concentration of K and low concentration of Na. Although this HK phenotype is not regarded as a disease, it is supposed to be an important assignment to examine the distribution and the occurrence rate of the dogs that contain HK cell in their RBCs for the proper clinical treatments as these HK dogs are very sensitive to aromatic disul-fide or onions and have a tendency to cause hemolysis. Accordingly, present study was performed to measure the concentration of K, Na and GSH in the RBCs of Jindo dogs and that of Dosa dogs at the same time.

• Journal of Veterinary Clinics
• /
• v.21 no.3
• /
• pp.276-279
• /
• 2004

Ninety-nine dogs diagnosed as tracheal collapse were reviewed for 2002-2003 year at Veterinary Medical Teaching Hospital, Seoul National University with clinical records and radiographs. Dogs were ranged in age from 1 to 15 years old (average 8.23 years old) and in weight from 1.2kg to 10.3kg (average 3.3kg). The population included 58 females (6 spayed) and 41 males (8 castrated). It is highly predominant in Yorkshire terrier (64, 64.6%) followed by Pomeranian (10, 10.1 %), Poodle and Chihuahua (8, 8.1%), Maltese (4, 4.0%), mixed breed (3, 3.0%), Cocker Spaniel and Pug (1, 1.0%). The incident rate of female dogs (59%) exhibited relatively higher than that of male dogs (41%). The most prevalent occurrence location was thoracic inlet (60%) of all and carina region (15%), intrathoracic trachea (14%) and cervical trachea (11 %) showed similar rate. Conclusively, tracheal collapse was observed in completely matured or old small breed dogs, largely Yorkshire terrier, on thoracic inlet primarily regardless of gender. These tendencies were apparently similar to previous reports.

• Journal of Veterinary Clinics
• /
• v.35 no.2
• /
• pp.35-38
• /
• 2018

Recently assessment of suppression of tumorigenicity 2 (ST2) level has become a useful cardiac biomarker in human medicine. This study compared serum ST2 levels and N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels between healthy dogs and dogs with chronic mitral valve disease. Twenty client-owned dogs were investigated. Dogs were divided into normal, asymptomatic, and symptomatic groups. Serum samples were used to measure levels of NT-proBNP and ST2. Samples for NT-proBNP were sent to IDEXX laboratory for analysis while ST2 levels were measured by using a canine interleukin 33 receptor ELISA kit. There was a significant difference in NT-proBNP levels between asymptomatic and symptomatic groups (P < 0.01), and between normal and symptomatic groups (P < 0.01). In contrast, ST2 levels were not relatively different between asymptomatic and symptomatic groups (P > 0.05). There was no significant difference was observed among all groups in ST2 study. The usefulness of measuring NT-proBNP level as a cardiac biomarker in dogs with chronic mitral valve disease was confirmed, but usefulness of the ST2 level was not observed. Further investigations are needed to evaluate the potential usefulness of ST2 level as a cardiac biomarker in canines.

• Toxicological Research
• /
• v.18 no.3
• /
• pp.241-248
• /
• 2002

The present study was conducted to investigate the potential subacute toxicity of CJ-10882 by a 4-week repeated oral dose in dogs. The test article was administered once dally by gavage to dogs at dose levels of 0, 2, 10, and 50 mg/kg/day for 4 weeks. During the test period, clinical signs, mortality, body weights, food consumption, ophthalmoscopy, urinalysis, hematology, serum biochemistry, gross finding, organ weight, and histopathology were evaluated. Several clinical sign were observed in treated dogs at 50 mg/kg, including salivation and vomiting. Increase in the serum level of ALT and albumin observed in the female 50 mg/kg group was considered as a toxic effect related to the test article since the histopathological change in Liver was accompanied. There were no treatment-related effects on mortality, food and water consumption, ophthalmoscopy, urinalysis, hematology, serum biochemistry, necropsy findings and organ weights in any treatment group. Based on these results, target organ was not observed and the no-observed-adverse-effect level (NOAEL) was 10 mg/kg/day and the absolute toxic dose was 50 mg/kg for both male and female dogs.

• Korean Journal of Veterinary Service
• /
• v.17 no.3
• /
• pp.174-180
• /
• 1994

The disease syndrome characterized by the acute vomiting and diarrhea with high mortality had been greatly epidemic in Kyungbuk West Area since March 1990 and it was followed serologically for the classification of the agent. The agent present in feces of dogs associated with this syndrome had characteristic feature in agglutinating pig red blood cells that was specifically inhibited by anti-CPV reference dog serum. This also showed the serological identity with the reference CPV antigen in Hemagglutinating inhibition test. The result obtained were summarized as follows : 1. During 5 years(March. 1990∼September. 1994), 1,470 dogs were investigated on the actual condition of CPV infections. The Infection rate of CPV from dogs was 62.5% and mortality rate was 59.8%. 2. Among 24 fecal samples collected from the dogs with enteric disease, all showed the hemagglutinating activity to porcine erythrocyte ranging from 40 to 5,120 of HA titers. 3. Among 12 sera samples collected from the dogs with enteric disease, all showed the serological identity with the reference CPV antigen from 5 to 5,120 of HI titers. 4. Bacteriologic examination of fecal specimens resulted in the isolation of pathogeric bacteria such as Staphylococcus sp, Streptococcus sp, Escherichia coli and Bacillus. Cultures for salmonella sp and Clostridium remaind negative. 5. The prevalence and identification of internal parasites were determined by fecal examination using the floatation methods. From 20 fecal samples 12(60.0%) were isolated and their species were Toxacara canis, Toxascaris leonina, and coccidium.

• Korean Journal of Veterinary Service
• /
• v.30 no.1
• /
• pp.155-164
• /
• 2007

This study was conducted to investigate the prevalence of canine heartworm infections, canine brucellosis and hematologic values from 153 free roaming dogs in the area of Gwangju city from March to November 2006. Nineteen (12.4%) of 153 samples tested with modified Knott's technique showed positive reaction for microfilariae. Polymerase chain reaction using specific primers for D immitis amplified the expected product from all samples of 19 microfilaremic canine blood samples as determined by the modified Knott's test for microfilariae. The seasonal infection rates of microfilariae were higher in the spring season (10/19, 52.6%) than in the other seasons. The major hematological findings in microfilaremic dogs were mild leukocytosis and mild monocytosis. A total of 100 dogs randomly selected from 153 free roaming dogs were negative for canine brucellosis by serological test using immunochromatographic antibody test kit.

• Korean Journal of Veterinary Research
• /
• v.55 no.4
• /
• pp.221-225
• /
• 2015

This study evaluated the effects of alfaxalone (3 mg/kg, intravenously) on echocardiographic examination in healthy dogs using echocardiography. Six adult Beagle dogs were used for this study. Left ventricular dimensions with systolic indexes, trans-blood flow at all cardiac valvular annulus and trans-mitral tissue Doppler values were measured from routine transthoracic echocardiography. Although the changes were not statistically significant, heart rate, left ventricular end-systolic diameter, left ventricular end-diastolic diameter, peak velocities of tricuspid A-wave and transpulmonic flow were increased after alfaxalone induction, while systolic blood pressure, fractional shortening, left ventricular ejection fraction, peak velocities of mitral E-wave, mitral A wave, tricuspid E-wave, transaortic flow and medial e'-, a'- and s'-peaks decreased after alfaxalone induction. No dogs showed hypoxemia during sedation, regardless of intubation and oxygen supply. Although alfaxalone showed mild cardiovascular depression, this protocol could be a good alternative sedative protocol for echocardiographic examination in healthy dogs because the cardiovascular depression was statistically and clinically insignificant. However, further studies in dogs with heart diseases should be conducted to confirm these findings after alfaxalone induction.