• Spatial Information Research
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• 제19권5호
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• pp.37-46
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• 2011

봄 가뭄탐지를 위한 위성영상 활용을 위해 중 저해상 위성영상인 Landsat TM(Thematic Mapper) 영상을 이용하여 기존의 봄철 가뭄 해석에 많이 사용되어온 정규식생지수(NDVI: Normalized Difference Vegetation Index)이외에 MSI(Moisture Stress Index), MidIR Index, II (Infrared Index) 지수들의 가뭄분석 활용가능성을 알아보고자 하였다. 이를 위해 경상북도 영천시를 대상으로 무강수일수에 따른 영상을 선정하여 DN(Digital Number)값의 특성 및 상관성을 분석하고 이와 더불어 가뭄지수와의 비교 분석을 실시하였다. 그 결과 NDVI와 MSI 및 II 지수는 높은 상관관계를 보였으나, MidIR은 낮은 상관관계를 보였으며, 가뭄지수와의 분석에서도 MSI 및 II 지수는 강한 상관관계를 보여주었다. 따라서 MSI와 II 지수를 이용한 가뭄연구를 통해 정보의 다양성 및 정확도를 높일 수 있을 것으로 판단된다.

• 대한화학회지
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• 제48권1호
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• pp.17-27
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• 2004

SPME-GC/MS법을 사용하여 내분비계 교란물질로 추정되는 플라스틱 가소제류를 동시에 분석할 수 있는 방법을 고안하였다. 본 연구에서 사용한 플라스틱 가소제는 dimethyl phthalate(DMP), diethyl phthalate(DEP), dibutyl phthalate(DBP), benzylbutyl phthalate(BBP), diethylhexyl phthalate(DEHP), di-n-octyl phthalate(DnOP)이었다. 표준 시료에 대한 분석결과에서 검출한계(LOD)는 0.163~0.299 ng/ml, 상대표준편차는(%RSD)는 5.85~15.80이었다. 본 방법을 사용하여 한강, 금강, 낙동강 및 섬진강에서 채취한 시료를 분석한 결과, DBP와 DEHP 만이 4대강 모두에서 미량 검출되었으며, DBP와 DEHP의 농도는 각각 0.192~1.270 ng/ml 및 0.077~1.102 ng/ml 범위를 보였다.

• Biomolecules & Therapeutics
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• 제24권5호
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• pp.536-542
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• 2016

Shuangdan oral liquid (SDO) containing radix Salviae miltiorrhizae (Chinese name Danshen) and cortex moutan (Chinese name Mudanpi) is a traditional Chinese medicine using for treating vascular diseases. Danshensu (DSS) is a main effective monomer composition derived from radix Salviae miltiorrhizae and paeonol (Pae) from cortex moutan. Although the two herbs are widely used in traditional Chinese medicine, the pharmacological functions of their active compositions were not reported. Therefore, the research of DSS and Pae in mechanisms and pharmacodynamics interaction can provide scientific evidence to support clinical application. The diabetic nephropathy (DN) rats which were induced by streptozotocin (STZ) were treated with SDO, DSS, Pae, and DSS+Pae for eight weeks. The positive effects on DN animal models were investigated by detection of physiological and biochemical indexes and oxidative stress markers, within five treatments: SDO, DSS, Pae, DSS+Pae and insulin group. Compared with the model group, the DSS+Pae group improved the renal function, blood lipid metabolism and blood viscosity, increased the vitality of T-SOD or T-AOC and decreased the level of MDA or NO after the treatment. The study was successfully showed that the DSS+Pae group could delay the process of DN, especially in the renal injury part of histopathology changes. Our results suggest that the co-administration of DSS and Pae significantly may play a protective role in DN rats through decreasing the oxidative stress and improving the blood lipid metabolism mechanisms.

• 정보보호학회논문지
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• 제28권5호
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• pp.1141-1151
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• 2018

APT(Advanced Persistent Threat) 공격에서 감염 호스트와 C&C(Command and Control) 서버 간 통신은 공격 대상의 내부로 침입하기 위한 핵심단계이다. 공격자는 C&C 서버를 통해 다수의 감염 호스트를 제어하고, 침입 및 공격 행위를 지시하는데, 이 단계에서 C&C 서버가 노출되면 공격은 실패할 수 있다. 따라서 최근의 경우 DGA(Domain Generation Algorithm)를 통해 C&C 서버의 DNS를 짧은 시간 간격으로 교체하여 탐지를 어렵게 하고 있다. 특히 하루에도 500만개 이상 새로 등록되는 DNS 전부를 검증하고 탐지하는 것은 매우 어렵다. 이러한 문제점을 해결하기 위해 본 논문에서는 정상 DNS와 DGA를 통해 생성된 DNS(DGA-DNS)의 형태적 유사도(similarity) 분석을 이용한 DGA-DNS 탐지와 이를 통해 APT 공격 징후로 판단하는 모델을 제시하고 유효성을 검증한다.

• IEIE Transactions on Smart Processing and Computing
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• 제4권4호
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• pp.195-201
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• 2015

For median filtering (MF) detection in altered digital images, this paper presents a new feature vector that is formed from autoregressive (AR) coefficients via an AR model of the gradients between the neighboring row and column lines in an image. Subsequently, the defined 10-D feature vector is trained in a support vector machine (SVM) for MF detection among forged images. The MF classification is compared to the median filter residual (MFR) scheme that had the same 10-D feature vector. In the experiment, three kinds of test items are area under receiver operating characteristic (ROC) curve (AUC), classification ratio, and minimal average decision error. The performance is excellent for unaltered (ORI) or once-altered images, such as $3{\times}3$ average filtering (AVE3), QF=90 JPEG (JPG90), 90% down, and 110% up to scale (DN0.9 and Up1.1) images, versus $3{\times}3$ and $5{\times}5$ median filtering (MF3 and MF5, respectively) and MF3 and MF5 composite images (MF35). When the forged image was post-altered with AVE3, DN0.9, UP1.1 and JPG70 after MF3, MF5 and MF35, the performance of the proposed scheme is lower than the MFR scheme. In particular, the feature vector in this paper has a superior classification ratio compared to AVE3. However, in the measured performances with unaltered, once-altered and post-altered images versus MF3, MF5 and MF35, the resultant AUC by 'sensitivity' (TP: true positive rate) and '1-specificity' (FN: false negative rate) is achieved closer to 1. Thus, it is confirmed that the grade evaluation of the proposed scheme can be rated as 'Excellent (A)'.

• 한국미생물·생명공학회지
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• 제16권5호
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• pp.363-368
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• 1988

반합성 베타 락탐 항생물질의 가수분해 및 합성을 촉매하는 효소인 $\alpha$-acylamino-$\beta$-lactam acylhydrolase(ALAH)의 유전자를 Acetobacfer turbidans로부터 클론화하기 위한 연구를 수행하였다. 우선 순수 분리 정제된 효소에 대한 항혈청 (폴리클론 항체)을 제조한 다음 이를 probe로 하여 면역화학적 방법으로 유전자의 선별을 시도하였다. 이러한 용도로 개발된 운반체인 λ gtll에다 A. turbidans의 유전자 단편들을 삽입하여 genomic library를 제조한 후 이 library에서 유전자를 선별한 결과 두개의 positive clone을 얻을 수 있었다. 그러나. 이 두 clone들은 면역화학적으로 서로 다른 반응을 나타내었는데, 그 중 하나는 효소의 항혈청과는 잘 결합하나 융합되어진 베타 갈락토시다아제에 대한 항체와는 잘 결합하지 못하였고(λ gtll dn1), 또 다른 clone 은 이와 반대의 양상을 보여주었다(λ gtll dn2). 더구나 이들 clone을 여러 제한효소들로 분석해본 결과, 유전자가 삽입된 부분인 Eco RI 부위중 하나가 없어진 것을 알 수 있었다. 따라서 A. turbidans의 효소에 대한 유전자가 λ gtll에 클론화 되었으나 이 유전자와 베타 갈락토시다아제의 유전자(lacZ)간에 염기배열상 동위성이 있은 부위가 존재하여 재조합된 λ gtll 파지의 복제과정에서 삭제되어진 것으로 간주되어진다.

• Environmental Analysis Health and Toxicology
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• 제26권
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• pp.8.1-8.9
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• 2011

Objectives: This study assessed the health risks for children exposed to phthalate through several pathways including house dust, surface wipes and hand wipes in child facilities and indoor playgrounds. Methods: The indoor samples were collected from various children's facilities (40 playrooms, 42 daycare centers, 44 kindergartens, and 42 indoor-playgrounds) in both summer (Jul-Sep, 2007) and winter (Jan-Feb, 2008). Hazard index (HI) was estimated for the non-carcinogens and the examined phthalates were diethylhexyl phthalate (DEHP), diethyl phthalate (DEP), dibutyl-n-butyl phthalate (DnBP), and butylbenzyl phthalate (BBzP). The present study examined these four kinds of samples, i.e., indoor dust, surface wipes of product and hand wipes. Results: Among the phthalates, the detection rates of DEHP were 98% in dust samples, 100% in surface wipe samples, and 95% in hand wipe samples. In this study, phthalate levels obtained from floor dust, product surface and children's hand wipe samples were similar to or slightly less compared to previous studies. The $50^{th}$ and $95^{th}$ percentile value of child-sensitive materials did not exceed 1 (HI) for all subjects in all facilities. Conclusions: For DEHP, DnBP and BBzP their detection rates through multi-routes were high and their risk based on health risk assessment was also observed to be acceptable. This study suggested that ingestion and dermal exposure could be the most important pathway of phthalates besides digestion through food.

• Nuclear Engineering and Technology
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• 제55권10호
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• pp.3648-3658
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• 2023

The early localization of a fuel subassembly with a failed (wet rupture) fuel pin is very important in reactors to limit the associated radiological and operational consequences. This requires a fast and reliable system for failure detection and their localization in the core. In the Prototype Fast Breeder Reactor, the system specially designed for this purpose is Failed Fuel Location Modules (FFLM) housed in the control plug region. It identifies a failed sub-assembly by detecting the presence of delayed neutrons in the sodium from a failed sub-assembly. During the commissioning phase of PFBR, it is mandatory to demonstrate the FFLM effectiveness. The paper highlights the engineering and physics design aspects of FFLM and the integrated simulation towards its function demonstration with a source assembly containing a perforated metallic fuel pin. This test pin mimics a MOX pin of 1 cm² of geometrical defect area. At 10% power and 20% sodium flow rate, the counts rate in the BCCs of FFLM system range from 75 cps to 145 cps depending upon the position of DN source assembly. The model developed for the counts simulation is applicable to both metal and MOX pins with proper values of k-factor and escape coefficient.

• Journal of the Korean Society for Industrial and Applied Mathematics
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• 제25권4호
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• pp.327-336
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• 2021

In this paper, we will introduce the image processing methods for the remote pupillary light reflex measurement using the video taken by a general smartphone camera without a special device such as an infrared camera. We propose an algorithm for estimate the size of the pupil that changes with light using image data analysis without a learning process. In addition, we will introduce the results of visualizing the change in the pupil size by removing noise from the recorded data of the pupil size measured for each frame of the video. We expect that this study will contribute to the construction of an objective indicator for remote pupillary light reflex measurement in the situation where non-face-to-face communication has become common due to COVID-19 and the demand for remote diagnosis is increasing.

• The Plant Pathology Journal
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• 제20권4호
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• pp.302-307
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• 2004

Three pairs of specific primers were developed for rapid and precise RT-PCR detection of three seed-transmissible viruses, namely Peanut clump virus (PCV, Pecluvirus), White clover mosaic virus (WCIMV, Potexvirus) and Carrot red leaf virus (CaRLV, Luteovirus). Each primer set was found in conserved region through multiple sequence alignment in the DNAMAN. Total nucleic acids extracted from PCV-, WCMV-, and CaRLV-infected seeds and healthy plants were used for RT-PCR detection using each virus-specific primer, Sizes of PCV, WCIMV, and CaRLV PCR products were 617bp (PCV-uni5 and PCV-uni3 primers), 561bp (WCMV-CP5 and WCMV-CP3 primers), and 626bp (CL1-UP and CL2-DN primers); which corresponded to the target sizes. Nucleotides sequences of each amplified cDNA were confirmed which belonged to the original virus. This study suggests that these virus-specific primer sets can specifically amplify viral sequences in infected seeds. Thus, they can be used for specific detection of three viruses (PCV, WCMV and CaRLV) from imported seed samples for plant quarantine service.