• 제목/요약/키워드: DMPC

검색결과 37건 처리시간 0.021초

유기박막의 전계자격에 의한 전기 특성에 관한 연구 (A study on the Electrical Properties by Electric Field Stimulus of Organic Thin Films)

  • 조수영;전동규;송진원;김해진;이우선;최영일;이경섭
    • 한국전기전자재료학회:학술대회논문집
    • /
    • 한국전기전자재료학회 1999년도 춘계학술대회 논문집
    • /
    • pp.49-52
    • /
    • 1999
  • We studied on the ultra thin DMPC by Langmuir-Blodgett(LB) method. The $\pi$ -A isotherm of the DMPC was measured at the air-water interface varying with the compressing speed and amounts of solutions for spreading. DMPC molecules have one phosphatidylcholine head group and two long alky groups with carbonyl group. Displacement currents generated during the compression of monolayers of DMPC on the surface of water were investigated. The molecular arrangement of deposited films were evaluated by measuring the absorption with the UVspectrometer. And we made structures of metal(Au)/DMPC/Metal(Au) and examined electron through DMPC LB films by means of current-voltage(I-V) measurement .

  • PDF

Flip-Flop of Phospholipids in DMPC/POPC Mixed Vesicles

  • Kim, Min Ki;Kim, Chul
    • 대한화학회지
    • /
    • 제64권3호
    • /
    • pp.145-152
    • /
    • 2020
  • Flip-flop rate constants were measured by dithionite assay of NBD-PE fluorescence in DMPC/POPC vesicles made of various DMPC/POPC ratios. The activation energy, enthalpy, entropy, and free energy were determined based on the transition state theory. We found that the activation energy, enthalpy, and entropy increased as the amount of POPC increased, but the activation free energy was almost constant. These experimental results and other similar studies allow us to propose that the POPC molecules included in DMPC vesicles affect the flip-flop motion of NBD-PE in DMPC/POPC vesicles via increasing the packing order of the ground state of the bilayer of the vesicles. The increase in the packing order in the ground state seems to be a result of the effect of the overall molecular shape of POPC with a monounsaturated tail group, rather than the effect of the longer tail group.

DMPC 단분자막의 변위전류 특성 연구 (A Study on Displacement Current DMPC Monolayer)

  • 최용성;조장훈;송진원;이경섭
    • 한국전기전자재료학회:학술대회논문집
    • /
    • 한국전기전자재료학회 2006년도 추계학술대회 논문집 Vol.19
    • /
    • pp.168-169
    • /
    • 2006
  • The physical properties of DMPC monolayer were made for dielectric relaxation phenomena by the detection of the surface pressures and displacements current. The phospolipid monolayer of dielectric relaxation takes a little time and depend on the molecular area.

  • PDF

포화지방산과 인지질(DMPC)혼합 Langmuir-Blodgett막의 전기화학적 특성에 관한 연구 (A Study on the Electrochemical Properties of Langmuir-Blodgett Film Mixed with Saturated Fatty Acid and Phospholipid(DMPC))

  • 우성협;박근호
    • 한국응용과학기술학회지
    • /
    • 제31권3호
    • /
    • pp.359-366
    • /
    • 2014
  • 포화지방산과 인지질(DMPC)혼합 LB막에 대한 전기화학적 특성을 조사하였다. 포화지방산과 DMPC 혼합 단분자 LB막은 ITO glass에 Langmuir-Blodgett법을 사용하여 제막하였다. 전기화학적 특성은 $NaClO_4$ 용액에서 3 전극 시스템 (Ag/AgCl 기준전극, 백금선 카운터 전극 및 LB 필름이 코팅된 ITO 작업 전극)으로 순환전압전류법을 사용하여 측정하였다. 그 결과 포화지방산과 인지질(DMPC)의 LB막은 순환전압전류도표로부터 산화전류로 인한 비가역공정으로 나타났다. 포화지방산과 인지질(DMPC)혼합(몰비 1:1) LB막(C14, C16, C18, C20)에서 확산계수(D)는 0.05 N $NaClO_4$에서 각각 $1.2{\times}10^{-3}$, $2.1{\times}10^{-3}$, $1.4{\times}10^{-4}$$1.1{\times}10^{-3}cm^2/s$로 산출되었다.

DMPC 인지질 단분자막의 변위전류 특성 연구 (II) (A Study on Displacement Current Characteristics of DMPC Monolayer (II))

  • 송진원;이경섭;최용성
    • 전기학회논문지
    • /
    • 제56권2호
    • /
    • pp.343-348
    • /
    • 2007
  • The physical properties of DMPC monolayer were made for dielectric relaxation phenomena by the detection of the surface pressures and displacements current. Lipid thin films were deposited by accumulation and the current was measured after the electric bias across the manufactured MIM device. It is found that the phospolipid monolayer of dielectric relaxation takes a little time and depend on the molecular area. When electric bias is applied across the manufactured MIM device by the deposition condition of phospolipid mono-layer, it wasn't breakdown when the higher electric field to impress by increase of deposition layers.

유기지방산(DMPC)의 전기 특성에 관한 연구 (A Study on the Electrical Properties of Organic Fatty Acid(DMPC))

  • 송진원;구할본;김형곤;신석두;김영진;최영일;이경섭
    • 한국전기전자재료학회:학술대회논문집
    • /
    • 한국전기전자재료학회 1999년도 춘계학술대회 논문집
    • /
    • pp.45-48
    • /
    • 1999
  • Monolayers of lipids on a water surface have attracted much interest as models of biological membranes, but also as precursors of multilayer systems promising many technical applications. Until now, many methodologies have been developed in order to gain a better underst. DMPC molecules have one phosphatidylcholine head group and two long alkyl groups with carbonyl group. Displacement currents generated during the compression of monolayers of DMPC on the surface of water were investigated. As results, the displacement pick was generated when the area per molecule was about 190$\AA$$^2$in low pressure, and it was generated when the area per molecule about 190$\AA$$^2$ in for pressure, and it was generated when the area per molecule about 150 $\AA$$^2$ in high pressure. Also. for the study of photo device measured the absorption rate. the maxim value shown was 2800-2900nm.

  • PDF

Effect of Phase Transition Temperature of Phospholipid on the Stability of Retinol Incorporated into Liposomes

  • Lee, Kyung-Eun;Kim, Jin-Ju;Yuk, Hyun-Gyun;Jang, Ji-Young;Lee, Seung-Cheol
    • Preventive Nutrition and Food Science
    • /
    • 제8권3호
    • /
    • pp.235-238
    • /
    • 2003
  • We investigated the effect of the phase transition temperature (T$_{c}$) of phospholipid in liposomes on the stability of incorporated retinol. Two kinds of phospholipid which have different T$_{c}$, L- $\alpha$ -dimyristoyl phosphatidyl choline (DMPC, T$_{c}$=22$^{\circ}$C) and D,L- $\alpha$ -dipalmitoyl phosphatidyl choline (DPPC, T$_{c}$=42$^{\circ}$), were used to prepare liposomes. Liposome with retinol was prepared as multilamella vesicles (MLVs) by the dehydration/rehydration method. The incorporation efficiency of retinol into liposomes prepared from DMPC and DPPC were 99.89$\pm$0.08% and 99.97$\pm$0.03, respectively. The average size of liposomes from DPPC were greater than that of DMPC. Two kinds of liposomes in phosphate buffer (10 mM, pH 7.0) were stored at 15, 30, and 5$0^{\circ}C$, and stability of incorporated retinol was analyzed. The stability of retinol in DMPC liposome was decreased, whereas the stability in DPPC liposome was increased as temperature increased, although the overall protection effect of liposome on the incorporated retinol was greater in DMPC liposomes than in DPPC liposomes.posomes.

나노기술을 위한 DMPC 유기박막의 유전완화특성 (Dielectric Relaxation Properties of DMPC Organic Thin Films for Nanotechnology)

  • 최영일;조수영
    • 전자공학회논문지 IE
    • /
    • 제49권1호
    • /
    • pp.7-11
    • /
    • 2012
  • 본 논문에서는 인지질 단분자인 DMPC 유기초박막에 압력 자극을 이용하여 표면압과 변위전류의 검출에 따른 유전 완화현상에 대한 물리적 특성 평가를 하였다. 유기초박막에서 약간의 유전 완화 시간이 소요되었는데 이는 분자 영역에 의존한다는 사실을 알 수 있었다. 또한, 유기박막의 누적 조건에 의해 제작된 MIM 소자에 전압을 인가시, LB막의 누적층수가 증가 할수록 저항이 증가한다는 것을 알 수 있었는데 이는 유기초박막의 층수가 증가하여 전극간의 거리가 멀어질수록 더 높은 전계에서도 파괴되지 않는 절연특성이 나타남을 알 수 있었으며 나노단위의 유기초박막의 비교적 양호한 절연성을 확인, 제시 하였다.

유기초박막의 산화-환원 반응에 관한 연구 (A Study on the Oxidation-reduction Reaction of Organic Thin Films)

  • 박근호;송주영
    • 한국전기전자재료학회논문지
    • /
    • 제19권8호
    • /
    • pp.724-731
    • /
    • 2006
  • We investigated the electrochemical properties for Langmuir-Blodgett (LB) films mixed with 4-octyl-4'-(5-carboxylpentamethyleneoxy)azobenzene (denoted as 8A5H) and phospholipid(L-a-dimyristoylphosphatidylcholine, denoted as DMPC and L-a-dilauroylphosphayidylcholine, denoted as DLPC). The LB films of 8A5H, 8A5H-DMPC and 8A5H-DLPC mixture monolayers were deposited by using the LB method on the indium tin oxide(ITO) glass. The electrochemical properties measured by using cyclic voltammetry with a three-electrode system, an Ag/AgCl reference electrode, a platinum wire counter electrode and LB film-coated ITO working electrode at various concentrations(0.1, 0.5, and 1.0 mol/L) of $NaClO_4$ solution. A measuring range was reduced from initial potential to -1350 mV, continuously oxidized to 1650 mV and measured to the initial point. The scan rates were 50, 100, 150 and 200 mV/s, respectively. As a result, LB films of 8A5H and 8A5H-DLPC mixture monolayers appeared irreversible process caused by only the oxidation current from the cyclic voltammogram and LB films of 8A5H-DMPC monolayer mixture was found to be caused by a reversible oxidation-reduction process.

DMPC 인지질 단분자막의 변위전류 특성 (Displacement Current Characteristics of DMPC Lipid Monolayer)

  • 최용성;송진원;이경섭
    • 대한전기학회:학술대회논문집
    • /
    • 대한전기학회 2006년도 추계학술대회 논문집 전기물성,응용부문
    • /
    • pp.12-13
    • /
    • 2006
  • The physical properties of DMPC monolayer were made for dielectric relaxation phenomena by the detection of the surface pressures and displacements current. The current was measured after the electric bias across the manufactured MIM device. It is found that the phospolipid monolayer of dielectric relaxation takes a little time and depend on the molecular area. When electric bias is applied across the manufactured MIM device by the deposition condition of phospolipid mono-layer, it wasn't breakdown when the higher electric field to impress by increase of deposition layers.

  • PDF