• Journal of Food Hygiene and Safety
• /
• v.16 no.2
• /
• pp.125-132
• /
• 2001

The present study was conducted to investigate biological degradability of phosphamidon and profenfos. In the biodegradation test of two pesticides by the modified river die-away method from May 20 to July 29, 1999, the biodegradation rate was determined in Nakdong (A) and Kumho(B) River. The residual percentages of phosphamidon were 74.9%, 68.8% and 62.7% in control, A and B samples 7 days after applicaton, respectively. Biodegradation constants and half-lives of phosphamidon were 25.1%, 21.9% and 11.9% in control, A and B samples 7 days after application. Biodegradation constants and half-lives of profenofos were 0.0005 and 58.4 days in A, 0.0013 and 21.6 days in B, respectively. The biodegradation rates of phosphamidon and profenofos were higher in the Kumho River (B) than in the Nackdong River(A). The strains of microorganisms for the degradation of phosphamidon and profenofos were identified as Klebsiella pneumoniae, Aeromonas hydrophila and Acinetobacter calcoaceticus, all Gram-negative bacteria. In order to identify biodegradate products, the extracts of cultivates were analyzed by GC/MS. The mass spectra of biodegradate roducts of phosphamidon were at m/z 153 and 149, those of the profenofos were at m/z 208 and 240, respectively. It was suggested that the biodegradate metabolites of phosphamidon were O, O-dimethyl phosphate(DMP) and N, N-diethylchloroacetamide, those of profenofos were 4-bromo-2-chlorophenol and O-ethyl-S-propyl phosphate.

• Journal of Food Hygiene and Safety
• /
• v.14 no.4
• /
• pp.339-345
• /
• 1999

The present study was performed to investigate photodegradation rate constants and degradation products of dichlorvos and methidathion by the USEPA method. The two pesticides were very stable in sunlight for 16 days from September 2 to 18, 1998 and humic acid had no sensitizing effect on the photolysis of each pesticide in sunlight. The photolysis rate was fast-est for methidathion, followed by dichlorvos in the presence of UV irradiation. Photodegradation rate constant and half-life of dichlorvos were 0.0208 and 33.3 min, respectively. Photodegradation rate constant and half-life of methidathion were 0.6789 and 1.0min, respectively. The two pesticides were degraded completely in the presence of UV irradiation and UV irradiation with TiO$_2$in about 3 hours. Therefore, it is suggested that UV treatment will be effective for the degradation of pesticides in the process of drinking water purification. In case of dichlorvos and methidathion, UV irradiation with TiO$_2$was more effective for degradation than W irradiation. In order to identify photolysis products, the extracts of degradation products were analyzed by GC/ MS. The mass spectrum of photolysis products of dichlorvos was at m/z 153, those of the photolysis of methidathion were at m/z 198 and 214, respectively. Photolysis products of dichlorvos was Ο, Ο-dimethyl phosphate(DMP), those of methidathion were Ο, Ο-dimethyl phosphorothioate(DMTP) and Ο, Ο-dimethyl phosphorodithioate (DMDTP).

• The Journal of Korean Academy of Prosthodontics
• /
• v.58 no.1
• /
• pp.58-66
• /
• 2020

Implant-Assisted Removable Partial Dentures (IARPDs) treatment is being performed in a fully edentulous patient using implant surveyed prosthesis as an abutment. Implant-supported prosthesis as an abutment of IARPDs is classified into screw-retained and cement-retained type according to the retention type, and each has advantages and disadvantages. The EZ crown system (Samwon DMP, Yangsan, Korea) has a cylinder combined with abutment, and the nickel-titanium spring in this cylinder provides a constant force on the zirconia ball to obtain retention in EZ crown system. In this patient, the natural abutment teeth of the mandibular overdenture was hopeless. We planned implant assisted removable partial denture using anterior implant surveyed prosthesis considering functional and esthetical rehabilitation, cost and patient's needs. When fabricating IARPDs using implant as abutment, we could compensate for the shortcomings of existing implant-supported prosthesis retention type and made the design of removable partial denture easy due to using EZ crown system.

• Proceedings of the Korean Society for Information Management Conference
• /
• 2017.08a
• /
• pp.100-100
• /
• 2017

100년의 역사를 지닌 한국지질자원연구원(KIGAM)은 국내 유일의 지질자원 전문연구기관으로서 그간 생산한 조사 연구데이터는 우리나라 과학기술의 귀중한 역사적 학술적 가치가 큰 유산으로써 보존 가치가 매우 크다고 할 수 있다. 하지만 현재 KIGAM의 상황은 최종성과물 위주로 자료관리가 이루어지고 있으며, 조사 연구 과정에서 생산된 암석 토양 지하수샘플이나 조사 탐사장비를 통해 얻어지는 자료는 연구자 또는 연구실 팀에서 개별적으로 관리하고 있다. 이러한 자료관리체계는 자료의 공동 활용이 어렵고, 자료를 보유하고 있는 연구자의 퇴직이나, 조직개편으로 인한 팀 실의 분리 과정에서 자료의 손실과 훼손 가능성이 높고, 누가 어디에 어떤 자료를 무슨 형태로 보관하고 있는지 찾기 어려워 자료의 재활용도가 떨어질 뿐만 아니라, 이로 인한 중복 조사 연구 가능성도 배제할 수 없다. KIGAM은 지질자원분야 국가데이터센터 구축을 목표로 연구과정에서 생산되는 연구데이터의 체계적인 관리와 공유, 활용체계 구축을 위해 2015년도에 기획사업을 통해 중장기 로드맵을 포함한 추진전략을 수립하였으며, 한국과학기술정보연구원(KISTI)의 DataNest를 기술이전받아 지질자원 연구데이터 리포지토리 시스템(GDR: Geoscience Data Repository)를 개발하였다. GDR 시스템 개발을 위해 연구데이터 분류코드를 작성하였으며, 2016년부터 데이터관리계획(DMP: Data Management Plan)을 주요사업 연구계획서 양식에 포함시켜 제출하도록 하였다. 과거 KIGAM은 연구데이터를 수집, 관리하기 위해 몇 차례에 걸쳐 시도를 했지만 실패한 경험을 가지고 있다. 실패 요인에는 (1) 관련 정책, 제도, 조직, 인력, 예산 등 데이터 관리 인프라 부재, (2) 연구사업에서 생산된 데이터는 개인소유라는 인식 및 공유 의식 부족, (3) 데이터 관리 활동은 귀찮은 것이고, 시간 낭비라는 인식, (4) 데이터 관리 공개 공유 활동에 대한 보상체계 부재 등을 꼽을 수 있다. 즉, 제도를 포함한 인프라 부족과 경영진과 구성원의 인식부족이 제일 큰 원인으로 판단된다. 성공적인 연구데이터 관리를 위해서는 지속적이고 꾸준한 투자가 이루어져야 하지만 경영진의 의지에 따라 사업이 중단되기도 한다. 이러한 과거의 실패 요인에 대한 해결 없이 지난 1년 6개월 정도의 GDR 운영은 지지부진하였다. 이러한 문제점을 해결하기 위해서는 국가차원의 제도적 뒷받침이 따라야 한다. 즉 국가 R&D 성과물 관리차원에서 연구데이터를 주요 성과물로 관리해야 할 것으로 판단된다. 연구사업계획서에 DMP를 포함시키고, 연구주제 및 분야별로 데이터센터(혹은 데이터 리포지토리)를 지정하고, 국가 R&D에서 생산되는 연구데이터를 의무적으로 제출하도록 하는 것이다. 또한 데이터센터의 안정적이고 지속적인 운영을 위해 연구사업비 항목에 데이터 관리비를 신설하여 데이터센터의 운영비로 사용하도록 하면 예산문제도 어느 정도 해결 될 수 있을 것으로 본다. 또한 데이터 제출 및 인용도에 따라 데이터 생산부서 혹은 생산자에게 평가점수를 부여하는 등 보상체계 마련을 위한 연구도 필요할 것으로 보인다. 국가 R&D 연구데이터의 수집, 관리, 공유, 활용을 제대로 성공시키려면 국가 R&D 최고정책결정자의 지속적인 관심과 지원이 필수적이다.

• Journal of Acupuncture Research
• /
• v.29 no.6
• /
• pp.57-71
• /
• 2012

Objectives : The purpose of this study is to find the effects of Sa-Am stomach tonifying acupuncture on radial pulse through the parameters difference. Methods : Forty healthy subjects participated in this study, acupuncture group and control group were divided. Radial pulse were measured using 3 dimensional pulse imaging system(DMP-3000). 19 parameters that significantly changed were selected after comparing between acupuncture group and control group. Then, 19 parameters were analyzed before, immediately after, 30 minutes after and 60 minutes after acupuncture in acupucture group. Results : 1. Heart rate, pulse period, T/T1, T2/T, T4/T, T5/T, T-T4, (T-T4)/T and T4/(T-T4) significantly changed after acupuncture. 2. H1 Amplitude, H2 Amplitude, H4 Amplitude and H5 Amplitude significantly changed after acupuncture. 3. Area of Pulse Wave, Systolic Pulse Area, Diastolic Pulse Area and Area of W significantly changed after acupuncture. 4. AIx/HR significantly changed after acupuncture. Conclusion : Stomach Tonifying Acupuncture exerts an influence on radial pulse parameters. Further radial pulse change study on various acupuncture treatment is required.

• Korean Journal of Acupuncture
• /
• v.28 no.2
• /
• pp.13-22
• /
• 2011

Objectives : The purpose of this study is to investigate the effect of food intake on radial pulse amplitude. Methods : Thirty one healthy male subjects participated in this study. Radial pulse was measured using 3 dimensional pulse imaging system (DMP-3000) before, right after, 40 minutes after, 80 minutes after and 120 minutes after food intake. Results : 1. The amplitude of h1 increased significantly right after food intake compared to 'before food intake' at all 6 measuring points. Later on, it decreased back as time passed, however, even 120 minutes later, it was still higher than 'before food intake' 2. Pulse energy, which is calculated from pulse waves acquired with five sensors, increased after food intake as well. Conclusions : Food intake exerts an influence on radial pulse amplitude, resulting in increase of h1 and pulse energy.

• International Journal of Oral Biology
• /
• v.42 no.2
• /
• pp.39-45
• /
• 2017

Metformin (1,1-dimethylbiguanide hydrochloride), derived from French lilac (Galega officinalis), is a first-line anti-diabetic drug prescribed for patients with type 2 diabetes. However, the role of metformin in odontoblastic cell differentiation is still unclear. This study therefore undertook to examine the effect of metformin on regulating odontoblast differentiation in MDPC-23 mouse odontoblastic cells derived from mouse dental papilla cells. As compared to controls, metformin significantly accelerated the mineralization, significantly increased and accelerated the expressions of ALP and Col I mRNAs, and significantly increased the accelerated expressions of DSPP and DMP-1 mRNAs, during differentiation of MDPC-23 cells. There was no alteration in cell proliferation of MDPC-23 cells, on exposure to metformin. These results suggest that the effect of metformin on MDPC-23 mouse odontoblastic cells derived from mouse dental papilla cells, facilitates the odontoblast differentiation and mineralization, without altering the cell proliferation.

• Proceedings of the Korean Vacuum Society Conference
• /
• 2013.02a
• /
• pp.427-427
• /
• 2013

잉크젯 프린팅 방법은 전도성 고분자 물질을 잉크 재료로 사용하여 전자 소자의 전극 패턴을 형성할 수 있으며 비접촉, drop-on-demand 공정으로 현재 많은 관심을 받고 있는 연구 분야이다. Ag는 $1.59{\mu}m{\cdot}cm$의 저항을 나타내는 가장 낮은 저항을 가지고 있는 물질 중의 하나이며, Ag 전도성 잉크는 고전도 패턴의 형성을 위해 현재 많이 사용되고 있는 물질이다. 본 연구에서는 a-IGZO 박막을 채널층으로 사용하여 Ag S/D 전극을 잉크젯 프린팅 방법으로 형성하여 산화물 트랜지스터를 제작하였다. a-IGZO 채널층은 $SiO_2$가 증착된 Si 기판위에 스퍼터링 방식으로 80 nm의 두께로 형성하였다. Ag S/D 전극은 10 pl의 카트리지가 장착된 Fujifilm Dimatix DMP 2800 장비를 사용하여 형성하였으며, 프린팅 후 $130^{\circ}C$로 20분간 열처리를 하였다. Fig. 1은 잉크젯 프린팅된 Ag S/D을 가진 a-IGZO의 트랜지스터 특성을 보여준다. 채널 W/L가 90/$50{\mu}m$ 구간에서 드레인 전압이 50 V 일때, 전계효과이동도 $0.27cm^2$/Vs, 문턱전압 6.03 V, 문턱전압 아래의 기울기 값은 2.06 V/dec를 얻었다. 이와 같은 특성은 잉크젯 프린팅 방법으로 Ag S/D 전극을 형성함으로써 산화물 TFT에서 잉크젯 프린팅 방식의 다양한 응용 가능성을 확인할 수 있었다.

• Analytical Science and Technology
• /
• v.28 no.3
• /
• pp.212-220
• /
• 2015

This study aims to identify the characteristics of phthalates (DMP, DEP, DBP, DEHA, BBP, DEHP, and DNOP) and heavy metals such as lead (Pb), cadmium (Cd), and mercury (Hg) in cosmetics and their containers. Phthalates and heavy metals may be endocrine distruptors. Sixty-five cosmetics were purchased from online and offline stores in Busan. This study developed a simultaneous method for the analysis of phthalates by GC-FID. The results showed that among the 65 cosmetics, DBP, DEHP, and DEP were detected at 20.0%, 7.7%, 1.5%, respectively. The amounts of DBP and DEHP detected in 18 samples were less than 100 μg/g, which satisfies the Regulations of Cosmetic Safety Standards in Korea. In order to detect phthalates in cosmetic containers, a dissolution test was conducted by extracting solutions, such as water, n-heptane, 20% ethanol, 50% ethanol and 4% acetic acid, which were prepared with different levels of pH, alcohol content, and fat content following the Korea Standards and Specifications for Utensils, Containers, and Packaging. The results showed that DMP, DBP, DEHA, BBP, DEHP, and DNOP were not detected, DEP was detected in plastics such as PE, PP, and others, when a 50% alcohol solvent was used. Phthalates may not be detected in cosmetic containers if they are not packaged with the above 20% alcohol constituent. We also analyzed the concentration of heavy metals, such as Pb, Cd, and Hg, by using ICP-OES and a mercury analyzer. The ranges of concentration were ND~2.71 μg/g for Pb, ND~0.31 μg/g for Cd, and ND~0.01 μg/g for Hg, which are below the regulated level.

• Biomolecules & Therapeutics
• /
• v.8 no.1
• /
• pp.32-37
• /
• 2000

Recently new soybean saponins with D DMP (2,5-dihydroxy-6-methyl-2,3,- dihydro-4H-pyran-4-one) moiety have been isolated from legumes. The purpose of this study is to characterize ROS scavenging activities of DDMP saponins ($\alpha$g, $\beta$g saponin) isolated from Glycine max (L.) Merrill. The scavenging activity on OH was examined in terms of lipid peroxidation in the rat liver homogenates and the same activity on $O_2$ was also determined in the xanthine-xanthine oxidase system, respectively. Up to 0.25 mg DDMP saponins ($\alpha$g and $\beta$g saponins) did not cause any significant effects on the prevention of lipid peroxidation as compared with the control group. In terms of superoxide scavenging activities, 0.25 and 0.5 mg $\alpha$g saponin inhibits only 2.6% and 5.5% (p<0.05) of the control group, respectively. However, $\alpha$g saponin dose-dependently (p<0.01, r=0.955) inhibits the formation of superoxide radical unto 21.3% of the control group with a maximal dose of 0.5 mg (p<0.01), equivalent to 0.17 units of superoxide dismutase activity.