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http://dx.doi.org/10.5806/AST.2015.28.3.212

The analysis of endocrine distruptors in commercial cosmetics  

Koo, Heesoo (Busan Metropolitan City Institute of Health and Enviroment Department of Health Research Drug Analysis Division)
Na, Youngran (Busan Metropolitan City Institute of Health and Enviroment Department of Health Research Drug Analysis Division)
Lee, Seungju (Busan Metropolitan City Institute of Health and Enviroment Department of Health Research Drug Analysis Division)
Min, Sangkee (Busan Metropolitan City Institute of Health and Enviroment Department of Health Research Drug Analysis Division)
Kang, Jungmi (Busan Metropolitan City Institute of Health and Enviroment Department of Health Research Drug Analysis Division)
Jin, Sung Hyun (Busan Metropolitan City Institute of Health and Enviroment Department of Health Research Drug Analysis Division)
Publication Information
Analytical Science and Technology / v.28, no.3, 2015 , pp. 212-220 More about this Journal
Abstract
This study aims to identify the characteristics of phthalates (DMP, DEP, DBP, DEHA, BBP, DEHP, and DNOP) and heavy metals such as lead (Pb), cadmium (Cd), and mercury (Hg) in cosmetics and their containers. Phthalates and heavy metals may be endocrine distruptors. Sixty-five cosmetics were purchased from online and offline stores in Busan. This study developed a simultaneous method for the analysis of phthalates by GC-FID. The results showed that among the 65 cosmetics, DBP, DEHP, and DEP were detected at 20.0%, 7.7%, 1.5%, respectively. The amounts of DBP and DEHP detected in 18 samples were less than 100 μg/g, which satisfies the Regulations of Cosmetic Safety Standards in Korea. In order to detect phthalates in cosmetic containers, a dissolution test was conducted by extracting solutions, such as water, n-heptane, 20% ethanol, 50% ethanol and 4% acetic acid, which were prepared with different levels of pH, alcohol content, and fat content following the Korea Standards and Specifications for Utensils, Containers, and Packaging. The results showed that DMP, DBP, DEHA, BBP, DEHP, and DNOP were not detected, DEP was detected in plastics such as PE, PP, and others, when a 50% alcohol solvent was used. Phthalates may not be detected in cosmetic containers if they are not packaged with the above 20% alcohol constituent. We also analyzed the concentration of heavy metals, such as Pb, Cd, and Hg, by using ICP-OES and a mercury analyzer. The ranges of concentration were ND~2.71 μg/g for Pb, ND~0.31 μg/g for Cd, and ND~0.01 μg/g for Hg, which are below the regulated level.
Keywords
cosmetics; phthalate; heavy metal; endocrine disruptors; GC-FID;
Citations & Related Records
Times Cited By KSCI : 4  (Citation Analysis)
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1 H. J. Koo and B. M. Lee, Estimated exposue to phthalates in cosmetics and risk assessment, Journal of Toxicology and Environmental Health, Part A, 67, 1901-1014 (2004).   DOI   ScienceOn
2 Ministry of Food and Drug Safety No. 2014-199 (2014. 12. 23.), Republic of Korea.
3 Ministry of Food and Drug Safety No. 2014-27 (2014. 2. 13.), Republic of Korea.
4 H. A. Cha, S. H. Kang, S. B. Choe, H. K. Kim and S. T. Kang, Hazardous Heavy Metal Contents of Mushrooms from Retail Markets in Seoul, Korean J Food Sci Technol, 46(3), 283-287 (2014).   DOI   ScienceOn
5 J. S. Kim, S. W. Hwang, J. M. Kim and J. Y. Ma, Monitoring Research for Heavy Metals as Endocrine Disruptors in Herbal Medicines and Ssangwha-Tang, Korean Journal of Orental Medicine, 6(1), 117-122 (2000).
6 Y. S. Kim, H. J. Jeong, I. S. Chang, Heavy Metals and Cosmetics, J. Soc. Cosmet Scientists Korea, 28(1), 15-30 (2002).
7 J. C. Hubinger and D. C. Havery, Analysis of consumer cosmetic products for phthalate esters, Journal of Cosmetic Science, 57(2), 127-137 (2006).
8 S. R. Choi, Endocrine disruptors of heavy metals and Food, Bulletin of Food Technology, 20(4), 3-10 (2007).
9 K. K. Kim, Contents character of phthalates in school supplies, Analytical Science & Technology, 25(1), 69-75 (2012).   DOI   ScienceOn
10 K. Becker, M. Seiwert, J. Anerer, W. Heger, H. M. Koch, R. Nagorka, E. Rokamp, C. Schluter, B. Seifert and D. Ullrich, International J. of Hygiene and Environ. Health, 207(5), 409-417 (2004).   DOI   ScienceOn
11 W. H. Park, Y. K. Kim, H. J. Jeong, B. C. Choe, K. A. Park, J. K. Lee, I. S. Yu and N. J. Chough, Seoul Institute of Health and Environment, 43, 174-182 (2007).
12 M. K. Kim, H. J. Jung and I. S. Chang, Simple Method in Trace Analysis of Phthalates in Cosmetics : Analytical Conditions and Skills for Better Results, J. Soc. Cosmet. Scientists Korea, 34(1), 51-55 (2008).
13 F. Mendes and J. Amaral, The endocrine disruptors: a major medical challenge. Food Chem Toxical, 40(6), 781-788 (2002).   DOI   ScienceOn