• 대한한의학방제학회지
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• 제22권1호
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• pp.113-122
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• 2014

Objectives : This study investigated the improvement effects of Pakistani (DF-a) and Chinese Ephedra herba-containing Gangjihwan (DF-b) on nonalcoholic fatty liver disease in a high fat diet-induced obese mouse model. Methods : Eight-week-old C57BL/6N mice were divided into five groups: a normal lean group given a standard diet, an obese control group given a high fat diet, and atorvastatin, DF-a, and DF-b groups given a high fat diet with atorvastatin (10 mg/kg), DF-a (80 mg/kg), and DF-b (80 mg/kg), respectively. After 8 weeks of treatment, body weight gain, blood lipid markers, ALT concentrations, liver weight and histology were examined. Results : 1. Body weight gain was significantly decreased in DF-a, DF-b, and atorvastatin groups compared with control. The extent of decreases was eminent in DF-a group. 2. Circulating concentrations of total cholesterol and LDL-cholesterol were significantly decreased in DF-a, DF-b, and atorvastatin groups compared with control. The decreases were most effective in atorvastatin group. 3. Liver weights were decreased in DF-a, DF-b, and atorvastatin groups compared with control. In particular, liver weight was significantly reduced in DF-b group. 4. Hepatic lipid accumulation was significantly decreased in DF-a, DF-b, and atorvastatin groups compared with control, and the magnitude of which was most effective in DF-b group. 5. Circulating ALT concentrations were decreased in DF-a, DF-b, and atorvastatin groups compared with control, but ALS levels were significantly reduced only in DF-b group. Conclusions : In conclusion, these results suggest that DF-a and DF-b decrease body weight gain, improve blood lipid metabolism, and reduce liver weight and hepatic lipid accumulation, contributing to the improvement of nonalcoholic fatty liver disease. In addition, these effects were similar between Pakistani and Chinese Ephedra herba-containing Gangjihwan.

• 한국통신학회논문지
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• 제21권7호
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• pp.1734-1745
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• 1996

본 논문에서는 디지탈 자기 기록 채널의 비선형 왜곡 보상을 위한 개선된 fixed-delay tree search with decision feedback(FDTS/DF)에 대하여 논한다. 고밀도로 갈수록 두드러지게 나타나는 비선형 왜곡은 일반적으로 이산 Volterra 급수로 잘 모델링되므로 비선형 feedforward 필터, 선형 궤환 필터, 그리고 비선형 왜곡 테이블에 의하여 등화기가 구성되며, 이 때 왜곡 테이블의 값은 미래의 기록 데이터에 의한 비선형 왜곡 영향을 고려하여 결성된다. FDTS를 사용한 결정단에서는 이전의 결정값, 현재의 추정치와 미래의 추정치를 고려하여 최소의 branch metric을 갖는 path가 선택된다. 모의 실험을 통하여 선형 FDTS/DF, 기존의 비선형 FDTS/DF, 그리고 제안된 비선형 FDTS/DF/DF의 성능이 비교되며, 제안된 비선형 FDTS/DF가 고밀도 기록시 가장 우수한 성능을 보임을 확인한다.

• 한국군사과학기술학회지
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• 제14권4호
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• pp.669-675
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• 2011

In this paper, we present the AFP(antenna front plate)s which were designed to reduce the reflection for the sake of the improvement of DF(direction finding) accuracy. The AFP consists of front plate, absorber and radome. The AFPs were optimized respectively by real test and we performed the DF test using our AFPs in laboratory. The DF test shows that the DF accuracy is about 2 times better than the requirement capability. Then, the DF field test was executed using the AFPs, which were installed in helicopter in consideration of the reflection by platform. The result of the DF field test is superior to the requirement capability also, which shows the validity of our design method.

• 한국식품위생안전성학회지
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• 제11권1호
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• pp.7-10
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• 1996

Chicken skins or carcasses inoculated with Salmonella typhimurium were exposed to 0.1 or 0.5% grapefruit seed extracts (DF-100) for 1 or 3 min to evaluate antibacterial activity of DF-100 and its possible application in proultry processing. The numbers of live salmonellae on chicken skins were reduced by 0.8-1.2 logs/cm2 with 0.5% DF-100. Dipping chicken carcasses into 0.5% DF-100 for 3 min reduced salmonelae by 4.3 logs/carcass. Scanning electron microscopy showed that DF-100 killed the cells attached but did not detach cells from the skin. No odor or changes in the color of chicken skin were detected after DF-100 treatment.

• 한국추진공학회:학술대회논문집
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• 한국추진공학회 2004년도 제23회 추계학술대회 논문집
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• pp.9-12
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• 2004

수치해석을 통하여 불화중수소 화학레이저의 연료 및 산화제 분사 압력 비에 따른 밀도반전 등의 레이저 발진 성능 특성 변화에 대하여 알아보았다. 이 현상은 DF 여기분자의 분포 및 최대 소신호 이득계수, 레이저빔 출력에 대한 분석을 통해 해석이 이루어진다. 본 연구의 주요 결과로써, $D_2$ 분사 압력이 높아질수록 불화중수소 화학레이저 발진에서 중요한 부분을 차지하는 $DF^{(1)}-DF^{(0)}$ 진동 에너지 전이에서, 강한 레이저빔을 생성할 수 있는 여기분자 분포 및 최대 소신호 이득계수가 나타난다.

• 대한한의학방제학회지
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• 제22권1호
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• pp.167-176
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• 2014

Objectives : This study investigated the improvement effects of Gangjihwan (DF) and combination of Gangjihwan and Gamisochehwan (GSH) on nonalcoholic fatty liver disease in a high fat diet-induced obese mouse model. Methods : Eight-week-old C57BL/6N mice were divided into five groups: a normal lean group given a standard diet, an obese control group given a high fat diet, and atorvastatin, DF, and DF+GSH groups given a high fat diet with atorvastatin (10 mg/kg), DF (40 mg/kg), and DF+GSH (80 mg/kg), respectively. After 8 weeks of treatment, body weight gain, blood lipid markers, ALT concentrations, liver weight and histology were examined. Results : 1. Body weight gain was significantly decreased in DF, DF+GSH and atorvastatin groups compared with control. The extent of decreases was eminent in DF+GSH group. 2. Circulating concentrations of total cholesterol, HDL-cholesterol and LDL-cholesterol were decreased in DF, DF+GSH and atorvastatin groups compared with control. The decreases were significant in DF+GSH and atorvastatin groups. 3. Liver weights were decreased in DF, DF+GSH and atorvastatin groups compared with control. In particular, liver weight was significantly reduced only in DF+GSH group. 4. Hepatic lipid accumulation was significantly decreased in DF, DF+GSH and atorvastatin groups compared with control, and the magnitude of which was more effective in DF+GSH group than in DF-only group. 5. Circulating ALT concentrations were decreased in DF, DF+GSH and atorvastatin compared with control, but ALS levels were significantly reduced only in DF+GSH group. Conclusions : In conclusion, these results suggest that DF decreases body weight gain, improves blood lipid metabolism, and reduces liver weight and hepatic lipid accumulation, contributing to the improvement of nonalcoholic fatty liver disease. In addition, these effects were more effective in DF+GSH combination group than in DF-only group.

• 대한한의학방제학회지
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• 제25권2호
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• pp.193-207
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• 2017

Objectives : This study was designed to investigate anti-obesity effects of DF in a ob/ob mouse model. Methods : Fifteen-week-old ob/ob mice were divided into four groups: a normal lean group given a standard diet, an ob/ob control group given a standard diet, and DF(1) and DF(2) groups given a standard diet with DF(1) (300 mg/kg), and DF(2) (600 mg/kg), respectively. After 10 weeks of treatment, body weight gain, feeding efficiency ratio, blood lipid markers, fat weight and histology were examined. Results : Body weight gain and fat mass were significantly decreased in DF(1) and DF(2) groups compared with control. The extent of decreases was eminent in DF(2) group. Feeding efficiency ratio were significantly decreased in DF(2) group compared with control. Consistent with their effects on body weight gain and fat mass, circulating concentrations of LDL, total cholesterol, free fatty acid, and insulin were decreased in DF(2) group compared with control. The size of adipocytes were significantly decreased by DF(2) compared with control. Consistent with their effects on body weight gain, hepatic lipid accumulation and liver weights were reduced in DF compared with control. Conclusions : In conclusion, these results suggest that DF not only decrease feeding efficiency ratio, and blood anti-obesity biomarkers, but also reduce fat mass, contributing to the improvement of obesity. DF also inhibits hepatic lipid accumulation.

• 한국추진공학회:학술대회논문집
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• 한국추진공학회 2004년도 제22회 춘계학술대회논문집
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• pp.287-293
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• 2004

A numerical simulation is presented for investigating the effects of pressure ratio of $D_2$ injector to supersonic nozzle on the population inversion in the DF chemical laser cavity, while a lasing concurrently takes place. The laser beam is generated between the mirrors in the cavity and it is important to obtain stronger population inversion and more uniform distribution of the excited molecules in the laser cavity in order to produce high power laser beam with good quality. In this study, these phenomena are investigated by means of analyzing the distributions of the DF excited molecules and the F atom used as an oxidant, while simultaneously estimating the maximum small signal and saturated gains and power in the DF chemical laser cavity. For the numerical solution, an 11-species (including DF molecules in various excited states of energies), 32-step chemistry model is adopted for the chemical reaction of the DF chemical laser system. The results are discussed by comparison with two $D_2$injector pressure cases; 192 torr and 388.64 torr. Major results reveal that in the resonator, stronger population inversions occur in the all transitions except DF(1)-DF(0), when the $D_2$injection pressure is lower. But, the higher $D_2$injection pressure provides a favorable condition for DF(1)-DF(0) transition to generate the higher power laser beam. In other words, as the pressure of $D_2$injector increases, the maximum small signal gain in the $V_{1-0}$ transition, which is in charge of generating most of laser power, becomes higher. Therefore, the total laser beam power becomes higher.r.

• 대한한의학방제학회지
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• 제22권2호
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• pp.105-120
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• 2014

Objectives : This study was investigated the improvement effects of Gangjihwan (DF) and combination of Gangjihwan and Gamisochehwan (GSH) on obesity in a high fat diet-fed obese mouse model. Methods : Eight-week-old C57BL/6N mice were divided into four groups: a normal lean group given a standard diet, an obese control group given a high fat diet, and DF and DF+GSH groups given a high fat diet with DF (40 mg/kg), and DF+GSH (80 mg/kg), respectively. After 8 weeks of treatment, body weight gain, feeding efficiency ratio, blood lipid markers, fat weight and histology were examined. Results : 1. Body weight gain and fat mass were significantly decreased in DF and DF+GSH groups compared with control. The extent of decreases was eminent in DF+GSH group. 2. Feeding efficiency ratio and circulating concentration of leptin were decreased in DF and DF+GSH groups compared with control. These decreases were significant in DF+GSH group. 3. Consistent with their effects on body weight gain and fat mass, circulating concentrations of triglyceride, glucose and insulin were decreased in DF and DF+GSH groups compared with control. 4. The size of adipocytes was decreased by DF and DF+GSH compared with control, whereas the adipocyte number per unit area was increased by them, suggesting that DF and DF+GSH decreased the number of large adipocytes. 5. Consistent with their effects on body weight gain, liver fibrosis was also improved in DF and DF+GSH groups compared with control. Conclusions : In conclusion, these results suggest that DF and DF+GSH groups decrease feeding efficiency ratio, plasma leptin concentration, blood anti-obesity biomarkers and fat mass, improves body weight gain contributing to the inhibition of liver fibrosis. In addition, these effects were more effective in DF+GSH combination group than in DF-only group.

• 한국산학기술학회논문지
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• 제12권11호
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• pp.5208-5213
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• 2011

본 논문에서는 배열안테나에 도달한 전파의 위상차와 시간차를 이용하여 방향탐지 정확도가 높고 방향모호성이 없는 새로운 방향탐지 기술을 제안하였다. 21세기의 전자정보시스템에는 배열 안테나에 도달하는 신호의 위상차를 이용하는 위상차 방향탐지 방식 또는 배열안테나에 도달하는 신호도착 시간차를 이용하는 방향탐지 방식이 주로 사용되고 있다. 시간차를 이용하는 방식은 장치구성은 간단하지만 좁은 안테나 배치공간에서는 방향탐지 정확도가 나쁘고, 위상차 방식은 좁은 안테나 배치공간에서도 방향탐지 정확도는 높으나 방향모호성이 발생한다. 본 논문에서는 두 방식의 장점을 결합한 방향탐지 정확도가 높고 방향모호성이 없는 새로운 방향탐지 기술을 제안하였으며, 실제 운용환경과 유사한 잡음환경에서 방향탐지 오차를 모사하여 제안된 방식의 우수성을 입증하였다.