• 대한기계학회논문집A
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• 제29권11호
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• pp.1439-1444
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• 2005

A two-dimensional boundary element method was used for the scattering analysis of side-drilled hole(SDH). The far-field scattering amplitude was calculated for shear vertical(SV) wave, and their frequency and time-domain results were presented. The time-domain scattering amplitude showed the directly reflected wave from the SDH leading edge as well as the creeping wave. In an immersion, pulse-echo testing, two measurement models were introduced to predict the response from SDHs. The 2-D boundary element scattering amplitude was converted to the 3-D amplitude to be used in the measurement model. The receiver voltage was calculated fer SV wave incidence at 45$^{\circ}C$ on the 1 m diameter SDH, and the result was compared with experiment.

• Journal of the Korean Society for Industrial and Applied Mathematics
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• 제15권2호
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• pp.143-150
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• 2011

We consider the global existence of strong solutions of the 3D incompressible Navier-Stokes equations in a thin periodic domain. We present a simple proof that a strong solution exists globally in time when the initial velocity in $H^1$ and the forcing function in $L^p$(0,${\infty}$;$L^2$), $2{\leq}p{\leq}{\infty}$ satisfy certain condition. This condition is basically similar to that by Iftimie and Raugel[7], which covers larger and larger initial data and forcing functions as the thickness of the domain ${\epsilon}$ tends to zero.

• 대한수학회지
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• 제49권2호
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• pp.315-324
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• 2012

We consider the global existence of strong solutions of the 3D incompressible Navier-Stokes equations in a long periodic domain. We show by a simple argument that a strong solution exists globally in time when the initial velocity in $H^1$ and the forcing function in $L^p$([0; T);$L^2$), T > 0, $2{\leq}p{\leq}+\infty$ satisfy a certain condition. This condition common appears for the global existence in thin non-periodic domains. Larger and larger initial data and forcing functions satisfy this condition as the thickness of the domain $\epsilon$ tends to zero.

• 한국전자파학회논문지
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• 제13권1호
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• pp.94-100
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• 2002

본 논문에서는 N개의 평행 결합선로를 이용한 3 dB 결합기를 해석하였으며, 유도된 식에 의하여 최소의 결합선로 수와 크기로 설계하였다. 기존의 Spectral Domain상에서 N단 평행 결합선로의 4N-port의 산란행렬로부터 port reduction 방법을 사용하여 4-port 산란 행렬을 유도하였으며, 유도된 결과의 타당성을 검증하기 위하여 실제 제작하고 측정하였다. 제작된 결합기는 loose coupling의 평행 결합 선로를 이용하기 때문에 Lange Coupler 와 같은 높은 임피던스와 Tight coupling을 구현할 필요가 없으며, wire bonding포 용이하다. 최소의 단수로 구현하기 위해 높은 유전율과 두꺼운 기판을 사용하여 2단으로 3 dB 구현이 가능함을 제시하였다. 제작결과 3.6 GHz에서 5.5 GHz로 대략 42 %(0.5 dB unbalance) 정도의 광대역 특성을 가지고 위상차도 1$^{\circ}$내외의 결합기를 구현할 수 있었고 격리도 특성 또한 대역 내에서 15 dB 내외의 특성을 보였다.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2001년도 제14회 신호처리 합동 학술대회 논문집
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• pp.513-516
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• 2001

마이크로폰을 배열을 이용한 음성개선 기법 중에서 저주파 영역에서의 높은 상관성과 고주파 영역에서의 spatial aliasing을 동시에 고려하기 위하여 대수적인 선형 마이크로폰 배열을 사용하고 웨이브렛 도메인에서의 Wiener 필터에 기반한 postfiltering을 수행하는 방법이 제안된 바 있는데[l], 본 논문에서는 이 방법의 문제점을 분석하고 해결방안을 제시하였다. 제안한 알고리즘을 사용하여 시뮬레이션한 결과, 마이크에 입력되는 음성신호의 SNR이 0dB일 때와 l0dB일 때, 기존의 알고리즘에 비해 약 1.7dB와 2.5dB의 성능개선이 있었으며, 청취실험을 통해서도 음질의 향상을 확인할 수 있었다.

• 기술혁신학회지
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• 제2권3호
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• pp.1-18
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• 1999

The purpose of this research is to analyze the influence of the factors on the performance of na-tional R&D support program. A LISREL model was employed to analyze the relationship between the factors and the performance which was measured in the technological and commercial aspect. The result of the study reveals the R&D management business administration the age and the size of the company industry domain are the factors whose relationship with the performance are sta-tistically significant.

• Journal of applied mathematics & informatics
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• 제28권5_6호
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• pp.1315-1322
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• 2010

Let D be a plane domain whose boundary consists of n components and $C_1$, $C_2$ two boundary components of D. We consider the family $F_1$ of conformal mappings f satisfying f(D) $\subset$ {1 < |w| < ${\mu}(f)$}, $f(C_1)=\{|w|=1\}$, $f(C_2)=\{|w|={\mu}(f)\}$. There are conformal mappings $g_0$, $g_1({\in}F_1)$ onto a radial and a circular slit annulus respectively. We obtain the following theorem, $$\{{\mu}(f)|f\;{\in}\;F_1\}=\{\mu|\mu(g_1)\;{\leq}\;{\mu}\;{\leq}\;{\mu}(g_0)\}$$. And we consider the family $F_n$ of conformal mappings $\tilde{f}$ from D onto a covering surfaces of the Riemann sphere satisfying some conditions. We obtain the following theorems, {$\mu|1$ < ${\mu}\;{\leq}\;{\mu}(g_1)$} ${\subset}\;\{{\mu}(\tilde{f})|\tilde{f}\;{\in}\;F_2\}\;{\subset}\;\{{\mu}(\tilde{f})|\tilde{f}\;{\in}\;F_n\}$ and ${\mu}(\tilde{f})\;{\leq}\;{\mu}(g_0)^n$.

• Journal of Microbiology and Biotechnology
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• 제8권2호
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• pp.152-157
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• 1998

To analyze the role of the C and D domains in the cyclization activity of cyclodextrin glucanotransferase (CGTase), two plasmids, pKB1ΔC300 and pKB1ΔD96, were constructed in which DNA regions encoding 100 and 32 amino acids, respectively, from the C and D domains of B. stearothermophilus NO2 CGTase were deleted. The mutated CGTase from the pKBlΔC300 produced much lower amounts of ${\alpha}$-, ${\beta}$-, and $\gamma$-cyclodextrin (CD) than the parental CGTase. However, the mutated CGTase from the pKBlΔD96 showed a similar production pattern of CDs to wild-type CGTase. The production ratios of the ${\alpha}$-, ${\beta}$- and $\gamma$-CDs were not affected by the deletions, when compared to those of parental CGTase. The optimum temperature of the mutated CGTase from the pKBlΔC300 was decreased from $60^{\circ}C$ to $55^{\circ}C$. The optimum pH of the mutated CGTase from the pKB1D96 was shifted from 6.0 to 7.0. The thermostability of the two mutant CGTases were not changed. From these results, it is suggested that the C and D domains are not related to cyclization activity directly because mutant-enzymes deleted C or D domains still possessed their activity. However, they are important for other enzymatic properties such as productivity and pH optimum as a partition of CGTase tertiary structure.

• 미생물학회지
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• 제40권2호
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• pp.87-93
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• 2004

세포질과 핵단백질의 serine과 threonine 잔기에 O-linked N-acetyl-$\beta$-glucosamine (O-GlcNAc)의 첨가는고등 진핵 세포에서 흔히 일어나는 번역 후 단백질의 변형 중 하나로서 단백질의 인산화와 유사한 세포 내 신호전달에 관여하는 것으로 보인다. O-GlcNAc의 첨가와 제거는 O-GlcNAc transferase (OGT)와 O-linked N-acetyl-$\beta$-D-glucos-aminidase (O-GlcNAcase) 효소에 의해 각각 촉매된다. 두가지 종류의 사람 유래 O-GlcNAcase 유전자(O-GlcNAcase, v-O-GlcNAcase)를cloning하고 세 가지의 융합단백질로 대장균에서 생산을 시도하였다. O-GlcNAcase의 기질 유사체 인 ${\rho}$-nitrophenyl-N-acetyl-$\beta$-D-g1ucosaminide (${\rho}$NP-$\beta$-D-GlcNAc)를 기질로 사용하여 효소활성을 측정 한 결과 v-O-GlcNAcase는 활성을 나타내지 않았다. 여러 종류의 amino sugar 기질 유사체를 사용하여 O-GlcNAcase의 활성을 측정하였으나 오직 ${\rho}$NP-$\beta$-D-GlcNAc만이 활성을 보였다. Blast검색으로 분석한 결과 아미노 말단의 hyaluronidase-like domain (hyaluronidase-유사 영역)과 카르복시 말단의 N-acetyltransferase 영역 두 곳의 conserved domains 존재하였다. 효소촉매에 중요한 영역을 밝히기 위해 여러 deletion mutants(결손 변이체)를 제작한 후 효소활성을 측정하고 Western blot으로 분석하였다. Hyaluronidas-유사 영역, 유전자 내부와 N-acetyltransferase 영역을 제거할 경우 효소활성이 사라졌으나 아미노 말단의 55개 아미노산과 카르복시 말단의 truncation은 활성을 일부분 유지하였다. 위의 사실에 기초하여 hyaluronidas-유사 영역은 효소활성에 중요하고 카르복시 말단의 N-acetyltransferase 영역은 조절기능으로 작용하는 것으로 추정된다.

• Journal of Microbiology and Biotechnology
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• 제22권6호
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• pp.788-792
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• 2012

We report the computational structural simulation of the Cry1Ab19 toxin molecule from B. thuringiensis BtX-2 based on the structure of Cry1Aa1 deduced by x-ray diffraction. Validation results showed that 93.5% of modeled residues are folded in a favorable orientation with a total energy Z-score of -8.32, and the constructed model has an RMSD of only $1.13{\AA}$. The major differences in the presented model are longer loop lengths and shortened sheet components. The overall result supports the hierarchical three-domain structural hypothesis of Cry toxins and will help in better understanding the structural variation within the Cry toxin family along with facilitating the design of domain-swapping experiments aimed at improving the toxicity of native toxins.