• Journal of the Korean Society of Food Science and Nutrition
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• v.38 no.7
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• pp.935-945
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• 2009

This study was performed to find the optimum ratio of ingredients in the Chinese quince jam. The experiment was designed according to the D-optimal design of mixture design, which included 14 experimental points with 4 replicates for three independent variables (Chinese quince paste $45{\sim}60%$, pectin $1.5{\sim}4.5%$, sugar $45.5{\sim}63.5%$). A mathematical analytical tool was employed for the optimization of typical ingredients. The canonical form and trace plot showed the influence of each ingredient in the mixture against final product. By use of F-test, sweetness, pH, L, b, ${\Delta}E$, and firmness were expressed by a linear model, while the spreadmeter value, a, and sensory characteristics (appearance, color, smell, taste, and overall acceptability) were by a quadratic model. The optimum formulations by numerical and graphical method were similar: Chinese quince paste 54.48%, pectin 2.45%, and sugar 53.07%. Optimum ingredient formulation is expected to improve use of Chinese quince and contribute to commercialization of high quality Chinese quince jam.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.8 no.3
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• pp.673-681
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• 2007

The integration of Quality Circles and Six-Sigma has gained attentions for the attainment of enhanced customer satisfaction, costs reduction, and improved business performance. The purpose of this paper is to verify the benefit from the integration of Quality Circles and Six-Sigma by applying the integrated process for an alcohol manufacturing line. In the integrated process, we used the first three steps of Six-Sigma of Define, Measure, and Analyze(D-M-A) and then applied the concept of Quality Circle, which has good performance in the Improvement and Control(I-C) process. For the selection of the theme of quality circles, Analytic Hierarch Process(AHP) is used, and we also employed the experimental design, which is designed to find an optimal operating condition. Furthermore, the results of the economic analysis confirm that the integration process would be successful in reducing the incidence of defects and the quality cost.

• Magazine of the Korean Society of Agricultural Engineers
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• v.40 no.5
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• pp.68-79
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• 1998

In the years, the concern about high-strength concrete which is new material has been heightened as a result of active research and development. Recently, as the building structure has been being bigger, higher, longer and more specialized, the demand of material with high-strength concrete for building has been increasing. The demand of high -strength concrete is expected to increase with expansion of usage about the complex concrete structures such as bridge structure as well as nuclear plants, underground structures, hydraulic structures and arctic area sturctures. In this research, silica-fume was used as an admixture in order to get a high-strength concrete. Water/binder ration was limited no more than 18 percent and the amount of unit cement was increased. In this study, a number of trial in concrete mix was carried out to get optimal mix design, and the target slump with $10{\pm}2cm$ was set for in-situ construction. High-strength concrete with cylinder strength of 1,200kgf/$cm^2$ in the 28-days was produced and tested. The static test was carried out to measure the ultimate load, the initial load of flexural and diagonal cracking, crack patterns, fracture modes. The load versus strain and load versus deflection relations were obtained form the static test. The test results were compared with the shear strengths predicted by the equations of ACI code 318-89 and orther researchers. Based on the test results, shear strength equation of reinforced concrete beam using high strength concrete was proposed. Form an evaluation of the results of this experimental investigation, it was concluded that shear strength after diagonal tention cracking diminished with the increase in compressive strength for beams.

• Transactions of the Korean Society of Automotive Engineers
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• v.12 no.6
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• pp.38-45
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• 2004

This paper studies the effects of intake port configuration on the swirl that is key parameter in the flow field of direct injection diesel engines. In-cylinder flow characteristics is known to have significant effects on fuel air mixing, combustion and emissions. To investigate the swirl flow generated by various intake ports, steady state flow tests were conducted to evaluate the swirl. Helical port geometry, SCV shape and bypass were selected as the design parameters to increase the swirl flow and parametric study was performed to choose the optimal port shape that would generate a high swirl ratio efficiently. The results revealed that a key factor in generating a high swirl ratio was to suitably control the direction of the intake air flow passing through the valve seat. For these purposes, we changed the distance of helical and tangential port as well as installed bypass near the valve seat and the effects of intake port geometry on in-cylinder flow field were visualized by a laser sheet visualization method. From the experimental results, we found that the swirl ratio and mass flow rate had a trade off relation. In addition, the result indicates that the bypass is a effective method to increase the swirl ratio without sacrificing mass flow rate.

• Journal of the Korean Society of Food Science and Nutrition
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• v.32 no.8
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• pp.1270-1277
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• 2003

The extrusion conditions of the soymilk residue and corn grits mixtures were optimized. The experiment was designed according to the D-optimal design of response surface methodology (RSM), which shows 18 experimental points including 4 replicates for three independent variables (screw speed, water content and die temperature). The responses variables such as bending force, expansion ratio, bulk density, water solubility index (WSI), water absorption index (WAI), and color values (L＊, a＊, b＊) were evaluated using response surface analysis. Expansion ratio and WSI decreased with increasing water content, whereas bulk density tended to increase with increasing water content. While greater screw speeds enhanced WSI and yellowness, higher moisture contents decreased the expansion ratio and WSI value. However, die temperature did not influence upon the response variables. The optimum extrusion conditions by numerical and graphical methods were similar: the screw speed, water content, and die temperature were 250 rpm, 22.43% and l28.16$^{\circ}C$ by the numerical method; 250 rpm, 22.43%, and 128.02$^{\circ}C$ by graphical method.

• Journal of Ginseng Research
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• v.46 no.2
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• pp.283-289
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• 2022

Background: Sarcopenia, defined as loss of muscle mass and strength with age, becomes a public health concern as the elderly population increases. This study aimed to determine whether the mixture of soluble whey protein hydrolysate (WPH) and Panax ginseng berry extract (GBE) has a synergetic effect on sarcopenia and, if so, to identify the relevant mechanisms and optimal mixing ratio. Methods: In the first experiment, C57BL/6 mice were hindlimb immobilized for one-week and then administered WPH 800 mg/kg, GBE 100 mg/kg, WPH 800 mg/kg+ GBE 100 mg/kg mixture, and Fructus Schisandrae extract (SFE) 200 mg/kg for two weeks. In the second experiment, experimental design was same, but mice were administered three different doses of WPH and GBE mixture (WPH 800 mg/kg+ GBE 100 mg/kg, WPH 800 mg/kg+ GBE 90 mg/kg, WPH 1000 mg/kg+ GBE 75 mg/kg). Results: In the first experiment, we confirmed the synergetic effect of WPH and GBE on muscle mass and identified that GBE was more effective on the protein synthesis side, and WPH tended to be slightly more effective for protein degradation. In the second experiment, among three different ratios, the WPH 800 mg/kg+ GBE 100 mg/kg was most effective for muscle mass and strength. The mixtures activated muscle protein synthesis via PI3K/Akt/mTORc1 pathway and inhibited muscle protein degradation via suppressing ubiquitin-proteasome system (UPS) and autophagy-lysosome system (ALS), and these effects were more GBE dose-dependent than WPH. Conclusion: The WPH and GBE mixture having a synergetic effect is a potential agent to prevent sarcopenia.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.41 no.7
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• pp.645-653
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• 2017

In bone tissue engineering, polycaprolactone (PCL) is one of the most widely used biomaterials in the manufacturing of scaffolds as a synthetic polymer having biodegradability and biocompatibility. The strut width in the fabrication of scaffolds is an important part of tissue regeneration in in-vitro and in-vivo experiments, because it affects not only the pore size but also the porosity. In this study, we used polymer deposition system (PDS) and design of experiments (DOE) to explore the optimal process conditions to achieve a systematic and efficient scaffold manufacturing process, using temperature, pressure, scan velocity, and nozzle tip height as the parameters for the experiments. The aim of this research was to fabricate a 3D PCL scaffold having a uniform strut width of $150{\mu}m$ using DOE; it was proved that the strut width was constant in all the experimental groups by fabricating the PCL scaffolds according to various pore patterns as well as one pore pattern.

• Journal of Soil and Groundwater Environment
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• v.18 no.1
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• pp.26-35
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• 2013

Outbreak of animal infectious diseases such as foot-and-mouth disease, avian influenza are becoming prevalent worldwide. For prevent the further infection, tremendous numbers of the infected or culled stocks are buried around farm. This burial method can generate a wide range of detrimental components such as leachate, nutrient, salt, and pathogenic bacteria, consequently. In this study, for the stabilization of livestock carcasses leachate, advanced oxidation processes utilizing the Fenton reaction was investigated in lab-scale experiments for the treatment for $COD_{Cr}$ of livestock carcass leachate. $COD_{Cr}$ reduction by the Fenton oxidation was investigated response surface methodology using the Box-Begnken methods were applied to the experimental results. A central composite design was used to investigate the effects of the independent variables of pH ($x_1$), dosage of $FeCl_2{\cdot}4H_2O$ ($x_2$) and dosage of $H_2O_2$ ($x_3$) on the dependent variables $COD_{Cr}$ concentration ($y_1$). A 1 M NaOH and $H_2SO_4$ was using for pH control, $FeCl_2{\cdot}4H_2O$ was used as iron catalyst and NaOH was used for Fenton reaction. The optimal conditions for Fenton oxidation process were determined: pH, dosage of $FeCl_2{\cdot}4H_2O$ and dosage of $H_2O_2$ were 3, 0.6 g (0.0151 M) and 7 mL(0.259 M), respectively. Statistical results showed the order of significance of the independent variables to be pH > initial concentration of ferrous ion > initial concentration of hydrogen peroxide.

• Asian-Australasian Journal of Animal Sciences
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• v.20 no.11
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• pp.1705-1712
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• 2007

The effect of different tropical feed sources on rumen ecology, cellulolytic bacteria, feed intake and digestibility of beef cattle was investigated. Four fistulated, castrated male crossbred cattle were randomly allocated to a $4{\times}4$ Latin square design. The treatments were: T1) urea-treated (5%) rice straw (UTS); T2) cassava hay (CH); T3) fresh cassava foliage (FCF); T4) UTS:FCF (1:1 dry matter basis). Animals were fed concentrates at 0.3% of body weight on a DM basis and their respective diets on an ad libitum basis. The experimental period was 21 days. The results revealed that the use of UTS, CH, FCF and UTS:FCF as roughage sources could provide effective fiber and maintain an optimal range of ruminal pH and $NH_3-N$. Total viable and cellulolytic bacterial populations were enhanced (p<0.05) with UTS as the roughage source. Animals fed FCF had a higher rumen propionate production (p<0.05) with a lower cellulolytic bacteria count. Moreover, three predominant cellulolytic bacteria species, namely Fibrobacter succinogenes, Ruminococcus albus and Ruminococcus flavefaciens, were found in all treatment groups. Roughage intake and total DM intake were highest with UTS (2.2 and 2.5% BW, respectively) as the roughage source (p<0.05). Nutrient intake in terms of organic matter intake (OMI) was similar in UTS, CH and UTS:FCF treatments (8.0, 6.8 and 8.7 kg/d, respectively), while crude protein intake (CPI) was enhanced in CH, FCF and UTS:FCF as compared to the UTS treatment (p<0.05). Digestion coefficients of DM and organic matter (OM) were similar among treatments, while the CP digestion coefficients were similar in CH, FCF and UTS:FCF treatments, but were higher (p<0.05) in CH than in UTS. CP and ADF digestible intakes (kg/d) were highest (p<0.05) on the CH and UTS treatments, respectively. It was also observed that feeding FCF as a full-feed resulted in ataxia as well as frequent urination; therefore, FCF should only be fed fresh as part of the feed or be fed wilted. Hence, combined use of FCF and UTS as well as CH and FCF were recommended.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.35 no.12
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• pp.1285-1292
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• 2011

The characteristics of a semiconductor chiller system with EEV have been experimentally studied. Three experiments on temperature changes (increase and decrease), load variation, and control precision were conducted to investigate the operating characteristics of the semiconductor chiller. The power consumption was 8.9 kW during increase in temperature. The required time was 37.5 min for CH1 and 39.5 min for CH2. Moreover, the time required for falling temperature was 26.5 min. The control precision for partial load operation was relatively low compared to that of a full load operation. In addition, the CH2 equipped with a step motor showed better control precision. The power consumed by the chiller for process cooling water was 1.8 kW, which was one-half of that consumed during the refrigeration cycle. The objective of this study is to provide an optimal control guideline for the semiconductor chiller design.