• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.15 no.9
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• pp.808-811
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• 2002

We investigated response characteristics of twisted nematic (TN) cell with different nematic liquid crystals (NLCs) and cell gap d on a rubbed polyimide (PI) surface. High transmittance and fast response time of the TN cell on the rubbed PI surface were achieved by using high birefringence (Δn) and low cell gap d. The response time of TN cell on the rubbed PI surface was measured 5.1 ms. The transmittance and response time of the TN cell on the rubbed PI surface decreased with decreasing Δnd.

• Journal of Integrative Natural Science
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• v.9 no.1
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• pp.41-61
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• 2016

Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related mortality worldwide. Phosphoinositide 3-kinases (PI3Ks) play important role in Non-Small Cell Lung Cancer. PI3Ks constitute a lipid kinase family which modulates the function of numerous substrates involved in the regulation of cell survival, cell cycle progression and cellular growth. Herein, we describe the ligand based pharmacophore combined with molecular docking studies methods to identify new potent PI3K inhibitors. Several pharmacophore models were generated and validated by Guner-Henry scoring Method. The best models were utilized as 3D pharmacophore query to screen against ZINC database (Chemical and Natural) and the retrieved hits were further validated by fitness score, Lipinski's rule of five. Finally four compounds were found to have good potential and they may act as novel lead compounds for PI3K inhibitor designing.

• Bulletin of the Korean Mathematical Society
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• v.32 no.1
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• pp.45-56
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• 1995

D. H. Gottlieb [1, 2] studied the subgroups $G_n(X)$ of homotopy groups $\pi_n(X)$. In [5, 7, 10], the authors introduced subgroups $G_n(X, A)$ and $G_n^{Rel}(X, A) of \pi_n(X)$ and $\pi_n(X, A)$ respectively and showed that they fit together into a sequence $$ \cdots \to G_n(A) \longrightarrow^{i_*} G_n(X, A) \longrightarrow^{j_*} G_n^{Rel}(X, A) \longrightarrow^\partial $$ $$ \cdots \to G_1^{Rel}(X, A) \to G_0(A) \ to G_0(X, A) $$ where $i_*, j_*$ and \partial$ are restrictions of the usual homomorphisms of the homotopy sequence $$ \cdot \to^\partial \pi_n(A) \longrightarrow^{i_*} \pi_n(X) \longrightarrow^{j_*} \pi_n(X, A) \to \cdot \to \pi_0(A) \to \pi_0(X) $$.

• Journal of Life Science
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• v.12 no.6
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• pp.752-758
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• 2002

This study was investigated on properties and thermostability of gelatin-degrading proteinases in the fruit of Actinidia chinensis (kiwifruit) for the industrial application. Three gelatin-degrading proteinases (PI, PII and PIII) were detected from the pulp of fruits. The molecular weights of these proteinases, PI, PII and PIII, were approximately 220 kD, 51 kD, and 26 kD respectively, on the basis of gelatin-containing SDS-PACE. The optimum pH of these proteinases ranged from 2.0 to 5.0 with a maximal activity at pH 4.0. These proteinases had a high sensitivity to E-64 and iodoacetate which are cysteine protease inhibitors, and required DTT, cysteine, and $\beta$-mercaptoethanol for their activities which are stimulators for cysteine proteases. These results indicate that these proteinases are cysteine proteinases and the proteinase PIII is actinidin (EC 3.4.22.14), based on the molecular weight and/or susceptibility against proteinase inhibitors. These proteinases were strongly activated by $Ca^{2+}$, $Mg^{2+}$ and $Mn^{2+}$, whereas strongly inhibited by Zn$^{2＋}$ and Hg$^{2＋}$. However, these proteinases have slightly different susceptibility against other cations ($Ca^{2+}$, $Cu^{2+}$, $Al^{3+}$, $Ca^{3+}$. The temperature stability of proteinase PIII was more stable than proteinases PI and PII. Moreover, proteinase PIII remained stable below $50^{\circ}C$ for 48hr, showing the residual activity above 75% of the enzyme activity.

• Journal of the Korean Graphic Arts Communication Society
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• v.29 no.1
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• pp.61-74
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• 2011

Critical environmental elements for long term preservation of a paper are temperature, humidity, dust, light, contaminants in air, and mold. Especially, temperature and humidity need special care, because they can not only directly degrade paper but also affect the degradation of the other elements. Therefore methods to monitor variation of temperature and relative humidity were studied. One of the methods was to use preservation index for evaluating preservation environment. Since the evaluation for preservation environment of a stack room investigated firstly by D. K. Sebera, PI(preservation index) and TWPI(Time-Weighted Preservation Index) by IPI is made to evaluate relatively preservation environment in a stack room. T. Padfield developed method which could calculate easy PI and TWPI. In this study, the preservation environment of stack rooms for paper storage in NAK(National Archives Korea) was evaluated by PI and TWPI. PI and TWPI of stack rooms for paper storage in NAK maintained good condition but PI depended on season. Then the preservation environment of stack rooms for paper storage in NAK was required to maintain continuously PI and TWPI regardless of season change.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2002.11a
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• pp.514-517
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• 2002

We investigated response characteristics of twisted nematic (TN) cell with different nematic liquid crystals (NLCs) and cell gap d on a rubbed polyimide (PI) surface. High transmittance and fast response time of the TN cell on the rubbed PI surface were achieved by using high birefringence (${\Delta}n$) and low cell gap d. The response time of TN cell on the rubbed PI surface was measured 5.1 ms. The transmittance and response time of the TN cell on the rubbed PI surface decreased with decreasing ${\Delta}nd$.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.66 no.3
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• pp.522-532
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• 2017

In this paper, a new method of SVPWM implementation for 3-Phase 3-Leg 3-Level AC/DC converter known as the Vienna converter is proposed. Also the performances of PI and PR controller used in AC input current controller are compared. To verify the proposed method, PSIM, a power electronics simulation program, is utilized. The performances of the proposed new method and the two existing methods are compared through simulation and experiment. Also PI and PR controller in AC input current controller are compared through 10[kW] Vienna converter system.

• Communications of the Korean Mathematical Society
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• v.34 no.2
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• pp.451-464
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• 2019

In the present paper, we find the sharp bound for the fourth coefficient of starlike functions f which are normalized by f(0) = 0 = f'(0) - 1 and satisfy the following two-sided inequality: $$1+{\frac{{\gamma}-{\pi}}{2\;{\sin}\;{\gamma}}}\;<\;{\Re}\{{\frac{zf^{\prime}(z)}{f(z)}}\}\;<\;1+{\frac{{\gamma}}{2\;{\sin}\;{\gamma}}},\;z{\in}{\mathbb{D}}$$, where ${\mathbb{D}}:=\{z{\in}{\mathbb{C}}:{\left|z\right|}<1\}$ is the unit disk and ${\gamma}$ is a real number such that ${\pi}/2{\leq}{\gamma}<{\pi}$. Moreover, the sharp bound for the fifth coefficient of f defined above with ${\gamma}$ in a subset of [${\pi}/2,{\pi}$) also will be found.

• YAKHAK HOEJI
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• v.27 no.4
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• pp.249-256
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• 1983

When the reaction rate constant k of phospholipase D on liposome was measured by the ANS fluorometry, k of phospholipase D on DMPC liposome which was made of L-$\alpha$-PI, cholesterol and L-$\alpha$-PS decreased than that of phospholipase D on DMPC liposome with cholesterol or with PI and cholesterol. Optimal $Ca^{2+}$ concentration, the most important factor on effect of phospholipase D, also decreased to 1mM, as compared with 10mM and 60mM respectively when cholesterol and PI were added, and cholesterol only was added. The change of cholesterol Mol% had a great influence on k value of phospholipase D. But in case of addition of L-$\alpha$-PS to cholesterol, the influence was relatively diminished.

• Textile Coloration and Finishing
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• v.27 no.4
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• pp.261-269
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• 2015

Two new D-${\pi}$-A dyes were synthesized by the condensation reaction between active methyl and aromatic aldehyde and its biothiol sensing properties in DMSO/water were investigated by UV-vis spectroscopy. Upon addition of $Hg^{2+}$, the solution of D-${\pi}$-A dyes showed color change and the absorption band shows a formation of a dye-$Hg^{2+}$ coordination complex. These dyes exhibited high selectivity for $Hg^{2+}$ as compared with other cations. The dye-$Hg^{2+}$ could be recovered by adding glutathion(GSH). The absorption intensity of dye-$Hg^{2+}$ increased only by the addition of glutathione(GSH). The competition experiments revealed that no obvious interference was observed by performing the titration with the mixture of glutathione(GSH) and other amino acids. The results indicated that these D-${\pi}$-A dyes were highly selective for glutathione(GSH) detection.