• Title/Summary/Keyword: D/L 비

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Xanthine and Aldehyde Oxidase Inhibitory Activities, and Antihyperuricemic Effects of Fermented Smilax china L. Leaf Extracts and Fractions (발효 청미래덩굴잎 용매 추출물 및 분획물의 xanthine 및 aldehyde oxidase 저해활성과 항고요산혈증 효과)

  • Lee, Sang-Il;Lee, Ye-Kyung;Kim, Soon-Dong;Cheng, Jinhua;Yang, Seung Hwan;Suh, Joo-Won
    • Journal of Applied Biological Chemistry
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    • v.57 no.1
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    • pp.53-59
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    • 2014
  • To evaluate the inhibitory effect of xanthine oxidase (XO) and aldehyde oxidase (AO), and antihyperuricemic effect by Aspergillus oryzae fermented Smilax china L. leaf extracts and fractions, we observed extracted yield by each solvent, the content of total polyphenol and total flavonoid (TF), the activities of XO and AO, and serum uric acid level. Extracted yield (g/kg) by 80% ethanol (EtOH) was 13.56, those of n-hexane, dichloromethane (DICM), ethylacetate (EtOAc) and n-butanol fraction (BuOH) were 1.35-3.33. Furthermore, total polyphenol content (mg/g-extract) of EtOAc fraction, BuOH fraction, DICM fraction and EtOH fraction is 478.07-501.26, 259.49-289.02, 165.03-232.27, 134.02-196.54, respectively. Those of fermented EtOAc and DICM fraction was 4.85 and 40.74% higher than that of non-fermented fraction, respectively, while the other fermented fractions were lower than those of non-fermented fractions. And total flavonoid content (mg/g-extract) of EtOAc fraction was higher than those of other fractions. Additionally, TF of fermented EtOAc and BuOH fraction is 10.56 and 60.17% higher, than that of fermented fraction, respectively, although those of the other fermented fractions was lower than that of non-fermented fractions. On the other hand, XO inhibitory activities of all fermented fractions was significantly higher than that of all non-fermented fraction, while those of fermented EtOAc (75.02%) and BuOH fraction (65.59%) was markedly higher than that of non-fermented fraction (39.42 and 5.34%), respectively. In addition, AO inhibitory activities of DICM and EtOAc fraction was 81.82 and 77.93% higher, respectively, than those of the other fractions, and those of fermented fractions as with XO were significantly higher than that of non-fermented fractions. Meanwhile, serum uric acid level (SU) of hyperuricemic control mice (HC, 6.98 mg/dL) was 1.83 folds higher than that of normal control (NC, 3.82 mg/dL). Furthermore, SU in the group treated with EtOAc fraction decreased in a dose dependent manner compared with the allopurinol control group, although those of fermented fractions were significantly lower than those of non-fermented fractions. This study suggests that fermented Smilax china L. leaf extracts may regulate the XO and AO inhibitory activities and antihyperuricemic effect due to aglycone components from glycoside form flavonoids by fermentation of A. oryzae.

Effect of Meals Variety on Obesity Index, Blood Pressure, and Lipid Profiles of Korean Adults (성인의 식사 다양성이 비만도, 혈압 및 혈중 지질패턴에 미치는 영향)

  • Jun, Ye-Sook;Choi, Mi-Kyeong;Bae, Yun-Jung;Sung, Chung-Ja
    • Journal of the Korean Society of Food Culture
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    • v.21 no.2
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    • pp.216-224
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    • 2006
  • This study was conducted to examine the correlation among meals variety, obesity index, blood pressure, and lipid profiles of Korean adults. A total of 308 adults(men 124, women 184) measured the anthropometric characteristics, blood pressure, dietary intake using 24-hour recall method, and serum lipid profile. The average ages of the study subjects were 50.9 yrs in men and 51.4 yrs in women. The average height, weight and BMI were 166.3 cm, 68.4 kg, $24.7\;kg/cm^2$ in men and 154.3 cm, 59.8 kg, $25.0\;kg/cm^2$ in women, respectively. The numbers of food items in meal of men and women were 14.1, 15.9 for breakfast, 15.7, 15.9 for lunch, 14.7, 14.1 for dinner, respectively. The numbers of dish items in meal of men and women were 4.0, 4.3 for breakfast, 4.3, 4.3 for lunch, 4.2, 3.9 for dinner, respectively. The average blood pressure, total cholesterol, triglyceride, HDL-cholesterol, LDL-cholesterol and atherogenic index were 126.6/76.0 mmHg, 181.0 mg/dL, 157.7 mg/dL, 40.9 mg/dL, 108.6 mg/dL, 3.5 in men and 123.2/73.6 mmHg, 185.0 mg/dL, 137.3 mg/dL, 44.8 mg/dL, 112.7 mg/dL, 3.2 in women, respectively. The total cholesterol was negatively correlated to the number of food item for lunch(p<0.05). Therefore, more systematic studies to investigate the meal variety roles of blood lipids in meals of adults were required.

Effects of Glyphosate and 2,4-D Injection on Selective Control of Robinia pseudo-acacia (Glyphosate와 2,4-D의 주사처리(注射處理)가 아카시아 나무의 방제(防除)에 미치는 영향(影響))

  • Kwon, O.W.;Pyon, J.Y.;Lee, J.C.
    • Korean Journal of Weed Science
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    • v.6 no.2
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    • pp.130-133
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    • 1986
  • Glyphosate and 2,4-D were introduced into the vascular systems of Robinia pseudo-acacia L. (3-5cm diameter) with a syringe-type pressure injector in May, 1985. Robinia pseudo-acacia L. were completely controlled by 3 or 6 ml of 3050ppm glyphosate per tree and 6ml of 1000ppm 2,4-D per tree. Herbicidal efficacy was more effective by 6m1 of combined solutions of 1525ppm glyphosate and 500ppm 2,4-D per tree.

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Production of Immunostimulating Polysaccharide in Angelica gigas Nakai SusDension Cell Cultures (참당귀 현탁세포배양에 의한 면역증강성 다당 생산)

  • Kim, Young-Hwa;Kim, Ik-Hwan;Kim, Dong-Il
    • KSBB Journal
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    • v.21 no.5
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    • pp.331-335
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    • 2006
  • Suspension cells of Angelica gigas Nakai were cultivated to produce extracellular polysaccharide(ECP) as immunostimulating agents. Effects of environmental conditions such as sucrose and 2,4-dichlorophenoxyacetic acid(2,4-D) concentrations on the growth and production of ECP were studied using suspension cultures of A. gigas Nakai. Final dry cell weight was increased with an increase of initial sucrose concentration from 30 to 60 g/L. The maximum production of ECP(1.2 g/L) was achieved at an initial sucrose concentration of 50 g/L on day 8. High 2,4-D concentration was effective for ECP production but not for cell growth. In addition, various fungal elicitors were investigated for the enhanced production of ECP in A. gigas suspension cultures. Among the tested fungal elicitors, Verticillium dahliae was the most effective for the production of ECP in A. gigas suspension culture.

Effect of Medicinal Plant Extracts on the Ethanol-Metabolizing Enzyme Activities (약용식물 추출물의 에탄올대사 효소활성에 미치는 영향)

  • Do, Jaeho;Gwak, Jungwon;Lee, Sunjeong;Rho, Jung Jin;Lee, Kwangseung;Kim, Dong Chung
    • Food Engineering Progress
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    • v.21 no.3
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    • pp.286-291
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    • 2017
  • This study was conducted to certify the effect of aqueous extracts from fifty medicinal plants on the activities of alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) in vitro. Each aqueous extract was prepared by combining one-part medicinal plants with twenty-parts distilled water at $80^{\circ}C$ for 8 h. Among the fifty medicinal plants, Allium sativum L. and Cinnamomum cassia Presl were regarded as an effective anti-hangover substance. Allium sativum L. extract increased ALDH activity more than 2 times compared with ADH activity, enhancing the acetaldehyde degradation. Cinnamomum cassia Presl extract dramatically inhibited ADH activity compared with ALDH activity, thus potently decreasing the acetaldehyde formation. ADH and ALDH activities were proportionally inhibited according to the increased concentration of Cinnamomum cassia Presl extract. The aqueous extract of Cinnamomum cassia Presl at a concentration of $45.33{\mu}g/mL$ inhibited ADH activity by 52.8% and ALDH activity by 11.0%.

The Effect of Korean Elderly's Prosthetic Status on Health Related Quality by Using EuroQol-5 Dimension (한국 노인의 보철상태에 따른 건강관련 삶의 질)

  • Park, Jeong-Hye;Lee, Min-Kyung;Lee, Jung-Hwa;Jin, Hye-Jung
    • Journal of dental hygiene science
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    • v.14 no.3
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    • pp.417-423
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    • 2014
  • The aim of this study was to evaluate the relationship between prosthetic status and health related quality of elderly by using EuroQol-5 dimension (EQ-5D) which is a standardized instrument used as a measure of health outcome. Data from 1,179 elderly subjects (over 65 years old) from the fifth Korea National Health and Nutrition Examination Survey were used in our analysis. Oral examination were conducted to obtain wearing prosthetic and needed prosthetic. EQ-5D is a widely used health condition measuring instrument. It consists of the five dimensions: Mobility, Self-care, Usual activities, Pain/discomfort and Anxiety/depression. EQ-5D index is a score calculated out of a weighting system. In this study, the mean score of the EQ-5D index among the elderly was 0.86. For EQ-5D index gender, female showed statistically significantly lower quality of life than male. The related factors EQ-5D index, when the lower demand for fixed prosthodontics and full denture. Wearers in partial and complete denture than non-wearers showed higher EQ-5D index. In order to improve EQ-5D index among the elderly who demand prosthetic status, which has lost its function through providing proper dental prostheses.

A Study on the Hull Form of Fishing Boats around 1900 in South Coast of Korea (한국 남해안의 1900년경 어선의 선형에 관한 연구)

  • 고장권
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.36 no.3
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    • pp.244-248
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    • 2000
  • It was investigated and analized on the construction and hull form for the ordinary fishing boat of south coast in Korea, and then analogized on the shipbuilding technology of fishing boat and fishing type around 1900 by B-spline form parameter method. The results obtained can be summarize as follows : (1) It was known that the boats used in this study have more narrow hull form than that of ancient fishing boats and their hull form was improved around 1900. (2) Keel was composed of bar keel with angle cross section. The stem corner have a material of bar stem and makes a sharp pointed stem. (3) Shell plate was jointed by the rabbetted clinker joint method. (4) It was investigated that anchovy drag net fishing boat has high L/B, L/D, B/D value as compared with drift gill net fishing boat. (5) Two boats have a good stability and particularly anchovy drag net fishing boat have a better stability value in comparison to the drift gill net fishing boat.

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Effects of Different Fiber Content of Rice on Blood Glucose and Triglyceride Levels in Normal Subject (식이섬유함량이 다른 쌀이 정상인의 혈당과 중성지방에 미치는 영향)

  • Lee, Chan;Shin, Jae-Soo
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.31 no.6
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    • pp.1048-1051
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    • 2002
  • This study was conducted to determine the effect of different fiber content of rice on blood levels of glucose insulin and triglyceride in normal subject. Ilpum and Suwon 464, which have different fiber content were used for the test. Two types of rice containing 50 g of carbohydrate were pressure-cooked and fed to ten healthy male volunteers after an overnight fast. After a meal, the 60-min blood glucose levels of Suwon 464 and Ilpum were 90.3$\pm$4.8 mg/dL and 111.6$\pm$2.7 mg/dL, respectively (p<0.01). And the 120-min blood insulin levels of Suwon 464 and IlPum were 2.9$\pm$0.8 mg/dL and 7.7$\pm$1.6 mg/dL, respectively (P<0.05). There was no significant difference in triglyceride level between two rice varieties. The calculated glycemic index (GI) was 64.5% for Suwon 464, suggesting that Suwon 464 high in fiber can be useful in low-GI diets.

An Experimental Study on Stength of Slender Square Tube Columns Filled with High Strength Concrete (고강도콘크리트충전 각형강관장주의 내력에 관한 실험적 연구)

  • Seo, Seong Yeon;Chung, Jin An
    • Journal of Korean Society of Steel Construction
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    • v.14 no.4
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    • pp.471-479
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    • 2002
  • In this paper, 18 square CFT columns filled with high-strength concrete were tested under concentric or eccentric axial loading. Two parameters of the experimental program included the buckling length-section depth ratio ($L_K$/D) and the eccentricity of the appled compressive load (e). In additon, mechanical properties such as the compressive concrete strength and compressive and tensile steel strength were measured and incorporated into the material models for the stress-strain relationships of concrete and steel. This model was used in an elasto-plastic analysis in order to predict the behavior of the slender CFT columns. Observtions of the failure mode during the tests under axial loadig were also presented. The strengths obtained from the analysis. Recommendations for Design, and Constructions of CFT structures were presented, as verified by the experimental results.

Characteristics of the Pressure Instability in a Hydrazine Thruster with Various Length-to-Diameter Ratio of Catalyst-bed (하이드라진 추력기의 촉매대 길이직경비에 따른 압력 불안정 특성)

  • Jung, Hun;Kim, Jong Hyun;Kim, Jeong Soo
    • Journal of the Korean Society of Propulsion Engineers
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    • v.18 no.6
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    • pp.19-26
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    • 2014
  • A ground hot-firing test (HFT) was carried out to make a close examination into the pressure instability for the 70 N-class hydrazine thruster under development. Monopropellant grade hydrazine was adopted as a propellant for the HFT, and catalyst-bed was filled with $Ir/Al_2O_3$ catalyst. In order to investigate the effects of thrust-chamber diameter on combustion stability, evaluation tests for the development models were performed on three kinds of lower thrust chambers having the length-to-diameter ratio (L/D) of 1.03, 1.13, and 1.26. As results, it was found that low frequency instability (~ 50 Hz) was inherent in the models, and in addition, increase of the L/D and decrease of the operating pressure led to an amplification of pressure oscillation in the test condition specified.