• 동의생리병리학회지
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• 제19권2호
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• pp.370-374
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• 2005

Streptococcus mutans (S. mutans) is known as the causative bacterial playing the most important role informing plaque and it is being noticed as major causative bacteria of dental caries. Therefore, development of more effective, substantial and safe preventive agent against dental caries and periodontal disease is honestly required. The present study was designed to investigate the effect of Cyperus rotundus (Cyperaceae) methanol extracts on the growth, acid production, adhesion, and insoluble glucan synthesis of S. mutans. The methanol extract of C. rotundus showed concentration dependent inhibitory activity against the growth and acid production of S. mutans, and produced significant inhibition at the concentration of 0.5, 1, 2 and 4 mg/ml compared to the control group. The extracts markedly inhibited S. mutans adherence to HA treated with saliva, and cell adherence was repressed by more than 50% at the concentration of 0.5 mg/ml and complete inhibition was observed at the concentration of 4 mg/ml. On the activity of glucosyltransferase which synthesizes water insoluble glucan from sucrose, methanol extract of C. rotundus showed more than 10% inhibition over the concentration of 2 mg/ml. Thus, the application of C. rotundus can be considered a useful and a practical method for the prevention of dental caries.

• 한국잡초학회지
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• 제10권2호
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• pp.109-113
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• 1990

Naproanilide의 선택성(選擇性) 작용기작(作用機作)을 구명(究明)하기 위한 실험(實驗)의 일환으로 $^{14}C$-Naproanilide를 공시(供試)하여 벼, 강피, 올미 및 너도방동사니를 대상으로 흡수(吸收) 및 이행실험(移行實驗)을 수행(遂行)하였다. 1. 올미나 너도방동사니는 벼와 강피에 비하여 더 많은 양(量)의 $^{14}C$-Naproanilide를 흡수(吸收)하였으며 경엽부(莖葉部)로의 이행량(移行量)도 많고 이행속도(移行速度)도 빠르게 나타났다. 또한 올미나 너도방동사니는 괴경(塊莖)에도 30~40%의 방사능(放射能)이 존재(存在)해 많은 양(量)의 $^{14}C$-Naproanilide가 괴경(塊莖)으로부터도 흡수(吸收)되는 것으로 사료(思料)된다. 2. $^{14}C$-Naproanilide에 24시간 흡수(吸收)시킨 후 Kasugai 영양액(營養液)에서 재배(栽培)하였을 때 시간이 경과(經過)됨에 따라 식물체내(植物體內)에서 방사능(放射能)은 올미나 너도방동사니의 경우 벼나 강피에 비해 감소(減少)하는 정도는 심하였으나 최종적으로 올미나 너도방동사니의 경엽부(莖葉部)에 더 많은 양(量)의 방사능(放射能)이 존재하였다.

• 한국초지조사료학회지
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• 제22권1호
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• pp.1-8
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• 2002

Chufa(Cyperus esculentus L.)는 고온성 사초과 식물의 일종으로 여름기간에 잘 자란다. 지상부는 주로 잎으로 구성되어 있으며 지하부는 수염뿌리가 뭉쳐 나있고 끝에 괴경이 달린다. 파종 당년에는 출수가 되지 않고 괴경을 많이 생산한다. 번식은 괴경에서 분얼이 많이 나오는 영양번식을 하며 이 분얼이 다발모양(bunch type)의 포기를 형성한다. 성숙기의 초고는 73~75cm 전후이며 7월 중순에 거의 성장이 완료된다. 포기당 분얼의 수는 7월말까지 급격히 증가하고 8월 이후는 서서히 증가하지만 생장이 빈약하였다. 지상부의 최종 생초수량은 40.3ton/ha, 건물수량은 12.2ton/ha이다. 재생력은 생장초기에는 강하지만 2회 예취후는 재생력이 급격히 떨어진다. 무예취구에서 최종 수확기의 포기당 괴경의 수는 722개, 1$m^2$ 당 생체량은 4.2kg, 건물량은 1.9kg이었다. 예취구의 경우 괴경의 생산량은 예취시기가 늦어질수록 감소하였으나 8월 이후에는 이미 괴경생산이 상당히 진행된 것으로 보였다. chufa의 영양생장기 지상부 사료가치는 우수하였으나 생장이 진행될수록 낮아졌다. 최종 수확한 지상부의 조단백질, NDF, ADF, DMD, TDN 함량은 각각 6.1%, 81.5%, 39.8%, 33.2%39.40%, 괴경의 영양성분은 각각 6.0%, 68.3%, 15.5%, 50%, 51.8%였으며, 특히 지방 함량은 16.2%로 높았다.

• 치위생과학회지
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• 제7권3호
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• pp.197-200
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• 2007

본 연구는 생약의 추출분획 용매 중 헥산추출에 따른 우식원인균의 억제효과와 배양시간 경과에 따른 항균력을 시간별로 비교 검토함으로써 치아우식예방제재로서의 가능성을 살펴보고자 헥산 분획에 의한 생약추출물 11종을 대상으로 우식원인균인 S. sobrinus B13를 사용하여 항균활성을 측정하여 다음과 같은 결과를 얻었다. 생약 추출물에 S. sobrinus를 접종한 직후, 6, 12, 24시간 후의 항균효과를 측정해 보았을 때, 단삼이 가장 좋은 항균효과를 나타냈고, 그 다음으로 향부자와 목향, 백출 순으로 나타났다.

• 한국잡초학회지
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• 제18권2호
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• pp.136-145
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• 1998

잔디밭에서 문제잡초로 알려져 있는 향부자의 효과적인 방제를 위한 기초 자료를 제공하고자 향부자의 생육특성, 생장조절제 처리가 맹아 및 생육에 미치는 영향, 제초제의 선발실험, 향부자의 일반성분을 조사하였다. 향부자의 개화는 이식 시기에 관계없이 이식 30일부터 시작되었고 괴경은 기온이 $10^{\circ}C$이하로 내려가면서 형성되기 시작하였다. 생장조절제 BA, ABA, TS-303, PDJ 등의 4종을 향부자 괴경에 처리한 결과 맹아에는 영향을 미치지 않았으며, 이식 60일째부터 경엽에 4회 처리시 4종 공히 신초 수와 지하부 건물중을 다소 증가시켰으나 신초 건물중과 괴경 수에는 영향을 미치지 않았다. Imazaquin 30g ai/10a 처리는 괴경으로부터 다량(multi-shooting)의 신초를 발생시켰으나 pyrazosulfuron-ethyl과 bensulfuron-methyl 처리는 multi-shooting 현상을 보이지 않았다. Pyrazosulfuron-ethyl 10g ai/10a 처리는 향부자의 생육을 90% 가까이 억제하여 bensulfuron-methyl 10g ai/10a 보다 높은 방제율을 보였다. 향부자 성숙한 괴경의 구성성분은 수분 61.83%, 탄수화물 31.60%, 조단백질 4.03%, 조지방 1.57%, 조회분 0.97% 이었다.

• 동의신경정신과학회지
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• 제14권1호
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• pp.59-74
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• 2003

Alzheimer's disease(AD) is a progressive neurodegenerative disease, which is pathologically characterized by neuritic plaques and neurofibrillary tangles associated with the acetylcholinesterase, apolipoprotein E and butylcholinesterase, and by mutations in the presenilin genes PS1 and PS2, and amyloid precursor proteins (APP) overexpression. The present research is to examine the inhibition effect of CPRT on PS-1, PS-2 and APP overexpression by detected to Western blotting. To verify the Effects of CPRT on cognitive deficits further, we tested it on the scopolamine-induced amnesia model of the mice using the Morris water maze tests, and there was ameliorative effects of memory impairment as a protection to scopolamine. CPRT only partially blocked the increase in blood serum level of acetylcholinesterase and Uric acid induced by scopolamine, whereas blood glucose level was shown to attenuate the amnesia induced by scopolamine and inreased extracellular serum level compared with only scopolamine injection. In conclusion, studies of CPRT that has been known as anti-choline and inhibition ablilities of APP overexpression, this could also be used further as a important research data for a preventive and promising symptomatic treatment for Alzheimer's disease.

• 한국의사학회지
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• 제33권1호
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• pp.113-125
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• 2020

This paper analyzes information on Augmented Widen the Core Powder (加味普正散) (AWCP) in the Dr. Kim Young Hoon's medical record database, Cheongang Medical Records. AWCP is a prescription that is not found in the existing medical texts, yet is referred to in Dr. Kim Young Hoon's medical record database. By examining these records, this study shows that the original prescription for AWCP was Decoction for Rectifying the Qi with Cyperus and Kudzu (香葛正氣飮) and that this prescription was deeply related to Rectify the Qi Powder Worth More Than Gold (不換金正氣散) as well as Cyperus and Kudzu Decoction (香葛飮). In addition, AWCP had several names over a long period of time, and its name changed from the Powder of Relieving Lives and Rectifying the Qi (普救正氣散) to AWCP. In particular, this study shows that the term 'gami' (加味 augmented) indicates a change in prescription name, not a change in the composition of the prescription.

• Natural Product Sciences
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• 제17권2호
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• pp.113-116
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• 2011

Arginase competitively inhibits nitric oxide synthase (NOS) via use of the common substrate L-arginine. Arginase II has recently reported as a novel therapeutic target for the treatment of cardiovascular diseases such as atherosclerosis. In our experiment, the EtOH extracts of four-hundreds extracts drugs were investigated for the arginase inhibitory activity. Among them, four extracts exhibited over 50% inhibition of arginase II activity compared to control at a concentration of 150${\mu}g/ml$. In particular, the seed of Arctium lappa, gum-resin of Boswellia carterii, aerial part of Artemisia apiacea and rhizome of Cyperus rotundus inhibited arginase II activity, with $IC_{50}$ values of 118.4, 135.4, 123.9 and 86.7${\mu}g/ml$, respectively. In addition, four plant extracts showed less than 20% inhibition of arginase I activity at 150${\mu}g/ml$. These plants might be the potential candidate materials in the development of the novel atherosclerosis drug.

• 한국작물학회지
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• 제56권1호
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• pp.94-98
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• 2011

Proximate chemical components (protein, oil, carbohydrate, ash, fiber, and starch) were determined from tubers grown in upland and wetland conditions. The contents of crude protein, oil, carbohydrate, and starch were higher in upland condition than in wetland condition. Eight gibberellins were commonly identified and quantified in leaves and tuber of chufa grown in wetland and upland field during growing season. Gibberellin content was always higher specifically in the leaves and tubers grown in wetland condition than in those grown in upland condition. The current knowledge of gibberellin biosynthesis suggests that the two endogenous bio-active gibberellins both $GA_1$ and $GA_4$ are differently metabolized according to cultural conditions. Major gibberellin biosynthesis route is ascertained dominantly the non C-13 hydroxylation pathway leading $GA_4$ in chufa plants.

• 한국습지학회지
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• 제5권2호
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• pp.67-81
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• 2003

Vegetation structure was investigated in the Hwapo wetland around the Nakdong-gang, Gimhae-city, Gyeongsangnam-do, Korea from May to August, 2001. The vegetation type was classified into 18 communities based on the actual vegetation map: Phragmites communis community, Miscanthus sacchariflorus community, Salix nipponica community, Echinochloa crus-galli var. frumentacea community, Zizania latiofolia community, Cyperus amuricus community, Spirodela polyrhiza community, Trapa japonica community, Phragmites communis-Miscanthus sacchariflorus community, Salix nipponiaz-Misaznthus sacchariflorus community, Cyperus amuricus-Acorus calamus var. angustatus community, Salvinia natans community, Hydrilla verticillata-Spirodela polyrhiza community, Persiazria maackiana community, Trapa japonica-Salvinia natans community, Hydrilla verticillata community, Potamogeton crispus community, and Populus deltoides community. Among them, Phragmites communis community was the largest (34.9 ha, 29.53%). The dominant vegetation type was Persiazria hydropiper - Persicaria maackiana community based on the phytosociological method, and it was classified into four subcommunities: Phalaris arundinacea-Salix nipponica subcommunity, Miscanthus sacchariflorus subcommunity, Phragmites communis subcommunity, and Spirodela polyrhiza subcommunity, and Acorus calamus var. angustatus group belongs to Miscanthus sacchariflorus subcommunity.