• Journal of Pharmaceutical Investigation
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• v.31 no.3
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• pp.197-200
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• 2001

Lectin-conjugated ellagitannin (LET), a newly introduced melanoma-specific antitumor agent which has been synthesized by conjugation of wheat germ agglutinin as a lectin with praecoxin A as an ellagitannin, was encapsulated into sterically stabilized liposomes (SSL). Modified Folin phenol method was established for the quantitation of LET contents in liposomal formulations protein employing the standard calibration curve with bovine serum albumin. After removal of phospholipid by organic solvent extraction, which interferes the specific selectivity of the Folin-Ciocalteu reagent with the protein, recovery of LET was $94.5{\pm}2.3%$ and the encapsulation efficiency was revealed as $37.8{\pm}5.9%$ for 2.5 mg/ml LET solution.

• YAKHAK HOEJI
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• v.35 no.1
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• pp.15-21
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• 1991

Quaternary amines which are widely used as medicines are nitrogen compounds. Metanil yellow(MY) and benzalkonium chloride(BKC) were mixed and added to 10ml of the buffer solution and then the solution was shaken for 5 minutes. The maximum absorption wavelength of the reaction product was 402 nm. Dichloromethane was the best extracting solvent among the several organic solvents and the most suitable pH range was 2~8. When the BKC-MY calibration curve was made in the best experimental condition, the Lambert-Beer's law was obeyed in the range of BKC concentration of 2$\times$$10^{-6}$~9$\times$$10^{-6}$M by UV spectrophotometer. This method was possible to determine quaternary ammonium salts in the pharmaceutical preparation.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.5 no.3
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• pp.575-591
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• 2011

We present a novel active contour-based two-pass approach to extract smooth feature regions from a triangular mesh. In the first pass, an active contour formulated in level-set surfaces is devised to extract feature regions with rough boundaries. In the second pass, the rough boundary curve is smoothed by minimizing internal energy, which is derived from its curvature. The separation of the extraction and smoothing process enables us to extract feature regions with smooth boundaries from a triangular mesh without user's initial model. Furthermore, smooth feature curves can also be obtained by skeletonizing the smooth feature regions. We tested our algorithm on facial models and proved its excellence.

• Proceedings of the Korean Society of Agricultural Engineers Conference
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• 2005.10a
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• pp.254-259
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• 2005

The shape of a streamflow hydrograph is very much controlled by the area and depth of snow cover in mountain area. The purpose of this study is to suggest extraction methods for snow cover area and depth using NOAA/AVHRR images in Soyanggang watershed. Snow cover area maps ware derived form channel 1, 3, 4 images of NOAA/AVHRR based on threshold value. In order to extract snow cover depth, snow cover area maps were overlaid daily snow depth data form 7 meteorological observation stations. Snow cover area and depth was mapped for period of Dec. 2002 and Mar. 2003. For evaluating snowmelt changes, depletion curve was created using daily snow cover area in the same period. It is necessary to compare these results with observed data and check the applicability of the suggested method in snowmelt simulation.

• Archives of Pharmacal Research
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• v.13 no.2
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• pp.174-179
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• 1990

Second derivative (D2) spectrometry using ion-pair extraction technique was development for the determination of total glycyrrhetic acid (GA) in Glycyrrhizae Radix, Glycyr-rhizin (G) obtained from Glycyrrhizae Radix was hydrolyzed into GA in 2 N-HCI and methanol (1:1) and extracted from aqueous phase in the form of an ion-pair complex with tetrapentylammonium bromide (TPA) as a counter ion. Maximum D2 amplitude (Z value) was obtained when 1000-fold or greater molar ratio of TPA was used at pH 11. Reaction an effective extraction solvent of the ion-pair complex. The linearity of standard curve of ion-pair GA was obtained in the range of 4.120 $\mu$g/ml as GA. Assayed contents of GA in dry powder by D2 UV spectrometry and HPLC method were 5.31 $\pm$ 0.04% and 5.20 $\pm$ 0.008%, respectively.

• Journal of Computational Design and Engineering
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• v.3 no.2
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• pp.102-111
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• 2016

In this paper, we study the problem of computing smooth feature curves from CAD type point clouds models. The proposed method reconstructs feature curves from the intersections of developable strip pairs which approximate the regions along both sides of the features. The generation of developable surfaces is based on a linear approximation of the given point cloud through a variational shape approximation approach. A line segment sequencing algorithm is proposed for collecting feature line segments into different feature sequences as well as sequential groups of data points. A developable surface approximation procedure is employed to refine incident approximation planes of data points into developable strips. Some experimental results are included to demonstrate the performance of the proposed method.

• The Transactions of the Korean Institute of Electrical Engineers
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• v.43 no.4
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• pp.607-612
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• 1994

The static and dynamic model of IGBT for the SPICE simulation has been successfully developed. The various circuit model parameters are extracted from the I-V and C-V characteristics of IGBT and implemented into our model. The static model of IGBT consists of the MOSFET, bipolar transistor and series resistance. The parameters to be extracted are the threshold voltage of MOSFET, current gain $\beta$ of bipolar transistor, and the series resistance. They can be extracted from the measured I-V characteristics curve. The C-V characteristics between the terminals are very important parameters to determine the turn-on and turn-off waveform. Especially, voltage dependent capacitance are polynomially approximated to obtain the exact turn-on and turn-off waveforms. The SPICE simulation results employing new model agree well with the experimental values.

• Proceedings of the KSRS Conference
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• 2003.11a
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• pp.248-250
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• 2003

An automatic approach and strategy for extracting building information from aerial images using combined image analysis and interpretation techniques is described in this paper. A dense DSM is obtained by stereo image matching. Multi-band classification, DSM, texture segmentation and Normalised Difference Vegetation Index (NDVI) are used to reveal building interest areas. Then, based on the derived approximate building areas, a shape modelling algorithm based on the level set formulation of curve and surface motion has been used to precisely delineate the building boundaries. Data fusion, based on the Dempster-Shafer technique, is used to interpret simultaneously knowledge from several data sources of the same region, to find the intersection of propositions on extracted information derived from several datasets, together with their associated probabilities. A number of test areas, which include buildings with different sizes, shape and roof colour have been investigated. The tests are encouraging and demonstrate that the system is effective for building extraction, and the determination of more accurate elevations of the terrain surface.

• Nuclear Engineering and Technology
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• v.31 no.5
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• pp.445-454
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• 1999

This work describes the adaptation of extractive scintillation by URAE $X^{TM}$ with a photon-electron rejecting alpha liquid scintillation (PERAL $S^{)}$ spectrometer to the analysis of uranium in aqueous samples. The extraction efficiency of the system was evaluated under varing chemical conditions including pH, and sample-cocktail volume ratio. Isotopic information from the (PERAL $S^{)}$ spectrum of natural uranium was obtained using a curve fitting routine. Comparisons of the result with that obtained from alpha spectrometry method using ion implanted silicon detector showed good agreement.t.

• Bulletin of the Korean Chemical Society
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• v.19 no.1
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• pp.45-50
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• 1998

Most organophosphorus pesticides may be metabolized to yield some common phosphates in human or in animals, and these metabolites may be used as the exposure biomarkers to pesticides. In this study, we developed the extraction method of four phosphate metabolites from the spiked human urine in high recovery by the solid phase extraction with a reverse-phase cartridge (cyclohexyl silica) followed by the elution with methanol. The extracted urinary metabolites were derivatized with hexamethyldisilazane/trimethyl-chlorosilane/pyridine (2 : 1 : 10, v/v/v) and identified by gas chromatography/mass spectrometry. Calibration curve obtained from each metabolite standard using by GC/MS/SIM has shown good linearity and detection limits of metabolites were the range of 0.05-0.1 ㎍/㎖ in urine. Phenthoate, one of the organophosphorus pesticides, was orally administrated to rats. Four metabolites were detected in the rat urine. The results of this study may be applied to development of exposure biomarkers for monitoring of environmental pollutants.