• Title/Summary/Keyword: CsA

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Conventional versus Doxorubicin-Eluting Beads Transarterial Chemoembolization for Unresectable Hepatocellular Carcinoma: a Tertiary Medical Centre Experience in Malaysia

  • Rahman, F Abdul;Naidu, J;Ngiu, CS;Yaakob, Y;Mohamed, Z;Othman, H;Jarmin, R;Elias, MH;Hamid, N Abdul;Mokhtar, N Mohd;Ali, RA Raja
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.8
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    • pp.4037-4041
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    • 2016
  • Background: Hepatocellular carcinoma (HCC) is a common cancer that is frequently diagnosed at an advanced stage. Transarterial chemoembolisation (TACE) is an effective palliative treatment for patients who are not eligible for curative treatment. The two main methods for performing TACE are conventional (c-TACE) or with drug eluting beads (DEB-TACE). We sought to compare survival rates and tumour response between patients undergoing c-TACE and DEB-TACE at our centre. Materials and Methods: A retrospective cohort study of patients undergoing either treatment was carried out from January 2009 to December 2014. Tumour response to the procedures was evaluated according to the modified Response Evaluation Criteria in Solid Tumors (mRECIST). Kaplan-Meier analysis was used to assess and compare the overall survival in the two groups. Results: A total of 79 patients were analysed (34 had c-TACE, 45 had DEB-TACE) with a median follow-up of 11.8 months. A total of 20 patients in the c-TACE group (80%) and 12 patients in the DEB-TACE group (44%) died during the follow up period. The median survival durations in the c-TACE and DEB-TACE groups were $4.9{\pm}3.2$ months and $8.3{\pm}2.0$ months respectively (p=0.008). There was no statistically significant difference noted among the two groups with respect to mRECIST criteria. Conclusions: DEB-TACE demonstrated a significant improvement in overall survival rates for patients with unresectable HCC when compared to c-TACE. It is a safe and promising approach and should potentially be considered as a standard of care in the management of unresectable HCC.

An Experimental Study on Compensation Algorithm for Localization using Modified Bilateration Technique and Pyroelectric Sensor in a Ship (변형 이변측위기법과 초전센서를 이용한 선내 위치인식 보정 알고리즘에 관한 실험적 연구)

  • Seong, Ju-Hyeon;Choi, Jae-Hyuk;Kim, Jong-Su;Seo, Dong-Hoan
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.18 no.5
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    • pp.488-495
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    • 2012
  • The real-time indoor location technology using radio waves has been studied in a variety of environments. One of them, a ship which consists of steel structure has high reception rate but causes significant ranging error due to the reflection of radio waves. In order to reduce location measurement errors that occurs in such a environment, this paper, based on CSS of IEEE 802.15.4a, presents compensation algorithm for localization using modified bilateration and pyroelectric sensor in a ship. The proposed system reduces the number of fixed nodes by estimating the appropriate reception distance between mobile node and fixed node through the analysis of CSS characteristic in a narrow passage such as ship corridors. Also, in the corner section which the ranging errors are significantly fluctuated due to the reflection and diffraction of radio waves, we recognize the location by tracking the a moving section using modified bilateration technique and pyroelectric sensor. The experimental results show that the location accuracy and efficiency of the proposed algorithm are improved 86.2 % compared to general method.

Effects of design education program for young Children using 3D printer on creativity improvement (3D 프린터 활용 유아디자인교육 프로그램이 유아의 창의성 및 유용성 증진에 미치는 효과)

  • Jung, Ji-Hyun
    • Journal of Convergence for Information Technology
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    • v.10 no.6
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    • pp.119-127
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    • 2020
  • The purpose of this study is to verify the effect on the creativity and Usability of young Children by applying design education pro young Children gramfor using 3D printer to the kindergarten field and, through the results, to prepare a realistic way to increase the utilization of 3D printer media in infant classrooms. In order to achieve this research purpose, 38 infants aged 5 from G kindergarten located in metropolitan A are divided into each experimental group and comparative group, and from August 2017 to January 2018, data were collected through 15 experiments over a period of about 6 months. As a research tool, in the Korean version of Torrance's Creativity Test, an infant shape test and a usability test scale were used, and the data processing and analysis were conducted through technical statistical methods and covariance analysis. As a result of the study, the program using 3D printer had a statistically significant effect on promoting creativity and Usability of young Children, and in particular, it had a remarkable effect on the elaboration of creativity composition. Based on these results, discussions on the existing Nuri process, which mainly aims to cultivate creative talents, the possibility of connecting 3D printers more widely and the role of teachers were made.

A Study on the Differences in Cost Asymmetry Between Listed Markets and Between Firm Size (상장시장, 기업규모 및 원가의 비대칭성)

  • Choi, Yun-Yee
    • Journal of Convergence for Information Technology
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    • v.10 no.11
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    • pp.302-312
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    • 2020
  • This study examined whether there is a difference in cost asymmetry between a corporate listed on KOSDAQ and a corporate listed on KOSPI, and whether there is a difference in cost asymmetry depending on the size of the listed corporate. In the previous study, cost asymmetry was examined only for listed corporate, but the difference in size between KOSDAQ-listed corporate and KOSPI-listed corporate was not examined. However, according to many studies, since the characteristics of corporate and firm risks are different between corporate listed on KOSPI and corporate listed on KOSDAQ, or even for listed corporate, such an impact may affect the decision-making of internal resource allocation. The analysis was conducted that there would be a difference in the impact. For this study, the results of analyzing the KOSPI and KOSDAQ markets from 2011 to 2019 using the cost behavior model of Anderson et al. (2003), There was a difference in cost behavior in the KOSPI and KOSDAQ markets. Overall, as in previous studies, Cost Stickiness was appeared. but in the case of the KOSPI market, Cost Stickiness was mitigated.It was found that corporate with large corporate size made the decision to dispose of idle resources more clearly when sales decreased. In addition, it was observed that the higher the foreign investor's ownership ratio, the KOSPI market, and the larger the corporate size, the more clearly the Stickiness of cost was mitigated. This study expands research on cost asymmetry and reveals that there is a difference between the KOSPI market and the KOSDAQ market, and between the size of the corporate, and has a differentiation from previous studies.

LOTOS Protocol Conformance Testing for Formal Description Specifications (형식 기술 기법에 의한 LOTOS 프로토콜 적합성 시험)

  • Chin, Byoung-Moon;Kim, Sung-Un;Ryu, Young-Suk
    • The Transactions of the Korea Information Processing Society
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    • v.4 no.7
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    • pp.1821-1841
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    • 1997
  • This paper presents an automated protocol conformance test sequence generation based on formal methods for LOTOS specification by using and applying many existing related algorithms and technique, such as the testing framework, Rural Chinese Postman tour concepts. We use the state-transition graphs obtained from LOTOS specifications by means of the CAESAR tool. This tool compiles a specification written in LOTOS into an extended Petri net, from which a transition graph of a event finite-state machine(EvFSM) including data is generated. A new characterizing sequence(CS), called Unique Event sequence(UE sequence) is defined. An UE sequence for a state is a sequence of accepted gate events that is unique for this state. Some experiences about UE sequence, partial UE sequence and signature are also explained. These sequences are combined with the concept of the Rural Chinese Postman Tour to obtain an optimal test sequence which is a minimum cost tour of the reference transition graph of the EvFSM. This paper also presents a fault coverage estimation experience of an automated method for optimized test sequences generation and the translation of the test sequence obtained by using our tool to TTCN notation are also given. A prototype of the proposed framework has been built with special attention to real application in order to generated the executable test cases in an automatic way. This formal method on conformance testing can be applied to the protocols related to IN, PCS and ATM for the purpose of verifying the correctness of implementation with respect to the given specification.

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Forest Fire Monitoring System Using Satellite (위성활용 산불감시 시스템 구축)

  • Park, Beom-Sun;Cho, In-Je;Lim, Jae-Hwan;Kim, In-Bae
    • Journal of Convergence for Information Technology
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    • v.11 no.11
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    • pp.143-150
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    • 2021
  • It introduces the contents of establishing a geostationary satellite-based forest fire monitoring system that can monitor areas of the Korean Peninsula 24 hours a day for forest fire monitoring, and describes how to establish a forest fire monitoring system and use it in various ways. In order to establish a satellite-utilized forest fire monitoring system, we will describe and draw conclusions on literature research, technical principles, forest fire monitoring means, and satellite forest fire monitoring system. The satellite-utilized forest fire monitoring system can consist of one geostationary satellite equipped with infrared detection optical sensors and a ground processing station that processes data received from satellites to spread surveillance information. Forest fire monitoring satellites are located in the country's geostationary orbit and should be operated 24 hours a day, 365 days a day. Forest fire monitoring technology is an infrared detection technology that can be used in national public interests such as forest fire monitoring and national security. It should be operated 24 hours a day, and to satisfy this, it is efficient to establish a geostationary satellite-based forest fire monitoring satellite system.

Effects of irradiation on the calcific nodule formation in MC3T3-El osteoblastic cell line (MC3T3-El 골모세포주의 석회화결절 형성에 방사선이 미치는 영향)

  • Kang Ki-Hyun;Lee Sang-Rae;Kwon Ki-Jeong;Koh Kwang-Joon
    • Imaging Science in Dentistry
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    • v.35 no.1
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    • pp.1-8
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    • 2005
  • Purpose : To investigate the effects of irradiation on the calcium content and calcific nodule formation in the MC3T3-E1 osteoblastic cell line. Materials and Methods : Cells were irradiated with a single dose of 2,4 and 8 Gy at a dose rate of 5.38 Gy/min using a Cs-137 irradiator. After irradiation, the calcium content and calcific nodule formation were examined on the 1 st, 2nd, 3rd and 4th week. Results : A decreasing dose-dependent tendency of the cell proliferation rate was found in all irradiated groups of this experiment when compared with the unirradiated control group. In accordance with the duration of culture, there was no significant difference in the cell proliferation rate after irradiation of 2 Gy when compared with the unirradiated group, however a decreasing tendency was found in 4 Gy- and 8 Gy-irradiated groups. While an increase in total calcium content after irradiation of 2 Gy was found at week 1, week 2, and week 4, there was a decrease in calcium content at week 1 through 4 in the 8 Gy- irradiated group. Calcific nodule formation was increased in irradiated experimental groups when compared with the unirradiated control group in the 2 Gy-irradiated group, but decreased in the 4 Gy- and 8 Gy-irradiated groups at the same stage. Conclusion : The results showed a mild increasing tendency of the calcific nodule formation after irradiation of 2 Gy. However, a decreased calcific nodule formation in 4 Gy- and 8 Gy-irradiated groups was found. Taken together, the irradiation of 2 Gy mildly activated bone formation, however 4 Gy or 8 Gy suppressed bone formation by decreasing cell numbers in the MC3T3-El osteoblastic cell line.

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The Effects of Perfectionism on Career Decision-making of Self-Efficacy of University Students: The Moderating Effects of Extracurricular Clubactivity Satisfaction (융복합 시대에 대학생의 완벽주의가 진로결정 자기효능감에 미치는 영향: 동아리활동만족도의 매개효과)

  • Kim, Kyung-Suk;Jang, In-Ja
    • Journal of Convergence for Information Technology
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    • v.8 no.1
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    • pp.243-251
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    • 2018
  • This research verified the mediated effect between the level of satisfactory from extracurricular activities and the influence of perfectionism on self efficacy of career decisions. In order to test the theory, a total of 271 students were surveyed from Seoul, Gyeonggi-do, and Chungcheongnam-do. SPSS 21.0 was utilized to study the frequency analysis and technical statistics and a correlation analysis was performed to understand the relationship between major factors. Also, to test the mediated effect we used a recurrent analysis to perform a career analysis. The first result showed adoptable perfectionism affecting the students self efficacy in deciding a career by collecting information on jobs, setting a goal, planning and solving problems. Second, perfectionism influenced the satisfactory level of extracurricular activities. Third, the satisfaction of extracurricular activities acted as a partially mediated effect between the relationship of perfectionism and students self efficacy in deciding their career by collecting information on jobs, setting a goal, planning and solving problems. Therefore, this study indicates to be used as founding material and theoretical implications in order to develop programs to improve self efficacy in career choices for students.

William Faulkner's Requiem for a Nun: Temple's Moral Growth (윌리엄 포크너의 『어느 수녀를 위한 진혼곡』: 템플의 도덕적 성장)

  • Jeong, Hyun-sook
    • Journal of Convergence for Information Technology
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    • v.8 no.1
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    • pp.105-114
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    • 2018
  • The purpose of this study is to reconsider whether Temple in William Faulkner's Requiem for a Nun has grown morally. Temple in Sanctuary, the previous work was raped with a corn cob by Popeye and perjured in the court, resulting in Lee Goodwin's brutal death. Now she is now a mother of two children and a wife of Gowan Stevens, but she cannot get out of the past and tries to run away with Pete, Red's brother, but she was resisted by Nancy Mannigoe, a nanny. Nancy tries to stop Temple sacrificing herself and Temple's baby. When confronting Nancy who accepted her death sentence without hesitation, Temple realized her past guilt which never fades out. A lapse of 20 years between Sanctuary and Requiem provides Temple and author himself opportunities for spiritual and moral growth in spite of painful realization that the past is never past. On the other hand, Faulkner tells the history and the past of Jefferson elaborating the description of the courthouse and the jail. Both are correlated in thematic perspective, the former representing humanity's need for security, the latter the opposite impulse toward aggression and destruction. but together represent the presentness of the past and the fluidity of time.

A Novel Compressed Sensing Technique for Traffic Matrix Estimation of Software Defined Cloud Networks

  • Qazi, Sameer;Atif, Syed Muhammad;Kadri, Muhammad Bilal
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.12 no.10
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    • pp.4678-4702
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    • 2018
  • Traffic Matrix estimation has always caught attention from researchers for better network management and future planning. With the advent of high traffic loads due to Cloud Computing platforms and Software Defined Networking based tunable routing and traffic management algorithms on the Internet, it is more necessary as ever to be able to predict current and future traffic volumes on the network. For large networks such origin-destination traffic prediction problem takes the form of a large under- constrained and under-determined system of equations with a dynamic measurement matrix. Previously, the researchers had relied on the assumption that the measurement (routing) matrix is stationary due to which the schemes are not suitable for modern software defined networks. In this work, we present our Compressed Sensing with Dynamic Model Estimation (CS-DME) architecture suitable for modern software defined networks. Our main contributions are: (1) we formulate an approach in which measurement matrix in the compressed sensing scheme can be accurately and dynamically estimated through a reformulation of the problem based on traffic demands. (2) We show that the problem formulation using a dynamic measurement matrix based on instantaneous traffic demands may be used instead of a stationary binary routing matrix which is more suitable to modern Software Defined Networks that are constantly evolving in terms of routing by inspection of its Eigen Spectrum using two real world datasets. (3) We also show that linking this compressed measurement matrix dynamically with the measured parameters can lead to acceptable estimation of Origin Destination (OD) Traffic flows with marginally poor results with other state-of-art schemes relying on fixed measurement matrices. (4) Furthermore, using this compressed reformulated problem, a new strategy for selection of vantage points for most efficient traffic matrix estimation is also presented through a secondary compression technique based on subset of link measurements. Experimental evaluation of proposed technique using real world datasets Abilene and GEANT shows that the technique is practical to be used in modern software defined networks. Further, the performance of the scheme is compared with recent state of the art techniques proposed in research literature.