• Title/Summary/Keyword: Crossover effect

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DNA 크로스오버가 오리가미 구조물의 강도에 미치는 영향에 대한 유한요소법 기반 민감도 분석

  • Kim, Gyeong-Su
    • Proceeding of EDISON Challenge
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    • 2016.03a
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    • pp.269-269
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    • 2016
  • DNA origami is the most fitting nano-technology for synthesis of complex nano-structures. DNA crossover which ties DNA helices together are the main reason for the stable sustenance of origami structures with respect to other nano-scale structures. The mechanical properties of DNA crossovers have profound connection with structural rigidity, and it is a known fact that the rigidity changes depending on the arrangement of crossovers. It is possible to control the rigidity of origami structures for functionality and furthermore extends the field of DNA origami application. Here, we investigate the effect of crossovers on 2-Dimensional DNA structures varying crossover arrangement by sensitivity analysis based on finite element model. The crossover properties obtained from this analysis are compared with the existing experimental results.

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Assessing Average Bioequivalence for 2×2 Crossover Design with Covariates (공변량을 고려한 2×2 교차설계법에 평균 생물학적 동등성 평가)

  • Jeong, Gyu-Jin;Park, Sang-Gue;Kim, Kwan-Yup
    • The Korean Journal of Applied Statistics
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    • v.24 no.1
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    • pp.161-167
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    • 2011
  • The primary variables are often systematically related to other influences apart from drug effect. For instance, there may be relationships to covariates such as health conditions or prognostic factors. When a $2{\times}2$ crossover experiment for bioequivalence is designed, the statistical adjustment for the influence of covariates should be considered if some covariates influence the drug effect. Statistical inference for assessing average bioequivalence for a $2{\times}2$ crossover design with covariates is given and an illustrated example is presented with discussion.

A Set-theoretic Account of English Crossover Effects

  • Lee, Gunsoo
    • Korean Journal of English Language and Linguistics
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    • v.1 no.1
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    • pp.101-117
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    • 2001
  • In English, whether or not wh-movement creates weak crossover effects depends upon the type of wh-phrases that cross over. A bare interrogative like who shows a typical weak crossover effect whereas which N type (e.g. which girl) and partitive type (e.g. which of these girls) wh-phrases would show mere weaker and weakest crossover effects, respectively. Previous approaches to English crossover phenomena that resort to a binary notion of specificity or D-linking cannot account for the three-way contrast the three different types of wh-phrases show. To overcome this problem, I argue in this paper that specificity should be a non-binary set-theoretic notion and propose the following subset principle and optimal binding relation: Between two lexical nominal expressions A and B, A is regarded as more specific than B iff the denotation of A comes from a more narrowly defined non-singleton set than B. Between two lexical nominal expressions A and B, if A locally binds B, then the non-singleton set from which the denotation of A comes should be a subset of the set from which the denotation of B comes (i.e. B cannot be more specific than A). The smaller the subset (i.e. the wider the specificity gap between binder and binder), the more optimal the local binding relation is. A locally binds B iff A is coindexed with B, and A c-commands B, and there is no such C that does not bind A but binds B. Finally, I show that partitivity functions to carve out a smaller subset and thus make partitive wh-phrases more specific than simple which N type wh-phrases.

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Characterization of Methanol Crossover through Nafion Membranes by Direct Cell Performance Measurement

  • Park, Kyung-Won;Kim, Young-Min;Kwon, Bu-kil;Choi, Jong-Ho;Park, In-Su;Sung, Yung-Eun
    • Journal of the Korean Electrochemical Society
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    • v.5 no.4
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    • pp.226-231
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    • 2002
  • Power densities produced by the permeation of methanol through membranes were directly measured by inserting the membrane in front of anode in a membrane-electrode-assembly of a direct methanol fuel cell (DMFC). The power density was closely related to the loss of power in the DMFC and was strongly affected by temperature. As the cell temperature was increased, the power density resulting from methanol crossover was increased. The increase in methanol crossover had be attributed to diffusion caused or affected by temperature. Methanol crossover a major effect on the performance of a DMFC at a relatively low temperature with $26\%\;loss\;at\;30^{\circ}C$. In order to reduce methanol crossover, a conventional Nafion membrane was modified by the incorporation of Pt or Pd. The reduction in methanol crossover was investigated in these modified membranes by our cell performance measurement. Pt and Pd particles incorporated in the Nafion membranes block methanol pathway and prevent methanol transport through the membranes, which was proved by combining with liquid chromatography.

Comparing the Effects of Aromatherapy on Dysmenorrhea by Research Design (설계유형에 따른 향기요법의 효과)

  • Choi, Eun-Hee;Seo, Ji-Yeong
    • Korean Journal of Adult Nursing
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    • v.22 no.1
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    • pp.31-40
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    • 2010
  • Purpose: The purpose of this study was to examine whether there is difference in the effects of aromatherapy on dysmenorrhea by research design. Methods: Findings from the two different research designs (Nonequivalent control group pretest-posttest [NCG] design vs. two-group crossover design) were compared in regard to the effect of aromatherapy on dysmenorrhea. The subjects of the NCG design and the crossover design were a total of 58 female nursing students. The treatments (aroma essential oil inhalation and carrier oil inhalation) were given using a necklace. The data were analyzed by Fisher's exact test, t-test, Mann-Whitney test, paired t-test, and Shapiro-Wilk test using the SPSS/WIN 12.0 program. The effect size for the two research designs was calculated. Results: In both research designs, the level of dysmenorrhea and menstrual pain after the aroma treatment were not significantly different from those after the placebo treatment. The effect size of the NCG design was higher than that of the crossover design. Conclusion: Aroma inhalation may not be effective in managing dysmenorrhea and menstrual pain. In order to further clarify the efficiency of research design and the effect of aromatherapy on discomfort during menstruation, replication studies are necessary. Future studies need to examine the effects of different research design on non-interval variables.

The Comparison of the Acupuncture-Like Transcutaneous Electrical Nerve Stimulation and Conventional Transcutaneous Electrical Nerve Stimulation in Crossover Effect (침형 경피신경 전기자극법과 전통적인 경피신경 전기자극법의 교차효과 비교)

  • Kwon, Soo-Hyun;Bae, Eun-Young;Shin, Young-Ju;Lee, Jae-Ho
    • Physical Therapy Korea
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    • v.3 no.2
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    • pp.29-35
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    • 1996
  • The purpose of this study was to compare acupuncture-like transcutaneous electrical nerve stimulation(ALTENS) with conventional transcutaneous electrical nerve stimulation(C-TENS) for crossover effect in healthy subjects. Forty subjects recieved ALTENS(20 persons), C-TENS(20 persons) to one upper extremity. Each technic was applied to the motor point of the wrist extensor muscle group for twenty-minutes. With the subject placed in supine the technics were applied at 80 Hz, 2-10 mA(ALTENS) and 10 Hz, 4-12 mA(C-TENS). Results revealed: (1) a significant difference between the pretreatment and posttreatment in each group(p<.05) (2) no significant difference between ALTENS and C-TENS(p>.05). In conclusion, there was no difference between ALTENS and C-TENS for crossover effect.

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Effect of Temperature on Electrochemical Degradation of Membrane in PEMFC (PEMFC 고분자 막의 전기화학적 열화에 미치는 온도의 영향)

  • Lee, Ho;Kim, Taehee;Son, Ik Jae;Lee, Jong Hyun;Lim, Tae Won;Park, Kwonpil
    • Korean Chemical Engineering Research
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    • v.47 no.4
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    • pp.441-445
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    • 2009
  • Effect of temperature on membrane degradation in PEMFCs was studied. After cell operation at different temperatures($60{\sim}90^{\circ}C$) under accelerating degradation conditions(OCV, anode dry, cathode RH 65%) for 144 h, cell performance decreased from 12 to 35%. The results of FER in effluent water showed that this decrease in cell performance was caused by membrane degradation by the attack of $H_2O_2$ or oxygen radicals(${\cdot}OH$, $HO_2{\cdot}$) and that resulted in increase in gas crossover for radical formation. Radical formation on the electrode was confirmed by ESR. Activation energy of 66.2 kJ/mol was obtained by Arrhenius plot used to analyze the effect of temperature on membrane degradation. Increase of cell temperature enhanced gas crossover rate, radical formation rate and membrane degradation rate.

The Effect of Crossover Musical Activities: Applying the Traditional Korean Jang-dan on the Multicultural Perception of Young Children (국악장단을 적용한 크로스오버 음악활동이 유아의 다문화 인식에 미치는 영향)

  • Hong, Khil Hoe;Youn, Hea Ja
    • Korean Journal of Childcare and Education
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    • v.10 no.2
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    • pp.21-41
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    • 2014
  • The purpose of his study was to explore the effect of crossover musical activities applying the traditional Korean Jang-dan on the multicultural perception of young children. The subjects of this study were one class of 21 5-year-old children(experimental group) in J kindergarten and two classes of 5-year-old children (20 children in comparative group and 20 children in control group) in S kindergarten located in Y city, totaling 61 children (31 male children and 30 female children). Twenty sessions of Crossover musical activities applying the traditional Korean Jang-dan (rhythmic patterns) developed by the author were applied to the experimental group, musical activities focusing on traditional Korean music to the comparative group and musical classes from Nuri curriculum for 5-year-olds to the control group, respectively. The result of this study showed the following, among the sub-factors of multi-cultural perception, the scores of post-cultural openness and post-cultural acceptability showed a significantly higher level in statistical terms in the experimental group, for which crossover musical activities applying the traditional Korean Jang-dan were conducted, than those in the comparative group and the control group. The comparative group which participated in musical activities of traditional Korean music exhibited a significantly higher level of post-cultural respectfulness statistically (than other groups). The result of this study implies that crossover musical activities applying the traditional Korean Jang-dan have the effect of enhancing the perception of cultural openness and cultural acceptability which are the sub-factors of young children's multi-cultural perception.

Derivation of error sum of squares of two stage nested designs and its application (이단계 지분계획법의 오차제곱합 유도와 그 활용)

  • Kim, Daehak
    • Journal of the Korean Data and Information Science Society
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    • v.24 no.6
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    • pp.1439-1448
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    • 2013
  • The analysis of variance for randomized block design or two way classification data is well known. In this paper, particularly, we considered two stage nested design in which the levels of one factor is not identical for different levels of another factor. We investigate the structural properties of two stage nested design and the properties of error sum of squares for random effect model. For the application of two way nested design, we consider two-period crossover design which is used commonly for the equivalence test to bio-similar product. The confidence interval estimation of the difference of two population means in the crossover design is discussed based on statistical package SPSS.

Effect of curing temperature and blast furnace slag concrete on concrete strength development (양생온도가 고로슬래그 콘크리트의 강도발현에 미치는 영향분석)

  • Lee, Kyu-Dong;Jun, Myeong-Il;Lee, Chang-Soo;Kim, Dong-Sik
    • Journal of the Society of Disaster Information
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    • v.2 no.1
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    • pp.129-137
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    • 2006
  • The present work is attempt to evaluate the temperature dependence of blast furnace slag concrete(BFSC) based on the concrete strength cured with different curing temperatures and ages. A equivalent substitution index(ESI) was induced to explain temperature dependence of concrete quantitatively as well as concrete strength. The results from compressive strength showed substantial crossover effect. which is the phenomenon that the compressive strength cured at low temperature becomes stronger than the one cured at high temperature. The crossover effect found more definitely on BFSC than plain concrete.. The ESI became 1.1 and 1.0 for the BFSC cured at $20^{\circ}C$ and $30^{\circ}C$ after age of 56 days, respectively. Which means that the contribution to strength development of blast furnace slag per unit mass is stronger than that of the Portland cement. It was considered therefore that the optimum curing temperature for BFSC is $20^{\circ}C$.

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