• Molecules and Cells
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• v.44 no.5
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• pp.318-327
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• 2021

CD4+ T helper (Th) cells play a crucial role in the modulation of innate and adaptive immune responses through the differentiation of Th precursor cells into several subsets, including Th1, Th2, Th17, and regulatory T (Treg) cells. Effector Th and Treg cells are distinguished by the production of signature cytokines and are important for eliminating intracellular and extracellular pathogens and maintaining immune homeostasis. Stimulation of naive Th cells by T cell receptor and specific cytokines activates master transcription factors and induces lineage specification during the differentiation of Th cells. The master transcription factors directly activate the transcription of signature cytokine genes and also undergo post-translational modifications to fine-tune cytokine production and maintain immune balance through cross-regulation with each other. This review highlights the post-translational modifications of master transcription factors that control the differentiation of effector Th and Treg cells and provides additional insights on the immune regulation mediated by protein argininemodifying enzymes in effector Th cells.

• The Journal of the Acoustical Society of Korea
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• v.28 no.8
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• pp.755-760
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• 2009

In this paper, we apply a reverberation suppression method using difference of singular values to improve the short-distance underwater obstacle detection probability in reverberation environment induced by a linear frequency modulation signal. The reverberation suppression method using difference of singular values suppresses LFM reverberation based on subtracting the singular values for a reference beam, assumed to contain only the reverberation, from those for the current beam of interest, assumed to contain the reverberation and target echo. For the validation, the reverberation suppression method using difference of singular values is applied to real oceanic data, which are acquired using the cross type array.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.21 no.9
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• pp.995-1004
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• 2010

In the channel-varying environment, it is very important to estimate the signal to noise ratio(SNR) of received signal and to transmit the signal effectively for the modern communication system. The performance of existing non-data-aided (NDA) SNR estimation methods are substantially degraded for high level modulation scheme such as M-ary APSK or QAM. In this paper, we propose a SNR estimation method which uses zero point auto-correlation of received signal per block and auto-/cross- correlation of decision feedback signal in OFDM system. Proposed method can be studied into two Types; Type 1 can estimate SNR by zero point auto-correlation of decision feedback signal based on the second moment property. Type 2 uses both zero point auto-correlation and cross-correlation based on the fourth moment property. In block-by-block reception of OFDM system, these two SNR estimation methods can be possible for the practical implementation due to correlation based the estimation method and they show more stable estimation performance than the previous SNR estimation methods. Also, we mathematically derive the SNR estimation expression according to computational difference of auto-/cross-correlation. Finally, Monte Carlo simulations are used to verify the proposed method.

• The Journal of Korean Academy of Sensory Integration
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• v.21 no.3
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• pp.54-64
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• 2023

Objective : This study aims to ascertain the effect of oral activity and sensory integration therapy on drool and play using oral toys in children with developmental delays. Methods : The participants of the study were two children (2 years and 8 months) experiencing developmental delays with sensory modulation problems in their oral sensory faculties. The research design was multi-baseline design cross-subjects among single-subject research ABA. Target behaviors were measured by drooling and interest and concentration in play using oral toys through the Goal Attachment Scale (GAS). In the 10 sessions that the children underwent during the intervention period (B), oral activity and proprioception-vestibular sensory integration therapy were applied. Results : The GAS of drooling improved from 0.25 for child A and -0.5 for child B during the baseline to 1.88 for child A and 1.4 for child B during the intervention period. The follow-up was 3 for both child A and child B. Meanwhile, the GAS of play during the baseline was -0.75 for child A and 0.75 for child B, and 1.9 for child A and 1.1 for child B during the intervention period. The follow-up was 1.33 for child A and 2 for child B. Conclusion : Oral activity and proprioceptive-vestibular sensory integration therapy are effective in drooling and playing with oral toys in children with sensory modulation problems in their oral sensory faculties.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.32 no.2A
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• pp.188-194
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• 2007

In order to become ubiquitous world, the compatibility of wireless machines has become the significant characteristic of a communication terminal. Thus, SDR is the most necessary technology and standard. However, among the environment which has different communication protocol, it's difficult to make a terminal with only hardware using ASIC or SoC. This paper suggests the processor that can accelerate several communication protocol. It can be connected with main-processor, and it is specialized PHY layer of network The C-program that is modeled with the wireless protocol IEEE802.11a and IEEE802.11b which are based on widely used modulation way; OFDM and CDM is compiled with ARM cross compiler and done simulation and profiling with Simplescalar-Arm version. The result of profiling, most operations were Viterbi operations and complex floating point operations. According to this result we suggested a co-processor which can accelerate Viterbi operations and complex floating point operations and added instructions. These instructions are simulated with Simplescalar-Arm version. The result of this simulation, comparing with computing only one ARM core, the operations of Viterbi improved as fast as 4.5 times. And the operations of complex floating point improved as fast as twice. The operations of IEEE802.11a are 3 times faster, and the operations of IEEE802.11b are 1.5 times faster.

• Journal of the Institute of Electronics and Information Engineers
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• v.52 no.5
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• pp.3-9
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• 2015

The wireless communication system adopts an appropriate retransmission scheme on each system protocol layer to improve reliability of data transmission. In each system protocol layer, the retransmission scheme operates in independently other layers and operates based on the parameters without reference to end-to-end performance of wireless communication system. For this reason, it is difficult to design the optimal system parameters that satisfy the QoS requirements for each service class. Thus, the performance analysis of wireless communication system is needed to design the optimal system parameters according to the end-to-end QoS requirements for each service class. In this paper, we derive the mathematical model to formulate the end-to-end performance of wireless communication system. We also evaluate the performance at the MAC and transport layers in terms of average spectral efficiency and average transmission delay. Based on the results of performance evaluations, we design the optimal system parameters according to the QoS requirements of service classes. From the results, the HARQ combined with AMC is appropriate for the delay-sensitive service and the ARQ combined with AMC is appropriate for a service that is insensitive to transmission delay. Also, the TCP can be applied for the delay-insensitive service only.

• 전자공학회논문지 IE
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• v.44 no.3
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• pp.23-34
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• 2007

For an effective phase multiplexing in a volume holographic system, four types of phase code, pseudo random code(PSC), Hadamard matrix(HAM), pure random code(PRC), equivalent random code(ERC), used as reference beams are generated. In case of $32{\times}32$ address beam, a phase error with 0%, 5%, 10%, 15%, 20%, and 25% error rate, is purposely added to the real phase values in order to consider the practical SLM's nonlinear characteristics of phase modulation in computer simulation. Crosstalks and SNRs(signal-to-ratio) are comparatively analyzed for these phase codes by the auto-correlation and cross-correlation. PSC has the lowest cross-correlation mean value of 0.067 among four types of phase code, which means the SNR of the pseudo random phase code is higher than other phase codes. Also, the standard deviation of the pseudo random phase code indicating the degree of recalled data degradation is the lowest value of 0.0113. In order to analyze the affect by variation of pixel size, simulation is carried out by same method for the case of $32{\times}32$, $64{\times}64$, $128{\times}128$, $256{\times}256$ address beams.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.28 no.1C
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• pp.1-8
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• 2003

In this paper, performance of the CPC(complex phase code) which is recently proposed as a practical phase encoding method for phase-code multiplexes holographic memory system is comparatively analyzed with those of the conventional phase codes such as PR(pure random code), RCE(random code with equality), WHM(Walsh Hadamard Matrix). In computer simulation, the size of an address bean is fixed at 32$\times$32 pixels and 0%-25% phase-error ratio in a pixel are intentionally added to the real phase values to consider the nonlinear phase-modulation characteristics of the practical spatial light modulator. From comparative analysis of crosstalks and signal-to-noise ratios for these phase codes by calculating auto-correlation and cross-correlation, it is found that the CPC have the lowest cross-correlation mean value of 0.021, the lowest standard deviation of 0.0113 and the highest signal-to-noise ratio(SNR) of 27.4 among the four types of phase code. In addition, from the calculation of the number of all possible address beams for these four types of phase code as the size of the address beam is fixed to 3232 pixels, the CPC is found to have 6.334$\times$10$^{49}$ address beams, which are relatively higher number than that of the conventional phase codes.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.16 no.6
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• pp.125-133
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• 2016

As one of solutions to pursue the efficient use of spectrum resource, we proposed the methodology for the co-channel multi-site radar operations with the synchronous GPS clock. The proposed algorithm, based on a quasi orthogonal property, find a candidate set of the time shifted linear frequency modulation(TSLFM) signals with the minimum acceptable level of the correlation among selected TSLFM signals. To check suggested algorithm, numerical analysis for several radars operating in the same channel with a sawtooth waveform has been performed by using range-Doppler processing for the given system parameters, and computational results are presented and examined in terms of range profile and doppler shift for a targets with velocity and distance. Simulated results have a good agreement with assumed target distance and its velocity, within the error of resolution.

• Journal of the Korean Geographical Society
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• v.32 no.4
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• pp.551-556
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• 1997

Defining sustainable development as the challenge of continuously balanving economic, social and ecological values, a European research project sought lessons from experiences of a forty year period to frame criteria of appropriate scale for contextually-sensitive environmental policy. A network of case studies conducted by partner teams in Gemany, lreland, the Netherlands and Sweden examined changes of scale in the territorial, functional and socio-political contexts of life and landscape between 1950-1990. Themes central to the project included landscape transformations, tensions among area-and sector-based ways of life [genres de vie], and changing horizons of discretionary reach. With illustrations drawn mainly from the lrish case studies in Tipperary, this lecture outlines some regional differences in response to externa-policy and market-driven-influences. Implications for cross-cultural research and the framing of contextually-sensitive environmental policy are outlined, and suggestions made for their modulation through European Union, national, regional, and local levels.