• 한국보건간호학회지
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• 제17권1호
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• pp.122-131
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• 2003

This study was designed to provide the base of nursing intervention that could help apheresis blood-donors to promote self-efficacy effectively by analyzing critical factors that influence on this. The subjects recruited for the research were 468 persons who participated in platelet donation at a university hospital apheresis unit in Seoul. The data for this study were collected between May and June, 2002 using questionnaires. Data were analyzed by t-test, ANOVA, Scheffe test, and stepwise multiple regression. The results were as follows. 1. The mean self-efficacy score on the questions related to blood donation was $32.9\pm5.1$, indicating that blood donors have above the mean level of self-efficacy related to blood donation. 2. The self-efficacy score was significantly higher for the group of persons who have more than 5 times of experiences in blood donation than others who have only one experience. 3. The critical factors that influence self-efficacy related to donation were the marital status, educational level. and previous experiences of whole blood donation, while the critical factor that influence on general self-efficacy was previous experiences of whole blood donation. Therefore, it is necessary to establish more effective and organized nursing intervention strategies that can promote the self-efficacy of apheresis blood-donors.

• Spatial Information Research
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• 제14권4호
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• pp.363-377
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• 2006

본 연구에서는 개정범용토양유실공식(RUSLE: Revised Universal Soil Loss Equation)을 이용하여 미국 South Carolina 주 Congaree 유역에 대한 평균 연간 토양 유실량을 산출 하였으며 비점오염원 토양 유실 민감지역을 추출하였다. 평균 연간 토양 유실량은 강우-유출 침식성 인자, 토양침식성 인자, 지면특성 인자, 식생피복 인자, 그리고 토양보존 인자의 곱으로 계산할 수 있으며, 토양 유실 민감지역은 토양 유실량이 토양침식 허용량을 초과하는 지역으로 추출할 수 있다. 연구 결과, 전체 면적의 10% 이상의 면적이 비점오염원 토양 유실 민감 지역으로 확인되었으며, Congaree 유역의 7개 소유역중 Congaree Creek, Gills Creek 소유역의 도심지역과 Cedar Creek 소유역의 농업지역에서 가장 심각한 토양 유실의 위험이 나타났다. 관심 지역의 인위적, 자연적 변화가 토양 유실에 가져오는 영향을 살펴보기 위한 시범 모형으로서, 개정범용토양유실공식에 기초한 내장형 모형이 Visual Basic for Applications (VBA)를 이용하여 ESRI사의 ArcGIS ArcMap 9.0에서 사용할 수 있도록 개발되었다. 이 내장형 모형에서 사용자는 각 소유역의 토지 피복, 식생 유형, 지표 식생 유형, 경사, 작물 유형, 경작 방식 등을 변경시킴으로써 C, LS, P 인자를 변화시킬 수 있으며, 계산된 평균 연간 토양 유실량과 민감 지역을 현재 상태의 값들과 비교하여 앞으로의 토양유실 관리를 위한 주요 정보로 사용할 수 있다.

• 조명전기설비학회논문지
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• 제20권10호
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• pp.41-46
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• 2006

상업용으로 계통에 연계되어 운전되는 대부분의 풍력발전기는 유도발전기가 주로 사용되고 있으며 동기발전기와 다른 양상을 보이고 있어 계통에서의 사고발생 후 정상상태로 복귀할 수 있는 최대의 시간(임계 제거시간)을 이용하여 과도상태를 해석하고 있다. 본 연구에서는 풍력 발전시스템이 연계된 계통에 대해 임계 제거시간에 미치는 요인을 분석하였으며 계통해석 프로그램인 Digsilent Power Factory를 이용하였다. 임계 제거시간에 미치는 요인으로는 연계되는 계통의 단락용량(단락전류). 풍력발전 용량, 풍력발전기 역률, 풍력 발전시스템과 연계되는 계통사이의 전용선 길이, 부하 용량이나 역률 등이 있으며 이들의 변화에 대한 임계 제거시간의 영향을 분석하였다.

• 한국산학기술학회논문지
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• 제10권10호
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• pp.2810-2818
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• 2009

본 연구는 화강풍화토로 구성된 절토사면에서 얕은파괴의 특성을 규명하고자 우리나라의 강우특성에 따른 한계투수계수를 산정하고, 국내에 분포하는 화강풍화토의 대표적 물성을 기준으로 절토사면의 파괴면까지의 수평거리, 사면의 경사각, 사면높이 그리고 강우로 인한 포화깊이 등에 따른 안정해석을 수행하여 그 결과를 분석하였다. 한계투수계수를 분석한 결과 국내의 지역별 강우특성을 고려한 최대 한계투수계수가 $7.16{\times}10^{-4}cm/sec$의 값으로 나타났다. 최대 한계투수계수 이하의 값을 갖는 국내의 화강풍화토로 구성된 절토사면에서 한계강우강도 이하의 강우가 최소 강우지속시간보다 오랫동안 지속될 때에는 포화깊이에 따른 얕은파괴의 검토가 고려되어져야 할 것으로 판단되었다. 또한, 가상파괴면이 발생하는 수평거리, 포화깊이, 강도정수 변화에 따른 사면안전율의 변화관계를 통해 절토사면의 얕은파괴 특성을 파악 할 수 있었다.

• Molecules and Cells
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• 제45권6호
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• pp.413-424
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• 2022

Suppressor of mothers against decapentaplegic homolog (SMAD) 4 is a pluripotent signaling mediator that regulates myriad cellular functions, including cell growth, cell division, angiogenesis, apoptosis, cell invasion, and metastasis, through transforming growth factor β (TGF-β)-dependent and -independent pathways. SMAD4 is a critical modulator in signal transduction and functions primarily as a transcription factor or cofactor. Apart from being a DNA-binding factor, the additional SMAD4 mechanisms in tumor suppression remain elusive. We previously identified methyl malonyl aciduria cobalamin deficiency B type (MMAB) as a critical SMAD4 binding protein using a proto array analysis. This study confirmed the interaction between SMAD4 and MMAB using bimolecular fluorescence complementation (BiFC) assay, proximity ligation assay (PLA), and conventional immunoprecipitation. We found that transient SMAD4 overexpression down-regulates MMAB expression via a proteasome-dependent pathway. SMAD4-MMAB interaction was independent of TGF-β signaling. Finally, we determined the effect of MMAB downregulation on cancer cells. siRNA-mediated knockdown of MMAB affected cancer cell metabolism in HeLa cells by decreasing ATP production and glucose consumption as well as inducing apoptosis. These findings suggest that SMAD4 controls cancer cell metabolism by regulating MMAB.

• 대한산업공학회지
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• 제29권2호
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• pp.179-189
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• 2003

Gate poly-silicon critical dimension is a prime characteristic of a metal-oxide-semiconductor field effect transistor. It is important to achieve the uniformity of gate poly-silicon critical dimension in order that a semiconductor device has acceptable electrical test characteristics as well as a semiconductor wafer fabrication process has a competitive net-die-per-wafer yield. However, on gate poly-silicon critical dimension, the complexity associated with a semiconductor wafer fabrication process entails hierarchical variance components according to run-to-run, wafer-to-wafer and even die-to-die production unit changes. Specifically, estimates of the hierarchical variance components are required not only for disclosing dominant sources of the variation but also for testing the wafer-level uniformity. In this paper, two experimental designs, a two-stage nested design and a randomized complete block design are considered in order to estimate the hierarchical variance components. Since gate poly-silicon critical dimensions are collected from fixed die positions within wafers, a factor representing die positions can be regarded as fixed in linear statistical models for the designs. In this context, the two-stage nested design also checks the wafer-level uniformity taking all sampled runs into account. In more detail, using variance estimates derived from randomized complete block designs, Duncan's multiple range test examines the wafer-level uniformity for each run. Consequently, a framework presented in this study could provide guidelines to practitioners on estimating the hierarchical variance components and testing the wafer-level uniformity in parallel for any characteristics concerned in semiconductor wafer fabrication processes. Statistical analysis is illustrated for an experimental dataset from a real pilot semiconductor wafer fabrication process.

• Geomechanics and Engineering
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• 제27권6호
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• pp.605-614
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• 2021

Water inrush from fault is one of the most severe hazards during tunnel excavation. However, the traditional evaluation methods are deficient in both quantitative evaluation and uncertainty handling. In this paper, a comprehensive methodology method combined intuitionistic fuzzy AHP with a Bayesian network for the risk assessment of water inrush from fault in the subsea tunnel was proposed. Through the intuitionistic fuzzy analytic hierarchy process to replace the traditional expert scoring method to determine the prior probability of the node in the Bayesian network. After the field data is normalized, it is classified according to the data range. Then, using obtained results into the Bayesian network, conduct a risk assessment with field data which have processed of water inrush disaster on the tunnel. Simultaneously, a sensitivity analysis technique was utilized to investigate each factor's contribution rate to determine the most critical factor affecting tunnel water inrush risk. Taking Qingdao Kiaochow Bay Tunnel as an example, by predictive analysis of fifteen fault zones, thirteen of them are consistent with the actual situation which shows that the IFAHP-Bayesian Network method is feasible and applicable. Through sensitivity analysis, it is shown that the Fissure development and Apparent resistivity are more critical comparing than other factor especially the Permeability coefficient and Fault dip. The method can provide planners and engineers with adequate decision-making support, which is vital to prevent and control tunnel water inrush.

• 지질공학
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• 제31권4호
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• pp.463-478
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• 2021

The subjects of the study are the sedimentary rock slope of the Mesozoic Gyeongsang Supergroup, which has a high risk of failure. The orientation of the slope-face represents a variety of changing characteristics. The rocks of the slope shall be sandstone, siltstone and dacite, and discontinuities shall develop beddings, shear joints, extension joints, and dacite dyke boundary planes. The type and scale of failure varies depending on the type of rock and the strike/dip of the discontinuities, but the toppling failure prevails. Based on the face-mapping data, SMR, physical and mechanical testing of rocks, analysis and review of the stereonet projections and the critical equilibrium analysis, all four representative sections required a countermeasure method because the acceptable safety factor during dry and rainy seasons were far below Fs = 1.5 and Fs = 1.2. After applying the countermeasure method, both the dry and wet conditions of the slope exceeded the allowable safety factor. In particular, the face-mapping data of the slope-face, the geological cross-sections of several representative sections perpendicular to the slope-face, and the critical equilibrium analysis and the presentation of countermeasure methods that have been reviewed based on them are expected to be reasonable tools for the slope stability. In addition, it will be possible to use it as basic data for performance evaluation for slope maintenance.

• 한국군사과학기술학회지
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• 제21권2호
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• pp.217-224
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• 2018

The purpose of this study is to evaluate the future potential value of CTE(Critical Technology Element)s that are evaluated to be low in TRA(Technology Readiness Assesment) and to present investment prioritization technologies in defense R&D(Research and Development) based on them. To do this, we used the DEA(Data Envelopment Analysis) method, which is useful in evaluating the efficiency of the organization. Specifically, we suggest a systematic framework to evaluate the future value of CTEs by setting the CTEs derived from the TRA process to DMU(Decision Making Unit)s, the cost and time required to develop each CTE as the input factor of the DEA and the effects of the development of each CTE as the output factor of the DEA respectively. We also conducted an illustrative case study on radar technologies to demonstrate the usefulness of the proposed approach.

• Journal of Construction Engineering and Project Management
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• 제6권4호
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• pp.24-34
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• 2016

Disputes seem to be synonymous with large-scale construction projects in Ethiopia. The purpose of this study is to determine the factors responsible for impacting the performance of Ethiopian public construction projects. To this end, 35 success and failure attributes responsible for impacting the performance of the projects were identified and presented to Ethiopian construction professionals in the form of a structured questionnaire, and responses were collected. The factor analysis conducted on the success and failure attributes influencing no-dispute performance separately resulted in six success factors and five failure factors. Further analysis using stepwise multiple regression indicates that owner competence and interaction among project participants have a positive impact on no-dispute performance. However, conflict among project participants has a negative impact on the no-dispute performance of Ethiopian public construction projects. Although Ethiopia-specific, the results reflect construction management problems common to both developed and developing countries. The findings are expected to help researchers and practitioners gain a better understanding of critical success and failure factors and to help them take proactive measures to avoid disputes in public construction projects.