• Advances in nano research
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• v.3 no.3
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• pp.143-168
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• 2015

Initiation of crack and its growth simulation requires accurate model of traction - separation law. Accurate modeling of traction-separation law remains always a great challenge. Atomistic simulations based prediction has great potential in arriving at accurate traction-separation law. The present paper is aimed at establishing a method to address the above problem. A method for traction-separation law prediction via utilizing atomistic simulations data has been proposed. In this direction, firstly, a simpler approach of common neighbor analysis (CNA) for the prediction of crack growth has been proposed and results have been compared with previously used approach of threshold potential energy. Next, a scheme for prediction of crack speed has been demonstrated based on the stable crack growth criteria. Also, an algorithm has been proposed that utilizes a variable relaxation time period for the computation of crack growth, accurate stress behavior, and traction-separation atomistic law. An understanding has been established for the generation of smoother traction-separation law (including the effect of free surface) from a huge amount of raw atomistic data. A new curve fit has also been proposed for predicting traction-separation data generated from the molecular dynamics simulations. The proposed traction-separation law has also been compared with the polynomial and exponential model used earlier for the prediction of traction-separation law for the bulk materials.

• Nuclear Engineering and Technology
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• v.53 no.3
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• pp.911-919
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• 2021

In this paper, the design stress intensity values for the plate-type fuel assembly for research reactor are presented. Through a tensile test, the material properties of the cladding (aluminum alloy 6061) and structural material (aluminum alloy 6061-T6), in this case the yield and ultimate tensile strengths, Young's modulus and the elongation, are measured with the temperatures. The empirical equations of the material properties with respect to the temperature are presented. The cladding undergoes several heat treatments and hardening processes during the fabrication process. Cladding strengths are reduced compared to those of the raw material during annealing. Up to a temperature of 150 ℃, the strengths of the cladding do not significantly decrease due to the dislocations generated from the cold work. However, over 150 ℃, the mechanical strengths begin to decrease, mainly due to recrystallization, dislocation recovery and precipitate growth. Taking into account the uncertainty of the 95% probability and 95% confidence level, the design stress intensities of the cladding and structural materials are established. The presented design stress intensity values become the basis of the stress design criteria for a safety analysis of plate-type fuels.

• Journal of the Korean Society of International Agriculture
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• v.30 no.4
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• pp.257-268
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• 2018

Recently, the international standardization of ISO in the field of Oriental Herbal Medicine has been progressing rapidly under the direction of China's promotion. China's intention to promote international standardization is to extend its influence to the world and beyond the domestic market. The Oriental medicine system in East Asia has similar roots in academic terms, but the medicines that can be supplied and received in each country are different and have developed independently. The international standardization of medicinal herbs is expected to function in a direction that weakens such differentiation and independence. From a commercial point of view, international standardization is no different from creating evaluation criteria for oriental medicinal products, and it is expected that its potential impact on domestic and overseas markets and producers will be large. In particular, the international standardization centered on China can lead to favorable evaluation criteria for China, which may further negatively affect the market competitiveness of domestic raw materials, which have been pushed back by Chinese manufacturers. If the domestic production base is weakened, not only will the farmers suffer but the supply and demand of raw materials will also be manipulated, safety management control will be reduced, and the development of oriental herbal products using domestic raw materials will be hurt. Therefore, in the promotion of international standardization, it is necessary not only to reflect the value of Korean herbal medicine but also to provide strategic responses to protect the domestic production base. However, in the case of recent initiatives, there is no precedent in analyzing influence on the production partners and the related industries. In addition, there are few related papers and reports on the subject, so the publicity process has not been done sufficiently. In response to this, this study will examine the countermeasures against the international standardization of herbal medicines through reviewing its present status and evaluating the agenda of the Korean initiative.

• Journal of the Korean Recycled Construction Resources Institute
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• v.6 no.3
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• pp.199-206
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• 2018

Due to the advantages of less raw materials and fossil fuel consumption, lower carbon footprint, and the capability of pavement performance improvement, the recycling technology of asphalt is developed and applied for road rehabilitation and construction in the western countries over the past two decades. Cold recycled asphalt mixtures are bituminous materials normally made by mixing recycled aggregate from wasted asphalt with an asphalt emulsion and water at room temperature. This paper aims at investigating the properties of cold recycled asphalt mixture with alkali-activated filler according to wasted asphalt aggregate content. As a result, as the content of wasted asphalt aggregate increased, the marshall stability of cold recycled asphalt mixture decreased and void ratio increased. Also, grading curves for cold recycled asphalt mixture as specified in GR criteria were satisfied in all aggregate mixing conditions regardless of the wasted asphalt aggregate content.

• Advances in concrete construction
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• v.6 no.2
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• pp.123-143
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• 2018

Self compacting concrete (SCC) has good flowability, passability and segregation resistance because of voluminous cementitious material & high coarse aggregate to fine aggregate ratio, and high free water availability. But these factors make it highly susceptible to shrinkage. Fibers are known to reduce shrinkage in concrete mixes. Until now for conserving cement, only pozzolanic materials are admixed in concrete to yield a SCC. Hence, this study compares the use of wollastonite micro fiber (WMF), a cheap pozzolanic easily processed raw mineral fiber, and flyash in yielding economical SCC for rigid pavement. Microsilica was used as a complimentary material with both admixtures. Since WMF has large surface area ($827m^2/kg$), is acicular in nature; therefore its use in yielding SCC was dubious. Binary and ternary mixes were constituted for WMF and flyash, respectively. Paste mixes were tested for compatibility with superplasticizer and trials were performed on a normal concrete mix of flexural strength 4.5 MPa to yield SCC. Flexural strength test and restrained shrinkage test were performed on those mixes, which qualified self compacting criteria. Results revealed that WMF admixed pastes have high water demand, and comparable setting times to flyash mixes. Workability tests showed that 20% WMF with microsilica (5-7.5%) is efficient enough in achieving SCC and higher flexural strength than normal concrete at 90 days. Also, stress rate due to shrinkage was lesser and time duration for final strain was higher in WMF admixed SCC which encourages its use in yielding a SCC than pozzolanic materials.

• Journal of the Korean Applied Science and Technology
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• v.35 no.1
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• pp.235-246
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• 2018

Paeony has pharmacological activities such as anti-inflammatory, anti-allergic, anti-bacterial, central inhibitory, gastric secretion inhibition, and antispasmodic activities. In addition, its antioxidant activity and whitening effect being reported, thus it is being explored as raw materials for cosmetics. We compared the changes in the contents of paeoniflorin and paeonol in Peony extracts, depending on the changes of extracting solvents, temperature and time. The HPLC method was set up for simultaneous analysis, the system suitabilities were confirmed by using the calibration curves and the QC samples for each assay batch. Paeonol was detected only in roots, and paeoniflorin was higher in leaf and flower than root. Higher concentrations of both ingredients were extracted when the root was used after grinding to a suitable size, and when 30% 1,3-butylene glycol was used as the extraction solvent. Also the concentrations tended to increase at higher temperature and longer time, but the increase was gradual at over $75^{\circ}C$ and 4 hours. The ratio of root, leaf and flower was determined to be 2+2+1g/0.5kg of batch, reaching the contents criteria of paeoniflorin and paeonol. Finally, we selected as the best extraction condition when the raw materials are mixed with 2+2+1g/0.5kg and extracted with 30% 1,3-butylene glycol as an extraction solvent at $75^{\circ}C$ for 4 hours, considering both the concentrations of two components and the cost of raw materials and manufacturing process, The extraction units were scaled up to 10 kg under this condition.

• The Korean Journal of Food And Nutrition
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• v.16 no.4
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• pp.397-405
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• 2003

The cleanness of Korean(n=292), Chinese(n=46), Japanese(n=114) and Western(n=74) styles restaurants in 25 districts in Seoul was evaluated in terms of kitchen area(6 criteria), handling of raw materials(3 criteria), hygiene practice for cook(1 criteria), treatment of wastes(2 criteria) and hall(2 criteria). The western-style restaurants were scored the highest points in all criteria. The other three restaurants were poorly evaluated compared with western-style ones in kitchen area, including cleanness of inside of the kitchen, hygiene practice, ventilation and working environment, drainage, and storage of utensils. The most critical criterion which represents the overall evaluation was the ventilation and working environment of the kitchen for Chinese, Japanese and Western-style restaurants, and was the cleanness of inside the kitchen for Korean-style restaurants.

• Korean Journal of Occupational Health Nursing
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• v.25 no.1
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• pp.65-74
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• 2016

Purpose: The purpose of this study is to predict industrial accident rate using time series analysis. Methods: The rates of industrial accident and occupational injury death were analyzed using industrial accident statistics analysis system of the Korea Occupational Safety and Health Agency from 2001 to 2014. Time series analysis was done using the most recent data, such as raw materials of Economically Active Population Survey, Economic Statistics System of the Bank of Korea, and e-National indicators. The best-fit model with time series analysis to predict occupational injury was developed by identifying predictors when the value of Akaike Information Criteria was the lowest point. Variables into the model were selected through a series of expertises' consultations and literature review, which consisted of socioeconomic structure, labor force structure, working conditions, and occupational accidents. Results: Indexes at the meso- and macro-levels predicting well occurrence of occupational accidents and occupational injury death were labor force participation rate for ages 45-49 and budget for small scaled workplace support. The rates of industrial accident and occupational injury death are expected to decline. Conclusion: For reducing industrial accident continuously, we call for safe employment policy of economically active middle aged adults and support for improving safety work environment of small sized workplace.

• Analytical Science and Technology
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• v.31 no.5
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• pp.179-184
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• 2018

Diphencyprone (DPCP) is frequently used as a compounded preparation in dermatology for the treatment of alopecia and recalcitrant warts based on the immune reaction of skin allergy. However, DPCP is a non-recognized agent in Pharmacopoeia, because there are no criteria or analytical method for quality control of its powder and formulation. DPCP is unstable under light irradiation because as it easily decomposes to diphenylacetylene (DPA). This study aims to develop a simultaneous HPLC analytical method for analyzing DPCP and DPA in the raw materials and compounded preparation. The method required a C18 column ($250{\times}4.6mm$, $5{\mu}m$) at $40^{\circ}C$ with a mobile phase of (A) 0.01 M phosphoric acid in water and (B) acetonitrile at UV 220 nm. DPA conversion to DPCP in the powder and compounded preparations was accelerated after light exposure for 60 min. In addition, this resulted in different patterns depending on the wavelength of light and the formulation. That is, DPCP in compounded preparation was more unstable than that in the powder. However, the DPCP formulation in amber bottles was observed to remain stable, although the measured concentrations of DPCP were somewhat different from the nominal concentration of the compounded preparations. The control of the exact concentration is required for effective disease treatment, depending on the state of the patient. In conclusion, these results will be useful for the recognition of DPCP in Pharmacopoeia and new DPCP formulation development to prevent photodecomposition.

• Journal of Biomedical Engineering Research
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• v.44 no.1
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• pp.41-52
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• 2023

With the international change in the medical device market owing to the development of innovative medical engineering and the use of various raw materials, a systematic and rational medical device classification system is needed to safely manage newly developed medical devices. This study aims to improve the domestic medical device classification system by proposing product establishment and segmentation. It is based on medical device products from the United States and Europe that are only available in foreign systems and are more subdivided than domestic products. This study analyzes and compares the domestic and foreign medical device classification systems by examining laws, guidelines, and analysis reports in Korea, the United States, and Europe. In accordance with product establishment and segmentation criteria, products subject to improvement are presented. This study contributes to safely managing medical devices that do not fit with the current classification system and to solving the confusion caused by the lack of international harmony in product classification systems.