• 제목/요약/키워드: Coupled System

검색결과 3,193건 처리시간 0.032초

A Novel Phototransduction Pathway in the Pineal Gland and Retina

  • Okano, Toshiyuki;Kasahara, Takaoki;Fukada, Yoshitaka
    • Journal of Photoscience
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    • 제9권2호
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    • pp.246-248
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    • 2002
  • Light is a major environmental signal for entrainment of the circadian clock, but little is known about the phototransduction pathway triggered by light-activation of photoreceptive molecule(s) responsible for the phase shift of the clock in vertebrates. The chicken pineal gland and retina contain the autonomous circadian oscillators together with the photic entrainment pathway, and hence they provide useful experimental model for the clock system. We previously demonstrated the expression and light-dependent activation of rod-type transducin $\alpha$-subunit (Gtl$\alpha$) in the chicken pineal gland. It is unlikely, however, that the pineal Gt$_1$$\alpha$ plays a major role in the photic entrainment, because the light-induced phase shift is unaffected by bloking the signaling function of Gt$_1$$\alpha$. Here, we show the expression of G 11 $\alpha$, an $\alpha$-subunit of another heterotrimeric G-protein, in the chicken pineal gland and retina by cDNA cloning, Northern blot and Western blot analyses. GIl$\alpha$-immunoreactivity was colocalized with pinopsin in the chicken pineal cells and it was found predominantly at the outer segments of photoreceptor cells in the retinal sections, suggesting functional coupling of G11 $\alpha$ with opsins in the both the tissues. By coimmunoprecipitation experiments using the retina, we showed the light- and GTP-dependent interaction between rhodopsin and G11 $\alpha$. Upon ectopic expression of a Gq/ 11-coupled receptor in cultured pineal cells, pharmacological (non-photic) activation of endogenous G11 induced phase-dependent phase shifts of the melatonin rhythm in a manner very similar to the effect of light. These results suggested opsin-G11 pathway contributing to the photic entrainment of the circadian clock.

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$CF_4$/Ar 플라즈마를 이용한 SBT 박막 식각에 관한 연구 (Study of characteristics of SBT etching using $CF_4$/Ar Plasma)

  • 김동표;서정우;김승범;김태형;장의구;김창일
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 1999년도 하계학술대회 논문집 D
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    • pp.1553-1555
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    • 1999
  • Recently, $SrBi_2Ta_2O_9$(SBT) and $Pb(ZrTi)O_3$(PZT) were much attracted as materials of capacitor for ferroelectric random access memory(FRAM) showing higher read/write speed, lower power consumption and nonvolartility. Bi-layered SBT thin film has appeared as the most prominent fatigue free and low operation voltage for use in nonvolatile memory. To highly integrate FRAM, SBT thin film should be etched. A lot of papers on SBT thin film and its characteristics have been studied. However, there are few reports about SBT thin film due to difficulty of etching. In order to investigate properties of etching of SBT thin film, SBT thin film was etched in $CF_4$/Ar gas plasma using magnetically enhanced inductively coupled plasma (MEICP) system. When $CF_4/(CF_4+Ar)$ is 0.1, etch rate of SBT thin film was $3300{\AA}/min$, and etch rate of Pt was $2495{\AA}/min$. Selectivities of SBT to Pt. $SiO_2$ and photoresist(PR) were 1.35, 0.6 and 0.89, respectively. With increasing $CF_4$ gas, etch rate of SBT thin film and $P_t$ decreased.

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PET 기질의 전처리효과가 상온 ECR 화학증착법에 의해 증착된 구리박막의 계면접착력에 미치는 영향 (Effects of Pretreatments of PET Substrate on the Adhesion of Copper Films Prepared by a Room Temperature ECR-MOCVD Method)

  • 현진;전법주;변동진;이중기
    • 한국재료학회지
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    • 제14권3호
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    • pp.203-210
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    • 2004
  • Effects of various pretreatments on the adhesion of copper-coated polymer films were investigated. Copper-coated polymer films were prepared by an electron cyclotron resonance-metal organic chemical vapor deposition (ECR-MOCVD) coupled with a DC bias system at room temperature. PET(polyethylene terephthalate) film was employed as a substrate material and it was pretreated by industrially feasible methods such as chromic acid, sand-blasting, oxygen plasma and ion-implantation treatment. Surface characterization of the copper-coated polymer film was carried out by AFM(Atomic Force Microscopy) and FESEM(Field Emission Scanning Electron Microscopy). Surface energy was calculated by based on the value of the contact angle measured. The adhesion of copper/PET films was determined by a pull-off test according to ASTM D-5179. It was found that suitable pretreatment of the PET substrate was required for obtaining good adhesion property between copper films and the substrate. In this study the highest adhesion was observed in sand-blasting, and then followed by those of acid and oxygen plasma treatment. However, the effect of surface energy was insignificant in our experimental range. This is probably due to compensating the difference in surface energy from various pretreatments by exposing substrate to ECR plasma for 5 min or longer at the early stage of the copper deposition. Therefore, it can be concluded that surface roughness of the polymer substrate plays an important role to determine the adhesion of copper-coated polymer for the deposition of copper by ECR-MOCVD.

침지형 분리막 생물반응기에서 미생물 농도와 슬러지 부하에 따른 미생물 활성 변화와 막오염 특성 연구 (Effects of Biomass Concentration and Sludge Loading Rate on Bioactivity and Membrane Fouling in a Submerged Membrane Bioreactor System)

  • 탁태문;배태현;장경국
    • 멤브레인
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    • 제14권4호
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    • pp.289-297
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    • 2004
  • 유기물과 질소를 동시에 제거하기 위하여 연속회분식으로 운전한 MBR (membrane bioreactor)시스템에서 미생물농도와 슬러지 부하량이 막오염과 미생물 활성에 미치는 영향을 살펴보았다. 막오염은 MLSS (mixed liquor suspended solid) 농도 증가에 따라 조금씩 증가하는 경향을 보였고, 그 효과는 비포기 조건보다 포기 조건에는 좀더 두드러지게 나타났다. MLSS 농도는 막오염에 직접적인 커다란 영향을 주지는 않으나, 지나치게 높은 MLSS에서 유도되는 낮은 슬러지 부하에서는 막오염이 크게 증가하는 현상이 발견되었고, 이러한 조건에서는 포기에 의한 막 세척 효과도 크게 줄어들었다. 미생물의 개별 활성도는 슬러지 부하가 감소할수록 지속적으로 감소하는 경향을 나타내었다 반응조 전체 활성도 또한 17,000 mg/L 이상의 높은 MLSS로부터 유도되는 낮은 슬러지 부하율에서는 높은 미생물 농도에도 불구하고 오히려 감소했는데 이는 기질 부족으로 인한 경쟁으로 활성도가 떨어지고, 용액의 점성 증가로 인해 산소 전달율이 저하되었기 때문이다.

거대 부체구조물의 2차원 유연체 해석 및 거동 (Two Dimensional Flexible Body Response of Very Large Floating Structures)

  • Namseeg Hong
    • 한국해안해양공학회지
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    • 제8권4호
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    • pp.274-286
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    • 1996
  • 2차원 유연체해석 이론(수탄성 이론)을 여러개의 단위체 연결로 이루어진 거대 부체구조물의 해석에 적용하였다. 동수역학적 계수를 구하기 위해 경계요소법과 그린함수법이 사용되었으며 부체자체는 연직방향으로 파랑에 반응하는 연체보로 정수역학적 탄성계수에 대한 운동을 고려하여 운동방정식이 유도된다. 두가지 다른 형식의 연결, 즉 회전강성을 가진 것과 강성을 무시한 핀 형식의 연결요소가 고려되며 반잠수한 부체에 대해 해석결과가 제시된다. 해석결과는 거대 부체구조물의 설계에 필요한 변위와 내력에 관한 개념을 제시한다. 또한 수치해석 결과에 따르면 부체의 움직임은 핀연결이 강성체 연결보다 더 크며 부체의 내력휨 응력은 강성체 연결에서 휠씬 더 크게 증가하였다.

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거대 구조물의 유체-구조 연계 해석을 위한 효과적인 보간기법에 대한 연구 (A Study on the Effective Interpolation Methods to the Fluid-Structure Interaction Analysis for Large-Scale Structure)

  • 이기두;이영신;김동수;이대열
    • 한국항공우주학회지
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    • 제37권5호
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    • pp.433-441
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    • 2009
  • 대부분의 자연현상은 다학제 특성을 갖고 표현된다. 유체-구조 연계(FSI) 문제의 경우 기존에 검증된 전산유체 해석 프로그램 및 구조해석 프로그램을 그대로 사용할 수 있다는 장점 때문에 약결합 방식이 일반적으로 이용된다. 그러나 약결합을 이용하여 해석을 수행하기 위해서는 서로 다른 특성을 갖는 격자시스템으로 발생되는 자료의 교환을 위해서 보간 및 사상이 필수적이다. 본 연구에서는 전역지지 및 국부지지 방사기저함수(RBF)를 이용한 보간 및 가상일의 원리를 적용한 사상의 성능을 단순 3차원 형상에 적용하여 검토하였다. 국부지지 RBF에 공간분할 트리의 일종으로 빠른 공간 탐색을 가능하게 해주는 kd-tree를 사용하는 경우 효과적으로 거대 구조물의 FSI에도 보간 및 사상이 적용 가능함을 여객기 형상의 항공기 모형을 이용하여 제시하였다.

추출크로마토그래피와 유도결합플라스마 원자방출분광법을 이용한 이산화우라늄분말 중 미량금속불순물 분석 (Determination of the Trace Elements in $UO_2$ Powder by ICP-AES Directyl Coupled with Extraction Chromatography)

  • 최광순;이창헌;표형열;한선호;서무열;엄태윤;이계호
    • 대한화학회지
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    • 제37권9호
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    • pp.813-819
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    • 1993
  • $UO_2$ 분말에 미량 함유되어 있는 금속불순물들을 신속하게 정량하고 분석과정에서 발생되는 폐액의 양을 줄이기 위하여, 우라늄용액으로부터 미량금속불순물들을 분리함과 동시에 ICP-AES로 분석할 수 있는 장치를 구성하였다. 미량금속불순물들을 분리하기 위하여, 폴리에틸렌으로 제작한 분리컬럼(내경 : 0.7cm, 길이 : 7 cm)에 TBP(tri-n-butyl phosphate)를 입힌 테프론 분말(약 $330\;{\mu}m$)을 충진하고, 분리컬럼의 출구를 ICP-AES의 시료주입구에 연결시켰다. $UO_2$ 분말에 미량 함유되어 있는 몰리브덴을 비롯한 11개 원소를 분리와 동시에 정량할 수 있었으며, 이들 원소들에 대한 회수율은 용매추출법에서와 거의 동일한 $91{\sim}110%$로서 핵연료 제조공정의 품질관리에 적용이 가능하였다.

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Fabrication of Artificial Sea Urchin Structure for Light Harvesting Device Applications

  • Yeo, Chan-Il;Kwon, Ji-Hye;Kim, Joon-Beom;Lee, Yong-Tak
    • 한국진공학회:학술대회논문집
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    • 한국진공학회 2012년도 제43회 하계 정기 학술대회 초록집
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    • pp.380-381
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    • 2012
  • Bioinspired sea urchin-like structures were fabricated on silicon by inductively coupled plasma (ICP) etching using lens-like shape hexagonally patterned photoresist (PR) patterns and subsequent metal-assisted chemical etching (MaCE) [1]. The lens-like shape PR patterns with a diameter of 2 ${\mu}m$ were formed by conventional lithography method followed by thermal reflow process of PR patterns on a hotplate at $170^{\circ}C$ for 40 s. ICP etching process was carried out in an SF6 plasma ambient using an optimum etching conditions such as radio-frequency power of 50 W, ICP power of 25 W, SF6 flow rate of 30 sccm, process pressure of 10 mTorr, and etching time of 150 s in order to produce micron structure with tapered etch profile. 15 nm thick Ag film was evaporated on the samples using e-beam evaporator with a deposition rate of 0.05 nm/s. To form Ag nanoparticles (NPs), the samples were thermally treated (thermally dewetted) in a rapid thermal annealing system at $500^{\circ}C$ for 1 min in a nitrogen environment. The Ag thickness and thermal dewetting conditions were carefully chosen to obtain isolated Ag NPs. To fabricate needle-like nanostructures on both the micron structure (i.e., sea urchin-like structures) and flat surface of silicon, MaCE process, which is based on the strong catalytic activity of metal, was performed in a chemical etchant (HNO3: HF: H2O = 4: 1: 20) using Ag NPs at room temperature for 1 min. Finally, the residual Ag NPs were removed by immersion in a HNO3 solution. The fabricated structures after each process steps are shown in figure 1. It is well-known that the hierarchical micro- and nanostructures have efficient light harvesting properties [2-3]. Therefore, this fabrication technique for production of sea urchin-like structures is applicable to improve the performance of light harvesting devices.

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집적형 하이브리드 구동장치의 성능시험 (Performance Testing of an Integrated Hybrid Actuator)

  • 현철봉;김태렬;구남서;배병운;김태흔;고한서;윤기원
    • 한국항공우주학회지
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    • 제41권1호
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    • pp.25-30
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    • 2013
  • 집적형 하이브리드 구동장치는 적층형 압전재료(압전스택)를 이용한 마이크로 펌프에서 토출되는 유체로 피스톤을 구동시키는데 크기는 작으면서도 큰 구동력과 높은 속도를 동시에 출력할 수 있는 새로운 개념의 통합 구동장치로서 현재 소형화 및 고출력을 요구하는 항공 우주, 유도무기 등 다양한 분야에서 광범위하게 연구되고 있다. 본 연구에서는 이러한 하이브리드 구동장치의 구동원리 및 성능 시험에 대해 소개하였다. 우선 구동장치의 주 동력인 압전 스택의 성능 시험을 수행함으로써 압전 스택의 구동전력과 구동시간에 따른 성능 변화를 관찰하였고 다음 구동장치의 성능 시험을 통해 구동장치의 최대 이송속도와 최대 구동력을 측정하였다. 구동장치의 최대 이송속도는 53.3 mm/s로, 최대 구동력은 240.7 N으로, 최대 일률은 3.2 W로 측정되었다.

Seismic assessment of transfer plate high rise buildings

  • Su, R.K.L.;Chandler, A.M.;Li, J.H.;Lam, N.T.K.
    • Structural Engineering and Mechanics
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    • 제14권3호
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    • pp.287-306
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    • 2002
  • The assessment of structural performance of transfer structures under potential seismic actions is presented. Various seismic assessment methodologies are used, with particular emphasis on the accurate modelling of the higher mode effects and the potential development of a soft storey effect in the mega-columns below the transfer plate (TP) level. Those methods include response spectrum analysis (RSA), manual calculation, pushover analysis (POA) and equivalent static load analysis (ESA). The capabilities and limitations of each method are highlighted. The paper aims, firstly, to determine the appropriate seismic assessment methodology for transfer structures using these different approaches, all of which can be undertaken with the resources generally available in a design office. Secondly, the paper highlights and discusses factors influencing the response behaviour of transfer structures, and finally provides a general indication of their seismic vulnerability. The representative Hong Kong building considered in this paper utilises a structural system with coupled shear walls and moment resisting portal-frames, above and below the TP, respectively. By adopting the wind load profile stipulated in the Code of Practice on Wind Effects: Hong Kong-1983, all the structural members are sized and detailed according to the British Standards BS8110 and the current local practices. The seismic displacement demand for the structure, when built on either rock or deep soil sites, was determined in a companion paper. The lateral load-displacement characteristic of the building, determined herein from manual calculation, has indicated that the poor ductility (brittle nature) of the mega-columns, due mainly to the high level of axial pre-compression as found from the analysis, cannot be effectively alleviated solely by increasing the quantity of confinement stirrups. The interstorey drift demands at lower and upper zones caused by seismic actions are found to be substantially higher than those arising from wind loads. The mega-columns supporting the TP and the coupling beams at higher zones are identified to be the most vulnerable components under seismic actions.