• Title/Summary/Keyword: Corona-virus

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Effect of Recombinant Lactobacillus Expressing Canine GM-CSF on Immune Function in Dogs

  • Chung, Jin-Young;Sung, Eui-Jae;Cho, Chun-Gyu;Seo, Kyoung-Won;Lee, Jong-Soo;Bhang, Dong-Ha;Lee, Hee-Woo;Hwang, Cheol-Yong;Lee, Wan-Kyu;Youn, Hwa-Young;Kim, Chul-Joong
    • Journal of Microbiology and Biotechnology
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    • v.19 no.11
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    • pp.1401-1407
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    • 2009
  • Many Lactobacillus strains have been promoted as good probiotics for the prevention and treatment of diseases. We engineered recombinant Lactobacillus casei, producing biologically active canine granulocyte macrophage colony stimulating factor (cGM-CSF), and investigated its possibility as a good probiotic agent for dogs. Expression of the cGM-CSF protein in the recombinant Lactobacillus was confirmed by SDS-PAGE and Western blotting methods. For the in vivo study, 18 Beagle puppies of 7 weeks of age were divided into three groups; the control group was fed only on a regular diet and the two treatment groups were fed on a diet supplemented with either $1\times10^9$ colony forming units (CFU)/day of L. casei or L. casei expressing cGM-CSF protein for 7 weeks. Body weight was measured, and fecal and blood samples were collected from the dogs during the experiment for the measurement of hematology, fecal immunoglobulin (Ig)A and IgG, circulating IgA and IgG, and canine corona virus (CCV)-specific IgG. There were no differences in body weights among the groups, but monocyte counts in hematology and serum IgA were higher in the group receiving L. casei expressing cGM-CSF than in the other two groups. After the administration of CCV vaccine, CCV-specific IgG in serum increased more in the group supplemented with L. casei expressing cGM-CSF than the other two groups. This study shows that a dietary L. casei expressing cGM-CSF enhances specific immune functions at both the mucosal and systemic levels in puppies.

A Performance Model of Non-facing Real-time Video Lecture Service: Focusing the Perspective of Corona19 Virus Environment and Learner's Orientation (비대면 실시간 영상강의 서비스 성과 모형: 코로나19 바이러스 환경 및 학습자 성향 관점)

  • Ahn, Yeon S.
    • Journal of Service Research and Studies
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    • v.10 no.3
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    • pp.55-66
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    • 2020
  • This study was attempted to demonstrate the service performance of non-face-to-face real-time video lecture service conducted in the coronavirus crisis in early 2020. Lecture service is divided into service production and service delivery from a service system perspective, and its role of lecture service system and the relationship between lecture service benefits and service satisfaction perceived by learners is demonstrated. In order to demonstrate this structural impact relationship, the result of analysis through a questionnaire survey on a total of 268 undergraduate students at G University, showed that the role and level of the non-face-to-face real-time video lecture service system affects the service convenience and service satisfaction. In the additional analysis, the learning orientation learners group perceived the service system level or role in the lecture service and the service benefit itself higher than the relationship orientation learners group. In the past, when a face-to-face class was conducted, learners group who attended a lot of extra curriculum activities perceived the benefits of coronavirus prevention lower than those of a group that did not. In this way, it is necessary to supplement the lecture service system by identifying the role expectation in the lecture service for the high relationship orientation group and the preferring extra curriculum activity group after detail research.

The Effect of COVID-19 Pandemic and Operanting Cycle on Asymmetric Cost Behavior in Food Service Industry (코로나19 팬데믹과 영업순환주기가 외식업체의 원가 비대칭적 행태에 미치는 영향)

  • Park, Won
    • Journal of Digital Convergence
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    • v.20 no.4
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    • pp.215-224
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    • 2022
  • This study tried to examine the effect of cost asymmetry on food service companies and what characteristics affect such cost behavior. This study analyses cost behavior for cost of good sold, selling, general and administrative cost over the 2019-2020 period. Also, the rate of change in activity level was measured using change in sales. This study measures the behavior of cost using the research model of [1]. As a result of the analysis, it was found that food service companies exhibited cost asymmetric behavior as their sales level decreased. In addition, the cost asymmetric behavior has been strengthened since the corona virus, and the shorter the operating cycle. Lastly, the shorter the inventory holding period and the collection period of accounts receivable, which are components of the operating cycle, more strengthen asymmetric behavior of costs. These results seem to be meaningful in examining the cost structure and factors that may affect the structure for food service industry. This has approached the cost aspect of the situation faced by service food companies due to COVID-19, and it can be suggested that this pandemic can lead to cost reduction due to a decrease in corporate sales.

Trend Analysis of Corona Virus(COVID-19) based on Social Media (소셜미디어에 나타난 코로나 바이러스(COVID-19) 인식 분석)

  • Yoon, Sanghoo;Jung, Sangyun;Kim, Young A
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.22 no.5
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    • pp.317-324
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    • 2021
  • This study deals with keywords from social media on domestic portal sites related to COVID-19, which is spreading widely. The data were collected between January 20 and August 15, 2020, and were divided into three stages. The precursor period is before COVID-19 started spreading widely between January 20 and February 17, the serious period denotes the spread in Daegu between February 18 and April 20, and the stable period is the decrease in numbers of confirmed infections up to August 15. The top 50 words were extracted and clustered based on TF-IDF. As a result of the analysis, the precursor period keywords corresponded to congestion of the Situation. The frequent keywords in the serious period were Nation and Infection Route, along with instability surrounding the Treatment of COVID-19. The most common keywords in all periods were infection, mask, person, occurrence, confirmation, and information. People's emotions are becoming more positive as time goes by. Cafes and blogs share text containing writers' thoughts and subjectivity via the internet, so they are the main information-sharing spaces in the non-face-to-face era caused by COVID-19. However, since selectivity and randomness in information delivery exists, a critical view of the information produced on social media is necessary.

A Longitudinal Comparative Study of Two Periods regarding the Influences of Psycho-Social Factors on Emotional Distress among Korean Adults during the Corona virus Pandemic(COVID-19) (코로나 19 팬데믹 시기 동안 한국인의 정서적 디스트레스에 영향을 미치는 심리·사회적 요인의 영향력에 대한 종단 두시점 비교연구)

  • Lee, Dong-Hun;Kim, Ye-Jin;Hwang, Hee-Hun;Nam, Seul-Ki;Jung, Da-Song
    • Korean Journal of Culture and Social Issue
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    • v.27 no.4
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    • pp.629-659
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    • 2021
  • This study compared the influences of Korean psycho-social experiences on emotional-distress(stress, depression, anxiety, anger) of Koreans between two-periods during COVID-19. First, an online survey was conducted among 600 participants between April 13, 2020 and 21, while WHO had declared the pandemic, and Daegu-Gyungbuk were declared as a special-disaster area. Second, an online survey was conducted among 482 participants out of 600 study participants from the first study during August 21 to September 2, while COVID-19 re-spreaded around the world, and total confirmed cases were over 1,000 for a week in Seoul-Gyeonggi province. Hierarchical-regression analysis was used to determine the influence of personal characteristics, fear and social constraints, relationship conflict and income-decreasing factors on stress, depression, anxiety, anger in the two-time points. Results suggest that gender, quality-of-life, 'frequent information-checking about COVID-19', 'fear of unpredictability' and 'difficulties on hospital treatment access' predicted distress(stress, depression, anxiety, anger) at both Time1 and 2. 'Difficulties with official schedule' predicted distress at Time 1, and age, vulnerability to infection and difficulties with personal schedules predicted distress(stress, depression, anxiety, anger) at Time 2. Based on the reseults, implications and recommendations were presented.

The study of security management for application of blockchain technology in the Internet of Things environment (Focusing on security cases in autonomous vehicles including driving environment sensing data and occupant data) (사물인터넷 환경에서 블록체인 기술을 이용한 보안 관리에 관한 소고(주행 환경 센싱 데이터 및 탑승자 데이터를 포함한 자율주행차량에서의 보안 사례를 중심으로))

  • Jang Mook KANG
    • Convergence Security Journal
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    • v.22 no.4
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    • pp.161-168
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    • 2022
  • After the corona virus, as non-face-to-face services are activated, domain services that guarantee integrity by embedding sensing information of the Internet of Things (IoT) with block chain technology are expanding. For example, in areas such as safety and security using CCTV, a process is required to safely update firmware in real time and to confirm that there is no malicious intrusion. In the existing safe security processing procedures, in many cases, the person in charge performing official duties carried a USB device and directly updated the firmware. However, when private blockchain technology such as Hyperledger is used, the convenience and work efficiency of the Internet of Things environment can be expected to increase. This article describes scenarios in how to prevent vulnerabilities in the operating environment of various customers such as firmware updates and device changes in a non-face-to-face environment. In particular, we introduced the optimal blockchain technique for the Internet of Things (IoT), which is easily exposed to malicious security risks such as hacking and information leakage. In this article, we tried to present the necessity and implications of security management that guarantees integrity through operation applying block chain technology in the increasingly expanding Internet of Things environment. If this is used, it is expected to gain insight into how to apply the blockchain technique to guidelines for strengthening the security of the IoT environment in the future.

A Study on the Intention to Use Biometric Authentication When Using Mobile Easy Payment Service: Focusing on the Comparison of Experienced and Non-Experienced Persons (모바일 간편결제 서비스 이용 시 생체인증 사용의도에 관한 연구: 경험자와 비경험자 비교를 중심으로)

  • Jae-Seung Ju;Won-Boo Lee
    • Information Systems Review
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    • v.23 no.4
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    • pp.1-22
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    • 2021
  • In the newly encountered economy caused by the Corona virus Disease-19, remote transaction becomes a new normal that disrupt traditional economic order. In the middle of the disruption, mobile tech is placed and remote finance on mobile is highly noticed and considered as an infra-tech to support the new ecology, In mobile finance. remote payment is becoming the most common service and personal identification on it is critical to operate the new service. There are various means of remotely identifying a person. Recently the use of biometric information is increasing. In this study, a correlation analysis was conducted on factors that effects to biometrics usage and the intention to use in remote personal identification. Variables for critical factor in the remote identification were classified into 4 groups such as Performance expectancy, Effort expectancy, Social influence, and Security. The empirical analysis based on the Unified Theory of Acceptance and Use of Technology (UTAUT) was conducted. The relationship between variables and the intention to use is also analyzed. In the study, stepwise regression analysis was conducted four times in which variables were adjusted in individual stage. As a result, the analysis suggests that performance expectancy, effort expectancy, social influence, security have positive effects for intention to use. Additionally, effort expectancy and security have moderating effects to intention to use depends on biometric authentication experience. The analysis has shown positive effect of variables grouped on the intention to use them. It also suggests that the intention to use biometric authentication will quickly grow. This study is expected to make a contribution to utilize and improve the use of biometric information in mobile payment.

A Study of the Model Christian Familial-Spiritual Education for The Era of Covid-19 (코로나19 시대의 기독교적 가정영성교육 모형: 비블리오드라마를 중심으로)

  • Choi, Eun Taek
    • Journal of Christian Education in Korea
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    • v.63
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    • pp.91-120
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    • 2020
  • This study suggests a spiritual education for the Christian family as a strategy to cope with the risky situation of the Korean Church during the Covid-19 pandemic. Today, we live in a chaotic epoch since the rapid development of the science caused the Fourth Industrial Revolution and the Covid-19 pandemic gave rise to a wide array of changes throughout the society. Korean Church in these circumstances is required to have relevant responses to the kaleidoscopic changes. Especially, not to mention the face-to-face public worship service, in the situation where the congregation members even find it difficult to meet one another in a small group, it becomes a crucial issue how Christians maintain their faith and community in the healthy spirituality. As such, viewing that Christian education within the family will become much more important, this study conducts research for familial-spiritual education. For the research, this paper, first of all, attempts to understand the era of Covid-19. It is to see what the Novel Corona Virus is and what the feature of the epoch of Covid-19 might be. Based upon the understanding, this research discusses what Christian spirituality is asked for and the orientation towards which Christian education should go on. It is particularly to say that a spiritual education for the family becomes integral. The education for the family might be possible through Bibliodrama so that this study establishes a specific model of Christian education employing Bibliodrama. The discussion above shows three academic significances. First, this paper, within the domain of Christian education, suggests an alternative research which is to solve Korean Church's diverse problems caused by Covid-19. Second, this research attempts an analytical understanding of the Covid-19 period within the Christian education area. Finally, when specific and practical research for the field of Christian education during the Covid-19 pandemic is required, this study considers that Christian education within the family is overarching, thus proposing a specific model for familial-spiritual education hiring Bibliodrama.

Epidemic acute interstitial pneumonia in children occurred during the early 2006s (2006년 초에 유행한 소아 급성 간질성폐렴)

  • Cheon, Chong Kun;Jin, Hyun-Seung;Kang, Eun Kyeong;Kim, Hyo Bin;Kim, Byoung-Joo;Yu, Jinho;Park, Seong Jong;Hong, Soo-Jong;Park, June Dong
    • Clinical and Experimental Pediatrics
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    • v.51 no.4
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    • pp.383-390
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    • 2008
  • Purpose : This study was aimed to analyze the clinical characteristics of patients with acute interstitial pneumonia who had presented similar clinical patterns from March to June, 2006 and to describe our experience of treatment and to identify risk factors associated with prognosis. Methods : The clinical characteristics, radiologic and histopathologic findings and response to steroids of 15 patients (non-survival group [n=7] and survival group [control, n=8]) with acute interstitial pneumonia were investigated through the review of medical records. Results : The mean age of the patients was 26 (range: 3-48) months. Cough, cyanosis and fever were frequent symptoms. The most frequent radiologic findings on admission were pneumomediastium and extensive ground glass opacity. Surgical lung biopsy was performed on 8/15 (53.3%) patients and diffuse alveolar damage was found. Mechanical ventilation was applied for 9/15 (60.0%) patients for 40 (range: 1-99) days. Five patients in survival group received steroid treatment and 7 patients in non-survivial group (P=0.20). One patient in survival group received steroid pulse treatment and 4 patients in non-survival group (P=0.12). Seven patients died all of respiratory failure. The survival rate was 53.4%. Conclusion : The patients with acute interstitial pneumonia which occurred on spring 2006 showed high mortality because of rapidly and extensively progressing pulmonary fibrosis and air leakage. Therefore, we should consider surgical lung biopsy and steroid application earlier. We should recognize this acute interstitial pneumonia occurring on spring in domestics and need to investigate the cause and treatment in large scale.

A Study on Kiosk Satisfaction Level Improvement: Focusing on Kano, Timko, and PCSI Methodology (키오스크 소비자의 만족수준 연구: Kano, Timko, PCSI 방법론을 중심으로)

  • Choi, Jaehoon;Kim, Pansoo
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.17 no.4
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    • pp.193-204
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    • 2022
  • This study analyzed the degree of influence of measurement and improvement of customer satisfaction level targeting kiosk users. In modern times, due to the development of technology and the improvement of the online environment, the probability that simple labor tasks will disappear after 10 years is close to 90%. Even in domestic research, it is predicted that 'simple labor jobs' will disappear due to the influence of advanced technology with a probability of about 36%. there is. In particular, as the demand for non-face-to-face services increases due to the Corona 19 virus, which is recently spreading globally, the trend of introducing kiosks has accelerated, and the global market will grow to 83.5 billion won in 2021, showing an average annual growth rate of 8.9%. there is. However, due to the unmanned nature of these kiosks, some consumers still have difficulties in using them, and consumers who are not familiar with the use of these technologies have a negative attitude towards service co-producers due to rejection of non-face-to-face services and anxiety about service errors. Lack of understanding leads to role conflicts between sales clerks and consumers, or inequality is being created in terms of service provision and generations accustomed to using technology. In addition, since kiosk is a representative technology-based self-service industry, if the user feels uncomfortable or requires additional labor, the overall service value decreases and the growth of the kiosk industry itself can be suppressed. It is important. Therefore, interviews were conducted on the main points of direct use with actual users centered on display color scheme, text size, device design, device size, internal UI (interface), amount of information, recognition sensor (barcode, NFC, etc.), Display brightness, self-event, and reaction speed items were extracted. Afterwards, using the questionnaire, the Kano model quality attribute classification of each expected evaluation item was carried out, and Timko's customer satisfaction coefficient, which can be calculated with accurate numerical values The PCSI Index analysis was additionally performed to determine the improvement priorities by finally classifying the improvement impact of the kiosk expected evaluation items through research. As a result, the impact of improvement appears in the order of internal UI (interface), text size, recognition sensor (barcode, NFC, etc.), reaction speed, self-event, display brightness, amount of information, device size, device design, and display color scheme. Through this, we intend to contribute to a comprehensive comparison of kiosk-based research in each field and to set the direction for improvement in the venture industry.