• Title/Summary/Keyword: Core Factor

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Local Drug Delivery System Using Biodegradable Polymers

  • Khang, Gil-Son;Rhee, John M.;Jeong, Je-Kyo;Lee, Jeong-Sik;Kim, Moon-Suk;Cho, Sun-Hang;Lee, Hai-Bang
    • Macromolecular Research
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    • v.11 no.4
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    • pp.207-223
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    • 2003
  • For last five years, we are developing the novel local drug delivery devices using biodegradable polymers, especially polylactide (PLA) and poly(D,L-lactide-co-glycolide) (PLGA) due to its relatively good biocompatibility, easily controlled biodegradability, good processability and only FDA approved synthetic degradable polymers. The relationship between various kinds of drug [water soluble small molecule drugs: gentamicin sulfate (GS), fentanyl citrate (FC), BCNU, azidothymidine (AZT), pamidronate (ADP), $1,25(OH)_2$ vitamin $D_3$, water insoluble small molecule drugs: fentanyl, ipriflavone (IP) and nifedipine, and water soluble large peptide molecule drug: nerve growth factor (NGF), and Japanese encephalitis virus (JEV)], different types of geometrical devices [microspheres (MSs), microcapsule, nanoparticle, wafers, pellet, beads, multiple-layered beads, implants, fiber, scaffolds, and films], and pharmacological activity are proposed and discussed for the application of pharmaceutics and tissue engineering. Also, local drug delivery devices proposed in this work are introduced in view of preparation method, drug release behavior, biocompatibility, pharmacological effect, and animal studies. In conclusion, we can control the drug release profiles varying with the preparation, formulation and geometrical parameters. Moreover, any types of drug were successfully applicable to achieve linear sustained release from short period ($1{\sim}3$ days) to long period (over 2 months). It is very important to design a suitable formulation for the wanting period of bioactive molecules loaded in biodegradable polymers for the local delivery of drug. The drug release is affected by many factors such as hydrophilicity of drug, electric charge of drug, drug loading amount, polymer molecular weight, the monomer composition, the size of implants, the applied fabrication techniques, and so on. It is well known that the commercialization of new drug needs a lot of cost of money (average: over 10 million US dollar per one drug) and time (average: above 9 years) whereas the development of DDS and high effective generic drug might be need relatively low investment with a short time period. Also, one core technology of DDS can be applicable to many drugs for the market needs. From these reasons, the DDS research on potent generic drugs might be suitable for less risk and high return.

A Study on the Influence of Characteristics of Service Nature Dynamic Capability on Organizational Innovation of Small and Medium size Manufacturing Firms (서비스 본질 특성과 동태적 역량이 중소제조기업의 조직혁신에 미치는 영향)

  • Lee, JeungSun;Kim, Hyunsoo
    • Journal of Service Research and Studies
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    • v.8 no.1
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    • pp.27-39
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    • 2018
  • This study is an empirical study to examine the effect of the characteristics of service nature of Korean small and medium manufacturing firms on organizational innovation. It is essential to know service in order for Korea, which has a strong image as a fast follower, to enhance the competitiveness of Small and Medium size Manufacturing firms. By analyzing the service characteristics phenomenon, it is possible to understand the service nature characteristics and to strengthen the capacity to meet them. In order to gain a new resource while achieving organizational innovation, the manufacturing industry can produce new demand for the main products with competitive advantage. The characteristics of service nature are derived from relationship, equality, interactivity, and experiential value. In order to enhance the competitiveness of small and medium size manufacturing firms, core competencies required for organizational innovation are set as dynamic competencies, and to prove it. The dynamic capacity was found to affect the relationship, interactivity, and experience value. It is proved that it is an important factor to promote organizational innovation as a capability to identify and actively utilize organizational innovation opportunities ahead of competitors in a rapidly changing environment. It is needed to confirm that large corporations, midsize companies, and overseas companies can achieve the same results.

Analysis of Socio-Scientific Issues(SSI) Programs in Korea (과학 관련 사회적 쟁점(Socio-Scientific Issues, SSI)을 활용한 국내 프로그램 분석)

  • Park, HyunJu;Kim, Nahyung
    • Journal of the Korean Chemical Society
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    • v.62 no.2
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    • pp.137-147
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    • 2018
  • The purpose of this study was to analysis total number of 123 SSI programs by SSI criteria. The criteria was consisted of subject, school level, starting point, scientific evidence, social content, use of scientific knowledge, level of conflict of interest, and evaluation and reflection. The results of the analysis are as follows. First, elementary school programs were the most and middle school programs were relatively few. Second, starting point was mainly in the actual situation, the fiction and nonfiction situation, and the situation including the controversy and conflict was less than 10%. Third, it was based on scientific evidence but mainly influenced by individual values and perceptions. Fourth, social contents were developed mainly in ethics/morality/value, political/social life/economy, environment contents. Fifth, the use of scientific knowledge mainly consisted of scientific decision making, scientific critical thinking, and information search. However, science inquiry, risk assessment, and cost effectiveness were less than 10%. Scientific inquiry is the essential factor of science education, and one of core competencies of national science curriculum. SSI program should be able to experience various kinds of conflicts, and to evaluate and reflect through reflection.

A Study on the Influence of Job Characteristics and Organizational Justice on the Job Satisfaction - Focusing on the Small- and Medium- Sized Firms in Namdong und Banwool Area - (중소제조업 종업원의 직무특성과 조직 공정성이 직무만족에 미치는 영향 - 남동 및 반월 공단을 중심으로 -)

  • Chang, Sug-In
    • Korean Business Review
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    • v.19 no.2
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    • pp.23-46
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    • 2006
  • In modern economic societies, individuals are governed by organizations and they managed their daily lives in one way or another. through such organizations. All activities of the organizations are carried out by the job performance of individuals. Job is a very important factor for both individuals and organizations. The study is the explore. the effect of job characteristics and organizational characteristics on the job satisfaction in the small- and medium- sized firms in Namdong und Banwool Area. Job characteristics and organizational justice were hypothesized to be positively related to job satisfaction. To examine the influence of job characteristics and organizational justice on job satisfactions, data were collected from 320 employees of the small- and medium- sized manufacturing companies in Namdong und Banwool Area. This research took independent variables as the core job characteristics of the job characteristic theory such as skill variety, job stagnation, job importance, autonomy, feed back, and organizational justice as distributive and procedural justice. As a result, I can make the following suggestions. First, The Results show that job characteristics and organizational justice were significant and important predictors of job satisfaction. Secondarily, to raise the job desire of organizational members, job must be designed in such a way that the members can highly recognize their job characteristics.

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A Study on the Collaborative Partnership Factors between Freight Forwarders and Consignors (국제물류주선업체와 화주기업의 협력적 파트너쉽 요인에 관한 연구)

  • Jun, Kyung Sook;Jang, Hyun Mi;Kim, Sang Youl
    • Journal of Korea Port Economic Association
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    • v.30 no.4
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    • pp.169-198
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    • 2014
  • Due to the recent worldwide economic downturn, companies are required to put more effort into their innovation and quality improvement. In particular, business relationship is increasingly emphasized to be changed from a vertical relationship to a more horizontal relationship, such as collaborative partnership based on trust. In the logistics industry, through the collaboration, consignors can gain competitive advantages by focusing on their core capabilities, and freight forwarders also take advantages of securing stable cargoes and specialist expertise in distribution. Therefore, this study aims to identify key factors for developing a collaborative partnership between freight forwarders and consignors, and further examine the differences between the two groups empirically by using questionnaire survey. Based on the results, the main factors were found as follows: 1) Trust Building, 2) Competence Improvement, 3) Business Ecosystem and 4) Government Assistance. According to the analysis on sub-factors, first, among the four main factors, it turned out that trust is the most important variable. Specifically, the sub-factor of providing regular and stable service was revealed to be most critical. Second, it was found that forwarders need to improve services on 'Information Exchange System' and 'Electronic Data Interchange'. Finally, it is necessary for both consignors and forwarders to have better understanding of partnership. Key implications for both groups are highlighted based on the results.

The Effects of Storytelling Family Classes Using Picture Books on the Resilience and Parent-Child Relationship of Adolescents: Focusing on the Core Concepts of 'Relationship' and 'Safety' in Middle School Technology·Home Economics (그림책을 활용한 스토리텔링 가족 수업이 청소년의 회복탄력성과 부모자녀관계에 미치는 효과: 중학교 기술·가정 '관계'와 '안전'의 핵심개념을 중심으로)

  • Joo, Hyunjung;Choi, Saeeun
    • Journal of Korean Home Economics Education Association
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    • v.32 no.1
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    • pp.167-184
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    • 2020
  • The purpose of this study was to examine the effects of storytelling lessons using picture books on the resilience of adolescents and the parent-child relationships in the family unit of home economics subject in middle school. For this purpose, I selected picture books of five themes on family type, family relationship, family conflict, sexual violence, domestic violence, and family loss, and developed a teaching-learning process plan for 'Family class with picture book' using storytelling elements and techniques. The teaching-learning plan was applied to 194 middle school students in technology·home economics classes, and the learning effet was evaluated by comparing pre- and post-tests. As a result, the resilience level perceived by adolescents increased significantly after class, but no significant effect was found on self-expansion, which is a sub-factor of sociality. In the parent-child relationship of adolescents, the effect of instruction was shown in all areas, and the affectional bonds felt in the relationship with mother than with father showed higher increase. In the family unit of home economics, storytelling lesson through picture book seems to have a positive influence on the adolescents in their relationship with the family by bringing up the potential power in them to stand against the adversities they may face.

A Study on the Relative Weights of the Components of Core Competence Based Learning Outcomes in STEAM (Science, Technology, Engineering Art, Mathematics) (융합인재교육에서 핵심역량 기반 학습성과 구성요소의 상대적 가중치 연구)

  • Park, Ki-Moon
    • 대한공업교육학회지
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    • v.40 no.2
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    • pp.239-258
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    • 2015
  • The purpose of this study is to provide basic data that can be used in a reasonable assessment of the learning outcomes of STEAM. It presented a learning outcome evaluation method, relative weights of key competencies standard that a learner should cultivate. For this study, a pairwise comparison questionnaire about the key competencies was conducted on the STEAM professionals, and AHP was applied to analyze the priority of main factors of key competencies. The results of this study are as follows. First, the importance of capabilities of convergence accomplishment and capabilities of convergent cognition, in the first layer of key competencies, were 39.4% and 36.8%, respectively. In the education evaluation of the STEAM, capabilities of convergence accomplishment and capabilities of convergent cognition showed similar level of importance, and were considered more important factor than capabilities of convergence attitude (23.8%). Second, the relative importance of capabilities of problem solving (20.0%) was highest in the second layer of key competencies, and followed by capabilities of creative thinking (18.3%), responsibility (15.3%), and understanding convergence knowledge (11.0%). Third, it will be a foundation of a competency evaluation, which reasonably evaluates, based on the relative weights, whether to accomplish educational objectives of the STEAM program In addition, this results is expected to become a guide to develop an education program that can improve the teaching and learning process and raise the learning outcome, as well as an education evaluation of the STEAM.

A Study of the Core Factors Influencing the Golfer Satisfaction with Golf Courses in Korea (한국골프장의 이용자 만족도 결정 요인에 관한 연구)

  • Ryu, Chang-Hyun;Kim, Yoo-Il
    • Journal of the Korean Institute of Landscape Architecture
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    • v.36 no.5
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    • pp.26-34
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    • 2008
  • This study was conducted to investigate the correlation between golfer satisfaction and the diverse variables of golf course design and operation from the golfer's point of view. It was intended to reflect the various expectations and desires of golfers regarding golf course design and operation. The study was conducted on 119 golf courses in Korea, and 309 questionnaires were collected and analyzed. Results are summarized as follows. First, the most influential operational service variables on golfer satisfaction were "appearance of the golf courses", followed by "staff service", and "greens fee". Second, the most influential course design and maintenance factor variables on satisfaction were "course maintenance status", "teeing ground characteristics", and "landscape architecture". Third, based on the results shown in these two areas, a linear regression analysis was conducted to synthetically explain "operational service" variables and "course design and maintenance" variables. As a result, it was found that the explanation power of the synthetic model was 36.5%, and a model appropriateness test was found to be positive. As a result of a regression analysis of the synthetic model affecting golfer satisfaction, the most influential factors were "course maintenance status" followed by "landscape architecture", "tee characteristics", and "staff service". Regarding coefficient values, course maintenance status had an influence of 21.8% followed by landscape architecture at 20%, tee characteristics at 17.7%, and staff service at 15.5%. These results were found to be different from preceding studies that emphasized golf course operational service.

Aesthetic elements in Product Design of Korean and Chinese's Consumer preference (한국.중국 소비자 선호 제품디자인의 심미성 요소 연구)

  • Jeong, Su-Kyoung;Hong, Jung-Pyo
    • Archives of design research
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    • v.19 no.2 s.64
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    • pp.63-72
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    • 2006
  • The design in modern industrial society is the core of corporate administrational strategy and a factor that determines the competitiveness of a country. And the process of purchasing products is the matter related to the awareness of design which expresses the desire to own the design product that consumers prefer, implying that the aesthetic feature of product has become a critical characteristics of product design rather than the technical function of product. In this regard, the development of product design with a new dimension is urgently called for, by analyzing and shedding light on the aesthetic features of factors related to the preference of consumers. This study considers the preceding studies on the aesthetic factors and the reaction of customers to the product design to figure out the importance of factors related to the preference of customers, in an effort to shed light on the aesthetic factors that affect the customers' preference of product and the evaluation of product. In addition to that, this study investigated the preference that Korean and Chinese customers display toward the product and assessed the aesthetic features of preferred product in order to come to the conclusion from the experiment and analysis on how much effect the aesthetic factors and the aesthetic factors by product have on the preference of customers. Therefore, this study tries to propose the data that can be useful for the design of product targeted for consumers in Korea and China, by shedding light on what aesthetic factors that products preferred by consumers in Korea and China have and how much effect such factors have on the preference of consumers in an attempt to provide the guideline on the aesthetic factors of the product design.

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Research of a plan setting Secondary School Teacher Recruitment Test of Electricity·Electronics·Communication Subject (중등교사 임용시험 전기·전자·통신 과목의 출제방안 연구)

  • kim, Jinsu;Rho, Taechun;Ryu, BungRho;Eun, Taeuk
    • 대한공업교육학회지
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    • v.31 no.2
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    • pp.128-154
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    • 2006
  • In the knowledge-based society, the quality of education is the core factor of national development. Above all, for improving educational quality, it is important to advance teacher's quality. Therefore, in order to maintaining high-level quality of education, it is required to select and appoint competent teacher. It deserves emphasis on importance of teacher recruitment test for maintaining high-level quality of education in this changes of age. Specially, Secondary School Teacher Recruitment Test of Electricity Electronics Communication Subject is declined qualitatively as each Subject of Electricity Electronics Communication is integrated and criterion of examination is obscured. This research analyzed The seventh curriculum and curriculum of Institution of Teacher Education of Electricity Electronics Communication Subject and already known examination of it On the basis of analyzing result, A field, proportion and points of examination decided through a expert conference are as follow: first, Teacher Recruitment Test of Electricity Electronics Communication Subject consists of subject pedagogics and contents. a proportion of subject pedagogics is 20% and subject contents is 80%. second, a subfield of subject contents consists of industrial education, industrial curriculum, industrial instruction method, practical guidance method, management of practical field organization, assesment of industrial education, industrial-educational cooperation and vocation and career education. third, subject contents consists of a common special, foundation special and application special field. a common a proportion of special field is 7.4%, foundation special is 20% and application special field which consists of electric field(21.3%), electronic field(21.3%) and communication field(10%) is 52.6%. fourth, Teacher Recruitment Test of Electricity Electronics Communication Subject execute practical technique test after finishing writing test.