• Journal of Life Science
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• v.22 no.8
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• pp.999-1008
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• 2012

The circadian clock is a self-sustaining 24-hour timekeeper that allows organisms to anticipate daily-changing environmental time cues. Circadian clock genes are regulated by a transcriptional-translational feedback loop. In Arabidopsis, LATE ELONGATED HYPOCOTYL (LHY) and CIRCADIAN CLOCK-ASSOCIATED 1 (CCA1) transcripts are highly expressed in the morning. Translated LHY and CCA1 proteins repress the expression of the TIMING OF CAB EXPRESSION 1 (TOC1) transcripts, which peaks in the evening. The TOC1 protein elevates the expression of the LHY and CCA1 transcripts, forming a negative feedback loop that is believed to constitute the oscillatory mechanism of the clock. In mammals, the transcription factor protein CLOCK, which is a central component of the circadian clock, was reported to have an intrinsic histone acetyltransferase (HAT) activity, suggesting that histone acetylation is important for core clock mechanisms. However, little is known about the components necessary for the histone acetylation of the Arabidopsis clock-related genes. Here, I report that DET1 (De-Etiolated1) functions as a negative regulator of a key component of the Arabidopsis circadian clock gene LHY in constant dark phases (DD) and is required for the down-regulation of LHY expression through the acetylation of histone 3 (H3Ac). However, the HATs directly responsible for the acetylation of H3 within LHY chromatin need to be identified, and a link connecting the HATs and DET1 protein is still absent.

• Information Systems Review
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• v.4 no.2
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• pp.209-222
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• 2002

EDI (Electronic Data Interchange) has been widely utilized to support Business Activities since it has such advantages as fast transfer of information, less documentation work, efficient information exchange etc. Recently e-business environment has urged the traditional EDI system to be changed to ebXML framework. To apply the ebXML framework to a certain industry, it is required to implement Business Process (BP), Core Component (CC), Collaboration Protocol Profile (CPP), Collaboration Protocol Agreement (CPA), Messaging system etc. We have selected the port and logistics industry as a target domain to apply ebXML framework, since the EDI usage ratio of it is relatively higher than other industries. In this paper, we have analyzed the current status of EDI system and transaction processes in the port and logistics industry. We have defined the business process that will be registered in the registry/repository, the main component of ebXML framework, using UN/CEFACT modeling methodology. And Business Collaborations, Business Transactions, Business Document Flows, Choreography, Pattern, etc. are represented using UML according to UN/ CEFACT modeling methodology, to apply ebXML Framework to the port and logistics distribution industry. Also we have suggested the meta methodology for applying the ebXML framework to other industries.

• Korean Journal of Microbiology
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• v.46 no.2
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• pp.223-227
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• 2010

RNase E plays a major role in the degradation and processing of a large number of RNA transcripts in Escherichia coli and forms the core component of the degradosome, a large protein complex involved in RNA metabolism. RraA and RraB are recently discovered protein inhibitors of RNase E and are evolutionarily conserved. In this study, we observed that, unlike RraA, overexpression of RraB did not rescue growth arrest of E. coli cells overexpressing RNase E. To examine whether this phenomenon stems from differential inhibitory effects of RraA and RraB on RNase E substrates, we analyzed three in vivo RNase E substrates. The results showed that RraA inhibited RNase E activity more efficiently than RraB on the degradation of RNA I, which controls the copy number of ColE1-type plasmid, and rpsO mRNA encoding ribosomal protein S15, while RraB was unable to inhibit the processing of pM1 RNA, a precursor of the RNA component of RNase P, by RNase E. Our results imply that RraB inhibits RNase E activity in a more substrate-dependent manner than RraA and this property of RraB may explain why overexpression of RraB could not rescue cells overexpressing RNase E from growth arrest.

• Journal of KIISE:Computing Practices and Letters
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• v.10 no.6
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• pp.472-483
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• 2004

Many metadata registry management systems have been developed, which are based on ISO/IEC ll179. However, they do not follow the international standard, ISO/IEC ll179 nor provide some of mandatory functions. It is difficult to a develop metadata registry management system for domestic environment because of their hidden implementations. The goals of this paper are to solve the problems of the existing systems and to develop a metadata registry management systems for accumulation of primitive technologies. This paper also shows the metadata registry building process for the science and technology information field using the developed system. This system consists of Metadata Registry Layer, Core Component Layer, Extension Layer, and Service Interface Layer. The developed metadata registry management system follows ISO/IEC ll179 and contains mandatory functions for practical use. Therefore, it can be used as a guideline for building metadata registries and a development process of metadata registry management systems. We can easily reuse its components for development of metadata registry management systems in various fields because the system is designed and implemented based on the component-based development methodology. It also decreases time and cost for developing systems.

• Journal of Korea Technology Innovation Society
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• v.22 no.3
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• pp.362-381
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• 2019

The purpose of this study is to examine how two factors among various affecting factors of technological innovation, i.e. sectoral system of innovation and R&D support service, were actually applied in the case of NUC Electronics. This company has achieved high level of innovation performance through change of injection port and improvement of extracting rate. This was possible because each component of sectoral system of innovation system was matched with the innovation activity. The improvement of the performance in NUC Electronics was attributable to its own innovation efforts and R&D support service of government research institute. In the process of technological innovation, the company could receive high-level services in areas such as product design and virtual experiments that companies can not solve themselves. It can be said that the role of government and public institutions to support the shortage of SMEs was important. In terms of each component of sectoral system of innovation, we found that there were many opportunities of new technology; sustainability was low; imitation was easy; appropriability was low but it has dualily; accumulation of technology was relatively high, availability of external knowledge was high. At the same time, both of the company and the network played an important role, and market conditions were very favorable. In terms of R&D support services, it is a direct effect that a great deal of time and cost savings have been achieved through virtual experiments on the material and shape of the screw. As an indirect effect, the core competence of the company has been greatly strengthened by utilizing the momentum of technology development through external support, hence the company could establish the structure of virtuous circle of innovation.

• Economic and Environmental Geology
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• v.52 no.1
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• pp.65-79
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• 2019

In this study, simple regression and multiple regression analyses were performed to analyze the relationship between breccia and clay content and shear strength in fault cores. The results of the simple regression analysis performed for each rock (andesitic rock, granite, and sedimentary rock) and three levels of normal stress (${\sigma}_n=54$, 108, 162 kPa), reveal that the shear strength is proportional to breccia content and inversely proportional to clay content. Furthermore, as normal stress increases, the shear strength is influenced by the change in component content, correlating more strongly with clay content than with breccia content. In the multiple regression analysis, which considers both breccia and clay content, the shear strength is found to be more sensitive to the change in breccia content than to that of clay. As a result, the most suitable regression model for each rock is proposed by comparing the coefficients of determination ($R^2$) estimated from the simple regression analysis with those from the multiple regression analysis. The proposed models show high coefficients of determination of $R^2=0.624-0.830$.

• Journal of the Korea Convergence Society
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• v.12 no.5
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• pp.191-196
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• 2021

This paper proposes to strengthen the technological capabilities of small and medium enterprises on the establishment of a component standardization system and the localization of parts, which is the basis of the marine wind industry. The wind industry is a natural energy industry that countries around the world are paying attention to, and continues to invest and research and development. In particular, most companies are focusing on research and investment in component development, the smallest unit. Therefore, it is believed that we should focus on the three most fundamental and underlying wind industry, an eco-friendly energy industry that could determine the fate of the nation in the future. First, an understanding of the roadmap for standardization should be prioritized. Second, it is necessary to establish a domestic standardization of international standards according to domestic conditions. Third, localization of high value-added single products and components should be achieved by lowering dependence on overseas imports. In the future, it is hoped that the wind industry, centered on small and medium-sized enterprises, will become a solid-based national industry and be completed as a national infrastructure leading the global wind market.

• Journal of Advanced Navigation Technology
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• v.11 no.3
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• pp.259-265
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• 2007

Systematic components for implementing ubiquitous computing, for example, electronic devices, electric home appliances, and controllers, etc, are consist of not only circuits but also softwares expected to do some special system-controlling functions, and these softwares used to be called like as embedded software. Because embedded software is a core component controlling systems, the codes or control flows should be protected from being opened to the public or modified. Embedded software security can be divided into 2 parts: first is the unauthorized access to development site and embedded software, second is the unauthorized disclosure or modification. And this research is related to the first aspect of them.This paper proposes some security check requirements related to embedded software development site by analyzing the ALC_DVS.1 of the ISO/IEC 15408 and Base Practices (BPs) of the ISO/IEC 21827. By applying this research, we expect to protect unauthorized modification of embedded software indirectly.

• The Journal of Society for e-Business Studies
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• v.8 no.3
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• pp.87-105
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• 2003

Business Process Management (BPM) is an emerging trend of managing business process life cycles and integrating heterogeneous systems . Recently, BPM is considered as an essential element for automation of complex business processes involving many companies, particularly for those in an e-Business environment. In such an environment, it is very important for each business partner to trace history of resources. However, it has been a difficult problem for Workflow Management Systems(WFMSs) to support management of resource changes because of limited storage, complex process structure, and absence of formal change model. In this paper. a new framework is proposed, which can support change management for documents, one of core resources of business process. Under a traditional WFMSs framework, all workflow components belong to either build-time or run-time function, and executions of workflow processes are performed by the two functions . To manage changes of documents while process executing. a new framework with additional component modules are required. A version control method is introduced for the purpose of managing document changes. The proposed method includes five models for document structure, process structure, association between process and document, version management, and efficient version storage. A prototype system is developed to demonstrate the effectiveness of the proposed models.

• Journal of Distribution Science
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• v.16 no.12
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• pp.57-68
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• 2018

Purpose - The development of technologies lead the volume of sale on online market increase but an off-line shopping center is still a core component in the omni-channel strategy. It is generally thought that high-level retailtainment on brick and mortar store affects purchase intentions positively, but some previous studies dispute that and have reported that retailtainment does not affect purchase intentions. So we have studied the additional factors' effect - the nature of purchase and utility - with retailtainment. Research design, data, and methodology - There are 8 treatment groups which were assigned by the method of retailtainment (high vs. low), nature of purchase (essential vs. non-essential), and utility (acquisition vs. transaction). A total of 240 subjects (office workers = 163, 68%; undergraduates = 77, 32%; average age = 30s; female = 39%) were divided into groups and exposed to one of the eight scenarios. Participant's purchase intention was the dependent, and ANOVA and L-matrix were used to analyze for main and interactive effects between factors. Results - First, the main effect and interactive effect between retailtainment and the nature of purchase are significant. We also found that the contrast between essential and non-essential at low-level retailtainment is higher than that of high-level retailtainment. Second, in the case of retailtainment and utility, transaction utility under high-level retailtainment affects purchase intentions positively. Third, between the nature of the purchase and utility, the main effect of the nature of purchase and the interactive effect is significant, but the main effect of utility is not significant. In the case of non-essential goods, the purchase intention was high when transaction utility was provided but in the case of essential goods, acquisition utility increased purchase intentions. Finally, when transaction utility is given, purchase intentions of essential goods increase under low retailtainment, and the purchase intentions of non-essential goods increase under high retailtainment. Conclusions - When customers buy essential goods, discounts decrease purchase intentions. During the season for bargain sales, purchase intentions increase when retailtainment of essential goods is low, and retailtainment of non-essential goods is high.