• Journal of Microbiology and Biotechnology
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• 제31권3호
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• pp.358-367
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• 2021

The World Health Organization (WHO) has declared the coronavirus disease 2019 (COVID-19) as an international health emergency. Current diagnostic tests are based on the reverse transcription-quantitative polymerase chain reaction (RT-qPCR) method, which is the gold standard test that involves the amplification of viral RNA. However, the RT-qPCR assay has limitations in terms of sensitivity and quantification. In this study, we tested both qPCR and droplet digital PCR (ddPCR) to detect low amounts of viral RNA. The cycle threshold (CT) of the viral RNA by RT-PCR significantly varied according to the sequences of the primer and probe sets with in vitro transcript (IVT) RNA or viral RNA as templates, whereas the copy number of the viral RNA by ddPCR was effectively quantified with IVT RNA, cultured viral RNA, and RNA from clinical samples. Furthermore, the clinical samples were assayed via both methods, and the sensitivity of the ddPCR was determined to be equal to or more than that of the RT-qPCR. However, the ddPCR assay is more suitable for determining the copy number of reference materials. These findings suggest that the qPCR assay with the ddPCR defined reference materials could be used as a highly sensitive and compatible diagnostic method for viral RNA detection.

• Journal of Ginseng Research
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• 제44권3호
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• pp.399-404
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• 2020

Korean ginseng (Panax ginseng) is associated with a variety of therapeutic effects, including antioxidative, anti-inflammatory, vasorelaxative, antiallergic, antidiabetic, and anticancer effects. Accordingly, the use of ginseng has reached an all-time high among members of the general public. However, the safety and efficacy of ginseng in transplant recipients receiving immunosuppressant drugs have still not been elucidated. Transplantation is the most challenging and complex of surgical procedures and may require causation for the use of ginseng. In this regard, we have previously examined the safety, immunological benefits, and protective mechanisms of ginseng with respect to calcineurin inhibitor-based immunosuppression, which is the most widely used regimen in organ transplantation. Using an experimental model of calcineurin inhibitor-induced organ injury, we found that ginseng does not affect drug levels in the peripheral blood and tissue, favorably regulates immune response, and protects against calcineurin inhibitor-induced nephrotoxicity and pancreatic islet injury. On the basis of our experimental studies and a review of the related literature, we propose that ginseng may provide benefits in organ transplant recipients administered calcineurin inhibitors. Through the present review, we aimed to briefly discuss our current understanding of the therapeutic benefits of ginseng related to transplant patient survival.

• 대한안전경영과학회:학술대회논문집
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• 대한안전경영과학회 2011년도 추계학술대회
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• pp.219-224
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• 2011

The research reviews the logical approach based on the creative thoughts. The two logical approaches, including deductive convergent and inductive divergent are discussed with why-why techniques and how-how techniques. While the deductive thinking is vertical logic for interconnected hierarchical and deep domains, the inducive thinking is horizontal logic for mutually exclusive and collectively exhausted frameworks. The creative thinking comes from the reversing the logic and lessening the premise of convergent and divergent approaches.

• 경영과학
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• 제25권3호
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• pp.101-122
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• 2008

A wide variety of convergent digital products are emerging through the combination of multiple independent digital technologies. Digital convergence provides new revenue sources for businesses and new ways of satisfying individual needs of consumers. Despite its business and consumer implications, little research has addressed how people perceive or evaluate convergent products. This study aims at understanding how consumers interpret and evaluate convergent digital products by conducting two consecutive studies. Firstly, a survey was conducted to understand how people interpret convergent products in three ways suggested by the conceptual combination theory based in cognitive science. Secondly, an experiment was conducted to investigate the impact of combination strategies and product similarities on user evaluation of convergent products. Study results indicate that similarity of constituent products has a substantial effect on the interpretation of concept combination strategies. Moreover, combination strategy and product similarity were found to have substantial effects on user comprehension, perceived newness, and preferences for convergent products. This paper ends with an examination of the implications and limitations of the study results.

• 공업화학
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• 제32권1호
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• pp.42-48
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• 2021

본 연구에서는 열분해 연료유를 이용하여 석유계 피치 기반 활성탄을 제조하였고, 이를 활용하여 일산화질소 가스 검출 센서를 개발하였다. 피치의 분자량 증가를 위해 피치 합성 시 중합 반응을 촉진시키는 폴리에틸렌 테레프탈레이트를 첨가하였다. 피치의 분자량 증가는 피치 기반 활성탄의 비표면적 및 미세기공 부피 증가에 기여하였고, 이는 활성탄 기반 센서의 일산화질소 가스 검출 특성 향상시켰다. 또한 테레프탈레이트 첨가 피치를 사용할 때 활성탄의 표면 산소 관능기 및 전도성 변화를 확인하고 테레프탈레이트 첨가가 활성탄의 물성 및 일산화질소 가스 검출 특성에 미치는 영향을 분석하였다.

• 한국전기전자재료학회논문지
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• 제20권5호
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• pp.467-470
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• 2007

Application field of neutron beam is very broad including industry, medicine and science. But the research and development and use of neutron beam is restricted within in narrow limits in this country, because neutron beam facility is insufficient - a big research facility of nuclear reactor(HANARO) and some small industrial facilities which use radioisotope neutron source are available. This paper compare and investigate the results of experiment and numerical analysis of the discharge in the spherically convergent beam fusion device which were expected as a portable neutron source. The spherically convergent beam fusion device will offer stability in neutron production, possibility of movement for convenience, low construction cost and higher neutron flux than radioisotope neutron source. The star mode discharge which efficiently generate neutron, were observed at both results.

• 한국경영과학회지
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• 제20권2호
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• pp.125-137
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• 1995

This paper provides a locally convergent algorithm and a globally convergent algorithm for a variational inequality problem over convex polyhedral. The algorithm are based on the B (ouligand)-differentiability of the solution of a nonsmooth equation derived from the variational in-equality problem. Convergences of the algorithms are achieved by the results of Pang[3].

• 한국콘텐츠학회논문지
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• 제12권12호
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• pp.605-615
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• 2012

무용학은 태생적으로 융복합의 성격을 띄고 있다. 그동안의 무용학은 타학문 영역의 이론을 수용하여 예술이론으로만은 설명할 수 없는 무용현상을 다각도에서 이론적으로 규명해나가면서 무용학 영역을 확장해왔다. 그러나 디지털 혁명에 따른 테크늄과 인터렉션 그리고 자유와 개방이라는 융합사회의 특성을 종전의 무용학만으로 설명하기에는 역부족이다. 이에 국내 무용학의 융복합 연구동향을 고찰한 결과, 2000년대에 들어서면서 무용학은 1.다양한 영역의 융복합 무용학 연구 촉발, 2.융복합 프로그램 개발 연구 시도, 3.무용디지털콘텐츠 융복합 연구 활성화, 4.융복합 무용공연예술현상 연구 이상, 네 측면에서 각 영역이 개별적이긴 하지만 지속적으로 연구가 진행되어 왔음을 알 수 있었다. 이는 무용예술의 기술융합 및 과학분야와 학제간 융복합 연구 그리고 타 학문영역과 통섭연구라는 측면에서 무용학의 영역확장 및 구조변화를 일으킬 수 있는 촉진제 역할을 하고 있었다. 그러나 문제점은 현재 연구개발안이나 연구프로그램은 무용디지털콘텐츠 융합 연구이외에는, 거의 대부분 현실화되거나 실용화되는 경우가 없었다. 이에 융합시대에 따른 무용학 발전을 위하여 다음 세 가지 결론을 도출했다. 첫째, 과학과 무용과 기술 이론이 집약된 무용융합학을 제안한다. 이는 융합사회에 따른 새로운 인문학적 모델을 제시할 수 있는 학문적 토대를 마련해 줄 수 있다. 둘째, 무용학의 학제적 융합연구가 현실에서 실효성을 거둘 수 있도록 이론을 현장에 상용화하는 행동주의적 단계로 이행해야 한다. 섯째, 무용융합공연의 연구기술 축적 및 활성화를 위해 대규모 위주의 융합공연 형태에서 아이디어가 참신한 소규모 융합공연 형태로 전환이 필요하다.

• 한국감성과학회:학술대회논문집
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• 한국감성과학회 2007년도 춘계학술대회 및 국제감성 심포지엄
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• pp.67-69
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• 2007

Customary way of thinking may be the most major stumbling block to creative thinking in basic design education in the information and network era. The basic design education was used to be based on personal experience or subjective ideas, but these days, the role of divergent thinking and convergent thinking which provide the basis of creative techniques has been closely examined. Going beyond a divergent thinking and directly starting a convergent thinking means bypassing the design process of the existing basic design education. Though preceding studies considered various creative techniques apart from divergent thinking and convergent thinking, this study presumed that complementing the most typical methods of divergent thinking and convergent thinking may result in the same basic design education effect. So, what approach must be used to the design? The way of thinking needs to change. For that, we try to apply the mapping to basic design education. It must encompass interactive thinking which includes immaterial elements and communication. Divergent thinking can begin with the accurate understanding of current state, and the created current state resolves the design process that needs to be a certain thing. The purpose of this study was to present the method for applying the mapping techniques to basic design education based on divergent and convergent thinking which provides the basis of creative ideas.

• 대기
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• 제25권1호
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• pp.51-66
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• 2015

This study was conducted to perform various sensitivity experiments using WRF (Weather Research and Forecasting) model in order to determine the effects of terrains of the Korean Peninsula and the land-sea thermal contrast on the formation and development of the convergent cloud band for the cases of 1 February 2012. The sensitivity experiments consist of the following five ones: CNTL experiment (control experiment), and TMBT experiment, BDMT experiment and ALL experiment that set the terrain altitude of Taeback Mountains and Northern mountain complex as zero, respectively, and the altitude of the above-mentioned two mountains as zero, and LANDSEA experiment that set to change the Korean Peninsula into sea in order to find out the land-sea thermal contrast effect. These experiment results showed that a cold air current stemming from the Siberian high pressure met the group of northern mountains with high topography altitude and was separated into two air currents. These two separated air currents met each other again on the Middle and Northern East Sea, downstream of the group of northern mountains and converged finally, creating the convergent cloud band. And these experiments suggested that the convergent cloud band located on the Middle and Northern East Sea, and the cloud band lying on the southern East sea to the coastal waters of the Japanese Island facing the East Sea, were generated and developed by different dynamical mechanisms. Also it was found that the topography of Taeback Mountains created a warm air advection region due to temperature rise by adiabatic compression near the coastal waters of Yeongdong Region, downstream of the mountains. In conclusion, these experiment results clearly showed that the most essential factor having an effect on the generation and development of the convergent cloud band was the topography effect of the northern mountain complex, and that the land-sea thermal contrast effect was insignificant.