• Journal of the Korea Convergence Society
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• v.10 no.10
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• pp.67-74
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• 2019

The purpose of this study was to determine whether changes of position might effect the convergence pulmonary function of the 20s men of mild intellectual disabilities with obesity. Ten subjects of mild intellectual disabilities with obesity(fat group) and ten contrary subjects without obesity(control group) were participated in the experiment. Subjects were assessed for their pulmonary function by using Fit mate according to the position changes(supine position, 45 lean sitting position, 90 sitting position). One-way repeated ANOVA analyzed each region data of pulmonary function of both the fat group and the control group according to their position changes. The result of the experiment showed that the 20s men of mild intellectual disabilities with obesity have lower pulmonary function than the contrary subjects in the each given posture. In comparison with three experimental positions, supine position was the lowest in the pulmonary function. This study showed the 20s men of mild intellectual disabilities with obesity have lower function of pulmonary volume than the control group, and thus, it suggests that the pulmonary functional data of 20s men of mild intellectual disabilities with obesity in this experiment can be used as a basic respiratory one for the various exercise programs in the area of the physical activities.

• Journal of the Korea Convergence Society
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• v.12 no.8
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• pp.77-83
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• 2021

The purpose of this study was to determine whether the convergence pulmonary function of the 20s men of mild intellectual disabilities with obesity to tredmill exercise. Ten subjects of mild intellectual disabilities with obesity(experimentals) and ten contrary subjects(controls) were participated in the experiment. experimental group conducted treadmill gait training and control group conducted automed exercise. Subjects were assessed for their respiratory function by using Fit mate. The result of the experiments showed high pulmonary function than the controls. Thus, it suggests that the respiratory functional data of 20s men of mild intellectual disabilities with obesity can be used as a various respiratory one for the exercise programs in the area.

• Journal of the Korea Convergence Society
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• v.10 no.12
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• pp.169-175
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• 2019

The purpose of this study was to determine whether changes of multiple lying position might effect the convergence pulmonary function of the 20s men of mild intellectual disabilities. Twenty subjects of mild intellectual disabilities were participated in the experiment. Subjects were assessed for vital capacity by using Fit mate according to the multiple lying position changes(supine position, right sidelying position, left sidelying position, prone position). One-way repeated ANOVA analyzed each region data of vital capacity of subjects according to their multiple lying position. The result of the experiment showed that the 20s men of mild intellectual disabilities have more higher vital capacity to right sidelying position than another lying position. This study suggests that the pulmonary functional data of 20s men of mild intellectual disabilities in this experiment can be used as a basic respiratory one for the bed exercise programs in the area of the physical activities.

• Journal of the Korea Convergence Society
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• v.10 no.6
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• pp.95-101
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• 2019

The purpose of this study was to determine whether PNF respiratory convergence exercise increases the pulmonary function of normal adults by $45^{\circ}$ leaning sitting position. Twenty normal adults in their 20s were randomly assigned to an experimental group (n=10) or control group (n=10). Over the course of four weeks, the experimental group participated in PNF respiration exercises by $45^{\circ}$ leaning position for 30 minutes three per week. And the control group participated in PNF respiration exercises by supine position for 30 minutes three times per week. Subjects were assessed pre-test and post-test by measurement of pulmonary function. Our findings show that the experimental group had significant improvements in expiratoy reserve volume and vital capacity, maximal voluntary volume. In this study, the experimental group showed greater improvement in pulmonary function than the control group, which indicates that the PNF respiratory exercise by $45^{\circ}$ leaning sitting position is effective at increasing the pulmonary function of normal adults.

• Journal of Convergence for Information Technology
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• v.10 no.2
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• pp.176-183
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• 2020

The purpose of this study was to determine whether abdominal pressure belt has an immediate effect on pulmonary function, balance and gait ability for stroke patients. Twenty subjects measured pulmonary function and the COP, BBS, TUG, 10m walk test, and FGA prior to belt wearing. Immediately all subjects were post-tested after wearing abdominal pressure belt of elastic components. Except for forced vital capacity (FVC) and forced experimental volume in the 1 second (FEV1), there were significant differences after belt wearing. This study suggests that the application of abdominal pressure belt enhanced balance and gait ability. However, improving pulmonary function requires several efforts, such as changing the pressure level, posture.

• Korean Journal of Radiology
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• v.20 no.4
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• pp.683-692
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• 2019

Objective: We aimed to evaluate correlations between computed tomography (CT) parameters and pulmonary function test (PFT) parameters according to disease severity in patients with chronic obstructive pulmonary disease (COPD), and to determine whether CT parameters can be used to predict PFT indices. Materials and Methods: A total of 370 patients with COPD were grouped based on disease severity according to the Global Initiative for Chronic Obstructive Lung Disease (GOLD) I-IV criteria. Emphysema index (EI), air-trapping index, and airway parameters such as the square root of wall area of a hypothetical airway with an internal perimeter of 10 mm (Pi10) were measured using automatic segmentation software. Clinical characteristics including PFT results and quantitative CT parameters according to GOLD criteria were compared using ANOVA. The correlations between CT parameters and PFT indices, including the ratio of forced expiratory volume in one second to forced vital capacity (FEV1/FVC) and FEV₁, were assessed. To evaluate whether CT parameters can be used to predict PFT indices, multiple linear regression analyses were performed for all patients, Group 1 (GOLD I and II), and Group 2 (GOLD III and IV). Results: Pulmonary function deteriorated with increase in disease severity according to the GOLD criteria (p < 0.001). Parenchymal attenuation parameters were significantly worse in patients with higher GOLD stages (P < 0.001), and Pi10 was highest for patients with GOLD III (4.41 ± 0.94 mm). Airway parameters were nonlinearly correlated with PFT results, and Pi10 demonstrated mild correlation with FEV1/FVC in patients with GOLD II and III (r = 0.16, p = 0.06 and r = 0.21, p = 0.04, respectively). Parenchymal attenuation parameters, airway parameters, EI, and Pi10 were identified as predictors of FEV₁/FVC for the entire study sample and for Group 1 (R² = 0.38 and 0.22, respectively; p < 0.001). However, only parenchymal attenuation parameter, EI, was identified as a predictor of FEV₁/FVC for Group 2 (R² = 0.37, p < 0.001). Similar results were obtained for FEV₁. Conclusion: Airway and parenchymal attenuation parameters are independent predictors of pulmonary function in patients with mild COPD, whereas parenchymal attenuation parameters are dominant independent predictors of pulmonary function in patients with severe COPD.

• Journal of the Korea Society of Computer and Information
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• v.26 no.12
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• pp.61-67
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• 2021

In this paper, we propose a method of extracting and recognizing related information for research from images of the unstructured pulmonary function test papers using character detection and recognition techniques. Also, we develop a post-processing method to reduce the character recognition error rate. The proposed structuring method uses a character detection model for the pulmonary function test paper images to detect all characters in the test paper and passes the detected character image through the character recognition model to obtain a string. The obtained string is reviewed for validity using string matching and structuring is completed. We confirm that our proposed structuring system is a more efficient and stable method than the structuring method through manual work of professionals because our system's error rate is within about 1% and the processing speed per pulmonary function test paper is within 2 seconds.

• Biomolecules & Therapeutics
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• v.28 no.3
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• pp.250-258
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• 2020

Emphysema, a major component of chronic obstructive pulmonary disease (COPD), is a leading cause of human death worldwide. The progressive deterioration of lung function that occurs in the disease is caused by chronic inflammation of the airway and destruction of the lung parenchyma. Despite the main impact of inflammation on the pathogenesis of emphysema, current therapeutic regimens mainly offer symptomatic relief and preservation of lung function with little therapeutic impact. In the present study, we aimed to discover novel therapeutics that suppress the pathogenesis of emphysema. Here, we show that LJ-2698, a novel and highly selective antagonist of the adenosine A₃ receptor, a G protein-coupled receptor involved in various inflammatory diseases, significantly reversed the elastase-induced destructive changes in murine lungs. We found that LJ-2698 significantly prevented elastase-induced airspace enlargement, resulting in restoration of pulmonary function without causing any obvious changes in body weight in mice. LJ-2698 was found to inhibit matrix metalloproteinase activity and pulmonary cell apoptosis in the murine lung. LJ-2698 treatment induced increases in anti-inflammatory cytokines in macrophages at doses that displayed no significant cytotoxicity in normal cell lines derived from various organs. Treatment with LJ-2698 significantly increased the number of anti-inflammatory M2 macrophages in the lungs. These results implicate the adenosine A₃ receptor in the pathogenesis of emphysema. Our findings also demonstrate the potential of LJ-2698 as a novel therapeutic/preventive agent in suppressing disease development with limited toxicity.

• Journal of the Korea Convergence Society
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• v.5 no.4
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• pp.61-68
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• 2014

In the present study, we aimed to examine the effects of Schroth exercise(three-dimensional convergence exercise) on pulmonary function(vital capacity, and chest expansion), Cobb's angle, scoliometer angle, and erector spinae muscle activity. We examined 40 students with idiopathic scoliosis(Cobb's angle $10^{\circ}$). They were divided into the Schroth and conventional exercise groups, with 20 people in each group. Statistical analysis was performed by using SPSS 18.0 with a paired t-test(pre-post difference) and an independent t-test(between-group differnence). the result of were as follows; 1) After 8 weeks of Schroth exercise, significant improvements were observed in Cobb's angle, rib hump, vital capacity, chest expansion, and right thoracic longissimus muscle activity. 2) After 8 weeks of conventional exercise, a significant improvement was observed only in chest expansion. These findings indicate that the Schroth exercise program improved the Cobb's angle, rib hump, pulmonary function, and sEMG results. Therefore, this study demonstrates the usefulness of the Schroth exercise program for idiopathic scoliosis.

• Journal of Convergence for Information Technology
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• v.11 no.7
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• pp.164-171
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• 2021

This study analyzed the post-exercise cardiopulmonary function, maximal oxygen uptake, heart rate and recovery time through smoker's short - term smoking cessation and trunk stabilization exercise for 72 hours. We analyzed the effect of trunk stabilization exercise on the cardiopulmonary function of smokers and non-smokers. As a result, it was found that both smokers and non-smokers groups showed significant changes in pulmonary function (FVC, SVV, MVV), maximal oxygen uptake, recovery time Difference. This suggests that the trunk stabilization exercise may have a positive effect on the cardiopulmonary function of short-term non-smokers as well as non-smokers for a short period of time, and a more stable and effective method for preventing and improving the reduction of cardiorespiratory function