• KSBB Journal
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• 제18권2호
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• pp.155-160
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• 2003

Streptoverticillium morbaraene로부터 미생물 유래 transglutaminase 생산을 위하여 최적의 용존산소 농도를 구명하였다. 용존산소는 용존산소 농도 자동 조절 시스템에 의해 조절되었다. 발효 중 용존산소 농도 조절을 위하여 통기속도는 0.3-3.9 L/min, 교반속도는 260-360 rpm으로 각각 범위를 설정하였다. 용존산소 농도를 조절한 다양한 회분식 배양에서 용존산소가 20%일 때 최대 미생물유래 transgiutaminase 생산이 가능하였다. 최분배양에서 용존산소 농도를 20%로 조절한 경우 미생물유래 transglutaminase 생산은 2.12 U/mL이었고, 용존산소를 조절하지 않은 회분식 배양의 미생물유래 transglutaminase 생산보다 1.1배 향상되었다. 역시 가장 높은 미생물유래 transglutaminase 생산은 용존산소를 20%로 조절한 유가식 배양에서 가능하였으며, 용존산소를 조절하지 않은 회분식 배양의 미생물유래 transglutaminase 생산에 비교해서 1.3배 증가하였다. 최대 건조균체량과 미생물유래 transglutaminase 생산은 각각 13.2 g/L와 2.6 U/mL이었다. 용존산소를 20%로 용존산소 농도 자동 조절 시스템에 의해 조절한 유가식 배양은 미생물유래 transgiutaminase 생산에 적절하였으며 다른 미생물 배양에도 적용할 수 있을 것으로 판단된다.

• 한국식품과학회지
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• 제13권1호
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• pp.25-29
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• 1981

생아스파라가스의 저장기간을 연장하기 위하여, 아스파라가스(Viking variety)를 정상대기 저장과 C.A. 저장을 하였다. 이때, 밑부분을 물에 담근것과 물에 담그지 않은 것으로 나누어 처리하였다. CA저장은 아스파라가스의 경우 박테리아에 의한 무름병이 발생하는 것을 현저하게 감소시켰으며, 밑부분을 물에 담그어 CA저장을 한결과 무름병 없이 3주일이나 저장할 수 있었다. 섬유질의 분석과 인스트론(Instron)을 이용하여 저장한 아스파라가스의 조직변화를 관찰하였는바, 저장기간이 늘어남에 따라 차츰 질겨지는 것을 볼 수 있었다. 아스파라가스의 섬유질함량은 CA저장에 의하여 그 증가폭이 훨씬 둔화되었고, 밑 부분을 담그어 CA저장을 한 경우 섬유질이 양은 줄어드는 것으로 나타났다. CA 저장에 의한 경우 정상 대기 저장에 비하여 아스파라가스 중의 엽록소 파괴는 훨씬 적게 나타났으며, Reflectance color value와 엽록소 양과는 서로 유의성 있는 상관관계를 나타내고 있다. 저장한 아스파라가스의 품질을 변화시키는 여러 가지 요인을 고려할 때 밑부분을 물에 담그어 CA저장을 하는 것이 아스파라가스의 품질을 3주일 이상 유지시켜 주는 가장 좋은 방법이라 할 수 있겠다.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2011년도 제40회 동계학술대회 초록집
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• pp.2-2
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• 2011

Single-walled carbon nanotubes (SWNTs) have been considered as a promising candidate for nextgeneration electronics due to its extraordinary electrical properties associated with one-dimensional structure. Since diversity in electronic structure depends on geometrical features, the major concern has been focused on obtaining the diameter, chirality, and density controlled SWNTs. Despite huge efforts, the controlled synthesis of SWNTs has not been achieved. There have been various approaches to synthesize controlled SWNTs by preparation of homogeneously sized catalyst because the SWNTs diameter highly depends on catalyst nanoparticles size. In this study, geometrically controlled SWNTs were synthesized using designed catalytic layers: (a) morphologically modified Al2O3 supporting layer (Fe/Al2O3/Si), (b) Mo capping layer (Mo/Fe/Al/Si), and (c) heat-driven diffusion and subsequent evaporation process of Fe catalytic nanoparticles (Al2O3/Fe/Al2O3/Si). These results clearly revealed that (a) the grain diameter and RMS roughness of Al2O3 supporting layer play a key role as a diffusion barrier for obtaining Fe nanoparticles with a uniform and small size, (b) a density and diameter of SWNTs can be simultaneously controlled by adjusting a thickness of Mo capping layer on Fe catalytic layer, and (c) SWNTs diameter was successfully controlled within a few A scale even with its fine distribution. This precise control results in bandgap manipulation of the semiconducting SWNTs, determined by direct comparison of Raman spectra and theory of extended tight binding Kataura plot. We suggest that these results provide a simple and possible way for the direct growth of diameter, density, and bandgap controlled SWNTs by precise controlling the formation of catalytic films, which will be in demand for future electronic applications.

• 한방안이비인후피부과학회지
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• 제30권2호
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• pp.1-18
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• 2017

Objectives : This review aims to evaluate a risk of bias by risk of bias tool and RoBANS(Risk of Bias Assessment tool for Non-randomized Study) tool for clinical trial papers proving treatment effect of Korean medicines to alopecia and provides the newest reason of effectiveness of herbs to alopecia. Methods : Data were collected through electronic database including NDSL, KISS, KMBASE, Koreantk, OASIS, KoreaMed, KISTI, Pubmed, Cochrane CENTRAL and CINAHL. Two experts in Oriental Medicine assessed risk of bias of randomized controlled trials by Cochrane group's Risk of Bias tool and non-randomized controlled trials by RoBANS tool after searching, reviewing and selecting papers. Results : Total number of selected trials is 20 including 4 randomized controlled trial, 13 non-randomized controlled trials and 3 case reports. This study evaluate the risk of bias of 17 papers including 4 randomized controlled trials and 13 non-randomized controlled trials except 3 case reports by risk of bias tool and RoBANS tool. All papers of randomized controlled trials are evaluated unclear for random sequence generation and allocation concealment as there are no word on them. And all papers of non-randomized controlled trials are evaluated unclear for blinding of outcome assessments and relatively low for others. Conclusions : Korean medicine intervention can be an effective for treatment in alopecia. It was evaluated by hair density, thickness and expert panel assessment of photographs and all results are statistically significant. But enhancing levels of evidence, we must try to reduce bias in researches and report a safety, protocol and IRB.

• 한국공간구조학회논문집
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• 제18권1호
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• pp.93-100
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• 2018

The retractable roof structures have actions of various types of loads and external forces depending on the retraction and operation conditions of the roof in terms of efficiency of control and maintenance as the aspect of structural plan. In particular, there is a need for studies on the establishment of retraction controlled wind velocity to maintain the stable control and usability of roof structure against strong winds or sudden gusts during the retraction of the roof. In this paper, it was intended to provide basic materials for the development of guidelines on the operation and maintenance of domestic retractable buildings with large space by analyzing the factors affecting the retraction controlled wind velocity for the overseas stadiums with the large spatial retractable roof structures where the sliding system was applied on the steel retractable systems. As a result, the controlled wind velocity tends to decrease as the retractable roof area increases. On the other hand, the controlled wind velocity tends to increase as the retraction time increases. In addition, in the space-grid roof structures, the spherical roof structures type showed the average controlled wind velocity of 10m/sec lower than that of 17.3m/sec for curved-roof structure type, and in the curved-roof structure type, the truss roof structure showed the average controlled wind velocity of 8.9m/sec which is lower than that of 17.3m/sec for the space for the space-grid roof structure.

• The Korean Journal of Pain
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• 제6권1호
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• pp.55-59
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• 1993

Using a visual analogue scale, we compare the effect of patient-controlled analgesia and conventional intramuscular opioid regimen in 68 patients undergoing lower abdominal or gynecological surgery. We also recorded the incidence of side effects. We checked visual analogue scale 4 hours interval for 30 cases managed by patient-controlled analgesia and 38 cases of conventional intramuscular opioid group managed by obstetrician. We maintained fentanyl $0.33{\mu}g/kg/hr$ and set self administrable bolus dose $5.0{\mu}g$(lockout interval: 15 min) in patient-controlled analgesia group. Conventional intramuscular bolus injection group were administered meperidine 50 mg for 4 hour interval. Mean visual analogue scale scores obtained by patient-controlled analgesia group and intramuscular bolus injection group were $2.49{\pm}0.67$ and $4.53{\pm}1.28$(p<0.05). Side effects such as; no significant incidence of respiratory depression, urinary retention, postural hypotension, nausea, vomiting and pruritus were developed by either group. These results suggest that patient-controlled analgesia was more effective method compared with conventional intraumuscular opioid injection regimen for post-operative pain management.

• 대한물리의학회지
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• 제4권2호
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• pp.93-100
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• 2009

Purpose：The purpose of this study was to examine the effects of self-controlled knowledge of result (KR) versus the yoked KR on learning of knee joint proprioception. Methods：Forty volunteer subjects (20 men and 20 women) were randomly assigned to each four groups: 1) self-controlled KR in open kinematic chain, 2) yoked KR in open kinematic chain, 3) self controlled KR in close kinematic chain, and 4) yoked KR in close kinematic chain. The difference between the angle of position and reproduction angle was determined as a proprioception error and measured using an angle reproduction test. The subjects in self-controlled groups were provided with feedback whenever they requested it, whereas the subjects in yoked groups were not provided with feedback. The data were analyzed using a one-way ANOVA. Results：The proprioception errors in close kinematic chain groups decreased significantly compared with those in close kinematic chain groups(p<.05). The proprioception errors in the self-controlled group decreased significantly compared with those in yoked groups during acquisition and retention test(p<.05). Conclusion：Self-controlled knowledge of result during open kinematic chain movement is considered to be a good method on motor learning.

• 한방안이비인후피부과학회지
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• 제27권4호
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• pp.45-57
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• 2014

Objective : This study aims to provide fundamental data for new directions(the improvement directions) from searching research papers of randomized controlled trials among thesis of Atopic Dermatitis related to oriental medicine in Korea from 2004 to 2014 and identifying the problem and level of a clinical study through an assessment of the quality, CONSORT statement. Methods : Data was collected through the Koreanstudies Information Service System(KISS). Two experts in Oriental Medicine reviewed the title and abstract in thesis, the results of searching the title, "Atopic dermatitis" and topic, "oriental medicine" at KISS, and then they handsearched Randomized Controlled Trials related to oriental medicine in Korea. According to guidelines defined by CONSORT statement, they assessed whether 37 items were followed by guidelines at yes or no answers in order to evaluate the quality as well. They assessed the definition of each item independently. After comparing, they made a decision on the item of different outcomes through an agreement with a third party. Results : Total number of randomized controlled trials in Atopic Dermatitis related to oriental medicine is eleven. A randomized controlled trial was first published in 2007. One or two papers associated it were released every year except 2013. 9 papers of them were approved by Institutional Review Board and were received written consent. The study included between 20 to 40 subjects for 2-arm parallel study design. The effect of treatment was observed for 4 to 8 weeks. On average, the number followed guidelines was 18.64 among those of 37 CONSORT statement and 50.38% of them was followed overall. Conclusion : As an interest about randomized controlled trials was increased, it was needed to care the standard providing information of CONSORT statement on randomized controlled trials related to oriental medicine in Korea. It is suggested to provide more clear information about it, so that it can be a motive for improving quality of the journal in oriental medicine.

• 대한전기학회논문지:전기기기및에너지변환시스템부문B
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• 제52권5호
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• pp.238-245
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• 2003

In this paper, a single Phase voltage source voltage-controlled active power filter(APF) for power quality improvement was proposed. The proposed APF has the performance of harmonic suppression and unity power factor correction. The performance of harmonic suppression can be obtained by controlling the waveshape of the APF output voltage to be sine wave. And, unity power factor is controlled by the reactive power control loop of the APF output. Simulation and experimental results using diode rectifier showed that the voltage-controlled APF, unlike the current-controlled APF, can reduce the voltage harmonics as well as current harmonics. Also the results showed that the input dover factor and power quality were greatly improved.

• 한국자동차공학회논문집
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• 제6권2호
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• pp.191-202
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• 1998

An electronic-hydraulic controlled line pressure system was suggested based on the mechanical controlled CVT base model. As a high level control strategy, a 3-D optimal line pressure map was obtained considering the driver's desire, driving conditions. Also, PID type low level controller was designed. Using the high level control strategy and the dynamic models of the base model CVT with electronic controlled line pressure system, performance simulations were carried out. It is seen from the simulation results that fuel economy of the electronic controlled strategy keeps the line pressure low, which results in the improved efficiency of the hydraulic system.